Patents
Patents for C07D 239 - Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings (42,619)
01/2008
01/24/2008US20080021081 e.g. 4'-2-{[(2S)-2-methylpyrrolidin-1-yl]methyl}cyclopropyl)-1,1'-biphenyl-4-carbonitrile; histamine-3 receptor ligand; neuroleptic agent, neurodegenerative diseases, cognition activator; attention-deficit hyperactivity disorder, schizophrenia, Alzheimer's disease, epilepsy, seizures, allergic rhinitis
01/24/2008US20080021055 Novel cycloalkyl derivatives as inhibitors of bone resorption and vitronectin receptor antagonists
01/24/2008US20080021054 Compositions and treatments for inhibiting kinase and/or hmg-coa reductase
01/24/2008US20080021053 Heterocyclic Derivatives
01/24/2008US20080021052 Novel glucokinase activators and methods of using same
01/24/2008US20080021050 Compounds, compositions, and methods
01/24/2008US20080021037 Isethionate salt of a selective cdk4 inhibitor
01/24/2008US20080021028 ((2S,3S) N,2-dihydroxy-5-methyl-3-{[4-(2-pyridinyl)-1-piperazinyl]carbonyl}hexanamide; for treatment and/or prevention of disorders related to autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, stroke, cancer, pre-term labor, endometriosis
01/24/2008US20080021024 Metalloprotease inhibitors
01/24/2008US20080019978 nicotinic receptor agonist useful for treating metabolic syndrome, dyslipidemia, cardiovascular diseases, disorders of the peripheral and central nervous system, hematological diseases, cancer, inflammation, respiratory diseases, gastrointestinal diseases, diabetes, and non-alcoholic fatty liver diseases
01/24/2008US20080019922 Quinazoline derivatives, their preparation, their use, and medicaments comprising them
01/24/2008US20080018237 Nitrogen-containing heterocyclic derivatives and organic electroluminescence device using the same
01/24/2008DE19934799B4 Chiral-smektische Flüssigkristallmischung und ihre Verwendung in Aktivmatrix-Displays mit hohen Kontrastwerten Chiral smectic liquid crystal composition and its use in active matrix display with high contrast
01/24/2008CA2657745A1 Pyrimidine derivatives and their use as pesticides
01/24/2008CA2657260A1 2, 4 -di (arylaminio) -pyrimidine-5-carboxamide compounds as jak kinases inhibitors
01/23/2008EP1880736A1 Releasable linkage and composition containing same
01/23/2008EP1879900A2 Sulfoximine-pyrimidine macrocycles and the salts thereof, a process for making them, and their pharmaceutical use against cancer
01/23/2008EP1879871A1 New heterocyclylethylamide derivatives
01/23/2008EP1879870A1 Antitumoral tetrahydro-pyrimidines
01/23/2008EP1879864A1 Fluorinated pyridine n-oxide thrombin modulators and process for n-oxidation of nitrogen containing heteroaryls
01/23/2008EP1644339B1 6-arylamino-5-cyano-4-pyrimidinones as pde9a inhibitors
01/23/2008EP1567498B1 Mandelic acid derivatives
01/23/2008EP1556360B1 Electroluminescent device
01/23/2008EP1556354B1 Therapeutic piperazine derivates useful for treating pain
01/23/2008EP1322651B1 Bicyclic heteroaromatic compounds
01/23/2008CN101111487A Processes for producing 4-aminoquinazolines
01/23/2008CN101111484A Process for the manufacture of a precursor of vitamin b*
01/23/2008CN101111250A Substituted 5-phenyl pyrimidines i in therapy
01/23/2008CN100363364C Substituted hexahydropyrazino(1,2-a)pyrimidin-4,7-dion derivatives, method for the production and use thereof as medicaments
01/22/2008US7321063 Sulfonamide inhibitors of aspartyl protease
01/22/2008US7321033 Having immunomodulatory activity; for therapy and prophylaxis of infections caused by adenovirus, cytomegalovirus, hepatitis A virus (HAV), hepatitis B virus (HBV), flaviviruses including Yellow Fever virus, herpes virus
01/22/2008US7320983 Sulfur compounds such as phenylmethyl [2R-hydroxy-3-[(3-methylbutyl) (phenylsulfonyl)amino]-1S-(phenylmethyl)propyl]carbamate, used for prevention of viral diseases and replication
01/22/2008US7320979 Diseases which respond to influencing by dopamine D3 receptor antagonists or agonists, diseases of the central nervous system and disturbances of kidney function; N-[6-(4-Allylpiperazin-1-yl)pyridin-3-yl]-4-isopropylbenzenesulfonamide
01/22/2008CA2420999C 2-substituted heterocyclic compounds and their use in treating multidrug resistance
01/17/2008WO2008008747A1 [4,5']bipyrimidinyl-6,4'-diamine derivatives as protein kinase inhbitors
01/17/2008WO2008008359A2 Benzofuro-and benzothienopyryimidine modulators of the histamine h4 receptor
01/17/2008WO2008008059A1 Anti-cancer agents ans uses thereof
01/17/2008WO2008006560A1 Substituted sulphoximines as tie2 inhibitors and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
01/17/2008WO2008006287A1 Inreversible protein tyrosine kinases inhibitors and the preparation methods and uses thereof
01/17/2008WO2007125405A3 Substituted 2-amino-fused heterocyclic compounds
01/17/2008WO2007120669A8 Tetrahalogenated compounds useful as inhibitors of angiogenesis
01/17/2008WO2007019080A3 Tricyclic beta-secretase inhibitors for the treatment of alzheimer's disease
01/17/2008US20080015353 Process for production of 4-acetylpyrimidines and crystals thereof
01/17/2008US20080015256 Tetralin and indane derivatives and uses thereof
01/17/2008US20080015208 3-Fluoro-N-(5-ureidomethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-benzenesulfonamide; serotonin receptors 5-HT6 and 5-HT2A ligand; neurodegenerative disorders; antidepressant, anxiolytic agent; Parkinson's disease, Huntington's disease, manic depression, psychoses, epilepsy, obesity, drug abuse
01/17/2008US20080015206 Anti-cancer cyclopenta[G]quinazoline compounds
01/17/2008US20080015200 Benzofuro- and benzothienopyrimidine modulators of the histamine H4 receptor
01/17/2008US20080015195 Novel Heteroaromatic Inhibitors of Fructose-1,6-Bisphosphatase
01/17/2008US20080015192 Inhibitors of polo-like kinases
01/17/2008US20080015185 N-heterocyclic inhibitors of tnf-alpha expression
01/17/2008US20080015183 Substituted quinazolin-4-ylamine analogues
01/17/2008US20080015182 Potent PARP Inhibitors
01/17/2008US20080014189 Diaminotriazoles useful as inhibitors of protein kinases
01/17/2008DE102006031224A1 New sulfoximine-substituted pyrimidines useful for treating e.g. diseases caused by inflammatory, allergic or proliferative processes, oncological diseases, cancer, eye, autoimmune and neurodegerative diseases
01/17/2008CA2659590A1 Irreversible protein tyrosine kinases inhibitors and the preparation methods and uses thereof
01/17/2008CA2657908A1 Benzofuro- and benzothienopyrimidine modulators of the histamine h4 receptor
01/17/2008CA2657381A1 [4,5']bipyrimidinyl-6,4'-diamine derivatives as protein kinase inhibitors
01/17/2008CA2657062A1 Substituted sulphoximines as tie2 inhibitors and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
01/16/2008EP1878727A1 2-aminoquinazoline derivatives
01/16/2008EP1878726A1 Substituted sulphoximines as Tie2 inhibitors and salts thereof, pharmaceutical compositions comprising the same, methods of preparing the same and uses of the same
01/16/2008EP1878725A2 Pyrimidine derivatives and their use as CB2 modulators
01/16/2008EP1877386A1 Herbicidally active phenylsulphonyl-urea
01/16/2008EP1877385A1 Pyrimidines and pyrazines useful as modulators of ion channels
01/16/2008EP1877384A2 Method for preparation of optionally 2-substituted 1,6-dihydro-6-oxo-4-pyrimidinecarboxylic acids
01/16/2008EP1877383A1 Quinoline and quinoxaline derivatives as inhibitors of kinase enzymatic activity
01/16/2008EP1877364A1 Phenylacetylene derivatives having mglur5 receptor affinity
01/16/2008EP1786823B1 Alkylidene tetrahydronaphthalene derivatives, method for their production and their use as anti-inflammatory agents
01/16/2008EP1601659B1 Pyrimidin-2-one compounds and their use as dopamine d3 receptor ligands
01/16/2008EP1340748B1 Quinazoline derivatives and drugs
01/16/2008CN101107234A HIV inhibiting 2-(4-cyanophenylamino) pyrimidine derivatives
01/16/2008CN101106998A Mitotic kinesin inhibitors
01/16/2008CN101104617A Dihydropyrimidine compounds and use for the same in preparing medicament for curing and preventing virosis
01/16/2008CN101104608A Solanesol derivative, preparation and application thereof
01/16/2008CN101104605A N-(4-chloro-6-methoxylpyrimidin-2-yl)-2,4-dichlorophenyloxyacetamide and its preparation method, application and agricultural composition
01/16/2008CN101104604A Optically pure dihydropyrimidine compounds and use for the same in preparing medicament for curing and preventing virosis
01/16/2008CN100361979C Process for preparing the calcium salt of rosuvastatin
01/16/2008CN100361978C 2-pyrimidine oxy-N-aryl 7-nitrile or organic phosphate benzylamine compound, its production and use thereof
01/15/2008US7319111 Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists
01/15/2008US7319104 hPPARs activators
01/15/2008US7319103 Non-imidazole tertiary amines as histamine 3 receptor inhibitors for the treatment of cognitive and sleep disorders, obesity and other CNS disorders
01/15/2008US7319099 Benzoyl-piperazine derivatives
01/10/2008WO2008006040A1 Hydroxylated and methoxylated cyclopenta [d] pyrimidines as akt protein kinase inhibitors
01/10/2008WO2008006032A1 Cyclopenta [d] pyrimidines as akt protein kinase inhibitors
01/10/2008WO2008003412A1 The use of 1,4-diaryl-dihydropyrimidine-2-on derivatives for treating pulmonary arterial hypertension
01/10/2008US20080009623 Pyrimidine compounds
01/10/2008US20080009622 Method for producing pyrimidine compound
01/10/2008US20080009509 Quinazoline Derivatives For Inhibiting Cancer Cell Growth And Method For The Preparation Thereof
01/10/2008US20080009504 enzyme inhibitors of glucan synthase;1S,2R,3R,4aR,6aS,7R,8R,10aR,10bR,12aR)-3-(acetyloxy)-2-[(2S)-2-amino-2,3-dimethylbutyloxy]-8-[(1R)-1,2-dimethyl propyl]-1,6a,8,10a-tetramethyl-6-oxo-1,3,4,6,6a,7,8,9,10,10a,10b,11,12,12a-tetradecahydro-2H-1,4a-(methanooxymethano)chrysene-7-carboxylic acid
01/10/2008US20080009494 Cycloalkyl Substituted Pyrimidinediamine Compounds And Their Uses
01/10/2008US20080009462 Metabolically Stable Alkoxyalkyl Esters of Antiviral or Antiproliferative Phosphonates, Nucleoside Phosphonates and Nucleoside Phosphates
01/10/2008US20080008682 Agonists; Treatment of Hepatitis C virus; combination with other drugs; phosphonate derivatives of purine or thiazolo(4,5-d)pyrimidine rings
01/10/2008CA2657702A1 Quinazolines and related heterocyclic comp0unds, and their therapeutic use
01/10/2008CA2656622A1 Hydroxylated and methoxylated cyclopenta [d] pyrimidines as akt protein kinase inhibitors
01/10/2008CA2656618A1 Cyclopenta [d] pyrimidines as akt protein kinase inhibitors
01/10/2008CA2656307A1 Use of 1,4-diaryldihydropyrimidin-2-one derivatives for the treatment of pulmonary arterial hypertension
01/09/2008EP1875900A2 JAK/STAT pathway inhibitors and the use thereof for the treatment of osteoarthritis
01/09/2008EP1874738A1 Pyrimidines reacting with o6-alkylguanine-dna alkyltransferase
01/09/2008EP1874733A1 Substituted cyclic urea derivatives and the use thereof as vanilloid receptor 1 modulators
01/09/2008EP1874724A2 Phenyl ethyne compounds
01/09/2008EP1874117A1 Polycyclic carbamoylpyridone derivative having hiv integrase inhibitory activity