Patents
Patents for C07D 223 - Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom (8,732)
10/2008
10/23/2008US20080262045 N-{[(4S)-2,5-dioxoimidazolidinyl]methyl}-4-(4-fluorophenoxy)benzenesulfonamide and N-{[(4S)-2,5-dioxoimidazolidinyl]methyl}[1,1'-biphenyl]-4-sulfonamide; chemical intermediates for enzyme inhibitors; especially as inhibitors of MMP12
10/23/2008US20080261950 Drug hybrid of rivastigmine or physostigmine with tranylcypromine, amoxapine, desipramine, nortriptyline, protriptyline, fluoxetine, fluvoxamine, paroxetine, duloxetine, betahistine, amlodipine, proylhexedrine, rimantadine, desloratadine; Alzheimer's disease; Parkinson's disease, impairment in memory
10/22/2008EP1596868B1 Method for treating severe heart failure and medicament therefor
10/22/2008CN101289426A Process for preparing restraining agent for leishmaniasis
10/21/2008US7439397 reacting methyl bromide and 2-[(1R)-3-(diisopropylamino)-1-phenylpropyl]-4-(trifluoromethyl) phenol; formation of (3R)-3-[2-hydroxy-5-(trifluoromethyl)phenyl]-N,N-diisopropyl-N-methyl-3-phenylpropan-1-aminium bromide; asthma, chronic obstructive pulmonary disorder, allergic and infectious rhinitis
10/16/2008US20080255154 Cycloalkylcarbonyl-3H-spiro[2-benzofuran-1,3'-pyrrolidin]-3-ones: N-methyl-5-[4-(1-{[3-oxo-1'H,3H-spiro[2-benzofuran-1,3'-pyrrolidin]-1'-yl]carbonyl}cyclopropyl)phenyl]pyridine-2-carboxamide; 11- beta hydroxyl steroid dehydrogenase type 1 inhibitors; mineralcorticoid receptor antagonists; diabetes
10/16/2008US20080255095 Benzylamine analogues
10/16/2008US20080255092 6-Substituted-2,3,4,5-Tetrahydro-1H-Benzo[d]Azepines as 5-Ht2c Receptor Agonists
10/16/2008US20080255089 Menopausal or postmenopausal disorders, vasomotor symptoms, urogenital disorders, female sexual dysfunction, breast cancer, depression, diabetes, bone demineralization, and osteoporosis; substituted 2-(p-aminoalkoxyphenyl)-1,1-diphenylethylene derivatives
10/15/2008EP1680127B1 Benzazepine derivatives as mao-b inhibitors
10/15/2008CN101287719A Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment
10/15/2008CN101284813A Preparation method of ivabradine
10/14/2008US7435824 Prodrugs of potassium channel inhibitors
10/14/2008US7435729 using estrogen antagonist ; anticancer agents
10/14/2008CA2309328C Cyclic amine derivatives and their use as drugs
10/09/2008US20080249300 reacting a mixture of cyclic ketones with ammonia and hydrogen peroxide, in the presence of titanium silicalite catalysts and cocatalysts comprising a mixture of a Bronsted acid and ammonia, in solvents, to give ketone oximes, then preparing lactams by Beckmann rearrangement, using the ketone oximes
10/08/2008EP1976385A2 Anthranilamide derivatives and their use for the control of insects and acari
10/08/2008CN101279971A 4,4-difluoro-1,2,3,4-tetrahydro-5h-1-benzoazepine derivative or salt of the same
10/02/2008WO2008116308A1 Quinolone and tetrahydroquinoline and related compounds having nos inhibitory activity
10/02/2008US20080242698 Antiepilrptic agents; antiischemic agents; vision defects; skin disorders; muscular disorders; anticonvulsants;analgesics; Parkinson's disease; huntington's disease; amyotrophic lateral sclerosis; multiple sclerosis
10/02/2008CA2681771A1 Quinolone and tetrahydroquinoline and related compounds having nos inhibitory activity
10/01/2008EP1975156A1 Method for depolymerizing polyamide and method for producing monomer of polyamide
10/01/2008EP1399424B8 Method for preparation of 10,11-dihydro-10-hydroxy-5h-dibenz/b,f/azepine-5-carboxamide and 10,11-dihydro-10-0x0-5h-dibenz/b,f/azepine-5-carboxamide
10/01/2008CN101277937A Asymmetric catalytic reduction of oxcarbazepine
10/01/2008CN101274911A Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases
09/2008
09/30/2008US7429603 C-fms kinase inhibitors
09/30/2008US7429579 antagonism/inhibition, of the D3 receptor; substance abuse.
09/30/2008US7429578 e.g. phenyl-3,4-dihydropyrrolo[4,3,2-de]isoquinolin-5-(1H)-one; anticarcinogenic agent; stroke, head trauma, and neurodegenerative disease; potentiating cytotoxicity of a DNA-damaging cytotoxic agent or ionizing radiation
09/25/2008US20080234252 2-[4-(4-Chlorophenyl)-5-(methoxymethyl)-4H-1,2,4-triazol-3-yl]isoindoline; vasopressin antagonists; dysmenorrhea, Alzheimer's disease, anorexia nervosa, anxiety, anxiety disorder, asthma, atherosclerosis, autism, cardiovascular disease
09/25/2008US20080234251 8-Substituted Benzoazepines as Toll-Like Receptor Modulators
09/25/2008US20080234247 Heterocyclic analgesic compounds and methods of use thereof
09/25/2008US20080230368 Process for the purification of lactams
09/24/2008CN101273017A Method of manufacturing benzoazepin compound or its salt
09/23/2008US7427683 Such as 5-nitro-furan-2-carboxylic acid (2-piperidin-1-yl-phenyl)-amide; diabetes, angiogenesis, psoriasis, restenosis, schizophrenia, rheumatoid arthritis, cardiovascular disease, cancer
09/23/2008US7427631 especially as inhibitors of MMP12
09/23/2008US7427611 4-[(3-aminopropyl) (ethyl)amino]-2-{[1-(carboxymethyl)-2-oxo-2, 3, 4, 5-tetrahydro-1H-1benzazepin-3-yl]amino}carbonyl)-cyclopentyl]methyl}-4-oxobutanoic acid; neutral endopeptidase or human soluble endopeptidase (hSEP) inhibitors; cardiovascular diseases, apoptosis, stroke, neurodegenerative disorder
09/18/2008WO2007104933A8 Chemical compounds
09/18/2008US20080227771 Delta d-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
09/18/2008US20080227769 Compounds for the Treatment of Hepatitis C
09/18/2008US20080227724 3-(alkanoyl or alkenoyl)amino-caprolactams; autoimmune diseases, asthma, osteoporosis, transplant rejection, psoriasis, Alzheimer's Disease, Multiple sclerosis, ALS; antitumor, antiarthritic, antifibrotic, and antiscarring agents
09/17/2008EP1968938A1 Substituted propiolic acid amides and their use for producing drugs
09/17/2008EP1446383B1 Monohydroxycarbamazepine for use in the preparation of a medicament for the treatment of affective and attention disorder and neuropathic pain
09/17/2008CN100418967C Tricyclic inhibitors of poly(ADP-ribose) polymerases
09/17/2008CN100418955C Novel Benzo-fused heterocycles
09/17/2008CN100418951C Cycloamine derivative and its use as medicine
09/16/2008US7425551 N [(S)-5-(2-hydroxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-2-methyl-N '-(2,2,3,3,3-pentafluoro-propyl)-malonamide; Alzheimer's disease; cancers; gamma -secretase inhibitors; good solubility, potentiation and selectivity
09/12/2008WO2008108639A1 Co-crystalline forms of carbamazepine
09/11/2008US20080221320 Hydrolysis of the nitrile group of 5-cyano-10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine with hydrogen peroxide, or a Group 1A or 2A perborate or persulfate, in alkaline ethanol or isopropanol and in the presence of microwaves
09/11/2008US20080221087 Substituted lactams as inhibitors of abeta protein production
09/11/2008US20080221083 Heterobicyclic metalloprotease inhibitors
09/11/2008US20080221082 of the alpha V beta 3 integrin receptor; , thromboembolic events, cardiovascular disorders, lung diseases, disorders of the CNS, the kidney, the gastrointestinal tract or inflammation
09/10/2008CN101263116A Novel heterobicyclic derivatives useful as inhibitors of liver carnitine palmitoyl transferase
09/09/2008US7423033 Hydroxyalkanoylaminolactams and related structures as inhibitors of aβ protein production
09/09/2008US7423032 Method for treating severe heart failure and medicament therefor
09/09/2008US7423031 Compounds and compositions as protein kinase inhibitors
09/09/2008US7422676 Apparatus and process for the synthesis of hydrogen peroxide directly from hydrogen and oxygen
09/04/2008WO2008105445A1 Transdermal pharmaceutical composition
09/04/2008WO2008104589A1 Novel dosage form
09/04/2008WO2008064887A8 A bislactamamide derivative as intermediate in the production of di i socyanate
09/04/2008US20080214525 Alkyl 4- [4- (5-Oxo-2,3,5, 11A-Tetrahydo-5H-Pyrrolo [2, 1-C] [1,4] Benzodiazepine-8-Yloxy) -Butyrylamino]-1H-Pyrrole-2-Carboxylate Derivatives and Related Compounds For the Treatment of a Proliferative Disease
09/04/2008US20080214523 Method for treating severe heart failure and medicament therefor
09/04/2008US20080214520 e.g. 7-Chloro-3-(2,2,2-trifluoroacetyl)-6-trifluoromethanesulfonyloxy-2,3,4,5-tetrahydro-1H-benzo[d]azepine; antidepressant, anxiolytic agent; obesity, obsessive/compulsive disorder
09/04/2008CA2679525A1 Novel dosage form
09/03/2008EP1962600A2 Metronidazole cocrystals and imipramine cocrystals
09/03/2008EP1257541B1 Polypharmacophoric agents
09/03/2008CN101258131A 6-arylalkylamino- 2,3,4,5-tetrahydro-1h-benzo[d]azepines as 5-ht2c receptor agonists
08/2008
08/28/2008WO2008059513A3 Compounds suitable as modulators of hdl
08/28/2008US20080207898 Processes for the preparation of aminoethoxybenzyl alcohols
08/28/2008US20080207897 6-Substituted-2,3,4,5-Tetrahydro-1H-Benzo[D] Azepines as 5-Ht2c Receptro Agonists
08/28/2008US20080207602 Succinoylamino benzodiazepines as inhibitors of abeta protein production
08/28/2008US20080206191 Compounds for the Treatment of Hepatitis C
08/27/2008EP1960347A2 17-beta-hydroxysteroid dehydrogenase type 3 (17beta-hsd3) inhibitors
08/27/2008CN101253153A 6-substituted-2,3,4,5-tetrahydro-1H-benzo[d] azepines as 5-HT2c receptor agonists
08/27/2008CN101253147A Organic compounds
08/27/2008CN101250148A Method for preparing caprolactam by phase rearrangement of cyclohexanone oxime liquid
08/27/2008CN100413861C Compounds and methods for the treatment or prevention of flavivirus infections
08/21/2008WO2008053393A8 Rotary actuator
08/21/2008WO2007145922A3 Benzazepinones as sodium channel blockers
08/20/2008EP1958938A2 A process for the preparation of 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide
08/20/2008EP1958937A1 Delta d Crystaline form of ivabradine hydrochloride, process of preparation thereof and pharmaceutical compositions containing the same
08/20/2008EP1692129B1 Keto lactam compounds and use thereof
08/20/2008EP1337251B1 Monocyclic or bicyclic carbocycles and heterocycles as factor xa inhibitors
08/20/2008CN101248062A C-fms kinase inhibitors
08/19/2008US7414078 Oral general anesthetics and metabolitically resistant anticonvulsants
08/19/2008US7414045 Substituted pyrimido[1,2-a]azepines useful as HIV integrase inhibitors
08/14/2008WO2008097546A2 Compounds that inhibit cholinesterase
08/14/2008US20080194541 Anti-Inflammatory Agents
08/14/2008CA2677241A1 Compounds that inhibit cholinesterase
08/13/2008EP1956005A1 Delta d Crystaline form of ivabradine hydrochloride, process of preparation thereof and pharmaceutical compositions containing the same
08/13/2008CN100410240C Continuous process for preparing caprolactam
08/12/2008US7411072 e.g. 5-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-ylidenemethyl)-3H-benzooxazol-2-one; antiinflammatory, antidiabetic agent; electrolytes and water retention modulator; hypotensive, hypoglycemic agent; arrhythmias, myocardial fibrosis, osteoporosis, polyuria, polydipsia, Crohn's disease
08/12/2008US7410962 Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them
08/12/2008US7410961 2,6-disubstituted piperiddines as modulators
08/12/2008CA2487331C Anti-inflammatory compositions and methods of use
08/07/2008WO2008093737A1 Amide derivative
08/07/2008WO2008092786A1 6-oxo-6,7-dihydro-5h-dibenzo[b,d]azepin-7-yl derivatives
08/07/2008WO2008070111A3 Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates thereof
08/07/2008US20080188463 6-oxo-6,7-dihydro-5h-dibenzo[b,d]azepin-7-yl derivatives
08/07/2008US20080188462 reversed chloroquines; to treat chloroquine resistant/sensitive malaria parasites; N'-(7-Chloro-quinolin-4-yl)-N-[3-(10,11-dihydro-dibenzo[b,f]azepin-5-yl)-propyl]-N-methyl-propane-1,3-diamine
08/07/2008US20080188460 Tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them
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