Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
10/1999
10/12/1999US5965386 Yeast strains and modified albumins
10/12/1999US5965384 Culturing aspergillus oryzae transformed with expression vector of regulatory sequences and dna sequences coding for humicola lanuginosa lipase, recovering lipase with different glycosylation and heat and/or proteolytic resistance
10/12/1999US5965383 Fibrin binding domain polypeptides and uses and methods of producing same
10/12/1999US5965382 Nucleic acid encoding secreted Mac-2 binding glycoprotein
10/12/1999US5965381 A mutant strain deficient in producing functional effector proteins; used for heterologous protein transfer into antigen presenting cells; treating infections by pathogens; inducing cellular immune response
10/12/1999US5965375 Diagnostic tests and kits for Clostridium difficile
10/12/1999US5965374 Glucan-specific assay
10/12/1999US5965373 Identifying enzyme inhibitors by combining a dimeric protein with a substrate, and a compound believed to be an inhibitor and determining activity of the protein on the substrate; diagnosis of epithelial cancer
10/12/1999US5965371 Targeting undesired antigens by intracellular expression of antibody capable of binding to the target; delivering a dna sequence with a promoter operably linked to the antibody; expressing antibody and binding antigen in cells of interest
10/12/1999US5965370 Antisense modulation of RhoG expression
10/12/1999US5965368 Determining protein-protein interactions by counterselection of two test proteins expressed in two separate nucleic acid libraries and measuring level of expression of reporter gene operably linked to a dna-binding-protein recognition sites
10/12/1999US5965367 Purified bradykinin B1 receptor
10/12/1999US5965365 A human growth factor receptor binding gene; treatment and diagnosis of smooth muscle disorders; antiproliferative/ anticarcinogenic/antitumor agents
10/12/1999US5965364 Method for selecting functional deoxyribonucleotide derivatives
10/12/1999US5965360 Diagnosis of metastatic cancer by the mts-1 gene
10/12/1999US5965359 Mixing cells from biological sample with detectable labeled complementary dna probe, detecting the presence of the probe that hybridizes with messenger rna for human platelet-derived growth factor receptor gene
10/12/1999US5965358 Providing an aliquot, producing charged fragments from the aliquot, detecting fragments by a detector which produces a signal corresponding to the mass-to-charge ratio of the detected fragments, evaluating purity using a standard signal
10/12/1999US5965355 Screening for grapevine leafroll-associcated virus 8 infection by binding the viral rna polypeptide with monoclonal antibody, detecting the bound antibody
10/12/1999US5965354 Obtaining biological sample with suspected antibody, reacting sample with type-specific antigens bound to solid support, allowing binding of antibodies to antigen, detecting with labeled immunoglobulin
10/12/1999US5965353 An epitope; for a diagnostic kit
10/12/1999US5965352 Methods for identifying pathways of drug action
10/12/1999US5965141 Epitopic regions of pneumococcal surface protein a
10/12/1999US5965140 Hybrid particle immunogens
10/12/1999US5965139 Chicken infectious anemia virus vaccine
10/12/1999US5965138 Recombinant chimeric virus and vaccine comprising a long viral genomic region from the herpes virus of turkeys and a short viral genomic region from marek's disease virus; immunizing birds
10/12/1999US5965136 Bone resorption assay
10/12/1999US5965135 HIV-1 virus isolates of a subtype and its differential diagnostics
10/12/1999US5965134 Immunogenic composition against Classical Swine Fever Virus (CSFV)
10/12/1999US5965133 Self-assembling multimeric nucleic acid constructs
10/12/1999US5965129 Purified cathepsin polypeptide and amino acid sequence or immunologically active fragments thereof; administering the novel protein with a pharmaceutical carrier to treat cancer
10/12/1999US5965124 Replication-competent recombinant viral vaccines and method of producing same
10/12/1999US5965123 Coated pesticidal agents, processes for their preparation and compositions containing them
10/12/1999US5965122 Use of interleukin-7 to stimulate proliferation of hematopoietic cell precursors
10/12/1999US5964726 Apparatus and method for efficient incorporation of molecules into cells
10/12/1999CA2096851C Tissue plasminogen activator substitution variant
10/12/1999CA1340787C Cdnas coding for members of the carcinoembryonic antigen family
10/12/1999CA1340781C Tumor specific monoclonal antibodies
10/07/1999WO1999050664A1 Compositions and methods for detecting ligand-dependent nuclear receptor and coactivator interactions
10/07/1999WO1999050657A1 Corticotropin releasing factor receptor 1-deficient mice
10/07/1999WO1999050462A1 Aptamer based bacterial inhibition systems (abbis)
10/07/1999WO1999050461A1 Therapeutic and diagnostic applications based on the role of the cxcr-4 gene in tumorigenesis
10/07/1999WO1999050457A1 Directed antisense libraries
10/07/1999WO1999050456A1 P53-regulated genes
10/07/1999WO1999050453A1 Method for searching steroid sulfatase inhibitors
10/07/1999WO1999050451A1 Polymorphism i: linkage of asthma to a locus on chromosome 2
10/07/1999WO1999050450A1 Polymorphism iii: linkage of atopy to a locus on chromosome 13
10/07/1999WO1999050448A2 Nucleic acid detection method
10/07/1999WO1999050436A1 Method of preparing polypeptides in cell-free system and device for its realization
10/07/1999WO1999050432A1 Inducible alphaviral gene expression system
10/07/1999WO1999050431A1 Novel retroviral constructs
10/07/1999WO1999050430A2 Modification of fatty acid composition in plants by expression of an aspergillus nidulans delta-9 coa desaturase
10/07/1999WO1999050429A1 Method of suppressing gene expression in plants
10/07/1999WO1999050428A2 Pathogen-inducible promoter
10/07/1999WO1999050427A2 Novel basal endosperm transfer cell layer (betl) specific genes
10/07/1999WO1999050426A1 Vectors for gene mutagenesis and gene discovery
10/07/1999WO1999050425A2 Regulated apoptosis using chemically induced dimerization of apoptosis factors
10/07/1999WO1999050423A2 Isochorismate synthase and its use for the induction of resistance in plants
10/07/1999WO1999050422A2 Method for reduction of fusel oils in alcoholic beverages and food products
10/07/1999WO1999050420A1 Method for increasing the phenoxy propionic acid hydroxylation rate
10/07/1999WO1999050419A2 A method for generating nonpathogenic, infectious pancreatic necrosis virus (ipnv) from synthetic rna transcripts
10/07/1999WO1999050418A1 Treatment and diagnosis of staphylococcal infections
10/07/1999WO1999050417A1 Novel sequence class of genes, corresponding proteins and the use of the same
10/07/1999WO1999050416A1 Tnf-related death ligand
10/07/1999WO1999050415A2 Protease-activated receptor par4 (zchemr2)
10/07/1999WO1999050414A1 Blk genes, gene products and uses thereof in apoptosis
10/07/1999WO1999050413A2 THERAPEUTIC APPLICATIONS OF MATURE FLINT (mFLINT) POLYPEPTIDES OR OPG3, A MEMBER OF THE TNF RECEPTOR SUPERFAMILY
10/07/1999WO1999050412A1 HUMAN p51 GENES AND GENE PRODUCTS THEREOF
10/07/1999WO1999050411A2 Tumour-specific expression control region and the use thereof
10/07/1999WO1999050410A1 Novel molecules expressed during muscle development and genetic sequences encoding the same
10/07/1999WO1999050409A1 Mixed-backbone oligonucleotides containing pops blocks to obtain reduced phosphorothioate content
10/07/1999WO1999050407A1 Monoclonal antibody against human telomerase catalytic subunit
10/07/1999WO1999050406A2 Growth differentiation factor-9 regulatory sequences and uses therefor
10/07/1999WO1999050405A1 Secreted proteins and polynucleotides encoding them
10/07/1999WO1999050404A2 Transgenic animals with inducible protein expression and methods of use
10/07/1999WO1999050403A2 Method and reagents for the treatment of diseases or conditions related to molecules involved in angiogenic responses
10/07/1999WO1999050402A1 Systematic identification of essential genes by in vitro transposon mutagenesis
10/07/1999WO1999050400A1 Amp deaminase
10/07/1999WO1999050396A1 Nek1-related protein kinase
10/07/1999WO1999050395A1 Serine-threonine protein kinase expressed in kidney
10/07/1999WO1999050392A1 Methods and compositions for eliciting an immune response to a telomerase antigen
10/07/1999WO1999050391A1 Stimulated monocyte derived cells, their preparation and uses
10/07/1999WO1999050389A1 Microbial strains and processes for the manufacture of biomaterials
10/07/1999WO1999050302A1 Chimeric protein containing an intramolecular chaperone-like sequence and its application to insulin production
10/07/1999WO1999050301A2 Epitopes in viral envelope proteins and specific antibodies directed against these epitopes: use for detection of hcv viral antigen in host tissue
10/07/1999WO1999050298A1 GFRα-X, A NOVEL GLIAL-DERIVED NEUROTROPHIC FACTOR RECEPTOR AND USES THEREFOR
10/07/1999WO1999050297A1 Nk cell activation inducing ligand (nail) dna and polypeptides, and use thereof
10/07/1999WO1999050296A1 Treatment and prevention of vascular disease
10/07/1999WO1999050294A1 Novel hemolytic active proteins and genes encoding the same
10/07/1999WO1999050293A1 Chimeric insecticidal protein and gene coding therefore
10/07/1999WO1999050292A1 Recombinant virus
10/07/1999WO1999050290A1 Para-poxvirus-coded vascular endothelial cell growth factor (ppv-vegf)
10/07/1999WO1999050288A2 Mammalian blood loss-induced gene, kd312
10/07/1999WO1999050285A2 Production methods and uses of a retrovirus
10/07/1999WO1999050281A2 Collagen peptides and uses thereof
10/07/1999WO1999050279A1 Antisense compositions for detecting and inhibiting telomerase reverse transcriptase
10/07/1999WO1999050278A1 Compositions and methods for the identification of lung tumor cells
10/07/1999WO1999050277A1 Circular, hairpin, circular/hairpin, lariat, and hairpin-lariat hammerhead ribozymes
10/07/1999WO1999049898A1 Progression elevated gene-3 and uses thereof
10/07/1999WO1999049892A2 Use of active p40 conjugates for nasal delivery
10/07/1999WO1999049888A2 Identification of bacterial avirulence genes and their products; vaccines and pharmaceutical compositions containing them