Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
06/1999
06/17/1999WO1999000148A3 Method for treatment of spinal cord injuries in a mammal
06/17/1999CA2315216A1 Tgc method for inducting targeted somatic transgenesis
06/17/1999CA2314006A1 Method and composition to enhance the efficacy of a vaccine using chemokines
06/17/1999CA2313705A1 Restin and methods of use thereof
06/17/1999CA2313607A1 Antagonists of neuropilin receptor function and use thereof
06/17/1999CA2313390A1 Peptide antagonists of vascular endothelial growth factor
06/17/1999CA2313348A1 Soluble inhibitors of vascular endothelial growth factor and use thereof
06/17/1999CA2313251A1 Mutants of endostatin, "em 1" having anti-angiogenic activity and methods of use thereof
06/17/1999CA2312941A1 Peptide-based gemini compounds
06/17/1999CA2312890A1 Transfection particles
06/17/1999CA2312698A1 Compositions and methods for treatment of hepatitis c virus-associated diseases
06/17/1999CA2312697A1 Cadherin-like polypeptides, methods and compositions related thereto
06/17/1999CA2312484A1 Hepatitis c virus ns5b truncated protein and methods thereof to identify antiviral compounds
06/17/1999CA2312291A1 Novel vectors and genes exhibiting increased expression
06/17/1999CA2312287A1 Methods of producing anti-angiogenic proteins: endostatin, angiostatin or restin, using a pichia yeast expression system
06/17/1999CA2312006A1 Nucleic acid mediated rna tagging and rna revision
06/16/1999EP0922768A2 Oncogene or virus-driven expression systems
06/16/1999EP0922762A1 Drug binding protein
06/16/1999EP0922114A2 Catalytic nucleic acid and its medical use
06/16/1999EP0922110A2 Spatial and temporal control of gene expression using a heat shock protein promoter in combination with local heat
06/16/1999EP0922105A2 Infectious papillomavirus pseudoviral particles
06/16/1999EP0922102A1 Hepatocyte growth factor receptor agonists and uses thereof
06/16/1999EP0922100A2 Secreted proteins and polynucleotides encoding them
06/16/1999EP0922099A1 Fas ligand-like protein, its production and use
06/16/1999EP0922056A1 New fibrinogen binding protein originating from coagulase-negative staphylococcus
06/16/1999EP0922053A1 MAMMALIAN ADDITIONAL SEX COMBS (MAMMALIAN Asx) ACTS AS A TUMOR SUPPRESSOR
06/16/1999EP0921822A1 Animal model for transplantation
06/16/1999EP0921821A1 2-methoxyestradiol-induced apoptosis in cancer cells
06/16/1999EP0921820A1 Gene therapy for obesity
06/16/1999EP0921818A1 Therapeutic and diagnostic methods and compositions based on jagged/notch proteins and nucleic acids
06/16/1999EP0921816A1 Opsonin-enhanced cells, and methods of modulating an immune response to an antigen
06/16/1999EP0921805A1 Peptides recognized by melanoma-specific a1-, a2- and a3-restricted cytotoxic lymphocytes, and uses therefor
06/16/1999EP0669976B1 Screening method using transcription factor DP-1
06/15/1999US5912411 Mice transgenic for a tetracycline-inducible transcriptional activator
06/15/1999US5912335 A polynucleotide sequence that codes human 7-transmembrane receptor protein; treatment of infections, hiv, eating disorders, cancers, heart diseases, mental illnesses, huntington's disease, tourett's and parkinson's disease
06/15/1999US5912326 A recombinant polypeptide that is a receptor ligand for the oncogene, erbb; treatment of central nervous diseases, cardiac arrythmias, and amyotrophic lateral sclerosis
06/15/1999US5912300 Stabilizing anionic oligonucleotide by complexing(ionic bonding) it with a cationic lysine-serine copolymer, for delivering drugs or genetically active materials to cell interiors where they release smoothly
06/15/1999US5912236 Broad-spectrum tumor suppressor genes gene products and methods for tumor suppressor gene therapy
06/15/1999US5912173 Vector containing mutated interleukin-2r gamma nucleic acid when transfected into rodents, homologous recombination with x-chromosomes resulting in defective cells; animal models for severe combined immunodeficiency diseases
06/15/1999US5912170 Redirection of cellular immunity by protein-tyrosine kinase chimeras
06/15/1999US5912168 CD95 regulatory gene sequences
06/15/1999US5912159 An isolated human polypeptide which controls nitric oxide biosynthesis; diagnosis and therapy for urea cycle diseases, hypertension, hypotension, prostate cancer/ hyperplasia/ hypertrophy and kidney diseases
06/15/1999US5912149 A ribozyme molecule which functions in cis and trans, with a catalytic domain, an antisense domain and target recognition sequence containing self-cleavage site; gene therapy for hiv, hepatitis b virus and t cell leukemia viruses
06/15/1999US5912143 Polynucleotides encoding a human mage protein homolog
06/15/1999US5912130 Human Homolog of the rat G protein gamma-5 subunit
06/15/1999US5912123 Detection of the leptin receptor in reproductive organs and methods for regulating reproductive biology
06/15/1999US5912005 Methods of use of uncoated gel particles
06/15/1999US5911989 Antibodies
06/15/1999US5911983 Transduction of hematopoietic stem cells
06/10/1999WO1999028750A1 Frnk proteins in the treatment of tumor cells
06/10/1999WO1999028749A1 USES OF p27 IN PROSTATE CANCER
06/10/1999WO1999028489A2 Cell-specific retroviral vectors with antibody domains and method for the production thereof for selective gene transfer
06/10/1999WO1999028488A2 Pseudo-type retroviral vectors with modifiable surface capsid proteins
06/10/1999WO1999028486A1 Methods of isolating and using cd7+cd34-lin-hematopoietic cells
06/10/1999WO1999028469A1 Compositions and methods for inducing gene expression
06/10/1999WO1999028466A1 Compositions and methods of use of het
06/10/1999WO1999028459A1 Examination method, examination reagent and remedy for diseases caused by variation in lkb1 gene
06/10/1999WO1999028456A1 Splice variants for human 5-ht4 serotonin receptor and their applications, in particular for screening
06/10/1999WO1999028447A1 Human rnase h and compositions and uses thereof
06/10/1999WO1999028444A1 Differentiation of adipose stromal cells into osteoblasts and uses thereof
06/10/1999WO1999028440A1 Nucleic acid encoding mammalian ubr1
06/10/1999WO1999028439A2 Erythrovirus and its applications
06/10/1999WO1999028341A2 Maintenance of smooth muscle integrity by morphogenic proteins
06/10/1999WO1999027958A2 Hiv-1 tat, or derivatives thereof for prophylactic and therapeutic vaccination
06/10/1999WO1999027957A1 Vaccination and methods against multiple sclerosis using specific tcr vbeta peptides
06/10/1999WO1999027955A2 Treatment of established chronic infections and cancers
06/10/1999WO1999015684A3 Expression of genes in hematopoietic stem cells in hischaemic conditions
06/10/1999WO1999013073A3 Viral vector system capable of expressing an apoptosis-associated gene
06/10/1999WO1999013067A3 Hypoxia inducible promoter
06/10/1999WO1999007737A3 Lsr receptor, cloning and uses
06/10/1999WO1999006545A8 Composition and method for the detection of diseases associated with amyloid-like fibril or protein aggregate formation
06/10/1999DE19754103A1 New packaging cell line for E1-deleted adenovirus
06/10/1999CA2314423A1 Maintenance of smooth muscle integrity by morphogenic proteins
06/10/1999CA2313243A1 Nucleic acid encoding mammalian ubr1
06/10/1999CA2312847A1 Differentiation of adipose stromal cells into osteoblasts and uses thereof
06/10/1999CA2312002A1 Human rnase h and compositions and uses thereof
06/10/1999CA2311647A1 Hiv-1 tat, or derivatives thereof for prophylactic and therapeutic vaccination
06/10/1999CA2311414A1 Diagnostic method, diagnostic reagent and therapeutic preparation for diseases caused by variation in lkb1 gene
06/10/1999CA2310541A1 Splice variants for human 5-ht4 serotonin receptor and their applications, in particular for screening
06/09/1999EP0921197A2 Human disintegrin metalloprotease related to drosophila kuz gene
06/09/1999EP0921194A2 TRAILLK-2: a member of the TNF ligand family
06/09/1999EP0921193A1 Carrier: DNA complexes containing DNA encoding anti-angiogenic peptides and their use in gene therapy
06/09/1999EP0920843A1 Drug delivery system
06/09/1999EP0920534A1 MUTATIONS IN THE DIABETES SUSCEPTIBILITY GENES HEPATOCYTE NUCLEAR FACTOR (HNF) 1 ALPHA ($g(a)), HNF-1$g(b) AND HNF-4$g(a)
06/09/1999EP0920524A1 A short-shafted adenoviral fiber and its use
06/09/1999EP0920523A1 Hsv strain lacking functional icp27 and icp34.5 genes
06/09/1999EP0920518A1 Stimulus-inducible i (kappa)b kinase ikk] signalsome
06/09/1999EP0920515A1 A NOVEL HUMAN mRNA EDITING ENZYME
06/09/1999EP0920514A1 Targeting adenovirus with use of constrained peptide motifs
06/09/1999EP0920512A1 Dna molecule fragments encoding for cellular uptake of mycobacterium tuberculosis and uses thereof
06/09/1999EP0920507A2 Secreted proteins and polynucleotides encoding them
06/09/1999EP0920506A1 Human dbi/acbp-like protein
06/09/1999EP0920505A1 Mammalian cell surface antigens; related reagents
06/09/1999EP0920500A1 Human proteolipid
06/09/1999EP0920339A2 Gene delivery system
06/09/1999EP0920305A1 Identification of genes altered in multiple myeloma
06/08/1999US5910581 Polypeptides of glycosaminoglycan sulfotransferase originating from human and DNA coding for the polypeptides
06/08/1999US5910488 Plasmids suitable for gene therapy
06/08/1999US5910487 Cationic amphiphiles and plasmids for intracellular delivery of therapeutic molecules
06/08/1999US5910486 Introducing into a malignant mammalian cell a nucleic acid molecule encoding an antibody homologue intracellularly which binds to an oncoprotein on cell surface to kill the cell