Patents
Sitemap › C07 - Organic chemistry › C07D - Heterocyclic compounds › C07D 405 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
Patents for C07D 405 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom (69,397)
12/2003
12/03/2003EP1366041A1 Preparation of n-methylparoxetine and related intermediate compounds
12/03/2003EP1366028A1 Diaminoquinazoline esters for use as dihydrofolate reductase inhibitors
12/03/2003EP1135383B1 Mixed paroxetine propan-2-ol solvates
12/03/2003EP1117659B1 Substituted 3-cyanoquinolines as protein tyrosine kinases inhibitors
12/03/2003EP0937070B1 Benzoheterocyclic distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
12/03/2003EP0693072B1 Method for the synthesis of 4- and/or 5-(di)substituted 2-aminoimidazoles from 2-aminoimidazoles and aldehydes
12/03/2003CN1460101A Novel compounds inhibiting factor Xa activity
12/03/2003CN1129604C Amino acid derivatives and their use as thrombin inhibitors
12/03/2003CN1129598C Itraconazole with improved solubility, method of preparing same and pharmaceutical composition for oral administration comprising same
12/03/2003CN1129591C O-substituted hydroxycumaranone derivatives as antitumor and antimetastatic agents
12/03/2003CN1129584C Pyrimidinyloxyalkanoic amide derivatives and fungicides for agricultural and horiticultural use
12/03/2003CN1129583C Compound as intermediates for use in preparation of optically active 2-imidazoline-5-one or 2-imidazoline-5-thionone derivatives
12/03/2003CN1129578C Tetrahydrobenzindole derivs
12/03/2003CN1129576C Phenyl heterocyclic compound used as epoxy enzyme-2 inhibitor
12/03/2003CN1129428C Endothelin receptor antagonists
12/02/2003US6657085 By reacting nitro compounds with hydrazine at elevated temperature in the presence of an aqueous base; intermediates in the preparation of herbicides of the isobenzofuranone type
12/02/2003US6657062 Chemical intermediates for paroxetine derivatives; formylation, resolution, reduction, salt formation, catalysis
12/02/2003US6657060 Neuropeptide Y antagonists; treatment of eating disorders such as obesity and hyperphagia
12/02/2003US6656959 PDE IV inhibiting pyridine derivatives
12/02/2003US6656957 Pyridine derivatives
12/02/2003US6656954 Such as N-hydroxy-2-(((4-phenoxyphenyl)-sulfonyl)methyl) benzamide which inhibits matrix metalloprotease activity
12/02/2003US6656946 For treating diseases, particularly tumoral diseases, diseases of the lungs and respiratory tract
12/02/2003US6656939 Pyrazole compounds useful as protein kinase inhibitors
12/02/2003US6656933 Novel compounds which inhibit production of cytokines involved in inflammatory processes
12/02/2003CA2249756C New indanol compounds, their preparation process and the pharmaceutical compositions containing them
11/2003
11/27/2003WO2003097638A1 (s)-4-amino-5-chloro-2-methoxy-n-[1-[1-(2-tetrahydrofurylcarbonyl)-4-piperidinylmethyl]-4-piperidinyl]benzamide, process for the preparation thereof, pharmaceutical composition containing the same, and intermediate therefor
11/27/2003WO2003097636A1 Novel compounds and their use
11/27/2003WO2003097633A1 2-thio-substituted imidazole derivatives and their use in pharmaceutics
11/27/2003WO2003097613A1 Pyridazin-3(2h)-one derivatives as pde4 inhibitors
11/27/2003WO2003097610A1 Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
11/27/2003WO2003097609A1 N-substituted tricyclic 3-aminopyrazoles as pdfg receptor inhibitors
11/27/2003WO2003097604A1 Pyridine carboxamide derivatives and their use as pesticides
11/27/2003WO2003097599A1 Preparation of 4-(4-fluorophenyl)-n-substitutednipecotinate esters
11/27/2003WO2003097593A2 Protease inhibitors
11/27/2003WO2003097586A1 Aminotetralin-derived urea modulators of vanilloid vr1 receptor
11/27/2003WO2003097053A1 Compounds, compositions, and methods
11/27/2003WO2003097044A1 Methods using a combination of a 3-heteroaryl-2-indolinone and a cyclooxygenase-2 inhibitor for the treatment of neoplasia
11/27/2003WO2003096991A2 Amelioration of the development of cataracts and other opthalmic diseases
11/27/2003WO2003084464A3 Benzopyran derivatives substituted with secondary amines including tetrazole, method for the preparation thereof and pharmaceutical compositions containing them
11/27/2003WO2003074508B1 Compounds and methods of treating cell proliferative diseases
11/27/2003WO2003065983A3 11-beta-hydroxysteroid dehydrogenase 1 inhibitors useful for the treatment of diabetes, obesity and dyslipidemia
11/27/2003WO2003037338A3 Modulators of the cholesterol biosynthetic pathway
11/27/2003WO2003024899A3 CYCLIC HYDROXAMIC ACIDS AS INHIBITORS OF MATRIX METALLOPROTEINASES AND/OR TNF-α CONVERTING ENZYME (TACE)
11/27/2003WO2002103008A3 Templated molecules and methods for using such molecules
11/27/2003WO2002079170A3 Pyrimidine-2,4,6-trione derivatives, processes for their production and pharmaceutical agents containing them
11/27/2003US20030220507 Enantioselective transformation of alpha,beta-unsaturated ketones using chiral organic catalysts
11/27/2003US20030220499 Novel spiro compounds
11/27/2003US20030220494 Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
11/27/2003US20030220423 A polymerization catalyst for free radical polymerization of ethylenically unsaturated monomers
11/27/2003US20030220388 Indoline derivatives
11/27/2003US20030220385 Nitrogen compounds such as 1-benzyl-3-(5'-hydroxymethyl-2'-furyl)-6-fluoroindazole, administered as phosphodiesterases inhibitors for prophylaxis of cardiovascular or sexual disorders, or as hypotensive agents
11/27/2003US20030220371 Administering to a mammal an aromatic or heteroaromatic ring substituted triazole derivative to treat the conditions mediated by angiogenesis, such as cancer, haemangioma, proliferative retinopathy, rheumatoid arthritis, and obesity
11/27/2003US20030220370 Preparation of 4-(4-fluorophenyl)-N-alkylnipecotinate esters, 4-(4-fluorophenyl)-N-arylnipecotinate esters and 4-(4-fluorophenyl)-N-aralkylnipecotinate esters
11/27/2003US20030220368 Superior Na+ channel inhibition activity; antiarrhythmic agents
11/27/2003US20030220367 Administering a therapeutical carbamate derivative to a patient as prostaglandin IP (12 or PGI2) antagonists
11/27/2003US20030220366 Nicotinamide derivatives useful as PDE4 inhibitors
11/27/2003US20030220360 Tricyclic condensed heterocyclic compounds containing o, s in the ring, and atleast one hydroxy group, useful as antiasthmatic drugs
11/27/2003US20030220359 Substituted pyrimidine-sulfonamide derivatives are used as endothelin receptor antagonists
11/27/2003US20030220357 Reacting an aniline derivative with an acylchloride to form an intermeidate, cyclizing the intermediate, replacing hydroxy group with a leaving group (chloride), racting the product with an amino-heterocyclic compound
11/27/2003US20030220354 Quinazoline ditosylate salt compounds
11/27/2003US20030220347 Compounds and methods for treatment of asthma, allergy and inflammatory disorders
11/27/2003US20030220338 Fungal efflux pump inhibitors
11/27/2003US20030220332 Useful in the treatment of inter alia benign prostatic hyperplasia
11/27/2003US20030220330 Anilinopyrimidine derivatives as JNK pathway inhibitors and compositions and methods related thereto
11/27/2003US20030220327 Cyanamide, alkoxyamino, and urea derivatives of 1,3-benzodiazephine as HIV reverse transcriptase inhibitors
11/27/2003US20030220316 Such as N-(1-(1-methylethyl)piperidin-4-yl)-N-((4-methyl phenyl)methyl)-4-methoxyphenylacetamide for stimulation of serotonin receptors
11/27/2003CA2486097A1 N-substituted tricyclic 3-aminopyrazoles as pdfg receptor inhibitors
11/27/2003CA2486092A1 Aminotetralin-derived urea modulators of vanilloid vr1 receptor
11/27/2003CA2485896A1 Pyridazin-3(2h)-one derivatives as pde4 inhibitors
11/27/2003CA2484512A1 Treatment of cataracts and other ophthalmic diseases
11/27/2003CA2484324A1 Methods using a combination of a 3-heteroaryl-2-indolinone and a cyclooxygenase-2 inhibitor for the treatment of neoplasia
11/27/2003CA2483619A1 Novel compounds and their use
11/27/2003CA2483368A1 (s)-4-amino-5-chloro-2-methoxy-n-¬1-¬1-(2-tetrahydrofurylcarbonyl)-4-piperidinylmethyl|-4-piperidinyl|benzamide, process for the preparation thefeof, pharmaceutical composition containing the same, and intermediate therefor
11/26/2003EP1364959A1 Crystal of pyrimidine nucleoside derivative
11/26/2003EP1364945A1 Benzimidazolidinone derivatives
11/26/2003EP1363907A2 Heterocycle carboxamides as antiviral agents
11/26/2003EP1363906A2 Heterocyclic inhibitors of erk2 and uses thereof
11/26/2003EP1363904A1 Pyrazoles as tgf inhibitors
11/26/2003EP1363903A1 Indole derivatives and their use as gnrh antagonists
11/26/2003EP1363902A1 Chemical compounds
11/26/2003EP1363900A1 Isoindole-imide compounds as tnf-inhibitors
11/26/2003EP1363899A1 Quinazolone derivatives as alpha 1a/b adrenergic receptor antagonists
11/26/2003EP1363898A1 Compounds useful as modulators of melanocortin receptors and pharmaceutical compositions comprising same
11/26/2003EP1363897A2 Antagonists of mcp-1 function and methods of use thereof
11/26/2003EP1363889A1 Novel diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres
11/26/2003EP1363887A1 Substituted quinolinecarboxamides as antiviral agents
11/26/2003EP1363884A2 Pyridine-substituted benzanilides as potassium ion channel openers
11/26/2003EP1363881A2 N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
11/26/2003EP1363702A1 Methods of inhibiting kinases
11/26/2003EP1363638A2 Use of gal3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods
11/26/2003EP1363631A2 Compounds useful as modulators of melanocortin receptors and pharmaceutical compositions comprising same
11/26/2003EP1363621A1 Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
11/26/2003EP1204659B1 Serotonergic benzofurans
11/26/2003EP1176982B1 Prucalopride oral solution
11/26/2003EP1119559B1 3-phenyl-pyrones
11/26/2003EP1025095B1 Substituted chroman derivatives
11/26/2003EP1000028B1 Gastrokinetic monocyclic benzamides of 3- or 4-substituted 4-(aminomethyl)-piperidine derivatives
11/26/2003EP0689436B1 Taxanes not having an oxo group at c-9 and pharmaceutical compositions containing same
11/26/2003EP0673937B1 Bicyclic heterocyclic sulfonamide and sulfonic ester derivatives
11/26/2003CN1458923A Substituted amino-aza-cycloalkanes useful against malaria
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