Patents
Patents for C07D 223 - Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom (8,732)
08/2008
08/07/2008US20080188459 antiinflammatory agents; side effects rduction; less toxicity, irritation, allergic response; rheumatoid arthritis, psoriasis, asthma, Crohn's disease, ulcerative colitis, COPD ; rel-N-[(2R,10,14b)-8-cyano-1,2,3,4,10,14b-hexahydro-10-methyldibenzo[c,f]pyrido[1,2-a]azepin-2-yl]-2,2,2-trifluoroacetamide
08/07/2008US20080188458 Enzyme inhibitors; interferons; interleukins; cyclosporins; Cycloprop[d]indolo[2,1-a][2]benzazepine/indolo[2,1-a][2]benzazepine derivatives; N'-(5-((sec-Butylsulfonyl)carbamoyl)-8-cyclohexyl-11-methoxy-1,12b-dihydrocyclopropa[d]indolo[2,1-a][2]benzazepin-1a(2H)-yl)-N,N-dimethylethanediamide
08/07/2008CA2676160A1 6-oxo-6,7-dihydro-5h-dibenzo[b,d]azepin-7-yl derivatives
08/06/2008EP1951676A2 Lxr modulators
08/06/2008EP1951250A2 Chemical compounds
08/06/2008EP1951047A2 Tyrosine kinase inhibitors
08/06/2008CN101238106A Fluoro substituted 2-oxo azepan derivatives
08/06/2008CN100408563C Method for producing epsilon-caprolactam
08/05/2008US7408067 Neuregulins such as 4-(4-Hydroxyphenylthio)-piperidine trifluoroacetate for treatment of dysfunctions of central and autonomic nervous systems
08/05/2008US7407950 N-(heteroaryl)-1H-indole-2-carboxamide derivatives and their use as vanilloid TRPV1 receptor ligands
07/2008
07/30/2008EP1685103B1 3-aminopyrrolidone derivatives
07/30/2008EP1592684B1 Malonamide derivatives as gamma-secretase inhibitors
07/29/2008US7405209 Protease inhibitors
07/24/2008WO2008055068A8 Inhibitors of histone deacetylase
07/24/2008US20080177064 Dipeptidyl peptidase inhibitors
07/24/2008US20080176869 e.g. N-(4-fluorobenzyl)-3-hydroxy-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-2-carboxamide; viricide in combination with other HIV/AIDS antivirals, immunomodulators, antibiotics or vaccines; AIDS
07/24/2008US20080176833 Dihydropyridine derivatives as useful as protein kinase inhibitors
07/23/2008CN100404512C Crystalline form beta-d of the chlorohydrate of ivabradine, process for its preparation and pharmaceutical compositions containing it
07/23/2008CN100404511C 4,4-difluoro-1,2,3,4-tetrahydro-5h-1-benzoazepine derivative or salt of the same
07/22/2008US7402670 Synthesis by chiral diamine-mediated asymmetric alkylation
07/22/2008CA2310748C Substituted 11-phenyl-dibenzazepine compounds useful for the treatment or prevention of diseases characterized by abnormal cell proliferation
07/17/2008US20080171882 [(4S)-4-Methyl-2,5-dioxoimidazolidin-4-yl]methanesulfonyl chloride and [(4R)-4-methyl-2,5-dioxoimidazolidin-4-yl]methanesulfonyl chloride; chemical intermediates for enzyme inhibitors
07/17/2008US20080171735 SUCCINOYLAMINO BENZODIAZEPINES AS INHIBITORS OF Abeta PROTEIN PRODUCTION
07/16/2008EP1943217A1 Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses
07/16/2008CN100402502C Crystalline form gamma of the chlorhydrate of ivabradine, process for its preparation and phamaceutical composition containing it
07/15/2008US7399758 Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors
07/10/2008WO2008081726A1 Process for production of amide or lactam
07/10/2008WO2008053393A3 Rotary actuator
07/09/2008EP1940817A1 Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment
07/09/2008EP1940797A2 8-substituted benzoazepines as toll-like receptor modulators
07/09/2008EP1399424B1 Method for preparation of 10,11-dihydro-10-hydroxy-5h-dibenz/b,f/azepine-5-carboxamide and 10,11-dihydro-10-0x0-5h-dibenz/b,f/azepine-5-carboxamide
07/03/2008WO2007149728A3 Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma
07/03/2008US20080161286 excellent purity; bradycardic agent; myocardial ischaemia: angina pectoris, myocardial infarct, arrhythmia disturbances, heart failure; structure confirms by X-ray diffraction data; industrial scale, storage stability
07/03/2008US20080161285 Beta-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
07/02/2008CN100398520C Bengamide derivatives, method for the production thereof and use thereof for the treatment of cancer
06/2008
06/26/2008WO2008075006A1 Piperldinum compounds for treatment of obstructive pulmonary diseases ( copd)
06/26/2008US20080154036 Guanidine Compound and Asymmetric Reaction Using the Same
06/26/2008US20080153809 Novel amides useful for treating pain
06/26/2008US20080153806 diagnostic test and method is provided comprising mixing blood or another biological fluid sample with a test compound and spotting the blood on filter paper for subsequent analysis of the effect of the test compound on the blood. The biological fluid can be a cerebrospinal
06/26/2008US20080153805 Sulfonamide derivatives
06/26/2008US20080153803 Gamma-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
06/25/2008EP1935885A2 Melanin concentrating hormone receptor ligands : substituted 1-benzyl-4-aryl piperazine analogues.
06/24/2008US7390896 Preventing the deposits of amyloid protein, treating neurodegenerative disease, Alzheimer's disease and Down's Syndrome; {[carbamoyl]cycloalkyl}-N-(2-oxo-5-phenyl((S)-3H-benzo[f]1,4-diazepin-3-yl))- or (2-oxo-5-phenyl((S)-3H-benzo[f]1,4-diazepin-3-yl))-carboxamide
06/24/2008US7390830 MIP-1 alpha and/or MCP-1 antagonists; rheumatoid arthritis; nephritis; multiple sclerosis; nephropathy
06/24/2008US7390802 Substituted lactams as inhibitors of Aβ protein production
06/24/2008US7390801 Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
06/24/2008US7390797 Fused indazole compounds
06/19/2008WO2007120517A3 Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates related thereto
06/19/2008US20080146546 Bicyclic and Tricyclic Heteroaromatic Compounds
06/19/2008US20080146536 2-Aminoimidazopyridines for treating neurodegenerative diseases
06/12/2008WO2008070111A2 Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates thereof
06/12/2008US20080139811 Reacting an amino, hydroxy substituted amide with a heterocyclic substituted carboxylic acid to produce (2S,3S,5S)-2-(2,6-Dimethylphenoxyacetyl) amino-3-hydroxy-5-[2S-1-imidazolidin-2-onyl)-3-methyl-butanoyl] amino-1,6-diphenylhexane; inhibitors of HIV infection
06/12/2008US20080139807 Catalytic dehydrogenation with gaseous hydrogen of 11a,10b-dihydro-6H-dibenz/b,f/oxireno[d] azepine-6-carboxamide; anticonvulsant; chemical intermediate
06/12/2008US20080138654 hole transporting or hole conducting materials comprising diamino dianthracenes such as N*10*,N*10'*Bis-biphenyl-4-yl-N*10*,N*10'*-di-m-toly-[9,9']bianthracenyl-10,10'-diamine, for use in organic light emitting diodes, video displays, portable telephones, or computers
06/12/2008CA2670285A1 Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates thereof
06/11/2008EP1414794B1 Allylmercaptocaptopril compounds and uses thereof
06/10/2008US7384932 bradycardial agent, myocardial ischaemia, angina pectoris, myocardial infarct and associated rhythm disturbances, supraventricular rhythm disturbances, and heart failure; mixture of acetonitrile and water is preheated, ivabradine hydrochloride is added, cooled at room temperature
06/10/2008US7384518 Method for purifying lactams
06/05/2008WO2008064887A1 A bislactamamide derivative as intermediate in the production of di i socyanate
06/05/2008US20080132482 3-(2(R)-Cyclopentylmethyl-3 (S)-hydroxyl-1-oxo-5-phenylpentyl)amino-1-methyl-5-(4-fluoro-phenyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one; neurological disorders related to beta -amyloid production, Alzheimer's disease, Down's Syndrome
06/05/2008US20080132419 Producing family of tunable, pH dependent, controlled release medicants containing same active ingredient in combination with weak acid
06/05/2008DE60129697T2 Kondensierte azepinderivate und ihre verwendung als antidiuretisches mittel Condensed azepine derivatives and their use as antidiuretic agent
06/04/2008EP1926712A1 6-substituted 2,3,4,5-tetrahydro-1h-benzo[d]azepines as 5-ht2c receptor agonists
06/04/2008EP1926711A1 Novel heterobicyclic derivatives useful as inhibitors of liver carnitine palmitoyl transferase
06/04/2008CN101190892A Method for preparing monamide
05/2008
05/29/2008US20080125375 Peptide like compounds for treating coronavirus or aviviridae virus; severe acute respiratory distress syndrome
05/29/2008US20080122346 Anthrancene derivative compound and organic light-emitting device including the same
05/28/2008EP1924578A2 6-N-LINKED HETEROCYCLE-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[d]AZEPINES AS 5-HT2C RECEPTOR AGONISTS
05/28/2008EP1924561A2 6-arylalkylamino- 2,3,4,5-tetrahydro-1h-benzo[d]azepines as 5-ht2c receptor agonists
05/28/2008EP1924560A1 6-substituted- 2,3,4,5-tetrahydro-1h-benzo[d]azepines as 5-ht2c receptor agonists
05/28/2008EP1924551A2 Organic compounds
05/27/2008US7378410 3,4,5-trihydroxy-2-methoxy-8,8-dimethyl-non-enoic acid ((3S,6S)-6-azido-2-oxo-azepan-3-yl)-amide; less toxicity, better selectivity in killing cancer cells, minimal effect on normal healthy cells
05/22/2008WO2008059513A2 Compounds suitable as modulators of hdl
05/22/2008US20080119459 Trifluoromethylbenzamide Derivatives and Therapeutic Uses Thereof
05/22/2008US20080119453 Bicyclic derivatives as modulators of ion channels
05/21/2008EP1923386A2 Carbamate caspase inhibitors and uses thereof
05/21/2008CN101184735A Crystalline form of benzazepinium maleate derivative
05/21/2008CN100389108C Production method of hexyl lactam in ion liquid
05/20/2008US7375100 2-amino-pyridine derivatives useful for the treatment of diseases
05/20/2008US7375099 Malonamide derivatives
05/15/2008US20080114052 Cyclic derivatives as modulators of chemokine receptor activity
05/14/2008EP1919874A2 Process for preparing benzazepine compounds or salts thereof
05/14/2008EP1919867A2 Lisofylline analogues and their pharmeacuetical uses
05/08/2008WO2008054609A2 Dissolution and precipitation of cocrystals with ionizable components
05/08/2008WO2008012837A8 Process for producing 10-oxo-l10, 11-dihydr0-5h-dibenz [b, f] azepine-5-carboxamide starting from 5-cyanoiminostilbene
05/08/2008US20080108820 First isolated from the sponge Hemiasterella; for treatment of cancer; prevention of restenosis of blood vessels subject to traumas such as angioplasty and stenting; methods for synthetic preparation
05/08/2008CA2667826A1 Inhibitors of histone deacetylase
05/07/2008EP1918272A1 Pharmaceutically active compounds and methods of use
05/07/2008EP1603880B1 Quinolinone/benzoxazinone derivatives and uses thereof
05/07/2008CN101172967A Method for preparation of 10,11-dihydro-10-hydroxy-5h-dibenz/b,f/azepine-5-carboxamide and 10,11-dihydro-10-0x0-5h-dibenz/b,f/azepine-5-carboxamide
05/06/2008US7368566 Process and intermediates for preparing benzazepines
05/06/2008US7368465 Metalloproteinase inhibitors
05/06/2008US7368444 4-Hydroxy-1-toluenesulfonyl-2,3,4,5-tetrahydro-1H-1-benzazepine, for example; useful as the preventive and/or treatment medicine against diseases caused by stress
05/02/2008WO2008049808A1 Mtp inhibiting tetrahydro-naphthalene-1-carboxylic acid derivatives
05/02/2008WO2007135293A3 2-alkoxy-3,4,5-trihydroxy-alkylamide-benzazepines, the preparation and use thereof, and compositions containing the same
05/02/2008CA2664143A1 Mtp inhibiting tetrahydro-naphthalene-1-carboxylic acid derivatives
05/01/2008US20080103129 Heterocyclic derived metalloprotease inhibitors
05/01/2008US20080103128 Lactams substituted by cyclic succinates as inhibitors of abetta protein production
04/2008
04/30/2008EP1915346A1 Asymmetric catalytic reduction of oxcarbazepine
04/30/2008EP1915345A1 Fluoro substituted 2-oxo azepan derivatives
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