Patents
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
07/2005
07/14/2005CA2550649A1 3-(4-piperidine-1ylmethyl-phenyl)-propion acid-phenylamide-derivatives and related compounds used in the form of mch antagonists (melanine concentrating hormone) for treating eating disorders
07/14/2005CA2546981A1 Optically active, heteroaromatic .beta.-hydroxy esters, processes for their preparation from .beta.-keto esters and processes for the preparation of these .beta.-keto esters
07/13/2005EP1551834A1 Substituted quinazolinone compounds
07/13/2005CN1639150A 异喹啉衍生物 Isoquinoline derivatives
07/13/2005CN1639127A Process for asymmetric hydrogenation of hexahydroquinoline salts
07/13/2005CN1639125A New inhibitors of histone deacetylase
07/13/2005CN1639119A Substituted 2-amino-cycloalkanecarboxamides and their use as cysteine protease inhibitors
07/13/2005CN1636986A Benzophenones as inhibitors of reverse transcriptase
07/13/2005CN1636985A Benzophenones as inhibitors of reverse transcriptase
07/13/2005CN1636984A Benzophenones as inhibitors of reverse transcriptase
07/12/2005US6916957 Antiinflammatory agents; antihistamines; antiallergens
07/12/2005US6916905 Dmt-Tic di-and tri-peptidic derivatives and related compositions and methods of use
07/12/2005US6916850 Pyruvate derivatives
07/12/2005US6916837 Such as 2-(6-amidino-2-naphthyloxy)-5-methanesulfonyl-aminobenzoic acid trifluoroacetate; blood coaggulation factor VII inhibitors
07/12/2005US6916830 Substituted tetrahydroisoquinolines as C5a receptor modulators
07/07/2005WO2005061460A1 Compounds, compositions, and methods
07/07/2005WO2005061459A1 Biaryl sulfonamides and methods for using same
07/07/2005WO2005060456A2 Method for treating adamts-5-associate disease
07/07/2005US20050148776 Process for asymmetric hydrogenation of hexahydroquinoline salts
07/07/2005US20050148648 Cystic fibrosis transmembrane conductance regulator; ABC transporter mediated diseases like cystic fibrosis; 5-methoxy-N-((1-(3,4-dimethoxyphenyl)-cyclohexyl)methyl)benzofuran-2-carboxamide; or sulfonamide analogs; chloride or bicarbonate channel modulators
07/07/2005US20050148625 Use of estrogen antagonists and estrogen agonists inhibiting pathological conditions
07/07/2005US20050148624 Enzyme inhibitors with isoquinolinone structures
07/07/2005US20050148613 Carbonylamino-derivatives as novel inhibitors of histone deacetylase
07/07/2005US20050148584 N-(3-(2-(4-morpholino)ethyloxy)phenyl)-N-{(cis3-(benzylamino)cyclohexyl)methyl}-N'-phenylurea; useful for the treatment of gastrointestinal reflux disorders, eating disorders leading to obesity and irritable bowel syndrome
07/07/2005CA2548513A1 Biaryl sulfonamides and methods for using same
07/07/2005CA2547575A1 Method for treating adamts-5-associated disease
07/06/2005EP1549685A1 Novel nitrosation polymer in organic synthesis
07/06/2005EP1485357B1 Process for asymmetric hydrogenation of hexahydroquinoline salts
07/06/2005CN1634892A Method for resolution of isoquinolines
06/2005
06/30/2005WO2005058884A2 Cyclopropane compounds and pharmaceutical use thereof
06/30/2005US20050143415 For the production of a pharmaceutical agent for therapy of inflammatory diseases
06/30/2005CA2549660A1 Cyclopropane compounds and pharmaceutical use thereof
06/29/2005EP1546116A1 Vanilloid receptor ligands and their use in treatments
06/29/2005EP1546089A2 Aryl and heteroaryl compounds and methods to modulate coagulation
06/29/2005EP1432686B1 Tetrahydroisochinolines, their production and the use thereof as analgesics
06/29/2005CN1633413A 20-hydroxyeicosatetraenoic acid production inhibitors
06/29/2005CN1633296A Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
06/28/2005US6911456 Related to organ systems which respond to estrogen agonists or antagonists; in particular, 2-phenyl-3-aroylbenzothiophenes and 1-(alkylaminoethoxy phenyl)-1-phenyl-2-phenylbut-1-enes have wide application as estrogen agonists
06/28/2005US6911453 Substituted 4-phenyltetrahydroisoquinolinium, process for their preparation, their use as a medicament, and medicament containing them
06/23/2005WO2005056013A1 Dpp-iv inhibitors
06/23/2005WO2002068380A8 Synthetic excitatory amino acids
06/23/2005US20050137200 Potassium channel modulators; antiarrhythmia agents
06/22/2005EP1544194A1 4-(substituted aryl)-5-hydroxyisoquinolinone derivative
06/22/2005EP1542967A1 Amide and sulfonamide ligands for the estrogen receptor
06/22/2005EP1542692A1 Amino-pyridine, -pyridine and pyridazine derivatives for use as vanilloid receptor ligands for the treatment of pain
06/22/2005EP1320523B1 Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases
06/22/2005EP1268466B1 Decahydro-isoquinolines
06/22/2005CN1630642A Benzenesulfonamide derivatives
06/22/2005CN1630640A Novel enantiomer of tetra hydrogen isoquinoline derivative and officinal salt, preparation and pharmaceutical composition thereof
06/22/2005CN1206914C Pesticide containing 0-benzyl oximeether derivative and its use
06/21/2005US6908931 1-(2,2-diphenyl-ethyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline- 2-carbaldehyde; for treating sleep disorders
06/21/2005US6908911 Antibacterial agents
06/16/2005WO2005054202A1 7-phenyl-isoquinoline-5-sulfonylamino derivatives as inhibitors of akt (proteinkinase b)
06/16/2005WO2005054176A1 Peroxisome proliferator activated receptor modulators
06/16/2005WO2005053610A2 Diamine and iminodiacetic acid hydroxamic acid derivatives
06/16/2005WO2005040150A3 Glutamine fructose-6-phosphate amidotransferase (gfat) inhibitors
06/16/2005US20050131231 Process for preparing cyclic N-substituted alpha-imino carboxlic acids
06/16/2005US20050131032 (Oxime)carbamoyl fatty acid amide hydrolase inhibitors
06/16/2005US20050130979 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) or the quinoxalinedione is 9-methyl-amino-6-nitro-hexahydro-benzo(F) quinoxalinedione (PNQX) for treating demyelinating disorders
06/16/2005US20050130973 3-Methyl-2-[4'-(pyridin-3-ylmethoxymethyl)-biphenyl-4-sulfonylamino]-butyric acid; metalloproteinase inhibitors; arthritis, macular degeneration, graft versus host disease, cancer, osteoarthritis
06/16/2005CA2547356A1 Diamine and iminodiacetic acid hydroxamic acid derivatives
06/16/2005CA2547212A1 Peroxisome proliferator activated receptor modulators
06/15/2005EP1541559A1 5-substituted isoquinoline derivative
06/15/2005EP1541148A1 Dpp-iv inhibitors
06/15/2005EP1539701A1 Caspase inhibitors and uses thereof
06/15/2005EP1539697A1 Phosphodiesterase 4 inhibitors, including n-substituted aniline and diphenylamine analogs
06/15/2005EP1539687A1 Substituted glycine derivatives for use as medicaments
06/15/2005EP1539678A1 3,4-di-substituted cyclobutene-1, 2-diones as cxc-chemokine receptor ligands
06/15/2005EP1373240B1 Retinoid x receptor modulators
06/15/2005CN1628107A Heteroaryl alkyl piperazine derivatives as fatty acid oxidation inhibitors
06/15/2005CN1626540A Iridium compound and organic electroluminescent device using the same
06/14/2005US6906072 Central nervous system disorders
06/09/2005WO2005051945A1 Heterocyclic compounds as modulators of peroxisome proliferator activated receptors, useful for the treatment and/or prevention of disorders modulated by a ppar
06/09/2005WO2005051391A1 Quinazolinone compounds with reduced bioaccumulation
06/09/2005US20050124654 Compounds and methods of use
06/09/2005US20050124652 Guanidino compounds
06/09/2005US20050124614 E. g., 3,5-bis-trifluoromethylphenyl)-4-[(furan-2-ylmethyl)-aminocarbonyl]-2-methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline;anticarcinogenic agents; antitumor agents; antiproliferative agents; activators of the caspase cascades; enzyme inhibitors used in combination with radiation or chemotherapy
06/09/2005US20050124605 E.g., substituted 2,3,5,10b-tetraaza-benzo[e]azulen-6-yl)-acetic acids, 2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(4,6-dimethoxy-pyrimidin-2-yloxy)-acetic acids and 2,3,4,5-tetrahydro-benzo[e][1,4]diazepin-1-ylmethyl}-benzoates; treating circulatory, inflammatory, and proliferative disorders
06/09/2005DE10351904A1 Verfahren zur Herstellung von cyclischen N-substituierten alpha-Iminocarbonsäure A process for the preparation of cyclic N-substituted alpha-iminocarboxylic acid
06/09/2005CA2545601A1 Quinazolinone compounds with reduced bioaccumulation
06/08/2005EP1538160A1 Substituted Isoquinolin-3-carboxyamides, their preparation and medical use
06/08/2005CN1623988A Biaryl sulfonamides and methods for using same
06/08/2005CN1205185C Nitrogenous cyclic compounds and pharmaceutical compositions containing the same
06/07/2005US6903216 Antiarrhythmic agents for the treatment and prophylaxis of atrial arrhythmias, atrial fibrillation (AF) or atrial flutter; potassium channel modulators, beta-blocker
06/07/2005US6903215 Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
06/07/2005US6903114 Carbocyclic alcohols such as 1,6-dinitronaphthalene-2,3-diol, used as catechol-O-methyltransferase inhibitors, for prophylaxis of Parkinson's disease
06/07/2005US6903107 Serine protease inhibitor
06/07/2005US6903094 As analgesic
06/02/2005WO2005049577A1 1-amino-isoquinoline derivatives for the treatment of diseases associated with inappropriate alk5
06/02/2005WO2005049576A1 Substitute isoquinolines useful in the treatment of diseases such as cancer and atherosclerosis
06/02/2005WO2005049023A1 Glyt1 transporter inhibitors
06/02/2005WO2005048810A2 Sigma-2 receptor radiotracers for imaging the proliferative status of solid tumors
06/02/2005US20050119495 For use as catalysts in asymmetric reactions, such as, hydrogenation, hydride transfer, allylic alkylation, hydrosilylation, hydroboration, hydrovinylation, hydroformylation, olefin metathesis, hydrocarboxylation
06/02/2005US20050119250 Amino-derivatives as novel inhibitors of histone deacetylase
06/02/2005US20050119227 Cyclic amine bace-1 inhibitors having a benzamide substituent
06/02/2005US20050119225 Phosphodiesterase 4 inhibitors, including N-substituted aniline and diphenylamine analogs
06/01/2005EP1534689A1 Novel carboxamide compounds having an mch-antagonistic effect, medicaments containing said compounds, and methods for the production thereof
06/01/2005EP1534273A2 Modulators of the glucocorticoid receptor and method
06/01/2005EP1254136A4 FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF
06/01/2005EP1115695B1 (r)-chiral halogenated 1-substitutedamino-(n+1)-alkanols useful for inhibiting cholesteryl ester transfer protein activity
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