Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210) |
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11/09/1999 | US5981736 One step device and process for concentration and purification of biological molecules |
11/09/1999 | US5981735 Method of plasmid DNA production and purification |
11/09/1999 | US5981732 Antisense oligonucleotides which target the expression of a g protein |
11/09/1999 | US5981731 Anticarcinogenic/antitumor/antiproliferative agents and diagnostic agents targeted against gene which codes for a protein kinase involved in signal transduction |
11/09/1999 | US5981730 RPS gene family, primers, probes, and detection methods |
11/09/1999 | US5981728 Complementary dna which codes for an enzyme involved in starch biosynthesis; for transgenic plants |
11/09/1999 | US5981727 Plant Group 2 promoters and uses thereof |
11/09/1999 | US5981724 DNA encoding CD40 ligand, a cytokine that binds CD40 |
11/09/1999 | US5981723 Dna which codes a nuclear protein in normal human cells that binds directly to the pocket of the underphosphorylated form of retinoblastoma protein; diagnosis of cancer/tumors; anticancer/antitumor agents |
11/09/1999 | US5981722 For stably transforming plants |
11/09/1999 | US5981717 Mammalian tolloid-like gene and protein |
11/09/1999 | US5981713 Antibody specific for an epitope of an interleukin-1 receptor antagonist; antiinflammatory/anticarcinogenic agents; prophylactic, diagnostic, therapeutic agents for autoimmune diseases |
11/09/1999 | US5981712 Antibody which binds to carboxyamido-triazole resistance protein; for detecting resistance to drug which prevents calcium influx in biological samples/cells |
11/09/1999 | US5981708 Rodent polypeptide which is an autocrine growth factor; for augmenting growth of hematopoeitic stem cells; for antitumor agents to control tumor cell growth |
11/09/1999 | US5981704 Kainate-binding, human CNS receptors of the EAA2 family |
11/09/1999 | US5981703 Receptor protein coded by nucleic acid and with glutamate binding activity; detection of compounds that function as plant growth regulators, herbicides, drugs |
11/09/1999 | US5981702 Polypeptide which is can bind to cyclin-dependent kinase; for diagnosis and therapy of cell proliferative defects in animals; antiproliferative agents |
11/09/1999 | US5981701 Tumor necrosis factor inhibitory protein and its purification |
11/09/1999 | US5981597 Differentiating agents for the treatment of inflammatory intestinal diseases |
11/09/1999 | US5981505 Compositions and methods for delivery of genetic material |
11/09/1999 | US5981501 Comlexing a plasmid with cationic lipids in a detergent solution to form a coated plasmid-lipid complex, contacting non-cationic lipids with the complex, removing detergent from solution to provide serum-stable plasmid-lipid particles |
11/09/1999 | US5981488 Polypeptide; antidiabetic agent |
11/09/1999 | US5981487 Method of inhibiting smooth muscle cell proliferation |
11/09/1999 | US5981482 Interleukin-1 receptor intracellular ligand proteins |
11/09/1999 | US5981480 Pantropic neurotrophic factors |
11/09/1999 | US5981299 Method of producing antibodies to an enzyme; immunizing cows with purified enzymes, recovering milk from cows, purifying antibodies; to alter the cholesterol composition of food; dietetics |
11/09/1999 | US5981281 Producing a targeted mutation in microorganism chromosome; transforming plasmid, allowing propagation, preferential screening, isolating and verifying transformant |
11/09/1999 | US5981280 Suppression of translation in bacteria by over expressing a messenger rna comprising a stop codon and nucleotide sequence formcold shock inducible gene complmentary to ribosomal rna, allowing annealing; bactericides |
11/09/1999 | US5981279 Compositions and methods to regulate calmodulin gene expression, and uses thereof for influencing cell growth and differentiation |
11/09/1999 | US5981277 Polypeptides and peptides, nucleic acids coding for them, and their use in the field of tumor therapy, inflammation or immunology |
11/09/1999 | US5981276 Vectors containing HIV packaging sequences, packaging defective HIV vectors, and uses thereof |
11/09/1999 | US5981275 Plasmid comprising heterologous genes linked to cytomegalo virus promoters and stably produces heterologous gene product; for delivery to cells |
11/09/1999 | US5981274 Genetically engineered viral genome with heterologous gene sequences which express functional gene product; for the encapsultion/packaging of virus genome; for antitumor agents, viricides and gene therapy for liver disorders |
11/09/1999 | US5981273 Composition comprising an endosomolytic agent for introducing nucleic acid complexes into higher eucaryotic cells |
11/09/1999 | US5981265 Controlling mitogen kinase polypeptide activity in a cell using transformation and transfection; for treating animals having cancer, inflammation, neurological disorders, autoimmune diseases, allergiies; anticarcinogenic agents |
11/09/1999 | US5981263 Nucleotide sequence coding a polypeptide extracellular matrix protein; for diagnosis, prevention, and treatment of vesicle trafficking, developmental, neoplastic and immunological defects; anticarcinogenic agents; antitumor agents |
11/09/1999 | US5981262 Nucleotide sequence coding a mammalian tyrosine kinase; for study of signal transduction pathway; for treatment of allergies and asthma; antiinflammatory agents |
11/09/1999 | US5981261 Pure culture for production of bacteriocin, for preparing foodstuffs such as sausages and cosmetics |
11/09/1999 | US5981259 CD4+ T-lymphocyte protease genes and inhibitors thereof |
11/09/1999 | US5981258 Composition of trans-dominant variants of viral proteins for obtaining an antiviral effect |
11/09/1999 | US5981257 For genetically engineered culture production of biodegradable, biocompatible thermoplastics |
11/09/1999 | US5981256 Recombinant stratum corneum chymotryptic enzyme (SCCE) |
11/09/1999 | US5981253 Enzyme isolation from akaline receptive microorganism; for processing of paper products, detergents |
11/09/1999 | US5981252 Enzyme for diagnosis of atherosclerosis; for screening enzyme inhibitors as therapy |
11/09/1999 | US5981251 PTP 1D: a novel protein tyrosine phosphatase |
11/09/1999 | US5981250 Nucleic acid sequence coding human tumor necrosis factor receptor associated protein; for diagnosis or treatment of disease associated with immune regulation; for drug screening; hybridization probes and primers |
11/09/1999 | US5981249 Polynucleotide which codes for an immunostable single-chain phosphorylating enzyme; for calibrators and controls in assays |
11/09/1999 | US5981248 Amino acid and nucleotide sequences coding for kinase involved in apoptosis; prevention of acidental cell death |
11/09/1999 | US5981247 Nucleotide sequence coding a modified viral polymerase; for diagnosing infection and monitoring disease over time; for screening possible enzyme inhibitors; viricides |
11/09/1999 | US5981246 Nucleic acids encoding EPH-like receptor protein tyrosine kinases |
11/09/1999 | US5981245 Polypeptide kinase coded by a nucleic acid sequence; antibody development; for modulating kinase receptor activation and detecting receptor ligands |
11/09/1999 | US5981243 Purified myceliophthora laccases and nucleic acids encoding same |
11/09/1999 | US5981236 Virus transfer vector with coding sequence for coat protein deleted and transacting factor gene deactivated; for methods of making the expression cassettes and using them to produce transfected plant cells |
11/09/1999 | US5981235 Treating a nucleic acid solution with a proteolytic enzyme to remove nucleases; adjust the ph, incubate solution with proteolytic enzyme until digestion is complete, lower ph and precipitate nucleic acids |
11/09/1999 | US5981231 Nucleotide sequence coding for polypeptide associated with human chemotactic activity; for diagnosis and therapy for gland defect; therapy for modulating bone marrow cell proliferation and differentiation |
11/09/1999 | US5981230 Polynucleotide encoding chemokine β-4 |
11/09/1999 | US5981229 For passive immune therapy; for diagnosis and prevention of grampositive bacterial infection; for prevention of infection by antibiotic resistant microoganisms |
11/09/1999 | US5981228 Mammalian ZPAs |
11/09/1999 | US5981227 Producing exogenous yeast polypeptides: insertion of a gene coding a protein heterologous to yeast into saccharomyces cervisiae strain genome, expression of gene |
11/09/1999 | US5981226 Vesicle transport associated proteins |
11/09/1999 | US5981225 Gene transfer vector, recombinant adenovirus particles containing the same, method for producing the same and method of use of the same |
11/09/1999 | US5981224 Bovine heat shock promoter and uses thereof |
11/09/1999 | US5981223 HDPXU17 encodes a novel 7-transmembrane receptor |
11/09/1999 | US5981222 Mammalian polynucleotide encoding protein factor; for disease prevention and treatment |
11/09/1999 | US5981220 Nucleotide sequences coding protein associated with skin differentiation; diagnostic assays for detecting bone and skin disorders; treatment of osteoporosis, bone fractures |
11/09/1999 | US5981219 Dna which codes for transport protein important in nitrogen metabolism; for plants that are richer in protein but have reduced content of carbohydrates and fats and thus increased nutritional and economic value; for herbicides |
11/09/1999 | US5981218 Isolated nucleic acid molecules useful as leukemia markers and in breast cancer prognosis and encoded polypeptides |
11/09/1999 | US5981217 Introducing and expressing dna sequence encoding mammalian polypeptide having three zinc finger domains in a host cell, detection and isolation of genes that encode factors involved in regulation of bone growth and differentiation |
11/09/1999 | US5981216 Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same |
11/09/1999 | US5981215 Human criptin growth factor |
11/09/1999 | US5981214 Amplifying and recovering mammalian gene product in cell culture; culturing continuous cell line, insertion of regulatory sequence, by recombination, into genome near target gene, transfer and expression of mammalian gene product |
11/09/1999 | US5981205 Nuclear Dbf2- related (Ndr) kinases |
11/09/1999 | US5981201 Methods of detection and treatment of breast cancer |
11/09/1999 | US5981200 A donor and an acceptor fluorescent protein moiety coupled together by a peptide linker; exhibit fluorescence resonance energy transfer which is eliminated upon cleavage of peptide linker; for enzymatic assays |
11/09/1999 | US5981195 Chimeric receptors and methods for identifying compounds active at metabotropic glutamate receptors |
11/09/1999 | US5981193 Human neuronal nicotinic acetylcholine receptor compositions and methods employing same |
11/09/1999 | US5981188 Method for identifying agents that modulate transcription of human cytomegalovirus polymerase |
11/09/1999 | US5981184 Kit for screening enzyme inhibitors including recombinant organism transformed with gene controlled by inducible promoter, an inducer, cations which impair metabolism and measuring device |
11/09/1999 | US5981182 Vector constructs for the selection and identification of open reading frames |
11/09/1999 | US5981181 DNA sequences with oligosaccharide transporter, plasmids bacteria and plants containing a transporter as well as a process for the preparation and transformation of yeast strains for identification of the transporter |
11/09/1999 | US5981179 Continuous amplification reaction |
11/09/1999 | US5981178 Diagnosing cystic fibrosis in vitro to determine if human subject is carrier of the genetic disorder; obtaining sample and analyzing genetic composition |
11/09/1999 | US5981177 Protein fusion method and constructs |
11/09/1999 | US5981174 Determining the metabolic phenotype of a human or a cell; removing dna sample from source, analyzing for mutants at specific genetic positions, classifying metabolic phenotype; for clinical trials and models of new drug interactions |
11/09/1999 | US5981173 Human urogenital virus dna; for diagnosis and for developing models for cancer of urogenital system |
11/09/1999 | US5981172 Probe for viral untranslated region; detecting viral nucleic acids; deveolping vaccines and antibodies to use as diagnostic tool in detecting presence of virus |
11/09/1999 | US5981171 Detecting dna sequences in heterogenous biological sample by hybridizing with probe, separating unhybridized sequences, detecting presence labeled target sequence; screening for oncogenes |
11/09/1999 | US5980958 Fungal food |
11/09/1999 | US5980910 Useful in coating polymeric medical materials to prevent colonization by coagulase-negative staphylococcal strains, in assays for the detection of such bacteria |
11/09/1999 | US5980909 Epitopic regions of pneumococcal surface protein A |
11/09/1999 | US5980907 Use in immunoprophylaxis |
11/09/1999 | US5980906 Live recombinant avian vaccine using an avian herpesvirus as vector |
11/09/1999 | US5980897 Treating mammals suffering from infections caused by gram-negative bacteria |
11/09/1999 | US5980896 Antibodies reactive with human carcinomas |
11/09/1999 | US5980891 Schizosaccharomyces-specific polypeptides |
11/09/1999 | US5980887 Methods for enhancing angiogenesis with endothelial progenitor cells |
11/09/1999 | US5980886 Recombinant vectors for reconstitution of liver |
11/09/1999 | US5980885 Growth factor-induced proliferation of neural precursor cells in vivo |
11/09/1999 | US5980713 Micro injector sample delivery system for charged molecules |
11/09/1999 | CA2136565C Polypeptide of protein p140 and dnas encoding it |