Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
05/2000
05/02/2000US6057437 Antisense nucleic acid compounds inhibiting vascular endothelial growth factor
05/02/2000US6057434 Polynucleotide which encodes a protein of specific amino acid sequence; for anticarcinogenic/antitumor agents, diagnostic and screening assays
05/02/2000US6057432 CysS
05/02/2000US6057300 Introducing expression vector comprising gene encoding p21 and expression vector comprising second gene encoding immunotherapeutic agent, genetic therapeutic, cytokine or prodrug converting enzyme to treat restenosis
05/02/2000US6057299 Isolated polynucleotide comprising prostate-specific enhancer which activates transcription of nucleotide sequence in human prostate cell, operably linked to polynucleotide sequence encoding heterologous polypeptide
05/02/2000US6057298 Administering to treat skin cancer
05/02/2000US6057158 Mammalian cell line having a recombinant plasmid with inverted terminal repeats, packaging sequences, and gene of interest and a helper adenovirus having loxp sequences and packaging sequences; for improved gene therapy
05/02/2000US6057155 Nucleic acid encoding a chimeric adenovirus fiber protein constrained by a non-preexisting loop; for efficient, direct entry of the nucleic acid-containing vector into cells for targeted gene therapy
05/02/2000US6057152 Recombinant viral vector system
05/02/2000US6057132 Nucleotide sequences encoding apoptosis associated Bbk protein
05/02/2000US6057129 Clock gene and methods of use thereof
05/02/2000US6057128 MU-1, member of the cytokine receptor family
05/02/2000US6057122 Antiangiogenic peptides polynucleotides encoding same and methods for inhibiting angiogenesis
05/02/2000US6056952 Selective elimination of T cells that recognize specific preselected targets
05/02/2000US6056938 Cationic lipids and the use thereof
05/02/2000CA2104014C Structural gene of pneumococcal protein
04/2000
04/27/2000WO2000023784A2 Method of detecting risk of type ii diabetes based on mutations found in carboxypeptidase e
04/27/2000WO2000023601A1 Delivery system for porcine somatotropin
04/27/2000WO2000023600A1 Materials and methods involving conditional aggregation domains
04/27/2000WO2000023599A2 Human proteins involved in endoplasmic reticulum protein degradation
04/27/2000WO2000023594A1 BIOACTIVE PEPTIDES AND PEPTIDE DERIVATIVES OF PARATHYROID HORMONE (PTH) AND PARATHYROID HORMONE-RELATED PEPTIDE (PTHrP)
04/27/2000WO2000023592A2 Minimal promoters and uses thereof
04/27/2000WO2000023587A2 Gene therapy of alzheimer's disease by delivery of an encoded apolipoprotein e
04/27/2000WO2000023584A1 Camel, an alternative translation product of the tumour antigen lage-1
04/27/2000WO2000023582A1 Gene transfer cell sheet and process for preparing the same
04/27/2000WO2000023575A1 Ups (ugc)
04/27/2000WO2000023572A1 Tnfr related gene 12
04/27/2000WO2000023569A1 Surfactant protein d for the prevention and diagnosis of pulmonary emphysema
04/27/2000WO2000023567A2 Promotion of self-renewal and improved gene transduction of hematopoietic stem cells by histone deacetylase inhibitors
04/27/2000WO2000023475A1 Intracellular c-terminal hdl-receptor domain
04/27/2000WO2000023467A1 birA
04/27/2000WO2000023464A2 Zinc finger binding domains for gnn
04/27/2000WO2000023116A1 Adeno-associated vectors for expression of factor viii by target cells
04/27/2000WO2000023115A1 TREATMENT OF TRAUMA (I.E. GRAFT REJECTION) WITH LIPOSOMES CONTAINING DNA ENCODING FOR CTLA4Ig OR FOR ANTI-CD40L
04/27/2000WO2000023112A1 Modulation of gene expression by combination therapy
04/27/2000WO2000023100A2 Genes and proteins predictive and therapeutic for renal disease and associated disorders
04/27/2000WO2000023088A2 Methods of administering adenoviral vectors
04/27/2000WO2000023084A1 Methods for stimulating the regeneration of inner ear cells
04/27/2000WO2000023083A1 Neuroprotective truncated bax polypeptides
04/27/2000WO2000022929A1 Gene transfer of human e2f-1 to inhibit vascular smooth muscle cell growth
04/27/2000WO2000006742A3 Chlamydia antigens and corresponding dna fragments and uses thereof
04/27/2000WO2000005407A3 DUPLICATIONS OF HUMAN CHROMOSOME 15q24-25 AND ANXIETY DISORDERS, DIAGNOSTIC METHODS FOR THEIR DETECTION
04/27/2000WO2000004141A3 Use of nucleic acid molecules as antiviral agents
04/27/2000WO2000003683A3 Liposomal encapsulated nucleic acid-complexes
04/27/2000WO1999067382A3 Angiopoietin-like growth factor sequences
04/27/2000WO1999065531A9 Polymers for delivery of nucleic acids
04/27/2000WO1999006544A8 Membrane-bound cytokine compositions and methods of modulating an immune response using same
04/27/2000DE19849044A1 New polycythemia rubra vera-related polypeptide useful for diagnosis and for developing therapeutic antibodies
04/27/2000DE19842863A1 Regulatorisches Protein aus humanen Keratinozyten Regulatory protein from human keratinocytes
04/27/2000CA2749553A1 Surfactant protein d for the prevention and diagnosis of pulmonary emphysema
04/27/2000CA2348156A1 Human proteins involved in endoplasmic reticulum protein degradation
04/27/2000CA2348068A1 Adeno-associated vectors for expression of factor viii by target cells
04/27/2000CA2347625A1 Genes and proteins predictive and therapeutic for renal disease and associated disorders
04/27/2000CA2347369A1 Minimal promoters and uses thereof
04/27/2000CA2347083A1 Methods of administering adenoviral vectors
04/27/2000CA2347080A1 Tnfr related gene 12
04/27/2000CA2347003A1 Modulation of gene expression by combination therapy
04/27/2000CA2346942A1 Camel, an alternative translation product of the tumour antigen lage-1
04/27/2000CA2346799A1 Delivery system for porcine somatotropin
04/27/2000CA2346152A1 Promotion of self-renewal and improved gene transduction of hematopoietic stem cells by histone deacetylase inhibitors
04/27/2000CA2343974A1 Materials and methods involving conditional aggregation domains
04/26/2000EP0995802A2 Method for the delivery of nucleic acids to cells in vitro or ex vivo
04/26/2000EP0995798A1 Transcription factor of MHC class II genes, substances capable of inhibiting this new transcription factor and medical uses of these substances
04/26/2000EP0995118A1 Chaperone fragments
04/26/2000EP0994959A1 Polymer-modified viruses
04/26/2000EP0994958A2 Selective regulation of adenovirus production
04/26/2000EP0994953A1 Expression system for production of therapeutic proteins
04/26/2000EP0994948A1 TGF$g(b) RII RECEPTOR NUCLEIC SEQUENCE, CODED PEPTIDE, AND USES
04/26/2000EP0994947A1 Mu-1, member of the cytokine receptor family
04/26/2000EP0994946A1 Coding sequence haplotypes of the human brca2 gene
04/26/2000EP0994945A2 Smad-interacting polypeptides and their use
04/26/2000EP0994899A2 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN ENDODERM
04/26/2000EP0994728A1 Recombinant antibodies specific for beta-amyloid ends, dna encoding and methods of use thereof
04/26/2000EP0994726A2 Compositions suitable for delivery of genes to epithelial cells
04/26/2000EP0994725A1 Thermodynamic adaptive phased array system for activating thermosensititve liposomes in targeted drug delivery
04/25/2000US6054570 Selective expression of desired genes in cells expressing oncoproteins
04/25/2000US6054560 Mitogen activated protein kinase, FRK
04/25/2000US6054559 Interleukin-1 receptor antagonist beta (IL-1raβ)
04/25/2000US6054558 Amino acid sequence of isolated polypeptide from gene upregulated in endothelial cells in response to shear stress; for treatment and diagnosis of atherosclerosis, hypertension, ischemia/reperfusion, restenosis, and arterial inflammation
04/25/2000US6054436 Regulated apoptosis
04/25/2000US6054312 Receptor-mediated gene delivery using bacteriophage vectors
04/25/2000US6054308 Arginase II
04/25/2000US6054288 Drug delivery to mammalian cells; obtaining cells from a mammal, transfecting cells with vector epressing therapy agent, culturing transfected cells, introducing transfected cells into a mammal
04/25/2000US6054273 Inhibitors of alternative alleles of genes as a basis for cancer therapeutic agents
04/25/2000US6054142 Biocompatible devices with foam scaffolds
04/22/2000CA2285749A1 Novel proteins from actinobacillus pleuropneumoniae
04/20/2000WO2000022430A2 Neisseria genomic sequences and methods of their use
04/20/2000WO2000022146A1 EXPRESSION AND SECRETION OF icIL-1 RECEPTOR ANTAGONIST TYPE II
04/20/2000WO2000022142A2 Cell signaling polypeptides and nucleic acids
04/20/2000WO2000022137A2 Selectively replicating viral vectors
04/20/2000WO2000022136A2 Recombinant e1a deleted adenoviral vectors
04/20/2000WO2000022127A1 Compositions and methods based upon p35, an isoform of p53
04/20/2000WO2000022124A2 Methods and compositions to induce antitumor response
04/20/2000WO2000022121A2 Ion channels, in particular vanilloid receptor-like (vr-l) receptor
04/20/2000WO2000022120A1 (mbp1) polypeptides capable of interacting with oncogenic mutants of the p53 protein
04/20/2000WO2000022118A2 Non-desensitizing ampa-receptors
04/20/2000WO2000022117A1 Tumor protein
04/20/2000WO2000022116A1 Human mdg1 gene (cbfawb10)
04/20/2000WO2000022113A1 ENZYMATIC SYNTHESIS OF ssDNA
04/20/2000WO2000022095A2 Method and apparatus for direct in vivo gene transfer by electrotransfection