Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
02/1999
02/04/1999WO1999005183A1 Cationic polymers, complexes associating said cationic polymers with therapeutically active substances comprising at least a negative charge, in particular nucleic acids, and their use in gene therapy
02/04/1999WO1999005171A1 NOVEL ESTROGEN RECEPTOR β AND ISOFORMS
02/04/1999WO1999005170A1 NOVEL ESTROGEN β RECEPTOR AND ISOFORMS
02/04/1999WO1999005161A1 HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA (PPARη) GENE REGULATORY SEQUENCES AND USES THEREFOR
02/04/1999WO1999004825A1 Methods and compositions for the diagnosis and treatment of neuropsychiatric disorders
02/04/1999WO1999004819A1 Liposomal compositions for the delivery of nucleic acid catalysts
02/04/1999WO1999004812A1 Nucleic acid based immunotherapy of chronic hepatitis b infection
02/04/1999WO1999004810A2 Use of mhc class ii ligands as adjuvant for vaccination and of lag-3 in cancer treatment
02/04/1999WO1999004806A1 Methods and compositions for inhibiting angiogenesis
02/04/1999WO1999004775A2 Method of treating dopaminergic and gaba-nergic disorders
02/04/1999WO1999004636A1 Evaluation of, delivery of, and use of agents to treat heart disorders
02/04/1999WO1998050079A3 Techniques and compositions for treating heart failure and ventricular remodeling by in vivo delivery of angiogenic transgenes
02/04/1999WO1998048821A3 Use of conantokins for producing analgesia or for neuroprotection
02/04/1999DE19733364A1 Verfahren zur Klonierung eines großen Virusgenoms Method for cloning a large viral genome
02/04/1999CA2732570A1 Use of mhc class ii ligands as adjuvant for vaccination and of lag-3 in cancer treatment
02/04/1999CA2305624A1 Recombinant lysostaphin analogs
02/04/1999CA2301166A1 Liposomal compositions for the delivery of nucleic acid catalysts
02/04/1999CA2298474A1 Methods and compositions for the diagnosis and treatment of neuropsychiatric disorders
02/04/1999CA2298410A1 Intracellular inhibitors of gq protein signaling
02/04/1999CA2298107A1 Use of transcription factor brn-3a
02/04/1999CA2298067A1 Conjugates of transporter peptides and nucleic acid analogs, and their use
02/04/1999CA2298053A1 Novel estrogen receptor .beta. and isoforms
02/04/1999CA2297907A1 Human estrogen receptor beta
02/04/1999CA2297487A1 Cationic polymers, complexes associating said cationic polymers with therapeutically active substances comprising at least a negative charge, in particular nucleic acids, and their use in gene therapy
02/04/1999CA2297410A1 Method of treating dopaminergic and gaba-nergic disorders
02/04/1999CA2297375A1 Ghrh expression system and methods of use
02/04/1999CA2297328A1 Evaluation of, delivery of, and use of agents to treat heart disorders
02/04/1999CA2296292A1 Secreted proteins encoded by human chromosome 13
02/04/1999CA2239267A1 Novel compounds
02/03/1999EP0894863A1 A YAK-1 related serine/threonine protein kinase-HTLAR33
02/03/1999EP0894862A2 Novel CysS
02/03/1999EP0894861A2 Glycogen phosphorylase from Streptococcus pneumoniae
02/03/1999EP0894859A2 Asparaginyl tRNA synthetase from Streptococcus pneumoniae
02/03/1999EP0894858A2 Prolyl tRNA synthetase from Streptococcus pneumoniae
02/03/1999EP0894857A2 SecA gene from Streptococcus pneumoniae
02/03/1999EP0894856A1 A human sMAD3 splice variant
02/03/1999EP0894855A2 Human I kappa B-beta transcription factor
02/03/1999EP0894854A2 A novel splicing variant of the epstein-barr virus-induced g-protein coupled receptor
02/03/1999EP0894853A1 Transcriptional silencer protein NRF, nucleic acid molecules encoding it and their use
02/03/1999EP0894806A1 Novel pheS
02/03/1999EP0894144A2 Diagnosing trinucleotide repeat diseases and genes involved therein
02/03/1999EP0894140A1 Allele suppression
02/03/1999EP0894139A1 Sensitization of her-2/neu overexpressing cancer cells to chemotherapy
02/03/1999EP0894137A1 Novel human myeloid terminal differentiation response gene
02/03/1999EP0894133A2 Neuropeptide y receptor y5 and nucleic acid sequence
02/03/1999EP0894132A2 Adam proteins and uses thereof
02/03/1999EP0894130A1 Modulators of tnf receptor associated factor (traf), their preparation and use
02/03/1999EP0894129A1 Short external guide sequences
02/03/1999EP0894006A1 POLYNUCLEOTIDES AND POLYPEPTIDES OF THE THREONYL tRNA SYNTHETASE FAMILY
02/03/1999EP0893950A1 Selective target cell activation by expression of a g protein-coupled receptor activated superiorly by synthetic ligand
02/03/1999EP0510186B1 Therapeutic uses of melanin
02/03/1999CN1207123A (-)-strand RNA virus vector having autonomously replicating activity repliation autonome
02/02/1999US5866755 Animals transgenic for a tetracycline-regulated transcriptional inhibitor
02/02/1999US5866699 Oligonucleotides with anti-MDR-1 gene activity
02/02/1999US5866696 Combination of vector and promoter can be used to introduce and express a human gene and correct a genetic defect in human cells resulting from malfunction of the mutant endogenous gene.
02/02/1999US5866693 Detecting mutations in the polynucleotides encoding the madr3 or madr4 and for detecting altered levels of the polypeptide in a host.
02/02/1999US5866553 Immune protection against infection
02/02/1999US5866552 Tranducing muscle cells
02/02/1999US5866551 Therapy for atherosclerosis
02/02/1999US5866550 Method of inhibiting replication of hyperproliferative cells using a nucleic acid encoding EIA
02/02/1999US5866546 Administering immunoregulator and cell proliferative agent
02/02/1999US5866535 Forming antibodies
02/02/1999US5866411 Genomic rna sequences
02/02/1999US5866390 Leucyl tRNA synthetase polynucleotides of streptococcus
02/02/1999US5866373 Polynucleotide encoding a human chemotactic protein
02/02/1999US5866370 Polynucleotides and polypeptides of the m29 aminopeptidase family, hereinafter referred to as ?aminopeptidase.?
02/02/1999US5866369 Amps
02/02/1999US5866366 gidB
02/02/1999US5866362 Protein aggregates obtained by a process comprising culturing a host cell that expresses a desired protein in a medium comprising an effective amount of cu++ and wherein the desired protein forms inclusion bodies in the host cell.
02/02/1999US5866340 Selective expression of desired genes in cells expressing oncoproteins
02/02/1999US5866332 Diagnosis and treatment of disease states related to proliferation, specifically myeloproliferative diseases and leukemias.
02/02/1999US5866329 Method and probe for detection of gene associated with liver neoplastic disease
02/02/1999US5866323 Cancer diagnosis prognosis and therapy based on mutation of receptors for transforming growth factor β and homologous growth controlling factors
02/02/1999US5865796 Gas driven gene delivery instrument
02/01/1999CA2238672A1 Seca
02/01/1999CA2238670A1 A novel smad3 splice variant as a target in chronic renal failure, atherosclerosis and fibrosis
01/1999
01/29/1999CA2239266A1 Novel histidine kinase
01/28/1999WO1999004265A2 Cancer associated nucleic acids and polypeptides
01/28/1999WO1999004040A1 Methods for diagnosis and treating cancers, and methods for identifying pathogenic markers in a sample of normal cells
01/28/1999WO1999004026A2 Lentiviral vectors
01/28/1999WO1999004025A1 Improvements in or relating to expression of nucleic acid sequences in cerebellar cells
01/28/1999WO1999004011A2 Hiv-1 group o antigens and uses thereof
01/28/1999WO1999004010A1 Nucleic acid vaccines encoding g protein of respiratory syncytial virus
01/28/1999WO1999004009A1 Method of dna vaccination using dna encoding antigen and encoding il6
01/28/1999WO1999004000A1 Adipocyte-specific protein homologs
01/28/1999WO1999003999A1 Methods and compositions for inhibiting the proinflammatory response
01/28/1999WO1999003998A1 Methods and compositions for tumor reduction
01/28/1999WO1999003992A1 Trail receptor
01/28/1999WO1999003987A2 Syncytial respiratory virus epitopes and antibodies comprising them, useful in diagnosis and therapy
01/28/1999WO1999003982A1 Interleukin-20
01/28/1999WO1999003980A1 Agm-derived stroma cells
01/28/1999WO1999003973A1 Cardiac muscle regeneration using mesenchymal stem cells
01/28/1999WO1999003890A1 Novel peptides and polypeptides useful for regenerating the nervous system
01/28/1999WO1999003889A1 Isolated dna encoding human calcium activated potassium channel
01/28/1999WO1999003886A1 Tropoelastin derivatives
01/28/1999WO1999003883A1 Compositions and methods based upon the tuberous sclerosis-1 (tsc1) gene and gene product
01/28/1999WO1999003882A2 Human leukocyte calcium activated potassium channel polypeptide
01/28/1999WO1999003508A2 METHOD FOR TREATING VASCULAR PROLIFERATIVE DISEASES WITH p27 AND FUSIONS THEREOF
01/28/1999WO1999003506A1 Remedies for solid tumor containing wilms' tumor gene (wt1) expression inhibitors
01/28/1999WO1999003505A1 Gene therapy vehicle comprising dermal sheath tissue