Patents
Patents for C07D 223 - Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom (8,732)
08/2010
08/17/2010CA2427227C Lactam compound
08/17/2010CA2425497C (n)-((s)-2-hydroxy-3-methyl-butyryl-1-(l-alaninyl)-(s)-1-amino-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepin-2-one dihydrate and its use in the treatment of alzheimer's disease
08/12/2010WO2010089475A1 Novel method for the synthesis of ivabradine and the pharmaceutically acceptable acid addition salts thereof
08/12/2010CA2750089A1 Novel method for the synthesis of ivabradine and the pharmaceutically acceptable acid addition salts thereof
08/11/2010EP1487763B1 Use of microfabricated devices for radiosynthesis
08/11/2010CN1827600B Crystalline form beta of the chlorhydrate of ivabradine, process for its preparation and pharamcetuical composition containing it
08/11/2010CN101801377A Anti-inflammatory composition
08/10/2010US7772432 amidation of a heteroary substituted oxoaminobenzoic acid with an amine; for treatment of psoriasis and rheumatoid arthritis using e.g. N-(3-dimethylaminophenyl)-3-(3-methoxybenzamido)-4-methylbenzamide
08/10/2010US7772247 vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) receptor antagonists such as 1-(4-(2-(N-methoxy-N-methylcarbamoyl)thieno[3,2-b]pyridin-7yloxy)-3-fluorophenyl)-3-(2-phenylacetyl)thiourea, used as antiproliferative agents
08/10/2010US7772225 N-sulfamoyl-piperidineamides for the treatment or inhibition of obesity and related conditions
08/05/2010US20100197664 Novel b1-antagonists
08/05/2010US20100197660 Azepine derivatives as gamma-secretase inhibitors
08/04/2010EP2212293A1 Heterocycle amide t-type calcium channel antagonists
08/04/2010CN101792417A Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases
07/2010
07/29/2010US20100191475 Method for identification and functional characterization of agents which modulate ion channel activity
07/29/2010US20100190753 Methods and Compositions for Treating Amyloid-Related Diseases
07/29/2010US20100190688 Tetrapeptide analogs
07/28/2010CN101786987A Extraction equipment of caprolactam
07/28/2010CN101786986A (+)-meptazinol prodrug or salt thereof and preparation method thereof
07/28/2010CN101786010A Catalyst for preparing caprolactam by gas phase Beckmann rearrangement method and preparation method thereof
07/22/2010WO2010081342A1 Methods for the preparation of ivabradine sulfate and form i crystal thereof
07/22/2010WO2010041943A3 METHOD FOR PREPARING ε-CAPROLACTAM FROM N-ACYL-6-AMINOCAPROIC ACID
07/22/2010US20100184741 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
07/21/2010CN101784524A Ionic liquids
07/21/2010CN101781249A Synthesis method of 10-oxa-10,11-dihydro-5H-dibenzo(b,f) azepine
07/21/2010CN101781248A Method for synthesizing N-methylhexahydroazepin-4-one hydrochloride, azelastine hydrochloride intermediate
07/20/2010US7759388 Phenylalanine derivatives
07/20/2010US7759336 chemokine receptor antagonists such as N-(4-azepan-1-ylpyrimidin-2-yl)ethane-1,2-diamine, used for the treatment and prevention of inflammatory diseases, allergic diseases, acquired immunodeficiency syndrome infection with human immunodeficiency virus
07/20/2010CA2431982C Novel benzazepines and related heterocyclic derivatives which are useful as orexin receptor antagonists
07/15/2010WO2010079324A1 Ammoximation process
07/15/2010US20100179317 Ammoximation process
07/15/2010US20100179316 Process for the preparation of ivabradine hydrochloride and polymorph thereof
07/14/2010CN101778826A Azepine derivatives as gamma-secretase inhibitors
07/14/2010CN101774969A Ivabradine sulfate and method for preparing type I crystal thereof
07/13/2010US7754750 a -5 substituted 1-H,3-H-imidazolidine-2,4-dione such as 5-(2-{[4-(4'-fluoro[1,1'-biphenyl]-4-yl)-1-piperazinyl]sulfonyl}ethyl)-2,4-imidazolidinedione; protease inhibitors, especially metalloelastase (MMP12)
07/13/2010US7754709 Tetracyclic thiophenepyrimidinone compounds as inhibitors of 17β hydroxysteroid dehydrogenase compounds
07/13/2010CA2567776C Vasopressin v1a antagonists
07/08/2010US20100173894 Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases
07/08/2010US20100173893 Preparation of eslicarbazepine and related compounds by asymmetric hydrogenation
07/08/2010US20100173890 Compounds, Process for their Preparation, Intermediates, Pharmaceutical Compositions and their use in the Treatment of 5-HT6 Mediated Disorders such as Alzheimer's Disease, Cognitive Disorders, Cognitive Impairment Associated with Schizophrenia, Obesity and Parkinson's Disease
07/08/2010US20100173880 Alkaloid aminoester derivatives and medicinal composition thereof
07/08/2010US20100173824 Azepinoindole Derivatives As Pharmaceutical Agents
07/07/2010EP1940817B1 Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment
07/07/2010CN101768176A Ionic liquid
07/07/2010CN101768117A New crystalline form of hydrochloric acid Ivabradine and preparation method thereof
07/07/2010CN101768116A Preparation method for Ivabradine
07/07/2010CN101768100A N-(4-nitrophenylmethyl) lactam compound and preparation method thereof
07/07/2010CN101767860A Recovery process of caprolactam refining raffinate
07/06/2010US7749993 Utillizing vasopressin antagonistic agent such as 5-dimethylamino-1-[4-(2-methylbenzoylamino)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepine; safe with few side effects
07/06/2010US7749992 modulators of Cholesterol ester transfer protein activity, such as 5-[Acetyl-(3,5-bis-trifluoromethyl-benzyl)-amino]-7-trifluoromethyl-2,3,4,5-tetrahydro-benzo[b]azepine-1-carboxylic acid isopropyl ester, for treating or preventing cardiovascular disorders
07/01/2010WO2010072930A1 Novel method for the synthesis of ivabradine
07/01/2010WO2010072409A1 Process for preparation of ivabradine
07/01/2010WO2010011924A3 Monomers derived from alpha-or beta-amino-e-caprolactam and polymers made therefrom
07/01/2010US20100168083 Adamantane derivatives for the treatment of the metabolic syndrome
06/2010
06/30/2010EP2202225A1 New method for synthesising ivabradine and its added salts with a pharmaceutically acceptable acid.
06/30/2010EP1735270B1 Diamino alcohols and their use as renin inhibitors
06/30/2010CN101759643A New method for synthesising ivabradine and its added salts with a pharmaceutically acceptable acid.
06/24/2010US20100160628 Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
06/24/2010US20100160627 (2,3-cis)-3-amino-2-phenyl-2,3-dihydro-1,5-benzoxazepin-4(5H)-one; for treatment of neurological disorders related to amyloid beta protein production such as Alzheimer's disease; inhibit gamma secretase and thereby inhibit the production of amyloid beta protein
06/24/2010US20100160296 Use of imipramine blue and analogs thereof in treating cancers
06/24/2010US20100160293 Solid Ophthalmic Drug for External Use
06/24/2010US20100159596 Small molecule compounds for stem cell differentiation
06/24/2010US20100158818 Antimicrobial n-chlorinated compositions
06/23/2010CN1875004B Resolution of a narwedine amide derivative
06/23/2010CN101747324A Sulfonamide derivatives
06/23/2010CN101747248A Method for preparation of hexanolactam with 5-formoxyl methyl valerate
06/23/2010CN101307021B Chemical synthesis process for iminostilbene
06/22/2010US7741317 LXR modulators
06/17/2010US20100152165 Carboxylic acid derivatives
06/17/2010US20100152125 Compositions And Methods For The Diagnosis, Treatment, And Prevention Of Amyotrophic Lateral Sclerosis And Related Neurological Diseases
06/16/2010CN1805938B Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases
06/15/2010US7737142 (Thio) carbamoyl-cyclohexane derivatives as D3/D2 receptor antagonists
06/15/2010CA2564369C Delta crystalline form of ivabradine chlorhydrate, process for its preparation and pharmaceutical compositions containing it
06/10/2010WO2010064871A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same
06/10/2010US20100145040 Benzazepine Derivatives For The Treatment of Neurological Disorders
06/10/2010US20100145003 Catalytic Deamination for Caprolactam Production
06/09/2010EP2194139A1 Biochemical synthesis of 6 amino caproic acid
06/09/2010CN101723897A Method for synthesizing Ivabradine
06/03/2010WO2010062107A1 Organic electroluminscent device using electroluminescent compounds
06/03/2010US20100137582 N-pyridylpiperidine compound, method for producing the same, and pest control agent
06/02/2010EP2190820A2 Substituted azepine- and diazepine-sulfonamides useful to inhibit 11beta-hydroxysteroid dehydrogenase type-1
06/02/2010CN1926240B Biochemical synthesis of 6-amino caproic acid
06/01/2010US7727997 N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives
05/2010
05/27/2010US20100130477 Spirocyclobutyl Piperidine Derivatives
05/27/2010US20100129473 AMINO SUBSTITUTED DIARYL[a,d]CYCLOHEPTENE ANALOGS AS MUSCARINIC AGONISTS AND METHODS OF TREATMENT OF NEUROPSYCHIATRIC DISORDERS
05/26/2010EP2189448A1 Processes for the Separation of 3-Benzazepine Racemates
05/26/2010EP1315709B1 Aminoalkylbenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same
05/26/2010CN1953963B Process for producing cyclic N-hydroxyimide compound
05/26/2010CN101712650A Method for synthesizing caprolactam in one step by liquid phase hydrogenation of nitrocyclohexane
05/26/2010CN101168524B Method for preparing low sulfonated caprolactam
05/25/2010US7723514 Method of preparing a 5H-dibenz(b,f)azepine-5-carboxamide
05/25/2010US7723384 1H-2-Benzazepine-1,5(2H)-dione derivatives in which the N is connected via alkylene to a saturated or monounsaterated nitrogen heterocycle, e.g.,2-(3-{4-[2-tert-Butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl}propyl)-3,4-dihydro-1H-2-benzazepine-1,5(2H)-dione; dopamine-3 receptor modulators
05/25/2010CA2496723C New process for synthesizing ivrabradine and its pharmaceutically acceptable acid addition salts
05/25/2010CA2362273C Benzazepine-n-ethanoic acid derivatives for treating secondary hypertension
05/19/2010EP2186516A1 Novel benzazepine derivative
05/19/2010EP2185151A1 Anti-inflammatory composition
05/19/2010CN101709053A Process for preparing caprolactam
05/18/2010US7718795 Succinoylamino benzodiazepines as inhibitors of aβ protein production
05/18/2010US7718675 Diamino alcohols and their use as renin inhibitor
05/18/2010US7718658 Saturated ring with 2 nitrogens, 1 of which is 2-(o-(difluoromethyl)phenyl)quinazol-4-yl-substituted and the other is oxyalkanoyl-substituted; inhibitors of voltage-gated sodium channels and calcium channels; treating acute, chronic, neuropathic, or inflammatory pain
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