Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
04/1999
04/08/1999WO1999016874A1 Nucleic acids coding for proteins capable of interacting with presenilins
04/08/1999WO1999016863A1 Generation of hematopoietic cells from multipotent neural stem cells
04/08/1999WO1999016790A1 Use of the tumour suppressor gene p33ing1 for modulation of p53 activity and in tumour diagnosis
04/08/1999WO1999016787A1 Cell death agonists
04/08/1999WO1999016783A1 Potent inhibitors of human 9-cis retinol dehydrogenase
04/08/1999WO1999016473A1 Lipid a 4' kinase
04/08/1999WO1999016458A1 Apolipoprotein a-i agonists and their use to treat dyslipidemic disorders
04/08/1999WO1999016409A2 Gene therapy approaches to supply apolipoprotein a-i agonists and their use to treat dyslipidemic disorders
04/08/1999WO1999009161A8 Pancreas-derived plasminogen activator inhibitor
04/08/1999WO1999006549A3 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN TESTIS AND OTHER TISSUES
04/08/1999WO1999006439A3 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN ENDODERM
04/08/1999WO1999005269A3 Transcriptional silencer protein nrf
04/08/1999WO1999004026A3 Lentiviral vectors
04/08/1999WO1999003987A3 Syncytial respiratory virus epitopes and antibodies comprising them, useful in diagnosis and therapy
04/08/1999WO1999003882A3 Human leukocyte calcium activated potassium channel polypeptide
04/08/1999WO1999003508A3 METHOD FOR TREATING VASCULAR PROLIFERATIVE DISEASES WITH p27 AND FUSIONS THEREOF
04/08/1999WO1998057664A9 Interleukin converting enzyme (ice) and central nervous system damage
04/08/1999WO1998056913A9 Smad6 and uses thereof
04/08/1999WO1998055638A9 Regulatory sequences capable of conferring expression of a heterologous dna sequence in endothelial cells in vivo and uses thereof
04/08/1999WO1998049321A8 Adenovirus-mediated intratumoral delivery of an angiogenesis antagonist for the treatment of tumors
04/08/1999CA2305809A1 Use of the tumour suppressor gene p33ing1 for modulation of p53 activity and in tumour diagnosis
04/08/1999CA2305781A1 Nucleic acids coding for proteins capable of interacting with presenilins
04/08/1999CA2305686A1 Sphingosine-1-phosphate lyase polypeptides, polynucleotides and modulating agents and methods of use therefor
04/08/1999CA2304814A1 Gene therapy approaches to supply apolipoprotein a-i agonists and their use to treat dyslipidemic disorders
04/08/1999CA2304007A1 Generation of hematopoietic cells from multipotent neural stem cells
04/08/1999CA2303401A1 Fusion proteins comprising an angiostatin moiety and their use in anti-tumor treatment
04/08/1999CA2290809A1 Lipid a 4' kinase
04/08/1999CA2246626A1 Rabies recombinant adenovirus
04/08/1999CA2245937A1 Novel histidine kinase
04/08/1999CA2213680A1 Nucleotide sequences and protein sequences
04/07/1999EP0906959A2 Aminopeptidase from Staphylococcus aureus
04/07/1999EP0906958A2 Staphylococcus peptidyl-tRNA hydrolase (Pth)
04/07/1999EP0906957A2 Lgt polypeptide
04/07/1999EP0906956A2 MurD from Streptococcus pneumoniae
04/07/1999EP0906955A2 FtsY
04/07/1999EP0906444A1 Genetically transfected human dendritic cells, their production and use, preferably as vaccines
04/07/1999EP0906443A1 Generating replicating molecules in vivo
04/07/1999EP0906442A1 Generation of viral transfectants using recombinant dna-derived nucleocapsid proteins
04/07/1999EP0906441A1 Antitumour cellular compositions expressing at least three transgenes
04/07/1999EP0906439A1 Polycistronic expression plasmid for tumor-rejection
04/07/1999EP0906423A1 Metastasis-associated antigen and antibodies thereto
04/07/1999EP0906422A1 Human cell death-associated protein
04/07/1999EP0906421A1 Enhanced efficacy of liposomal antisense delivery
04/07/1999EP0906330A1 STREPTOCOCCUS PNEUMONIAE ISOLEUCYL tRNA SYNTHETASE
04/07/1999EP0906328A1 Methods and compounds for curing diseases caused by mutations
04/07/1999EP0906124A2 Device and method for encapsulated gene therapy
04/07/1999EP0906123A1 OLIGONUCLEOTIDES TARGETED TO ANGIOTENSINOGEN mRNA
04/07/1999EP0906116A1 System and method for delivery of cytokines using encapsulated cytokine-secreting cells
04/07/1999EP0906110A1 Dna vaccine formulations
04/07/1999EP0754227A4 Chimeric complement inhibitor proteins
04/07/1999EP0689447B1 Cytopathic viruses for therapy and prophylaxis of neoplasia
04/07/1999CN1213004A Recombination leukocyte mesonium-2 adenovirus carrier and producing method
04/07/1999CN1212890A Compositions useful for transferring therapeutically active substances into target cell, and their use in gene therapy
04/07/1999CA2249715A1 Abc transporter
04/06/1999US5892071 Cationic transport reagents
04/06/1999US5891857 Characterized BRCA1 and BRCA2 proteins and screening and therapeutic methods based on characterized BRCA1 and BRCA2 proteins
04/06/1999US5891718 Positive feedback antibiotic controlled eukaryotic expression vectors with single transcription unit of first cistron coding for gene product, second cistron coding for antibiotic controlled activator; gene therapy and gene immunization
04/06/1999US5891704 Method to produce high levels of methioninase
04/06/1999US5891689 Heme-bearing microparticles for targeted delivery of drugs
04/06/1999US5891680 Dna molecule encoding an active il-12 fusion protein with at least two polypeptide monomers linked by heterologous polypeptide linker; stimulates ifn-alpha production, enhances antitumor immunity and cell mediated immunity
04/06/1999US5891678 Isolated polynucleotide encoding bacterial enzyme involved in mediating protein secretion; treatment of invasive infections and toxigenic diseases; antibiotic screening and development
04/06/1999US5891672 Polynucleotides encoding GTP cyclohydrolase II (ribA)
04/06/1999US5891670 Tetracycline resistance protein
04/06/1999US5891667 SpoIIIe polynucleotides
04/06/1999US5891638 A method of detecting alk-7 nucleic acid or polypeptide in a sample; and kits containing nucleic acid probes or antibodies.
04/06/1999US5891475 Non-liquid hydrophilic core, an external layer comprised of lipid compounds grafted on the core by covalent bonds. enhancing the activity of the polypeptide cellular mediator.
04/06/1999US5891468 Fusogenic liposome compositions and method
04/06/1999US5891459 Arginine, lysine and salts with nutrients for nitric oxide intermediates
04/06/1999US5891432 Membrane-bound cytokine compositions comprising GM=CSF and methods of modulating an immune response using same
04/06/1999US5891430 Diabetogene rad: a type II diabetes specific gene
04/01/1999WO1999015703A1 Inhibition of an fgf-binding protein using ribozymes
04/01/1999WO1999015687A1 Multicomponent polynucleotide complex for high efficiency cell transfection
04/01/1999WO1999015685A1 Methods and cell line useful for production of recombinant adeno-associated viruses
04/01/1999WO1999015684A2 Expression of genes in hematopoietic stem cells in hischaemic conditions
04/01/1999WO1999015683A1 Retroviral vectors comprising a functional splice donor site and a functional splice acceptor site
04/01/1999WO1999015677A1 Method for gene transfer using bcl2 and compositions useful therein
04/01/1999WO1999015671A1 Hepatitis b virus polypeptides
04/01/1999WO1999015657A2 53bp2 complexes
04/01/1999WO1999015656A2 Asthma associated factors as targets for treating atopic allergies including asthma and related disorders
04/01/1999WO1999015655A1 Dna vaccination against cholesterol ester transfer protein in the treatment of atherosclerosis
04/01/1999WO1999015650A1 Expression of endogenous genes by non-homologous recombination of a vector construct with cellular dna
04/01/1999WO1999015649A2 Composition and method for enhancing paracellular transport across cell layers
04/01/1999WO1999015648A1 Antisense oligonucleotides against thymidylate synthase
04/01/1999WO1999015635A1 Human ste20-like stress activated serine/threonine kinase
04/01/1999WO1999015630A1 Artificial viruses derived from papillomavirus, and their uses, in particular gene therapy
04/01/1999WO1999015626A1 Identification of hop-1 and uses thereof
04/01/1999WO1999015553A2 Costimulating t-cell polypeptide, monoclonal antibodies, their preparation and use
04/01/1999WO1999015544A1 NUCLEOTIDE AND AMINO ACID SEQUENCES OF THE brx GENE AND GENE PRODUCT, AND USES THEREOF
04/01/1999WO1999015206A1 Methods for preparing lipids/polynucleotide transfection complexes
04/01/1999WO1999015199A1 Antigen presenting mesenchymal stem cells
04/01/1999WO1999015190A1 Transgenic autologous t-cell therapy in humans, and related compositions and kits
04/01/1999WO1999002545A3 Antigen binding fragments, designated 4b5, that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
04/01/1999WO1999001551A3 Novel inhibitor of cellular proliferation
04/01/1999WO1998056370A3 Therapeutic nanospheres
04/01/1999WO1998055611A9 Neuregulin response element and uses therefor
04/01/1999WO1998054313A3 Dna methyltransferase genomic sequences and antisense oligonucleotides
04/01/1999WO1998054301A3 Transplants for myocardial scars and method and cellular preparations therefor
04/01/1999WO1998053075A3 Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
04/01/1999WO1998052615A9 Controlling immune response to specific antigens
04/01/1999WO1998052581A9 Vectors and methods for immunization or therapeutic protocols