Patents
Patents for C07D 205 - Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom (6,868)
07/1999
07/29/1999WO1999037612A1 Azetidinecarboxamide derivatives for treating cns disorders
07/28/1999EP0931060A1 Substituted n- (aminoiminomethyl or aminomethyl)phenyl]propyl amides
07/28/1999CN1223859A Process for preparation of pharmaceutical composition
07/27/1999US5929233 Cyclization for preparing halo-cephems
07/21/1999EP0930313A1 1-isothiazolidinone derivatives of azetidine-2-one, process for the preperation thereof and the use thereof
07/21/1999EP0759025B1 Amide derivatives and their therapeutic use
07/20/1999CA2256096A1 1-isothiazolidinone derivatives of azetidine-2-one, processes for the preparation thereof and use thereof
07/14/1999CN1222907A Azetidinone derivatives for treatment of atheroscleroses
07/14/1999CN1044069C Safety use of imidazolinone herbicides
07/08/1999WO1999019297A9 Synthesis of azetidine derivatives
07/06/1999US5919672 Adding racemic lactam to microorganism media containing buffer and solvent or enzyme with solvent and buffer to obtain an isomer, hydrolyzing the carboxylic ester of the compound to form an acid
06/1999
06/30/1999CN1043884C New substituted azacylobutanone, preparation method and medicinal use thereof
06/22/1999CA2256865A1 Synthesis of new .beta.-lactams
06/17/1999WO1999029667A1 Hydroxamic acid derivatives as matrix metalloprotease (mmp) inhibitors
06/15/1999US5912242 N-(4-substituted-benzyl)-2-aminolactam derivatives
05/1999
05/25/1999CA2154257C Spirocycloalkyl-substituted azetidinones useful as hypocholesterolemic agents
05/19/1999EP0915843A1 Azetidinone derivatives for the treatment of atheroscleroses
05/19/1999EP0752984B1 Process for the preparation of cyclohexyl-azetidinones
05/19/1999EP0720599B1 Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
05/19/1999EP0690851B1 Guanidine derivatives useful in therapy
05/19/1999CN1216972A Improved process for prodn. of enantiomerically-pure azetidine-2-carboxylic acid
05/18/1999US5905147 Halogenation and dehalogenation with cyclization to form penicillin rings or cephalosporins
05/06/1999EP0912755A1 The bioresolution of n-acylazetidine-2-carboxylic acids
05/04/1999US5900237 Catalytic antibodies which hydrolyze primary amides and methods for eliciting such antibodies
04/1999
04/28/1999EP0911327A1 Novel pyridonecarboxylic acid derivatives or their salts and antibacterial agent comprising the same as the active ingredient
04/28/1999EP0910573A1 New amino acid derivatives and their use as thrombin inhibitors
04/22/1999WO1999019297A1 Synthesis of azetidine derivatives
04/15/1999WO1999018074A1 Novel lactam metalloprotease inhibitors
04/15/1999WO1999018073A1 Azetidinone derivatives for the treatment of hcmv infections
04/15/1999WO1999018072A1 Azetidinone derivatives for the treatment of hcmv infections
04/15/1999WO1999018071A1 Azetidinone derivatives for the treatment of hcmv infections
04/15/1999CA2305679A1 Novel lactam metalloprotease inhibitors
04/14/1999CN1214043A Benzyl(idene)-lactam derivatives, their prepn. and their use as selective (ant) agaonists of 5-ht1A-and/or 5-ht1D receptors
04/14/1999CN1214039A Carbamoyloxy derivatives of mutiline and their use as antibacterials
04/07/1999EP0906312A1 Process for the preparation of carbapenem derivatives and intermediates thereof
04/07/1999EP0906278A1 3-hydroxy gamma-lactone based enantioselective synthesis of azetidinones
04/07/1999EP0906255A1 Improved process for the production of enantiomerically-pure azetidine-2-carboxylic acid
04/07/1999CN1213370A Substituted sulfonic acid N-[(aminoiminomethyl) phenylalkyl]-azaheterocyclamide compounds
04/06/1999US5892036 Process for the preparation of 2-bromo- and 2-nitroxy derivatives of 3-bromo- and 3,3-dibromo-4-oxo-azetidines
04/06/1999CA2077394C Substituted taxanes and pharmaceutical compositions containing them
04/06/1999CA1340485C Peptide analogs and their use as haptens to elicit catalytic antibodies
03/1999
03/25/1999WO1998050032A9 BETA-LACTAM INHIBITORS OF CoA-IT
03/24/1999EP0673432B1 Process for preparing clavulanic acid
03/24/1999EP0605637B1 Preparation of substituted isoserine esters using metal alkoxides and s-lactams
03/24/1999CN1211988A Process for preparation of 2-halomethyl-penems and their use for preparation of antibacterial penems
03/23/1999US5886175 Tetracycline antibiotics
03/23/1999US5886171 3-hydroxy gamma-lactone based enantioselective synthesis of azetidinones
03/23/1999US5885985 Antiinflammatory agents
03/23/1999US5885983 Inhibitors of microsomal triglyceride transfer protein and method
03/23/1999CA2033022C Safening imidazolinone herbicides
03/18/1999WO1999012931A1 Pyrrolopyrrolone derivatives as inhibitors of neutrophil elastase
03/18/1999CA2303249A1 Pyrrolopyrrolone derivatives as inhibitors of neutrophil elastase
03/10/1999EP0900199A1 Azetidinone derivatives for the treatment of atherosclerosis
03/09/1999US5880291 Process for producing optically active azetidine-2-carboxylic acid
03/09/1999US5879929 Enzymatic processes for the resolution of enantiomeric mixtures of lactams useful as intermediates in the preparation of taxanes
03/04/1999WO1999010323A1 Preparation of beta-methyl carbapenem intermediates
03/04/1999CA2298977A1 Preparation of beta-methyl carbapenem intermediates
02/1999
02/17/1999CN1042130C 4-oxo-azetidin-2-sulfonic-acid-amide and salt of same, preparation and application of same
02/09/1999US5869299 Using an enzyme system from streptomyces, particularly s. clavuligerus.
02/04/1999WO1999005093A1 Isocyanoalkyl carbonic acid derivatives, their conversion into secondary amidoalkyl carbonic acid derivatives by isocyanide-multicomponent reactions, as well as these secondary amidoalkyl carbonic acid derivatives.
02/04/1999WO1999005091A1 Novel compound having effect of promoting neuron differentiation
02/04/1999CA2297943A1 Novel compound having effect of promoting neuron differentiation
02/03/1999EP0894088A1 Substituted sulfonic acid n- (aminoiminomethyl)phenylalkyl]-azaheterocyclamide compounds
02/03/1999EP0894085A1 Benzyl(idene)-lactam derivatives, their preparation and their use as selective (ant)agonists of 5-ht1a- and/or 5-ht1d receptors
01/1999
01/28/1999WO1999003459A1 Kappa agonist anti-pruritic pharmaceutical formulations and method of treating pruritus therewith
01/28/1999DE19731893A1 New acylamino:alkyl-(thio)carbonate derivatives
01/28/1999CA2288828A1 Kappa agonist anti-pruritic pharmaceutical formulations and method of treating pruritus therewith
01/27/1999CN1206004A New substituted azetidinones and their use
01/26/1999US5863929 Anticoagulant agents
01/20/1999EP0675714B1 COMBINATION OF A CHOLESTEROL BIOSYNTHESIS INHIBITOR AND A $g(b)-LACTAM CHOLESTEROL ABSORPTION INHIBITOR
01/20/1999CN1205328A Sulfonylaminocarboxylic acids
01/14/1999WO1999001451A1 Azetidinylpropylpiperidine derivatives, intermediates and use as tachykinin antagonists
01/14/1999CA2294193A1 Azetidinylpropylpiperidine derivatives, intermediates and use as tachykinin antagonists
01/07/1999WO1999000356A1 Substituted n-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides
01/05/1999US5856556 Azetidinone derivatives, a process for their preparation and their use as intermediates in the preparation of carbapenem antibiotics
01/05/1999US5856473 Alkylation of the corresponding azetidinone compound with cinnamyl bromide compound; oxidation; reduction of ketone; debenzylation
01/05/1999US5856321 Preparation of carbapenems
01/05/1999US5856311 Derivatives of β-aminopropionic acid with a fungicidal activity
01/05/1999US5856307 Peptide derivatives as kininogenase inhibitors
12/1998
12/30/1998WO1998058934A1 Novel 2-(iminomethyl)amino-phenyl derivatives, preparation, application as medicines and compositions containing same
12/23/1998WO1998057932A1 New amidino derivatives and their use as thrombin inhibitors
12/23/1998WO1998057639A1 ALPHA 1aADRENERGIC RECEPTOR ANTAGONISTS
12/23/1998CA2294349A1 Alpha 1aadrenergic receptor antagonists
12/16/1998EP0884314A2 Metal alkoxides
12/16/1998EP0883620A1 Process for the preparation of 2-halomethyl-penems and their use for the preparation of antibacterial penems
12/15/1998CA1340273C 6-substituted thia-aza compounds
12/15/1998CA1340253C B-lactam antibiotics
12/09/1998CN1201459A Novel pyridonecarboxylic acid derivatives or their salts and antibacterial agent comprising same as active ingredient
12/08/1998US5847119 2-bromo-and derivatives of 3-bromo-and 3,3-dibromo-4-oxo-azetidines, processes for the preparation thereof and use thereof
12/08/1998US5847115 Azetidinone compound and process for preparation thereof
12/08/1998US5846966 Combinations of hydroxy-substituted azetidinone compounds and HMG CoA Reductase Inhibitors
12/01/1998US5843939 Derivatives of 3-bromo- and 3,3-dibromo-4-oxo-1-azetidines, processes for the preparation thereof and their use
11/1998
11/25/1998CN1199730A Production technology of 1-ethyl-2-aminomethyl tetrahydropyrrole and its intermediate product N-ethyl-a-pyrrolidone
11/24/1998US5840725 Substituted oximes, hydrazones and olefins as neurokinin antagonists
11/24/1998CA2108584C Substituted azetidinones as anti-inflammatory and antidegenerative agents
11/19/1998WO1998051298A1 Arylsubstituted piperazines useful in the treatement of benign prostatic hyperlasia
11/17/1998US5837717 Hydroxamic acid anesthetic compounds
11/12/1998WO1998050032A1 BETA-LACTAM INHIBITORS OF CoA-IT
11/12/1998WO1998050031A1 Inhibitors of protein isoprenyl transferases
11/12/1998WO1998050030A1 Inhibitors of protein isoprenyl transferases
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