Patents for C07D 223 - Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom (8,732) |
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02/18/2010 | US20100041639 Cyclic malonamides as inhibitors of a beta protein production |
02/18/2010 | US20100039024 New Heterocyclic bridged biphenyls |
02/17/2010 | EP1347950B1 Derivatives of 4-hydroxybutanoic acid and of its higher homologue as ligands of gamma-hydroxybutyrate (ghb) receptors, pharmaceutical compositions containing same and pharmaceutical uses |
02/16/2010 | US7662956 Ethyl[7-chloro-5-(2-chloroprene)-1-isobutyl-2-oxo-1,2,4,5-tetrahydrobenzo[d]azepin-3-yl]-acetate; dyslipidaemia, arteriosclerosis, restenosis and ischemia |
02/16/2010 | US7662809 13-Cyclohexyl-5-(2-pyrrolidin-1-ylethoxy)-6,7-dihydro-5H-indolo[2.1-a][2]benzazepine-10-carboxylic acid, for example; use for the treatment or prevention of infection by hepatitis C virus |
02/16/2010 | CA2537414C .beta. crystalline form of ivabradine chlorhydrate, process for the preparation thereof and pharmaceutical compounds containing it |
02/16/2010 | CA2445329C 20-hydroxyeicosatetraenoic acid production inhibitors |
02/11/2010 | WO2009092071A3 Amino acid and peptide pro-drugs of phenolic analgesics and uses thereof |
02/11/2010 | US20100035861 Meptazinol Biligand Derivatives and/or their Salts, Preparation Method and Uses Thereof |
02/09/2010 | CA2192092C Arylsulfonamido-substituted hydroxamic acids as matrix metalloproteinase inhibitors |
02/04/2010 | WO2010012812A1 Benzazepines and benzazocines as sigma-receptor ligandes |
02/04/2010 | US20100029935 Optically active quaternary ammonium salt having axial asymmetry, and method for producing alpha-amino acid and derivative thereof by using the same |
02/04/2010 | DE102008035596A1 Derivate benzoannelierter Stickstoff-Heterocyclen Derivatives benzoannelierter nitrogen heterocycles |
02/03/2010 | EP2149562A1 method of preparing (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride hemihydrate |
02/03/2010 | CN100586927C Amide derivatives and their use as inhibitors of 11-beta-hydroxysteroid dehydrogenase |
02/02/2010 | US7655647 3-[(1-oxo-2-cyclopropylmethyl-heptyl)]amino-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one; amyloid precursor protein and beta -peptide inhibitor; beta or gamma secretases inhibitor; amyloid plaques and neurofibrillar tangles; neurodegenerative diseases: Alzheimer's disease; Down syndrome |
02/02/2010 | CA2345838C Method for the synthesis of radiolabeled compounds |
02/02/2010 | CA2333963C Carboxylic acids and carboxylic acid isosteres of n-heterocyclic compounds |
01/28/2010 | WO2010011967A1 Methods of making cyclic amide monomers, and related derivatives and methods |
01/28/2010 | WO2010011924A2 Monomers derived from alpha-or beta-amino-e-caprolactam and polymers made therefrom |
01/28/2010 | CA2734991A1 Activation of histone deacetylase 1 (hdac1) protects against dna damage and increases neuronal survival |
01/27/2010 | EP2146722A1 Aryl- and heteroaryl-substituted tetrahydrobenzo-1,4-diazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin |
01/27/2010 | EP2146720A1 Aryloxy-and heteroaryloxy-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin |
01/26/2010 | US7652004 7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid, 13-cyclohexyl-3-methoxy-6-[3-(4-morpholinylcarbonyl)-2-pyridinyl]-, 1,1-dimethylethyl ester; 7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid, 13-cyclohexyl-3-methoxy-6-[2-(4-morpholinylcarbonyl)phenyl]-, 1,1-dimethylethyl ester |
01/21/2010 | WO2010007382A1 Benzazepine derivatives and their use as hstamine h3 antagonists |
01/21/2010 | WO2010007253A2 Novel method for preparing functionalized benzocyclobutenes, and use in the synthesis of ivabradine and of addition salts thereof with a pharmaceutically acceptable acid |
01/21/2010 | WO2010007027A1 Selective hydroxamic acid based mmp-12 and mmp-13 inhibitors |
01/21/2010 | US20100016580 Process for the preparation of functionalised benzocyclobutenes, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid |
01/21/2010 | US20100016291 Mtp inhibiting tetrahydro-naphthalene-1-carboxylic acid derivatives |
01/21/2010 | US20100016287 Compounds having affinity for dopamine d3 receptor and uses thereof" |
01/21/2010 | US20100016286 Anti-Inflammatory Agents |
01/21/2010 | CA2731196A1 Benzazepine derivatives and their use as hstamine h3 antagonists |
01/21/2010 | CA2730708A1 Selective hydroxamic acid based mmp-12 and mmp-13 inhibitors |
01/20/2010 | EP2145871A1 New method for preparing functionalised benzocyclobutenes and its application to the synthesis of ivabradine and its addition salts with a pharmaceutically acceptable acid. |
01/20/2010 | CN101628894A Method for preparing 3-(S)- amino-2,3,4,5-tetrahydro-2-oxy-1H-1-benzazepin-1-tert-butyl acetate |
01/20/2010 | CN100582095C Method for chiral inversion of (S)-(+)- and (R)-(-)-10,11-dihydro-10-hydroxy-5h-dibenz/b,f/azepine-5-carboxamide and optically enriched mixtures thereof |
01/14/2010 | US20100009966 Substituted lactams as inhibitors of abeta protein production |
01/14/2010 | US20100009965 Cyclic malonamides as inhibitors of abeta protein production |
01/14/2010 | US20100009959 Pentacyclic Indole Derivatives as Antiviral Agents |
01/13/2010 | EP1706501B1 Biochemical synthesis of 6-amino caproic acid |
01/13/2010 | CN101624372A Lactam compound |
01/07/2010 | WO2010000197A1 A method for preparing 5h-cyano-imido stilbene |
01/07/2010 | WO2010000196A1 Method for chemical synthesis of oxcarbazepine |
01/07/2010 | US20100004228 calcitonin gene related peptide antagonists such as [(3-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-1-[4-[1-(3-ethoxy-3-oxopropyl)piperidin-4-yl]piperidin-1-yl]-1-oxopropan-2-yl]4-(3-oxo-5-phenyl-1H-1,2,4-triazol-2-yl)piperidine-1-carboxylate; headaches; diabetes; irritable bowel syndrome; hot flashes |
01/07/2010 | US20100004223 Crystalline Forms Of (R)-8-Chloro-1-Methyl-2,3,4,5-Tetrahydro-1H-3-Benzazepine Hydrochloride |
01/06/2010 | EP2139886A1 Quinolone and tetrahydroquinoline and related compounds having nos inhibitory activity |
01/06/2010 | CN101622232A 6-oxo-6,7-dihydro-5H-dibenzo[B,D]azepin-7-yl derivatives |
01/06/2010 | CN100577171C Medicament for treating severe heart failure |
01/05/2010 | US7642280 Inhibitors of acyl glucosaminyl inositol amidase and methods of use |
01/05/2010 | US7642251 Compounds for the treatment of hepatitis C |
01/05/2010 | CA2395601C Dibenzo (b,f) azepine intermediates |
01/05/2010 | CA2318192C .beta.2-adrenergic receptor agonists |
12/31/2009 | US20090325930 Selective estrogen receptor modulator |
12/31/2009 | US20090325900 Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof |
12/30/2009 | WO2009158005A1 Benzazepinone compounds |
12/30/2009 | WO2009157196A1 Amide compound |
12/30/2009 | EP1558577B1 Substituted 4-phenyl-piperidin-amides as tachykinin antagonists and serotonin reptake inhibitors |
12/30/2009 | CN101613317A Mozavaptan synthesis technology for treating congestive heart failure (CHF) |
12/29/2009 | US7638320 Bengamide derivatives, process for preparing them, and their use |
12/24/2009 | US20090318682 Process for the synthesis of 7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid |
12/24/2009 | US20090318423 Ion Channel Modulators & Uses Thereof |
12/24/2009 | US20090318420 crystal structured 3-[3-[[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one hydrochloride, used for treating angina pectoris, myocardial necrosis, and congestive heart failure; bradycardial agents |
12/24/2009 | US20090318419 Delta-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it |
12/24/2009 | US20090318418 Delta d-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it |
12/24/2009 | US20090318417 a crystal stuctured form of 3-{3-[{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino]-propyl}-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one hydrochloride, useful as bradycardial agents |
12/23/2009 | EP2135861A1 Process for the synthesis of the 7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one, and its application to the synthesis of ivabradine as well as its addition salts with a pharmaceutically acceptable acid |
12/23/2009 | EP1879564B1 Compounds to treat amyloidosis and prevent death of beta-cells in type 2 diabetes mellitus |
12/23/2009 | EP1858843B1 Process for making caprolactam |
12/23/2009 | CN101607939A Process for the synthesis of the 7,8-dimethoxy-1,3-dihydro-2h-3-benzazepin-2-one, and its application to the synthesis of ivabradine as well as its addition salts with a pharmaceutically acceptable ac |
12/17/2009 | WO2009150838A1 Process for producing amide or lactam |
12/17/2009 | WO2009066041A3 Derivatives of 1,2,4,5-tetrahydro-3h-benzazepines, preparation method therefor and pharmaceutical compositions containing same |
12/17/2009 | US20090312307 Heterocyclo inhibitors of potassium channel function |
12/16/2009 | EP2133340A1 Novel benzazepine derivatives |
12/16/2009 | EP2131846A1 Novel dosage form |
12/16/2009 | CN101602731A Metalloproteinase inhibitors |
12/15/2009 | US7632944 Bacterial pathogens; multiantibiotic-resistant: Staphylococcus aureus, Enterococcus fecalis, and Enterococcus fectum, Streptococcus pneumoniae, Escherichia coil; amination of quinolone carboxylic acid derivatives by azepine derivatives |
12/15/2009 | CA2537400C .gamma. crystalline form of ivabradine chlorhydrate, process for the preparation thereof and pharmaceutical compounds containing it |
12/10/2009 | US20090306141 Novel Compounds |
12/09/2009 | EP1435964B1 Novel prodrugs of n-h bond-containing compounds and methods of making thereof |
12/09/2009 | EP1280768B1 Method for producing caprolactam from 6-aminocapronitrile |
12/09/2009 | EP1182183B1 Anthracene derivatives and organic electroluminescent devices made by using the same |
12/09/2009 | CN101597261A Amorphous ivabradine hydrochloride |
12/09/2009 | CN101596437A Fluid distributor of polyphase reactor suitable for toluene method caprolactam technology |
12/03/2009 | WO2009143630A1 Creatine sugar amides and salts thereof |
12/03/2009 | US20090298781 Compounds for the inhibition of apoptosis |
12/02/2009 | CN100564354C Separation of 6-aminocapronitrile and hexamethylenediamine from a mixture comprising hexamethylenediamine, 6-aminocapronitrile and tetrahydroazepine |
12/01/2009 | US7625934 Metalloproteinase inhibitors |
11/24/2009 | US7622462 Benzazepine derivatives and uses thereof |
11/19/2009 | WO2009139001A2 An improved process for the preparation of oxcarbazepine |
11/19/2009 | US20090286993 Process for producing cyclic n-hydroxy imide compounds |
11/19/2009 | US20090286771 2-Phenoxy- and 2-Phenylsulfonamide Derivatives with CCR3 Antagonistic Activity for the Treatment of Inflammatory or Immunological Disorders |
11/18/2009 | EP2119702A1 Amide derivative |
11/17/2009 | CA2402236C Method for separating an azepine derivative out of a mixture containing an amine and an azepine derivative |
11/12/2009 | WO2009071631A3 Dibenzoazepine and dibenzooxazepine trpa1 agonists |
11/12/2009 | US20090281308 Chemokine receptor binding heterocyclic compounds with enhanced efficacy |
11/12/2009 | US20090281085 3-(4-fluorophenyl)-3-hydroxy-2-amino-propionic acid amides and related compounds having analgesic activity |
11/11/2009 | EP2116529A1 Process for production of amide or lactam |
11/11/2009 | EP1606255B1 Cyclic derivatives as modulators of chemokine receptor activity |
11/11/2009 | CN100558722C A method for the preparation of enantiomerically pure mirtazapine |
11/11/2009 | CN100558708C Method for preparing monamide |