Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
04/1999
04/01/1999WO1998051787A3 Gene construct encoding a heterologous prodrug-activating enzyme and a cell targeting moiety
04/01/1999WO1998048785A3 Allelic polygene diagnosis of reward deficiency syndrome and treatment
04/01/1999WO1998039464A8 Adenovirus vectors containing heterologous transcription regulatory elements and methods of using same
04/01/1999WO1998014592A3 Telomerase reverse transcriptase
04/01/1999CA2305350A1 Costimulating polypeptide of t cells, monoclonal antibodies, and the preparation and use thereof
04/01/1999CA2304642A1 Expression of endogenous genes by non-homologous recombination of a vector construct with cellular dna
04/01/1999CA2304268A1 Transgenic autologous t-cell therapy in humans, and related compositions and kits
04/01/1999CA2304259A1 Retroviral vectors comprising a functional splice donor site and a functional splice acceptor site
04/01/1999CA2304168A1 Methods and cell line useful for production of recombinant adeno-associated viruses
04/01/1999CA2304131A1 Method for gene transfer using bcl2 and compositions useful therein
04/01/1999CA2303663A1 Expression of genes in hematopoietic stem cells in hischaemic conditions
04/01/1999CA2303405A1 53bp2 complexes
04/01/1999CA2302936A1 Asthma associated factors as targets for treating atopic allergies including asthma and related disorders
04/01/1999CA2302778A1 Dna vaccination against cholesterol ester transfer protein in the treatment of atherosclerosis
04/01/1999CA2302339A1 Antigen presenting mesenchymal stem cells
04/01/1999CA2301957A1 Antisense oligonucleotides against thymidylate synthase
04/01/1999CA2246004A1 A kringle-related clone, hthbz47
03/1999
03/31/1999EP0905254A2 DNA vector associated with biocompatible low molecular weight polyethyleneimines
03/31/1999EP0905253A2 Adenoviral vector deleted of all E4-ORF except ORF6
03/31/1999EP0905250A1 The Chlamydia trachomatis Glutamyl-tRNAGln amidotransferase subunit ratA
03/31/1999EP0905249A2 Alcohol dehydrogenase
03/31/1999EP0905248A1 Staphylococcus aureus MurE protein and nucleic acids encoding it
03/31/1999EP0905247A2 MurF polynucleotides and polypeptides from Staphylococcus
03/31/1999EP0905246A1 Cloning of chicken anaemia DNA
03/31/1999EP0905245A1 Staphylococcal polypeptides Spo0J1
03/31/1999EP0905243A2 Polynucleotides from Staphylococcus aureus expressed in infected tissue
03/31/1999EP0905238A2 Pigrl-1, a member of immunoglobin gene superfamily
03/31/1999EP0905237A2 PIGR-2 A member of immunoglobulin gene superfamily
03/31/1999EP0905236A1 Transcription factor DP-1
03/31/1999EP0905233A2 Staphylococcus aureus trigger factor
03/31/1999EP0904786A1 Tumor vaccination by the use of antigen transduced autologous cells
03/31/1999EP0904405A2 Biomarkers for detection, diagnosis and prognosis of prostate cancer
03/31/1999EP0904394A1 Chicken embryo lethal orphan (celo) virus
03/31/1999EP0904392A1 Retroviral vectors
03/31/1999EP0904384A2 Tyrosine-phosphatase-related protein
03/31/1999EP0904382A1 Characterization and use of an isolated uridine diphospho-glucuronosyltransferase
03/31/1999EP0904380A2 Synthetic hiv genes
03/31/1999EP0904378A1 Hepatitis b monoclonal antibodies
03/31/1999EP0904374A1 Processed polypeptides with il-16 activity, process for preparing the same and their use
03/31/1999EP0904373A1 Targeted delivery of genes encoding interferon
03/31/1999EP0904372A2 Human phospholipase inhibitor
03/31/1999EP0904366A1 Apo-2li and apo-3 apoptosis polypeptides
03/31/1999EP0904352A1 Cell line
03/31/1999EP0904292A1 Growth differentiation factor-14
03/31/1999EP0904282A1 Novel cationic cholesteryl derivatives containing cyclic polar groups
03/31/1999EP0904281A1 STREPTOCOCCUS PNEUMONIAE HISTIDYL tRNA SYNTHETASE
03/31/1999EP0904280A1 STREPTOCOCCUS PNEUMONIAE ASPARTYL tRNA SYNTHETASE
03/31/1999EP0904278A1 Apoptosis inducing molecule ii
03/31/1999EP0904277A1 Compositions and methods for the treatment and diagnosis of cardiovascular disease
03/31/1999EP0904105A1 Novel compounds
03/31/1999EP0904104A1 Novel compounds
03/31/1999EP0904103A1 POLYNUCLEOTIDES AND POLYPEPTIDES OF THE GLUTAMYL tRNA SYNTHETASE FAMILY
03/31/1999EP0904100A1 Receptor ligand-facilitated delivery of biologically active molecules
03/31/1999EP0904090A1 Egg anti-inflammatory composition, method of isolation and use
03/31/1999EP0904031A1 Cationic polymer/lipid nucleic acid delivery vehicles
03/31/1999EP0903981A1 Design of novel highly efficient hiv based packaging systems for gene therapy
03/31/1999CN1212701A Oligonucleotide analogues
03/30/1999US5889175 Nucleic acids encoding HIV-1 trans-dominant mutants and their use to abrogate HIV-1 viral replication
03/30/1999US5889171 Genetic engineered polypeptide
03/30/1999US5889156 TNF deletion muteins
03/30/1999US5889145 Polynucleotides and polypeptides associated with benign prostatic hypertrophy
03/30/1999US5889143 Evaluation and treatment of patients with progressive immunosuppression
03/30/1999US5888981 Methods for regulating gene expression
03/30/1999US5888820 Retroviral vector capable of transducing the aldehyde dehydrogenase-1 gene and uses of said vector
03/30/1999US5888812 Myeloid cell leukemia associated gene MCL-1
03/30/1999US5888807 Devices for maintaining and growing human stem and/or hematopoietics cells
03/30/1999US5888771 Gene products as targets for the development of antibiotics.
03/30/1999US5888770 Spoiiie
03/30/1999US5888767 Method of using a conditionally replicating viral vector to express a gene
03/30/1999US5888751 Method for diagnosis and treating cancers, and methods for identifying pathogenic markers in a sample of normal cells
03/30/1999US5888732 Recombinational cloning using engineered recombination sites
03/30/1999US5888506 A detergent free polypeptide in the form of crystal structure or lyophilized or conjugated with polyoxyethylene glycol and contains less than 1 ng endotoxin per mg protein
03/30/1999US5888502 Recombinant retroviruses
03/30/1999CA2249058A1 Biologically tolerated low molecular weight polyethylenimines
03/25/1999WO1999014355A2 Highly affine nucleic acid molecules, production and application of same
03/25/1999WO1999014353A2 Intrabody-mediated control of immune reactions
03/25/1999WO1999014346A2 SENSE mRNA THERAPY
03/25/1999WO1999014334A1 Peptides derived from the attachment (g) protein of respiratory syncytial virus
03/25/1999WO1999014237A1 Macrophage derived chemokine (mdc) as an anti-viral agent for the treatment and prevention of lentivirus infections
03/25/1999WO1999014235A1 Persephin and related growth factors
03/25/1999WO1999014226A2 Bi- and tri-cyclic nucleoside, nucleotide and oligonucleotide analogues
03/25/1999WO1999013915A1 Method of delivering genes to antigen presenting cells of the skin
03/25/1999WO1999013905A1 Receptor-binding pocket mutants of influenza a virus hemagglutinin for use in targeted gene delivery
03/25/1999WO1999013898A1 EC-3, AN INHIBITOR OF α4β1 AND α4β7 INTEGRINS
03/25/1999WO1999013893A1 Peptide nucleic acids having antibacterial activity
03/25/1999WO1999013886A1 Multiple target hybridizing nucleic acids, their preparation, compositions, formulation, kits and applications
03/25/1999WO1999013719A1 Chemical modification of dna using peptide nucleic acid conjugates
03/25/1999WO1999004825A8 Methods and compositions for the diagnosis and treatment of neuropsychiatric disorders
03/25/1999WO1999000494A3 Cell activation process and reagents therefor
03/25/1999WO1998050067A9 Use or a secretion vector for fertility control by oral vaccination
03/25/1999WO1998048027A3 Materials and methods for treatment of retinal diseases
03/25/1999WO1998048009A3 Materials and methods for ribozyme treatment of retinal diseases
03/25/1999DE19741084A1 New library of chemically modified nucleic acid molecules
03/25/1999CA2304982A1 Sense mrna therapy
03/25/1999CA2304312A1 Multiple target hybridizing nucleic acids, their preparation, compositions, formulation, kits and applications
03/25/1999CA2304208A1 Intrabody-mediated control of immune reactions
03/25/1999CA2303908A1 Chemical modification of dna using peptide nucleic acid conjugates
03/25/1999CA2303397A1 Macrophage derived chemokine (mdc) as an anti-viral agent for the treatment and prevention of lentivirus infections
03/25/1999CA2303299A1 Bi- and tri-cyclic nucleoside, nucleotide and oligonucleotide analogues
03/25/1999CA2302316A1 Method of delivering genes to antigen presenting cells of the skin