Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
11/1999
11/09/1999US5981736 One step device and process for concentration and purification of biological molecules
11/09/1999US5981735 Method of plasmid DNA production and purification
11/09/1999US5981732 Antisense oligonucleotides which target the expression of a g protein
11/09/1999US5981731 Anticarcinogenic/antitumor/antiproliferative agents and diagnostic agents targeted against gene which codes for a protein kinase involved in signal transduction
11/09/1999US5981730 RPS gene family, primers, probes, and detection methods
11/09/1999US5981728 Complementary dna which codes for an enzyme involved in starch biosynthesis; for transgenic plants
11/09/1999US5981727 Plant Group 2 promoters and uses thereof
11/09/1999US5981724 DNA encoding CD40 ligand, a cytokine that binds CD40
11/09/1999US5981723 Dna which codes a nuclear protein in normal human cells that binds directly to the pocket of the underphosphorylated form of retinoblastoma protein; diagnosis of cancer/tumors; anticancer/antitumor agents
11/09/1999US5981722 For stably transforming plants
11/09/1999US5981717 Mammalian tolloid-like gene and protein
11/09/1999US5981713 Antibody specific for an epitope of an interleukin-1 receptor antagonist; antiinflammatory/anticarcinogenic agents; prophylactic, diagnostic, therapeutic agents for autoimmune diseases
11/09/1999US5981712 Antibody which binds to carboxyamido-triazole resistance protein; for detecting resistance to drug which prevents calcium influx in biological samples/cells
11/09/1999US5981708 Rodent polypeptide which is an autocrine growth factor; for augmenting growth of hematopoeitic stem cells; for antitumor agents to control tumor cell growth
11/09/1999US5981704 Kainate-binding, human CNS receptors of the EAA2 family
11/09/1999US5981703 Receptor protein coded by nucleic acid and with glutamate binding activity; detection of compounds that function as plant growth regulators, herbicides, drugs
11/09/1999US5981702 Polypeptide which is can bind to cyclin-dependent kinase; for diagnosis and therapy of cell proliferative defects in animals; antiproliferative agents
11/09/1999US5981701 Tumor necrosis factor inhibitory protein and its purification
11/09/1999US5981597 Differentiating agents for the treatment of inflammatory intestinal diseases
11/09/1999US5981505 Compositions and methods for delivery of genetic material
11/09/1999US5981501 Comlexing a plasmid with cationic lipids in a detergent solution to form a coated plasmid-lipid complex, contacting non-cationic lipids with the complex, removing detergent from solution to provide serum-stable plasmid-lipid particles
11/09/1999US5981488 Polypeptide; antidiabetic agent
11/09/1999US5981487 Method of inhibiting smooth muscle cell proliferation
11/09/1999US5981482 Interleukin-1 receptor intracellular ligand proteins
11/09/1999US5981480 Pantropic neurotrophic factors
11/09/1999US5981299 Method of producing antibodies to an enzyme; immunizing cows with purified enzymes, recovering milk from cows, purifying antibodies; to alter the cholesterol composition of food; dietetics
11/09/1999US5981281 Producing a targeted mutation in microorganism chromosome; transforming plasmid, allowing propagation, preferential screening, isolating and verifying transformant
11/09/1999US5981280 Suppression of translation in bacteria by over expressing a messenger rna comprising a stop codon and nucleotide sequence formcold shock inducible gene complmentary to ribosomal rna, allowing annealing; bactericides
11/09/1999US5981279 Compositions and methods to regulate calmodulin gene expression, and uses thereof for influencing cell growth and differentiation
11/09/1999US5981277 Polypeptides and peptides, nucleic acids coding for them, and their use in the field of tumor therapy, inflammation or immunology
11/09/1999US5981276 Vectors containing HIV packaging sequences, packaging defective HIV vectors, and uses thereof
11/09/1999US5981275 Plasmid comprising heterologous genes linked to cytomegalo virus promoters and stably produces heterologous gene product; for delivery to cells
11/09/1999US5981274 Genetically engineered viral genome with heterologous gene sequences which express functional gene product; for the encapsultion/packaging of virus genome; for antitumor agents, viricides and gene therapy for liver disorders
11/09/1999US5981273 Composition comprising an endosomolytic agent for introducing nucleic acid complexes into higher eucaryotic cells
11/09/1999US5981265 Controlling mitogen kinase polypeptide activity in a cell using transformation and transfection; for treating animals having cancer, inflammation, neurological disorders, autoimmune diseases, allergiies; anticarcinogenic agents
11/09/1999US5981263 Nucleotide sequence coding a polypeptide extracellular matrix protein; for diagnosis, prevention, and treatment of vesicle trafficking, developmental, neoplastic and immunological defects; anticarcinogenic agents; antitumor agents
11/09/1999US5981262 Nucleotide sequence coding a mammalian tyrosine kinase; for study of signal transduction pathway; for treatment of allergies and asthma; antiinflammatory agents
11/09/1999US5981261 Pure culture for production of bacteriocin, for preparing foodstuffs such as sausages and cosmetics
11/09/1999US5981259 CD4+ T-lymphocyte protease genes and inhibitors thereof
11/09/1999US5981258 Composition of trans-dominant variants of viral proteins for obtaining an antiviral effect
11/09/1999US5981257 For genetically engineered culture production of biodegradable, biocompatible thermoplastics
11/09/1999US5981256 Recombinant stratum corneum chymotryptic enzyme (SCCE)
11/09/1999US5981253 Enzyme isolation from akaline receptive microorganism; for processing of paper products, detergents
11/09/1999US5981252 Enzyme for diagnosis of atherosclerosis; for screening enzyme inhibitors as therapy
11/09/1999US5981251 PTP 1D: a novel protein tyrosine phosphatase
11/09/1999US5981250 Nucleic acid sequence coding human tumor necrosis factor receptor associated protein; for diagnosis or treatment of disease associated with immune regulation; for drug screening; hybridization probes and primers
11/09/1999US5981249 Polynucleotide which codes for an immunostable single-chain phosphorylating enzyme; for calibrators and controls in assays
11/09/1999US5981248 Amino acid and nucleotide sequences coding for kinase involved in apoptosis; prevention of acidental cell death
11/09/1999US5981247 Nucleotide sequence coding a modified viral polymerase; for diagnosing infection and monitoring disease over time; for screening possible enzyme inhibitors; viricides
11/09/1999US5981246 Nucleic acids encoding EPH-like receptor protein tyrosine kinases
11/09/1999US5981245 Polypeptide kinase coded by a nucleic acid sequence; antibody development; for modulating kinase receptor activation and detecting receptor ligands
11/09/1999US5981243 Purified myceliophthora laccases and nucleic acids encoding same
11/09/1999US5981236 Virus transfer vector with coding sequence for coat protein deleted and transacting factor gene deactivated; for methods of making the expression cassettes and using them to produce transfected plant cells
11/09/1999US5981235 Treating a nucleic acid solution with a proteolytic enzyme to remove nucleases; adjust the ph, incubate solution with proteolytic enzyme until digestion is complete, lower ph and precipitate nucleic acids
11/09/1999US5981231 Nucleotide sequence coding for polypeptide associated with human chemotactic activity; for diagnosis and therapy for gland defect; therapy for modulating bone marrow cell proliferation and differentiation
11/09/1999US5981230 Polynucleotide encoding chemokine β-4
11/09/1999US5981229 For passive immune therapy; for diagnosis and prevention of grampositive bacterial infection; for prevention of infection by antibiotic resistant microoganisms
11/09/1999US5981228 Mammalian ZPAs
11/09/1999US5981227 Producing exogenous yeast polypeptides: insertion of a gene coding a protein heterologous to yeast into saccharomyces cervisiae strain genome, expression of gene
11/09/1999US5981226 Vesicle transport associated proteins
11/09/1999US5981225 Gene transfer vector, recombinant adenovirus particles containing the same, method for producing the same and method of use of the same
11/09/1999US5981224 Bovine heat shock promoter and uses thereof
11/09/1999US5981223 HDPXU17 encodes a novel 7-transmembrane receptor
11/09/1999US5981222 Mammalian polynucleotide encoding protein factor; for disease prevention and treatment
11/09/1999US5981220 Nucleotide sequences coding protein associated with skin differentiation; diagnostic assays for detecting bone and skin disorders; treatment of osteoporosis, bone fractures
11/09/1999US5981219 Dna which codes for transport protein important in nitrogen metabolism; for plants that are richer in protein but have reduced content of carbohydrates and fats and thus increased nutritional and economic value; for herbicides
11/09/1999US5981218 Isolated nucleic acid molecules useful as leukemia markers and in breast cancer prognosis and encoded polypeptides
11/09/1999US5981217 Introducing and expressing dna sequence encoding mammalian polypeptide having three zinc finger domains in a host cell, detection and isolation of genes that encode factors involved in regulation of bone growth and differentiation
11/09/1999US5981216 Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same
11/09/1999US5981215 Human criptin growth factor
11/09/1999US5981214 Amplifying and recovering mammalian gene product in cell culture; culturing continuous cell line, insertion of regulatory sequence, by recombination, into genome near target gene, transfer and expression of mammalian gene product
11/09/1999US5981205 Nuclear Dbf2- related (Ndr) kinases
11/09/1999US5981201 Methods of detection and treatment of breast cancer
11/09/1999US5981200 A donor and an acceptor fluorescent protein moiety coupled together by a peptide linker; exhibit fluorescence resonance energy transfer which is eliminated upon cleavage of peptide linker; for enzymatic assays
11/09/1999US5981195 Chimeric receptors and methods for identifying compounds active at metabotropic glutamate receptors
11/09/1999US5981193 Human neuronal nicotinic acetylcholine receptor compositions and methods employing same
11/09/1999US5981188 Method for identifying agents that modulate transcription of human cytomegalovirus polymerase
11/09/1999US5981184 Kit for screening enzyme inhibitors including recombinant organism transformed with gene controlled by inducible promoter, an inducer, cations which impair metabolism and measuring device
11/09/1999US5981182 Vector constructs for the selection and identification of open reading frames
11/09/1999US5981181 DNA sequences with oligosaccharide transporter, plasmids bacteria and plants containing a transporter as well as a process for the preparation and transformation of yeast strains for identification of the transporter
11/09/1999US5981179 Continuous amplification reaction
11/09/1999US5981178 Diagnosing cystic fibrosis in vitro to determine if human subject is carrier of the genetic disorder; obtaining sample and analyzing genetic composition
11/09/1999US5981177 Protein fusion method and constructs
11/09/1999US5981174 Determining the metabolic phenotype of a human or a cell; removing dna sample from source, analyzing for mutants at specific genetic positions, classifying metabolic phenotype; for clinical trials and models of new drug interactions
11/09/1999US5981173 Human urogenital virus dna; for diagnosis and for developing models for cancer of urogenital system
11/09/1999US5981172 Probe for viral untranslated region; detecting viral nucleic acids; deveolping vaccines and antibodies to use as diagnostic tool in detecting presence of virus
11/09/1999US5981171 Detecting dna sequences in heterogenous biological sample by hybridizing with probe, separating unhybridized sequences, detecting presence labeled target sequence; screening for oncogenes
11/09/1999US5980958 Fungal food
11/09/1999US5980910 Useful in coating polymeric medical materials to prevent colonization by coagulase-negative staphylococcal strains, in assays for the detection of such bacteria
11/09/1999US5980909 Epitopic regions of pneumococcal surface protein A
11/09/1999US5980907 Use in immunoprophylaxis
11/09/1999US5980906 Live recombinant avian vaccine using an avian herpesvirus as vector
11/09/1999US5980897 Treating mammals suffering from infections caused by gram-negative bacteria
11/09/1999US5980896 Antibodies reactive with human carcinomas
11/09/1999US5980891 Schizosaccharomyces-specific polypeptides
11/09/1999US5980887 Methods for enhancing angiogenesis with endothelial progenitor cells
11/09/1999US5980886 Recombinant vectors for reconstitution of liver
11/09/1999US5980885 Growth factor-induced proliferation of neural precursor cells in vivo
11/09/1999US5980713 Micro injector sample delivery system for charged molecules
11/09/1999CA2136565C Polypeptide of protein p140 and dnas encoding it