Patents
Patents for C07D 405 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom (69,397)
10/2004
10/21/2004US20040209882 e.g., 2-{[4-(Cyclohexylmethyl-amino)-6-(3-fluoro-4-methoxy-phenylamino)-[1,35]triazin-2-ylamino]-methyl}-cyclopentanone; treating unwanted cellular proliferation, an inflammation mediated disease, or a hyperproliferative disease, or modulating a glycosidase enzyme
10/21/2004US20040209881 e.g., N-Cycloheptyl-N'(1-ethyl-pyrrolidin-2-ylmethyl)-6-(3-fluoro-4-methoxy-phenoxy)-[1,3,5]triazine-2,4-diamine; treating unwanted cellular proliferation, an inflammation mediated disease, or a hyperproliferative disease, or modulating a glycosidase enzyme
10/21/2004US20040209880 e.g., 6-(3-Chloro-4-methoxy-phenoxy)-N-cycloheptyl-N'-methyl-N'-(1-methyl-piperidin-4-yl)-[1,3 ,5]triazine-2,4-diamine; inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells and inhibit smooth muscle proliferation.
10/21/2004US20040209874 Hydantoins and related heterocycles as inhibitors of matrix metalloproteinases and/or TNF-alpha converting enzyme (TACE)
10/21/2004US20040209865 use for reducing body weight and treating urinary incontinence; Melanin-concentrating hormone (MCH); 5-(4-chloro-phenyl)-2-[5-(2-pyrrolidin-1-yl-ethoxy)-pyridin-2-yl-ethynyl]-pyridine for example
10/21/2004US20040209862 use treating Human Immunodeficiency Virus (HIV) , or genetically related retroviral, infection or a resulting acquired immunodeficiency syndrome (AIDS); 2-[4-(3,5-dichlorobenzyl)-3,5-diethyl-1H-pyrazol-1-yl]ethanol; reverse transcriptase inhibitors
10/21/2004US20040209860 compounds having a (biphenyl-2-yl)oxycarbonylamino- or (biphenyl-2-yl)aminocarbonylamino-substituted (2-7C)azacycloalkyl or (5-10C)azabicycloalkyl group; and a 2-(4-hydroxyphenyl)-2-hydroxyethylamino group; treating asthma or chronic obstructive pulmonary disease; providing bronchodilation
10/21/2004US20040209847 treating and preventing a variety of diseases and conditions such as aging, Alzheimer's Disease, cancer, cardiovascular disease, diabetic retinopathy, dyslipidemia, dyslipoproteinemia, hypertension, impotence, insulin resistance, peroxisome proliferator activated receptor associated disorders
10/21/2004US20040209846 Heterocyclic analgesic compounds and methods of use thereof
10/21/2004DE10316081A1 Neue Verbindungen mit antibakterieller Aktivität New compounds with antibacterial activity
10/21/2004CA2522214A1 4-phenyl-piperidine compounds and their use as modulators of opioid receptors
10/21/2004CA2522023A1 Novel heterocyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them
10/21/2004CA2521903A1 Process for preparing 5-(4-fluorophenyl)-1-[2-((2r,4r)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)ethyl]-2-isopropyl-4-phenyl-1h-pyrrole-3-carboxylic acid phenylamide
10/21/2004CA2521899A1 4- (4-(heterocyclylalkoxy}phenyl)-1-(heterocyclyl-carbonyl)piperidine derivatives and related compounds as histamine h3 antagonists for the treatment of neurological diseases suchas alzheimer's
10/21/2004CA2521788A1 Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists
10/21/2004CA2521606A1 Novel methods for the treatment of inflammatory diseases
10/21/2004CA2521433A1 Piperidine derivatives as renin
10/21/2004CA2521227A1 Substituted pyrazole compounds
10/21/2004CA2521202A1 1,3,4-substituted pyrazoles for use as 5-ht receptor antagonists in the treatment of psychoses and neurological disorders
10/21/2004CA2521201A1 Substituted pyrazoles for use in the prophylaxis or treatment of a disease which can be influenced by the binding of the substitued pyrazoles to 5ht receptors
10/21/2004CA2521199A1 Pyrazole compounds
10/21/2004CA2518916A1 Pi-3 kinase inhibitor prodrugs
10/20/2004EP1468999A1 Substituted piperidine and piperazine derivatives as melanocortin-4 receptor modulators
10/20/2004EP1468687A1 Compounds for the treatment of cancer
10/20/2004EP1468684A1 Sigma receptor binder containing indanone derivative
10/20/2004EP1467991A1 Prucalopride-n-oxide
10/20/2004EP1467990A1 Process for producing dioxolane nucleoside analogues
10/20/2004EP1467989A1 Proline compounds as ns3-serine protease inhibitors for use in treatment of hepatitis c virus infection
10/20/2004EP1467986A1 Aza-cyclic compounds as modulators of acetylcholine receptors
10/20/2004EP1467982A1 Glucocorticoid mimetics, methods of making them, pharmaceutical formulations containing them, and uses thereof
10/20/2004EP1467977A1 Novel antibacterial compounds:process for their preparation and pharmaceutical compositions containing them.
10/20/2004EP1467976A1 N-pyrazinyl-phenylsulphonamides and their use in the treatment of chemokine mediated diseases
10/20/2004EP1467974A1 Benzimidazole derivatives and their use as gnrh antagonists
10/20/2004EP1467972A1 Indazole compounds useful as protein kinase inhibitors
10/20/2004EP1467727A1 1,3-disubstituted and 1,3,3,-trisubstituted pyrrolidines as histamine-3 receptor ligands and their therapeutic applications
10/20/2004EP1467721A2 Substituted amine derivatives and their use for the treatment of angiogenesis
10/20/2004EP1467695A2 Hiv integrase inhibitors
10/20/2004EP1289964B1 Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists
10/20/2004EP1261588B1 IMIDAZOLE COMPOUNDS AS Alpha2-ADRENOCEPTORS ANTAGONISTS
10/20/2004EP1246619B1 Urotensin-ii receptor antagonists
10/20/2004EP1131291B1 4-aroyl-piperidin-ccr-3 receptor antagonists iii
10/20/2004EP1109551A4 4-amino-3-mercapto-1,2,4-triazoles
10/20/2004CN1539014A Templated molecules and methods for using such molecules
10/20/2004CN1538960A Amino-phthalazinone derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containint them
10/20/2004CN1538956A Spiro compounds
10/20/2004CN1538845A Phenyl derivatives as factor Xa inhibitors
10/20/2004CN1538836A Substituted amine derivatives and method of use
10/20/2004CN1171880C Pesticidal triazine derivatives
10/20/2004CN1171879C Herbicidal 3-aryl-1,2,4-triazole derivative
10/20/2004CN1171871C 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators
10/20/2004CN1171870C Inhibitors of cysteine protease
10/19/2004US6806367 Process for producing carbonyl hydrazones
10/19/2004US6806288 Cyclooxygenase-2 mediated disorders; reduces inflammation; fewer side effects
10/19/2004US6806287 2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses
10/19/2004US6806286 Pyrrolecarboxamides and pyrrolethioamides as fungicides
10/19/2004US6806282 Branched substituted amino derivatives of 3-amino-1-phenyl-1h-[1,2,4]triazol, methods for producing them and pharmaceutical compositions containing them
10/19/2004US6806278 Amino-tetralin derivatives as muscarinic receptor antagonists
10/19/2004US6806276 2-oxoquinoline compounds and pharmaceutical uses thereof
10/19/2004US6806230 Pyrimidine derivatives and herbicides containing them
10/19/2004CA2296901C Piperidine derivates having anxiolytic effect
10/14/2004WO2004087714A1 Indole acetamides as inhibitors of the hepatitis c virus ns5b polymerase
10/14/2004WO2004087692A1 Chromenone indoles
10/14/2004WO2004087690A2 Benzimidazole derivatives and their use for modulating the gaba-a receptor complex
10/14/2004WO2004087687A1 Chromene derivatives as anti-inflammatory agents
10/14/2004WO2004087686A2 Benzopyran compounds useful for treating inflammatory conditions
10/14/2004WO2004087680A1 Novel quinazoline derivatives and methods of treatment related to the use thereof
10/14/2004WO2004087679A1 2, 4, 6-trisubstituted pyrimidine derivatives useful for the treatment of neoplastic and autoimmune diseases
10/14/2004WO2004087677A2 Pyrimidin-4-one derivatives and their use as p38 kinase modulators
10/14/2004WO2004087673A2 Migrastatin analogs and uses thereof
10/14/2004WO2004087672A1 Migrastatin analog compositions and uses thereof
10/14/2004WO2004087669A1 Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof
10/14/2004WO2004087662A1 4-(2-phenylsulfanyl-phenyl)-1,2,3,6-tetrahydropyridine derivatives as serotonin reuptake inhibitors
10/14/2004WO2004087163A2 Pharmacokinetics modifying chemotherapy
10/14/2004WO2004087156A1 4-(2-phenylsulfanyl-phenyl)-piperidine derivatives as serotonin reuptake inhibitors
10/14/2004WO2004087155A1 4-(2-phenyloxyphenyl)-piperidine or -1,2,3,6-tetrahydropyridine derivatives as serotonin reuptake inhibitors
10/14/2004WO2004087151A1 Medicinal composition
10/14/2004WO2004087150A1 Drug composition
10/14/2004WO2004087149A1 Medicinal composition
10/14/2004WO2004087148A1 Remedy and/or preventive for lung diseases
10/14/2004WO2004087147A1 Remedy and/or preventive for lung diseases
10/14/2004WO2004087146A1 Processes for production of fine particle mixtures
10/14/2004WO2004087142A1 Quinoline-2-one-derivatives for the treatment of airways diseases
10/14/2004WO2004087051A2 Ophthalmic compositions for treating ocular hypertension
10/14/2004WO2004071448A3 Substituted azole derivatives as inhibitors of protein tyrosine phosphatases
10/14/2004WO2004037176A3 Quinazolinones and derivatives thereof as factor xa inhibitors
10/14/2004US20040204591 Reacting an amide compound containing hydroxy and a carboxyl group and having benzene ring, with a halogenated alkyl aminocarbonyl-pyrrolidine with 2-fluoro groups substituted at the ring carbon, by amindation of amine and carboxyl group
10/14/2004US20040204586 Inhibitors of macrophage migration inhibitory factor and methods for identifying the same
10/14/2004US20040204582 Substituted sulfonamides and ureas useful for inhibiting kinase activity
10/14/2004US20040204477 For use as antiproliferative agents
10/14/2004US20040204455 For therapy of hypertension, and congestive heart failure
10/14/2004US20040204454 Lactam-containing cyclic diamines and derivatives as factor Xa inhibitors
10/14/2004US20040204453 For therapy of irritable bowel syndrome, drug addiction or dependency, including alcohol addiction, depression, anxiety, schizophrenia, anxiety, schizophrenia and eating disorders
10/14/2004US20040204450 For therapy of atherosclerosis, coronary artery disease, coronary heart disease, coronary vascular disease, peripheral vascular disease, dyslipidemia, hyperbetalipoproteinemia, hypoalphalipoproteinemia, hypercholesterolemia, hypertriglyceridemia, familial-hypercholesterolemia
10/14/2004US20040204447 Isoquinolinone derivatives and their use as therapeutic agents
10/14/2004US20040204446 Nitrogen compounds such as N-(2-Fluoro-benzyl)-N-indan-2-yl-2-(3-methyl-2-o-tolyl-piperidin-1-yl) -acetamide, administered for prophylaxis arthritis, psoriasis, cardiovascular disorders, reperfusion injury or respiratory system disorders
10/14/2004US20040204437 Substituted arylamine derivatives and methods of use
10/14/2004US20040204426 4-Imidazolin-2-one compounds
10/14/2004US20040204425 Sodium channel blockers
10/14/2004US20040204421 Certain 1,3-disubstituted isoquinoline derivatives
10/14/2004US20040204412 Useful as anticoagulants in therapy and prophylaxis of cardiovascular diseases, as anti-inflammatory agents, and as metastasis inhibitors in therapy of cancer