Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
10/1999
10/13/1999EP0948360A1 Novel lipid compounds and compositions containing same used for the transfer of at least an active substance, in particular a polynucleotide, in a target cell and therapeutic use
10/13/1999EP0948348A1 Manipulation of non-terminally differentiated cells using the notch pathway
10/13/1999EP0948323A1 Protease-activated receptor 3 and uses thereof
10/13/1999EP0948256A1 Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral rna
10/13/1999EP0948253A1 Isolated spinach rubisco large subunit n-methyltransferase
10/13/1999EP0850300B1 Method of modulating gene expression with reduced immunostimulatory response
10/13/1999EP0793502A4 Novel hedgehog-derived polypeptides
10/13/1999EP0770088A4 Novel cytokine designated lerk-5
10/13/1999EP0733121A4 Method of synthesizing a fluorescently labeled protein
10/13/1999EP0652955B1 Dna sequences for an amino acid transporter, plasmids, bacteria, yeasts and plants containing a transporter and their use
10/13/1999EP0618968B1 Tools for the diagnosis and treatment of alzheimer's disease
10/13/1999EP0603307B1 Monoclonal antibodies to putative hcv e2/ns1 proteins and methods for using same
10/13/1999EP0564592B1 Liver enriched transcription factor
10/13/1999EP0555435B1 DNA SEQUENCE ENCODING BOVINE $g(a)-LACTALBUMIN AND METHODS OF USE
10/13/1999CN1231702A Editing-based selectable plastid marker genes
10/13/1999CN1231699A Process for producing plants with female sterility
10/13/1999CN1231698A DNA-constructs comprising intergenic ribosomal DNA and methods to produce proteins using these DNA-constructs
10/13/1999CN1231697A In vivo protein synthesis method
10/13/1999CN1231696A Homocysteine desulphurase from the protozoan trichomonas vaginalis
10/13/1999CN1231695A HBV polyase, RNase H originated from HBV polyase, its preparation process and application in sieving antivirotic agent
10/13/1999CN1231694A Antitumor antisense sequences directed against R1 and R2 components of ribonucleotide reductase
10/13/1999CN1231673A Polynucleotide and its use for modulating a defence response in plants
10/13/1999CN1231580A Frozen confectionery products
10/13/1999CN1231339A Nucleic acid vaccine for cysticercosis co-contracted by human and pig
10/13/1999CN1231338A Gene engineering method for inhibiting formation of cotton toxin in cottonseed
10/13/1999CN1231337A Method for improving plant salt resistance by using transgenic technology
10/13/1999CN1231183A Method for preparing medicine for growing leukocyte by Chinese silkworm production gene engineering
10/13/1999CN1045621C Process for preparing immunoglobulin conjugates
10/13/1999CN1045620C Process for preparing DNA construction with preceding sequence of kluyveromyces X-factor directing heterologous polypeptide excretion
10/13/1999CN1045539C CDNA clones coding for polypeptides exhibiting human granulocyte macrophage and eosinophie cellular growth
10/12/1999US5965797 Bacterial genes
10/12/1999US5965796 Metal resistance sequences and transgenic plants
10/12/1999US5965795 Polynucleotide molecule from Haematococcus pluvialis encoding a polypeptide having a beta-C-4-oxygenase activity for biotechnological production of (3S, 3'S) astaxanthin and its specific expression in chromoplasts of higher plants
10/12/1999US5965794 Viral amplification of recombinant messenger RNA in transgenic plants
10/12/1999US5965793 Strong early seed-specific gene regulatory region
10/12/1999US5965792 Nucleic acids encoding metal uptake transporters and their uses
10/12/1999US5965791 Vector for introducing a gene into a plant, and methods for producing transgenic plants and multitudinously introducing genes into a plant using the vector
10/12/1999US5965790 SR-BI regulatory sequences and therapeutic methods of use
10/12/1999US5965789 Engineering protein posttranslational modification by PACE/furin in transgenic non-human mammals
10/12/1999US5965788 Transgenic non-human mammal comprising a rabbit WAP promoter
10/12/1999US5965787 HLA-DRBI peptides with specific binding affinity for HLA-DQ molecules: prevention and treatment of rheumatoid arthritis
10/12/1999US5965727 For selectable markers and promoters for plant tissue culture transformation
10/12/1999US5965726 Method of eliminating inhibitory/ instability regions of mRNA
10/12/1999US5965725 Polypeptides, and preparation and DNA encoding thereof
10/12/1999US5965724 GP 130 lacking the transmembrane domain
10/12/1999US5965723 DNA encoding epithelins
10/12/1999US5965722 Oligonucleotide with methylene(methylimino) linkages alternating with phosphorothioate or phosphodiester linkages; with increased nuclease resistance, stability, affinity for messenger rna; anticarcinogenic/antiarrhythmia agents
10/12/1999US5965720 With sequence complementary to messenger rna from a gene selected from the group consisting of c-myc, c-myb, c-fos, c-kit, ras and bcr/abl; antisense/anticarcinogenic agents
10/12/1999US5965711 A protein; anticarcinogenic/antiarthritic/antidiabetic agents; treatment of addison's and crohn's disease, multiple sclerosis, scleroderma, ulcers, respiratory disorders; fungicides, viricides, bactericides
10/12/1999US5965710 An immunoglobulin which binds human membrane-bound carcinoembryonic antigen; anticarcinogenic agent
10/12/1999US5965706 Anticarcinogenic agents; treatment and diagnosis of addison's disease, respiratory infections, crohn's disease, diabetes, multiple sclerosis, rheumatic diseases, anemia, antihistamines, antiallergens
10/12/1999US5965705 DNA and encoded protein which regulates cold and dehydration regulated genes
10/12/1999US5965704 Class two cytokine receptor-11
10/12/1999US5965703 Bcl-x/bcl-2 associated death polypeptide; used for regulating apoptosis in treating acquired immune deficiency syndrome and neurodegenerative diseases; antiischemic agents
10/12/1999US5965697 Disaggregated mutant human RANTES
10/12/1999US5965693 Isolated polynucleotides; diagnosis and treatment of autoimmune diseases, tissue rejection, allergies, acquired immune deficiency disorder, viricides, bactericides, fungicides and anticarcinogenic agents
10/12/1999US5965543 Senescence responsive transcriptional element
10/12/1999US5965542 Use of temperature to control the size of cationic liposome/plasmid DNA complexes
10/12/1999US5965541 Chimeric adenovirus coat protein of non-native amino acid sequence, which directs entry into cells of a vector more efficiently than a vector which is identical but with a wild-type adenovirus coat protein; ex vivo gene therapy
10/12/1999US5965535 Isolated human leukocyte antigen (hla) class ii-binding peptide and amino sequence encoding it; the peptides stimulate the activity and proliferation of cd4+ t lymphocytes
10/12/1999US5965455 Ryegrass pollen allergen
10/12/1999US5965444 Method for constructing transformant not having selective marker gene
10/12/1999US5965443 A mutant transposase enzyme having greater avidity for outside repeat sequences of donor dna; genetic engineering for introducing desired genetic changes to a nucleic acid
10/12/1999US5965441 HSV/AAV hybrid amplicon vectors
10/12/1999US5965440 Retroviral vector containing dna operatively linked with three different promters, a tetracyline regulatory unit under transcritpional control of the second promoter, an antisense orientated tetracycline response unit; gene therapy
10/12/1999US5965439 Host defense enhancement
10/12/1999US5965437 Method of screening a compound for hematopoietic activity
10/12/1999US5965435 Genetically engineered genes containing the herpes virus of turkeys gc gene, thymidine kinase region of marek's disease virus, infectious laryngotracheitis virus's open reading frame and ribonucleotide reductase genes; for vaccines
10/12/1999US5965434 Compounds contain cationic groups whose positive charge increases with decreasing ph; cationic liposomes fuse at ph's in the low end of the physiologic range; use in drug delivery systems; efficiency, less toxicity
10/12/1999US5965429 Streptomyces aureofaciens cell with a recombinant ctc 11 gene whose expression is enhanced compared to wild-type; for industrial biosynthesis of antibiotics
10/12/1999US5965427 Human RAD50 gene and methods of use thereof
10/12/1999US5965426 A protein; for effecient secretory production of heterologous proteins
10/12/1999US5965425 Expression of pace in host cells and methods of use thereof
10/12/1999US5965424 Mutating the immunoglobulin a protease gene to inactivate c-terminal helper sequence, transforming cells, culturing and expressing recombinant gene as inclusion bodies, isolating inclusion bodies, converting to active protease
10/12/1999US5965423 A polypeptide; diagnosis of cirrhosis, multiple sclerosis, gastrointestinal disorders, respiratory disorders, acquired immune defiency syndrome; antiarthritic/antiischemic/ antiallergens/ antiproliferactive agents
10/12/1999US5965422 Lysophospholipase produced from aspergillus by recombinant methods
10/12/1999US5965421 Human IRAK-2
10/12/1999US5965420 A protein which stimulates cell proliferation; treatment of bone loss due to osteoporosis; treat adult respiratory disease syndrome, parkinson'disease, huntington's disease; antiarthritic/anticarcinogenic agents; antiallergens
10/12/1999US5965419 Purified sulfotransferase
10/12/1999US5965418 A protein which catalyzes the oxidation of halide ions in the presence of hydrogen peroxide; microbiocides
10/12/1999US5965417 Arabidepsi thaliana proteins having Δ-5,7-sterol-Δ-7-reductase activity
10/12/1999US5965416 Arginyl tRNA synthetase from staphyloccus aureus
10/12/1999US5965415 Creating hybrid genes by transforming bacteria cells having a defective mismatch repair system or transitorily deactivated with two homologous dna sequences having mismatches, screening cells which have undergone stable recombination
10/12/1999US5965412 For phosphorolysis of kojibiose in presence of phosphoric acid and/or salt forming d-glucose and beta-d-glucose-1-phosphoric acid and/or salt; for transfer of glucosyl group to other saccharides producing oligosaccharides
10/12/1999US5965409 Kit containing at least three oligodeoxynucleotide primers with specific nucleotide sequences including restriction endonuclease recognition site; for isolating messenger rnas as complementary dna using polymerase amplification
10/12/1999US5965408 Amplifying heterologous, single stranded dna complementary to a gene with random oligonucleotide primers; prematurely terminating synthesis forming variable length strands; denaturing and reannealing strands; repeating cycle
10/12/1999US5965406 A genetically engineered molecule having a cell-binding domain, a translocation domain covalently bond to a toxin and an enzymatically active polypeptide; gene therapy, treatment of acquired immune deficieny syndrome
10/12/1999US5965405 Making recombinant antibodies containing the light and heavychain variable domains by transforming cells with an operon having a dna sequence which codes for only the variable domains, culturing and collecting expressed protein
10/12/1999US5965404 Adding nucleic acid/polycation complexes to animal cells in presence of ethylene glycol and/or glycerol; for simple and accurate transfection of cells for gene therapy and tumor vaccine production
10/12/1999US5965403 Nucleic acids encoding bone morphogenic protein-16 (BMP-16)
10/12/1999US5965400 DNA encoding a truncated pneumogoccal surface protein (PspA)
10/12/1999US5965397 Protein factor, cytokines, lymphokines, interferons, and interleukins, and colony stimulating factors; treatment of osteoporosis, stimulating or bone growth, regeneration of nerve and brain tissue, alzheimer/huntington disease's
10/12/1999US5965396 Human lymph node derived GTPase
10/12/1999US5965393 Method for enhancing foreign gene expression in baculovirus expression vector system
10/12/1999US5965392 A nucleic acid molecule; treating obesity or anorexia
10/12/1999US5965391 A structural gene positioned in front of a malate synthase gene which enables controlled expression of desired proteins in corynebacterium by inducing agents added to the medium; genetic engineering
10/12/1999US5965390 Protein L and hybrid proteins thereof
10/12/1999US5965389 Yeast which is transformed with dna construct of regulatory sequences and dna sequence coding glutamate decarboxylase isoform; for high level gene expression and industrial production of enzyme for screening and monitoring of diabetes
10/12/1999US5965388 Isolated polynucleotides; diagnosis and treatment autoimmune diseases, tissue rejection, allergies, acquired immune deficiency disease; viricides, bactericides and fungicides; anticarcinogenic agents
10/12/1999US5965387 Promoter