Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
12/1999
12/07/1999US5998137 To assess predisposition or susceptibility to a number of diseases: osteoporosis, atherosclerosis, cancer and immune disorders.
12/07/1999US5998136 Selection systems and methods for identifying genes and gene products involved in cell proliferation
12/07/1999US5998130 Non-A, non-B hepatitis virus genomic cDNA and antigen polypeptide
12/07/1999US5997943 Compound for a non-wettable coating, process for treatment of glass with the aid of the compound and products obtained
12/07/1999US5997882 Epitopic regions of pneumococcal surface protein A
12/07/1999US5997881 Method of making non-pyrogenic lipopolysaccharide or A
12/07/1999US5997878 Recombinant poxvirus-cytomegalovirus, compositions and uses
12/07/1999US5997872 Isolated nucleic acid molecule coding for tumor rejection antigen precursor MAGE-C1 and uses thereof
12/07/1999US5997870 Isolated peptides which bind to HLA-B44 Molecules
12/07/1999US5997867 Method of using humanized antibody against CD18
12/07/1999US5997865 Agonist antibodies against the flk2/flt3 receptor and uses thereof
12/07/1999US5997861 Antiviral supramolecules containing target-binding molecules and therapeutic molecules bound to spectrin
12/07/1999US5997860 Ex-vivo expansion of stem cells using combinations of interleukin-3 (IL-3) variants and other cytokines
12/07/1999US5997859 Gene encoding a conditionally lethal gene product which activates a purine- or pyrimidine-based prodrug into an agent that is cytotoxic to said metastatic carcinoma; and administering said prodrug to said patient
12/07/1999US5997857 Co-administration of interleukin-3 mutants with colony stimulating factors
12/07/1999US5997820 Integrally attached and operable multiple reaction vessels
12/07/1999US5997742 Method for performing polynucleotide separations using liquid chromatography
12/07/1999US5997269 Means for discovering microbes
12/07/1999CA2192687C Use of a bacterial component to enhance targeted delivery of polynucleotides to cells
12/07/1999CA2189581C Ice and ice-like compositions and methods of making same
12/07/1999CA2127188C Reagents and methods for coupled high temperature reverse transcription and polymerase chain reactions
12/07/1999CA2116764C Immunoreactive hepatitis c virus polypeptide compositions
12/07/1999CA2079714C Plants resistant to infection by pvx
12/07/1999CA2074943C Process for the enzymatic cleavage of recombinant proteins using iga proteases
12/07/1999CA2073288C Manipulation of gene copy number in bordetella
12/07/1999CA1340846E Expression of biologically active platelet derived growth factor analogs in eucaryotic cells
12/07/1999CA1340843C Selective amplification of target polynucleotide sequences
12/07/1999CA1340841C Cecropin-like polypeptides with activity against gram-positive and gram-negative bacteria
12/07/1999CA1340840C Diagnostic assays using nucleic acid probes
12/07/1999CA1340839C Proteins and process for preparing them, dna sequences, antibodies and uses thereof, posvirus, altered or infected cells, pharmaceutical compositions useful for the prevention of schistosomosis and uses thereof as an agent with a glutathion-s-transferase activity
12/07/1999CA1340838C Coccidiosis vacine
12/07/1999CA1340837C Expression and secretion of heterologous proteins by yarrowia lipolytica transformants
12/04/1999CA2273471A1 Dna detection by means of a strand reassociation complex
12/02/1999WO1999062315A2 Method for altering the activity of proteins of the pka signaling pathway
12/02/1999WO1999061918A1 Method and means for caries prevention and susceptibility detection
12/02/1999WO1999061916A1 Identification of broadly reactive dr restricted epitopes
12/02/1999WO1999061875A1 Sensing tapes for strain and/or temperature sensing
12/02/1999WO1999061814A1 Mechanical lock with a cam-driven locking pawl
12/02/1999WO1999061667A1 Primers for the detection of spore forming bacteria in paper products and paper manufacturing streams
12/02/1999WO1999061665A2 Solution hybridization of nucleic acids with antisense probes having modified backbones
12/02/1999WO1999061661A1 Method for amplifying at least a particular nucleotide sequence and primers used
12/02/1999WO1999061660A1 Demonstrating resistance to antibiotics in microorganisms
12/02/1999WO1999061658A1 Means and methods for monitoring non-nucleoside reverse transcriptase inhibitor antiretroviral therapy
12/02/1999WO1999061656A2 Agent and method for modulation of cell migration
12/02/1999WO1999061652A1 Carotenoid ketolase genes and gene products, production of ketocarotenoids and methods of modifying carotenoids using the genes
12/02/1999WO1999061651A2 Methods for producing a polypeptide by modifying the copy number of a gene
12/02/1999WO1999061649A1 Method for recovering soluble protein
12/02/1999WO1999061644A1 Hematopoietic progenitor cell gene transduction
12/02/1999WO1999061643A1 Method of preparing recombinant adeno-associated virus compositions by using an iodixananol gradient
12/02/1999WO1999061642A1 Recombinant aav vectors for gene therapy of hemophilia a
12/02/1999WO1999061641A1 Aav-vector production
12/02/1999WO1999061640A2 Aav derived vector
12/02/1999WO1999061639A2 Retroviral delivery system
12/02/1999WO1999061638A1 Chimeric adenoviral vectors
12/02/1999WO1999061636A1 Recombinant cytomegalovirus expression system targeting the immediate-early gene region
12/02/1999WO1999061635A2 Cotton cells, plants, and seeds genetically engineered to express insecticidal and fungicidal chitin binding proteins (lectins)
12/02/1999WO1999061634A1 Method of producing thy a-strains of vibrio cholerae, such strains and their use
12/02/1999WO1999061633A2 Method for the isolation of ccc plasmid dna
12/02/1999WO1999061632A1 A process for inhibiting expression of genes
12/02/1999WO1999061631A1 Dsrna-mediated regulation of gene expression in plants
12/02/1999WO1999061629A1 Cell separation device and separation method
12/02/1999WO1999061628A2 Novel nucleic acids and polypeptides related to a farnesyl-directed endopeptidase
12/02/1999WO1999061627A2 Mutant lactobacillus bulgaricus strains free from beta-galactoside activity
12/02/1999WO1999061626A2 Human hydrolase homologs: n-terminal asparagine amidohydrolase, glycosyl hydrolase, glucohydrolase, biotinidase, and n-acetylglucosamine 6-p deacetylase
12/02/1999WO1999061625A1 Mycobacterial n-acetyltransferases
12/02/1999WO1999061624A2 Polyhydroxyalkanoate biopolymer compositions
12/02/1999WO1999061623A2 Genetic method for producing riboflavin
12/02/1999WO1999061622A1 Xenobiotic related induction of gene expression
12/02/1999WO1999061621A1 Differential cytotoxicity of alternative forms of rotavirus nonstructural protein 4
12/02/1999WO1999061620A2 Neisseria meningitidis antigenic polypeptides, corresponding polynucleotides and protective antibodies
12/02/1999WO1999061619A2 Cell cycle genes, proteins and uses thereof
12/02/1999WO1999061618A2 Canine and feline immunoregulatory proteins, nucleic acid molecules, and uses thereof
12/02/1999WO1999061617A1 Interleukins-21 and 22
12/02/1999WO1999061616A2 DNA CODING FOR A Mg?2+/H+ OR Zn2+/H+¿ EXCHANGER AND TRANSGENIC PLANTS EXPRESSING SAME
12/02/1999WO1999061615A1 Kunitz domain polypeptide and materials and methods for making it
12/02/1999WO1999061614A2 Human socs proteins
12/02/1999WO1999061613A2 Interference with viral ires-mediated translation by a small yeast rna reveals critical rna-protein interactions
12/02/1999WO1999061612A1 Tumor suppressor
12/02/1999WO1999061611A1 Monomer protein with bone morphogenetic activity and medicinal agent containing the same for preventing and treating diseases of cartilage and bone
12/02/1999WO1999061610A2 TUMOUR SUPPRESSOR GENES OF THE p53 FAMILY
12/02/1999WO1999061609A1 Calmodulin related protein
12/02/1999WO1999061608A2 Polypeptides from creb binding protein and related protein p300 for use in transcriptional regulation
12/02/1999WO1999061607A2 Antisense oligonucleotides for treating proliferating cells
12/02/1999WO1999061605A2 System for reproducing and modulating stability and turnover of rna molecules
12/02/1999WO1999061604A2 A vector for gene trap, and a method for gene trapping by using the vector
12/02/1999WO1999061603A1 Rapid and simple process for isolation of circular nucleic acids
12/02/1999WO1999061602A1 Compositions and methods for the synthesis of fatty acids, their derivatives and downstream products
12/02/1999WO1999061601A2 Aav5 vector and uses thereof
12/02/1999WO1999061600A2 A method of modulating the efficiency of translation termination and degradation of aberrant mrna involving a surveillance complex comprising human upf1p, eucaryotic release factor 1 and eucaryotic release factor 3
12/02/1999WO1999061599A2 Recombinant narbonolide polyketide synthase
12/02/1999WO1999061598A2 Lentiviral vector compositions and methods of use
12/02/1999WO1999061597A2 Expression cassette for transformation comprising a modified viral sequence driven by a suitable promoter
12/02/1999WO1999061596A2 Novel post-transcriptional regulatory elements and uses thereof
12/02/1999WO1999061595A2 Adeno-associated viral vector-mediated expression of factor viii activity
12/02/1999WO1999061591A1 ENDO-β-N-ACETYLGLUCOSAMINIDASE GENE
12/02/1999WO1999061590A1 Methods and compositions useful for modulation of angiogenesis using tyrosine kinase src
12/02/1999WO1999061584A1 Compositions and methods for use in affecting hematopoietic stem cell populations in mammals
12/02/1999WO1999061582A2 Transgenic animals having modified hedgehog signal transduction and uses related thereto
12/02/1999WO1999061581A2 Sphingosine kinase, cloning, expression and methods of use
12/02/1999WO1999061580A2 Modification of cereal grain hardness via expression of puroindoline proteins