Patents
Patents for C07D 403 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group (62,587)
12/2002
12/05/2002US20020183323 For therpay of inflammatory bowel disease, cerebral ischemia and arthritis, adult respiratory distress syndrome (ARDS) and myocarditis, as adjuvants to short term immunosuppression in transplant therapy
12/05/2002US20020183313 Cholecystokinin-A and B (CCK-A/B) antagonists and useful in therapy and prophylaxis of disorders of appetite regulatory systems (e.g., anorexia) disorders associated with intestinal smooth muscle hyperactivity (e.g., irritable bowel syndrome)
12/05/2002CA2449118A1 Cdk inhibiting pyrimidines, production thereof and their use as medicaments
12/05/2002CA2449019A1 Method for treating nerve injury caused by surgery
12/05/2002CA2447657A1 Use of compositions comprising cyclooxygenase-2 selective inhibitors in combination with radiation for inhibition or prevention of cardiovascular disease
12/05/2002CA2447475A1 Hydantion derivatives as inhibitors of matrix metalloproteinases
12/05/2002CA2447234A1 Carbazole derivatives and their use for the preparation of pharmaceutical compositions for the treatment of npy related diseases
12/05/2002CA2411549A1 Ligands of integrin receptors
12/04/2002EP1262475A1 Indole derivatives, process for preparation of the same and use thereof
12/04/2002EP1262180A1 Tnf-alpha inhibitors
12/04/2002EP1261589A1 Imidazole compounds and their use as adenosine deaminase inhibitors
12/04/2002EP1261587A1 Stilbene derivatives, their preparation and their use as antiviral agents
12/04/2002EP1261586A2 Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase iv, processes for their preparation, and their use
12/04/2002EP1261585A1 Substituted indole mannich bases
12/04/2002EP1261579A1 Dehydroamino acids
12/04/2002EP1261327A2 Adenosine receptor modulators
12/04/2002EP0907650B1 N- 4-(heteroarylmethyl)phenyl]-heteroarylamines
12/04/2002CN1383424A Aryl and heteroacrylcyclopropyl oxime ethers and their use as fungicides
12/03/2002US6489487 Triazolone derivatives, use thereof, and intermediates therefor
12/03/2002US6489475 Method of producing heterocyclic derivatives
12/03/2002US6489452 An azo dye represented by the following general formula (1) and a process for making the azo dye is disclosed. the process comprises a step in which a diazonium salt is formed by the reaction between an aminopyrazole and aromatic coupling agent
12/03/2002US6489344 For treatment diabetes in a human or animal subject
12/03/2002US6489337 Treatment of alzheimer's disease, epilepsy, eating disorders, learning and memory disorders, migraine, sleep/wake disorders, allergic rhinitis, schizophrenia, mild cognitive impairment, and asthma
12/03/2002US6489333 Heterocyclic compounds containing a guanidine mimic, for inhibition of cell adhesion, treatment of angiogenesis disorders, inflammation, cancer metastasis, diabetic retinopathy, thrombosis, restenosis, macular degeneration
12/03/2002US6489325 Inhibitors of csbp/p38, one of several kinases involved in a stress-response signal transduction, decrease the synthesis of a wide variety of pro-inflammatory proteins including, il-6, il-8, gm-csf, and cox-2
12/03/2002CA2266107C Aralkyl and aralkylidene heterocyclic lactams and imides
12/03/2002CA2117543C Dipeptidylquinazolones as anti-cancer agents
11/2002
11/28/2002WO2002095022A2 Sequence-specific dna binding compounds and their use in targeting telomeres and other dna sequences
11/28/2002WO2002094844A2 Antiviral nucleosides
11/28/2002WO2002094832A1 New benzylaminopyrimidines
11/28/2002WO2002094831A1 Novel pyridylmethylaminopyrimidines
11/28/2002WO2002094816A1 Process for the crystallization of losartan potassium
11/28/2002WO2002094796A2 Benzo[g]quinoxaline derivatives as effective compounds against infectious diseases
11/28/2002WO2002094795A1 4-aminopyrimidine derivatives
11/28/2002WO2002094793A1 Acylated 4-aminopyrazoles
11/28/2002WO2002094792A1 Herbicidal substituted benzoylpyrazoles
11/28/2002WO2002094791A1 Diamide invertebrate pest control agents containing a non-aromatic heterocyclic ring
11/28/2002WO2002094789A1 Quinoline derivatives as ligands for the neuropeptide y receptor
11/28/2002WO2002094261A1 Cxcr4-antagonistic drugs comprising nitrogen-containing compound
11/28/2002WO2002078641A3 Pyrrolidine sulfonamides
11/28/2002WO2002057223A3 Compounds azepane, preparation method therefor and pharmaceutical compositions containing said compounds
11/28/2002WO2002048106A3 Isoindolin-1-one glucokinase activators
11/28/2002WO2002000648A1 Imidazole derivatives or salts thereof and drugs containing the derivatives or the salts
11/28/2002WO2001096329A1 Medicinal compositions containing propenone derivatives
11/28/2002US20020177609 Fatty alcohol drug conjugates
11/28/2002US20020177601 Inhibit the signal transduction by tyrosine kinases; e.g. 4-(3-chloro-4-fluorophenylamino)-6-(3-(4-(methoxycarbonyl-methyl)-1 -piperazinyl)propyloxy)-7-methoxyquinazoline; use such as antitumor agent
11/28/2002US20020177600 Two or more ligand moieties covalently linked together by one or more linking groups enabling binding to multiple binding sites; increased efficacy, selectivity and duration; anti-proliferative and anticarcinogenic
11/28/2002US20020177598 Inhibit activity of chemokines, macrophage inflammatory protein-1 (MIP-1 alpha) and RANTES; 1-((4-chlorophenoxy)methyl)-carbonyl-2-methyl-4-(4-fluorobenzyl)piperazine for example
11/28/2002DE10138577A1 New 4-benzoyl-5-oxy-pyrazole derivatives, useful as herbicides, especially pre- and post-emergence selective herbicides
11/28/2002CA2826505A1 Antiviral nucleosides
11/28/2002CA2447676A1 New benzylaminopyrimidines
11/28/2002CA2447675A1 Novel pyridylmethylaminopyrimidines
11/28/2002CA2447674A1 Herbicidal substituted benzoylpyrazoles
11/28/2002CA2447020A1 The use of 4-aminopyridine derivatives for the treatment of mglur5 receptor mediated diseases
11/28/2002CA2446620A1 Antiviral nucleosides
11/28/2002CA2446324A1 Quinoline derivatives as ligands for the neuropeptide y receptor
11/28/2002CA2410763A1 Medicinal compositions containing propenone derivatives
11/28/2002CA2410391A1 Imidazole derivatives or salts thereof and drugs containing the derivatives or the salts
11/27/2002EP1260223A1 Taxanes having furyl or thienyl substituted side-chain
11/27/2002EP1259588A2 Composition and method for bleaching a substrate
11/27/2002EP1259522A1 Ligand and complex for catalytically bleaching a substrate
11/27/2002EP1259505A2 Novel 1,3-dihydro-2h-indol-2-one, preparation method and pharmaceutical compositions containing same
11/27/2002EP1259504A1 Pyrazole ether derivatives as anti-inflammatory/analgesic agents
11/27/2002EP1259493A2 Substituted piperazine compounds
11/27/2002EP1259491A1 4-imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates and amides and their use as alpha-1a agonists
11/27/2002EP1259234A1 3-heteroarylidenyl-2-indolinone compounds for modulating protein kinase activity and for use in cancer chemotherapy
11/27/2002EP1153050A4 Amino-ketone solid support templates
11/27/2002EP1001934B1 Indole compounds as cox-2 inhibitors
11/27/2002CN1382140A Neurotrophic pyrrolidines and piperidines and related compositions containing them
11/27/2002CN1382136A N-heterocyclic derivatives as NOS inhibitors
11/27/2002CN1382125A Bicycle vasporession agonists
11/27/2002CN1094939C Microbiocidal benzotriazoles compounds, making method and use
11/27/2002CN1094937C Farnesyltransferase inhibiting quinazolinones
11/27/2002CN1094929C Acetamide derivatives, process for producing the same, and medicinal composition containing the same
11/26/2002US6486329 Amorphous form of cell cycle inhibitor having improved solubility and bioavailability
11/26/2002US6486190 5-(2-imidazolinylamino)-benzimidazole derivatives, their preparation and their use as .alpha.-adrenoceptor agonists with improved metabolic stability
11/26/2002US6486188 Method of treatment for cardiovascular complications
11/26/2002US6486187 N-[4-(heteroarylmethyl)phenyl]-heteroarylamines
11/26/2002US6486165 Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith
11/26/2002US6486162 2-{3-[4-(2-t-butyl-6-trifluoromethyl-4-pyrimidinyl)-1- piperazinyl] propylthio}-4-pyrimidinol fumarate
11/26/2002US6486153 Phenylindole derivatives as 5-HT2A receptor ligands
11/26/2002CA2258285C Substituted indazole derivatives and their use as phosphodiesterase (pde) type iv and tumor necrosis factor (tnf) inhibitors
11/26/2002CA2093203C Pyrimidine derivatives and processes for the preparation thereof
11/22/2002WO2001090079A2 Novel carbamates and carbamides, production and use thereof as endothelin receptor antagonists
11/22/2002CA2410304A1 Novel carbamates and ureas production and use thereof as endothelin receptor antagonists
11/21/2002WO2002092593A1 4-(4-pyridazinyl)pyrazole derivatives
11/21/2002WO2002092578A1 Quinazoline derivatives
11/21/2002WO2002092577A1 Quinazoline derivatives
11/21/2002WO2002092576A1 Diarylurea derivatives useful as anti-inflammatory agents
11/21/2002WO2002092575A1 Benzimidazole compounds and antiviral uses thereof
11/21/2002WO2002092573A2 Heterocyclic substituted pyrazoles as inhibitors of src and other protein kinases
11/21/2002WO2002092567A1 Novel 5-phenyl-1h-indole derivatives as antagonists of interleukine-8 receptors
11/21/2002WO2002092565A2 3-aminoalkyl-2-aryl-indole derivatives and their use as gnrh antagonists
11/21/2002WO2002092096A1 Antitumor agents
11/21/2002WO2002092090A1 Substituted pyrazinones, pyridines and pyrimidines as corticotropin releasing factor ligands
11/21/2002WO2002092065A2 Novel methods for the treatment and prevention of pain using stress-activated protein kinase inhibitors
11/21/2002WO2002062290A3 Heterocyclic substituted 2-methyl-benzimidazole antiviral agents
11/21/2002WO2002022598A8 Quinolinone derivatives as tyrosine kinase inhibitors
11/21/2002US20020173659 Indole derivatives for the treatment of osteoporosis
11/21/2002US20020173646 Quinazoline derivatives and pharmaceutical compositions containing them