Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
10/1999
10/26/1999US5972678 Animal 2-5A dependent RNases
10/26/1999US5972677 Allow for internal initiation of mrna cap-independent translation.
10/26/1999US5972676 Diagnosis and treatment of AUR-1 and/or AUR-2 related disorders
10/26/1999US5972674 May be used, for example, to identify antibodies and other agents that inhibit or activate signal transduction via the nf-.kappa.b cascade.
10/26/1999US5972673 Enzyme for phage resistance
10/26/1999US5972666 Assembly-deficient herpesvirus vaccine
10/26/1999US5972664 Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
10/26/1999US5972663 Microorganism strain that overexpresses a gene which encodes a protein directly suitable for secreting antibiotics, or other toxic substances, out of the cell, the strain also has deregulated metabolism for increased l-cysteine production
10/26/1999US5972659 Introducing into e. coli a heterologous plasmid expression vector coding for the tobacco mosaic virus protein coat and a pathogen's epitope, separating fusion protein and lowering ph to form a self-aggregated protein and hapten for vaccines
10/26/1999US5972658 DNA encoding lung growth factor variant
10/26/1999US5972654 The use of these sequences in the diagnosis, treatment, and prevention of developmental, reproductive, muscle, immunological, and neoplastic disorders.
10/26/1999US5972653 The use of these sequences in the diagnosis, prevention, and treatment of inflammation and disorders associated with cell proliferation and apoptosis.
10/26/1999US5972652 Polynucleotides encoding secreted proteins
10/26/1999US5972651 Polynucleotides and polypeptides of the fifty-four homologue family, (ffh); vectors and transformed host cells; ffh are components of protein secretory apparatus and their inhibition of function is deleterious to bacteria cells
10/26/1999US5972650 Can be used as vehicles for the delivery of nucleic acids that can serve as therapeutic agents and as part of vaccines designed to immunize people or animals against viral diseases.
10/26/1999US5972649 Polynucleotide sequence encoding human multiple endocrine neoplasia type 1 protein
10/26/1999US5972648 Hirudin analogs having val1-val2 of naturally-occurring hirudin substituted with ile1-ile2 are preferred for their high antithrombiin activity.
10/26/1999US5972646 Isolated nucleic acid molecule which codes for a 32 kDa protein having 11-cis retinol dehydrogenase activity, and which associates with P63, a portion of a retinol binding protein receptor
10/26/1999US5972645 Flea serine protease nucleic acid molecules
10/26/1999US5972644 Cyanobacterial and plant acetyl-CoA carboxylase
10/26/1999US5972636 ATP-dependent protease and use of inhibitors for same in the treatment of cachexia and muscle wasting
10/26/1999US5972633 Antibodies against heart muscle actin
10/26/1999US5972627 Method of purifying a population of cells enriched for dendritic and/or lymphoid progenitors and populations of cells obtained thereby
10/26/1999US5972623 Collagen-peptide assay method
10/26/1999US5972618 Detection of mutations in nucleic acids by chemical cleavage
10/26/1999US5972617 Oligonucleotides and methods for determining beer spoilage ability of lactic acid bacteria
10/26/1999US5972614 To screen patients for sensitivity to specific drugs. the present invention also relates to the isolation of naturally occurring gene targets for pharmaceutical development.
10/26/1999US5972613 Methods of nucleic acid isolation
10/26/1999US5972612 Analyzing nucleic acid sequences by measuring the binding interaction between two nucleic acid molecules, one nucleic acid is immobilized on a solid phase surface, binding affinity is determined by complementary annealing
10/26/1999US5972611 Hybridization carrier and a process for preparing the same
10/26/1999US5972610 Use of nucleic acid analogues in the inhibition of nucleic acid amplification
10/26/1999US5972609 Utrophin gene promotor
10/26/1999US5972607 Methods for nucleic acid amplification with thermostable ribonuclease H
10/26/1999US5972606 A polypeptide; treating osteoporosis, eating disorders, brain disorders, adult respiratory disease syndrome, huntington'sdisease, ulcers, cardiovascular disorders, parkinson's disease;
10/26/1999US5972605 Assays for regulators of mammalian telomerase expression
10/26/1999US5972602 Quantitative PCR-based method of gene detection
10/26/1999US5972601 Isolated polynucleotide molecules useful for analyzing alloantigen phenotypes, to peptides encoded by these molecules, and to the diagnostic and therapeutic uses thereof relating to the ?pen? human platelet polymorphism.
10/26/1999US5972600 Separation of active complexes
10/26/1999US5972599 High affinity nucleic acid ligands of cytokines
10/26/1999US5972597 Methods using modified vaccinia virus
10/26/1999US5972596 Nucleic acid constructs containing HIV genes with mutated inhibitory/instability regions and methods of using same
10/26/1999US5972352 Cloning of mite allergens
10/26/1999US5972349 Synthesis of polyribosylribitol phosphate oligosaccharides
10/26/1999US5972348 Nickel binding protein and its encoding dna isolated from helicobacter pylori; useful as vaccine, diagnostic, drug target, and therapy in itself
10/26/1999US5972338 ?tie? or ?tie? are acronyms, which stand for ?tyrosine kinase containing ig and egf homology domains?; present invention concerns novel human tie ligand homologues with powerful effects on vasculature; antitumor agents
10/26/1999US5972337 46 kilodalton human milk fat globule (HMFG) antigen, fragments and fusion protein
10/26/1999US5972336 Urease-based vaccine against helicobacter infection
10/26/1999US5972334 Vaccines for treatment of lymphoma and leukemia
10/26/1999US5972222 Separation of polynucleotide solution containing a counterion agent on wide pore, non-polar separation media which does not confine or release multivalent metal cations
10/26/1999US5972199 Electrochemical analyte sensors using thermostable peroxidase
10/26/1999CA2057536C Cloning and expression of borrelia lipoproteins
10/26/1999CA2011378C Achromobacter protease i gene and gene product thereof
10/26/1999CA1340805C Nucleotide sequence incoding plant ribosome inactivating protein
10/23/1999CA2268382A1 Overproduction of riboflavin in yeast
10/21/1999WO1999053319A2 High-density, miniaturized arrays and methods of manufacturing same
10/21/1999WO1999053310A1 Antigen
10/21/1999WO1999053304A1 Method for electroelution of a biological sample and implementing device
10/21/1999WO1999053103A1 Diagnosis of multiple sclerosis and other demyelinating diseases
10/21/1999WO1999053101A1 Identification of genetic targets for modulation by oligonucleotides and generation of oligonucleotides for gene modulation
10/21/1999WO1999053099A1 Recombinant proteins of treponema pallidum and their use for a syphilis vaccine
10/21/1999WO1999053098A1 Methods for identifying genetic determinants associated with modulation of test compound activity
10/21/1999WO1999053094A1 Method for in vivo detecting target protein gene by drug
10/21/1999WO1999053092A1 Diagnostic system and method for determining the presence of a genotoxic compound in a sample
10/21/1999WO1999053089A1 Recombinant adenovirus gene transfer vector
10/21/1999WO1999053085A2 Selective regulation of adenovirus production
10/21/1999WO1999053084A1 Preparation of recombinant adenovirus carrying a rep gene of adeno-associated virus
10/21/1999WO1999053083A1 Seed specific polycomb group gene and methods of use for same
10/21/1999WO1999053082A2 Hexose carrier proteins
10/21/1999WO1999053081A1 Method of producing plants which are tolerant or resistant to herbicides
10/21/1999WO1999053080A1 Novel constructs for controlled expression of recombinant proteins in prokaryotic cells
10/21/1999WO1999053079A1 Regulable gene expression in gram-positive bacteria
10/21/1999WO1999053078A2 Human protease and use of such protease for pharmaceutical applications and for reducing the allergenicity of non-human proteins
10/21/1999WO1999053077A1 Novel nep ii membrane metalloprotease and its use for screening inhibitors useful in therapy
10/21/1999WO1999053076A1 Tao protein kinases and methods of use therefor
10/21/1999WO1999053075A2 Cell cycle regulatory proteins cdc-16, dp-1, dp-2 and e2f from plants
10/21/1999WO1999053074A1 Enzyme derived from thermophilic organisms that functions as a chromosomal replicase, and preparation and uses thereof
10/21/1999WO1999053073A2 Interconversion of plant fatty acid desaturases and hydroxylases
10/21/1999WO1999053072A1 Starch r1 phosphorylation protein homologs
10/21/1999WO1999053071A1 Process for producing isoprenoid compounds by using microorganisms and method for detecting compounds having antibacterial or herbicidal activity
10/21/1999WO1999053070A1 Flowering locus t (ft) and genetically modified plants having modulated flower development
10/21/1999WO1999053069A2 Cell cycle regulatory proteins cdc2 and pitslre from plants
10/21/1999WO1999053068A2 Sucrose transporters from plants
10/21/1999WO1999053067A2 Seed-coat promoters, genes and gene products
10/21/1999WO1999053066A1 U4, a member of the hematopoietin receptor superfamily
10/21/1999WO1999053065A1 Improved methods for making hormone heterodimers
10/21/1999WO1999053064A2 Methods of delivering glp-1
10/21/1999WO1999053063A1 PEPTIDE LIGAND HAVING SPECIFIC AFFINITY FOR THE HIV1 RETROVIRUS p24 PROTEIN
10/21/1999WO1999053062A2 Isolated sh3 genes associated with myeloproliferative disorders and leukemia, and uses thereof
10/21/1999WO1999053061A2 Tumor associated nucleic acids and uses therefor
10/21/1999WO1999053060A2 Glaucoma therapeutics and diagnostics based on a novel human transcription factor
10/21/1999WO1999053059A1 Secretion of glycosylated proteins using a tissue plasminogen activator pro-sequence
10/21/1999WO1999053058A1 Vertebrate patched-2 protein
10/21/1999WO1999053057A1 Protein and gene participating in the differentiation of immortalized cells
10/21/1999WO1999053056A1 Novel protein and processes for producing the same
10/21/1999WO1999053055A2 Therapeutic agent for ngf
10/21/1999WO1999053054A1 Axor4 g-protein-coupled receptor
10/21/1999WO1999053053A1 Gene coding for heliomicine and use thereof
10/21/1999WO1999053052A2 Srebp-2-deficient cell lines
10/21/1999WO1999053051A2 5' ests and encoded human proteins
10/21/1999WO1999053050A1 Methods and means for obtaining modified phenotypes