Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
12/1999
12/29/1999CA2331786A1 Exhaustive analysis of viral protein interactions by two-hybrid screens and selection of correctly folded viral interacting polypeptides
12/29/1999CA2331782A1 Tissue-specific and target rna-specific ribozymes
12/29/1999CA2331769A1 Prostate cancer-associated genes
12/29/1999CA2331385A1 Methods and reagents for producing transgenic monocot plants, comprisinga regulatable promoter controlling expression of a selectable marker gene in callus cells
12/29/1999CA2331326A1 Human glycoprotease-like proteins and dnas encoding these proteins
12/29/1999CA2331200A1 Olfactory receptors and their uses
12/29/1999CA2331152A1 Cell cycle regulating factor
12/29/1999CA2330937A1 Nucleic acid-coupled colorimetric analyte detectors
12/29/1999CA2330921A1 A screening system for agonists
12/29/1999CA2330731A1 Method for detecting, analyzing, and mapping rna transcripts
12/29/1999CA2330547A1 Novel hemopoietin receptor proteins
12/29/1999CA2330543A1 Methods for transferring the capability to produce a natural product into a suitable production host
12/29/1999CA2330542A1 Human arf-related proteins
12/29/1999CA2330526A1 Particles of hcv envelope proteins: use for vaccination
12/29/1999CA2330234A1 Method for detection of drug-selected mutations in the hiv protease gene
12/29/1999CA2330189A1 Bispecific antibodies for retargeting anticancer cytotoxic lymphocytes and hybriomas and monoclonal antibodies therefore
12/29/1999CA2330026A1 Compositions and methods for delivery of agents for altering neuronal growth, regeneration, and survival
12/29/1999CA2329939A1 Transgenetic non-human animal which comprises an inactive peg3 gene, and the use thereof
12/29/1999CA2329755A1 Synthetic somatostatin immunogen for growth promotion in farm animals
12/29/1999CA2329690A1 Methods to screen herbicidal compounds utilizing air synthetase from arabidopsis thaliana
12/29/1999CA2273408A1 Phytage formulation
12/28/1999US6008437 Use of anthocyanin genes to maintain male sterile plants
12/28/1999US6008436 Plant cells with a heterologous dna construct comprising a transcription cassette, in the 5' to 3' direction a promoter and dna encoding a nematode-inducible transmembrane pore protein; parasiticides
12/28/1999US6008435 Detecting cow, sheep and human prions in a sample and transgenic mice used for same
12/28/1999US6008434 Rodents with mutated endogenous growth differentiation factor-11 gene; animals exhibiting a phenotype of increased muscle tissue; animal food products with high muscle and protein content, reduced fat and cholesterol
12/28/1999US6008379 Useful as fluorescent dyes for labeling
12/28/1999US6008344 An oligonucleotide targeted to the coding region of the untranslated regions; therapy for alzheimer's disease
12/28/1999US6008343 Nucleotide sequence with oligonucleotide regions which are sufficiently complementary to hybridize to target rna sequences; gene therapy; viricides; fungicides; bactericides; for plants, humans, and animals
12/28/1999US6008340 Recombinant allergen, fragments thereof, corresponding recombinant DNA molecules, vectors and hosts containing the DNA molecules
12/28/1999US6008339 An oligonucleotide encoding a polypeptide, dor3, that induces dorsal and neural tissue development in vertebrates; therapy and diagnosis of alzheimer's/parkinson's/huntington's chorea, congenital diseases, anticarcinogenic/wound healing agents
12/28/1999US6008338 All-trans retinaldehyde binding protein, DNA encoding same, and antibodies thereto
12/28/1999US6008337 Polynucleotides encoding polypeptides; diagnosis and therpy for acquired immune disease syndrome, gout, addison's/crohn's diseases, adult respiratory distress syndrome, multiple sclerosis; antiarthritic/anticarcinogenic/antidiabetic agents
12/28/1999US6008336 Compacted nucleic acids and their delivery to cells
12/28/1999US6008326 A monospecific antigen protein of haemophililus influenzae; therapy for ear infections, meningitis, pneumonia, and oral diseases
12/28/1999US6008323 Transdominant negative proto-oncogene
12/28/1999US6008202 Comprising at least one cationic polypeptide salt; for transferring of nucleic acids or other macromolecule proteins into cells
12/28/1999US6008199 Continuously infusing an activated protein c for about 24 to 144 hours
12/28/1999US6008195 Antimicrobial peptides and methods of use
12/28/1999US6008194 Human preprotachykinin B
12/28/1999US6008051 A plasmid with halobacterium dna encoding a polypeptide capable of forming gas vesicles in non-floating escherichia cells; harvesting cells in fermentation and bioremediation as conferring bouyancy to hydrocarbon-degrading bacteria
12/28/1999US6008050 A polynucleotide encoding a polypeptide related to g protein coupled 7 transmembrane receptors; diagnosis/therapy of heart diseases, osteoporosis, anxiety, eating disorders, schizophrenia, ulcers, parkinson's/huntington's disease
12/28/1999US6008048 Antisense inhibition of EGR-1 expression
12/28/1999US6008046 Drug and pesticide screening
12/28/1999US6008042 A polynucleotide; diagnosis and therapy for stroke, septic shock, acquired immune deficiency syndrome, osteoporosis, antiarthritic/antiinflammatory/antiischemic agents, genetic disorders; alzheimer's/parkinson's diseases
12/28/1999US6008039 Polynucleotide encoding a novel purinergic P2U receptor
12/28/1999US6008038 Method and a circuit arrangement for the electropermeation of living cells
12/28/1999US6008035 System for the in vivo delivery and expression of heterologous genes in the bone marrow
12/28/1999US6008034 Isolated plant-derived dna sequence which codes for enzyme; for production of ?green note? compounds, volatile flavor and fragrance molecules from plant leaves, vegetables and fruits
12/28/1999US6008033 A herpes simplex virus-2 protease or diisopropylphosphate-liganded herpes simplex virus-2 protease in orthorhombic crystalline form; for computer models and screening for enzyme inhibitors as viricides
12/28/1999US6008032 Carboxymethyl cellulase from Thermotoga maritima
12/28/1999US6008030 A polynucleotide sequences encoding a protein; therapy and diagnosis of infections, respiratory and gastrointestinal disorders; toxic shock syndrome; antiarthritic and anticarcinogenic agents
12/28/1999US6008029 A nucleic acid which codes a protein obtained from a coprinus strain; for industrial use in lignin modification, paper strengthening, dye transfer inhibition in detergents, phenol polymerization, juice manufacture and waste water treatment
12/28/1999US6008026 A protein with improved performance and heat resistant; for use in liquefying starch; as an additive in laundry detergents, automatic dishwasher detergent and hard surface cleaning products; in food processing including baking aids
12/28/1999US6008025 A mutated polymerase having lower exonuclease activity and an extension rate of at least 30 bases/second at optimum temperature of about 75 degrees celsius while maintaining its residual activity at ph 8.8; improved dna amplification
12/28/1999US6008024 An protein which forms an immunological complex with a phosphorylated epitope of an antigen belonging to a paired helical filament-tau protein; diagnosis and therapy for alzheimer's disease
12/28/1999US6008023 Producing a fusion protein by transforming a thioredoxin reductase-deficient escherichia with a nucleotide molecule encoding an antibody or fragment; culturing and expressing the antibody; isolating antibody from the cytoplasm
12/28/1999US6008022 Human cytokine polypeptide
12/28/1999US6008018 ELL2, a new member of an ELL family of RNA polymerase II elongation factors
12/28/1999US6008017 Human cardiac/brain tolloid-like protein
12/28/1999US6008016 Spruce budworm antifreeze proteins, genes and methods of using same
12/28/1999US6008015 Glycine transporter
12/28/1999US6008014 Method of making lipid metabolic pathway compositions
12/28/1999US6008012 Human somatostatin-like receptor
12/28/1999US6008011 A nucleic acid; therapy for osteoporosis, rheumatic diseases; antiproliferative/anticarcinogenic/antiinflammatory agents; wound healing agents; immunosuppressants
12/28/1999US6007995 Antisense inhibition of TNFR1 expression
12/28/1999US6007991 Antisense oligonucleotides for mitogen-activated protein kinases as therapy for cancer
12/28/1999US6007990 A media containing selected amplifiers for amplification of target analytes and also contains labeled analyte specific materials which migrate through the media to target localized areas for visual detection; microorganism detection
12/28/1999US6007989 Methods of screening for compounds that derepress or increase telomerase activity
12/28/1999US6007988 A library of dna sequences which encode zinc finger polypeptide binding motifs for display on viral particles; the dna sequences having random allocation of amino acids; for producing zinc finger molecules
12/28/1999US6007985 Macromolecule delivery method and composition
12/28/1999US6007981 Modifying target cells making them sensative to a toxin; transforming cells with a nucleotide sequences encoding a receptor that binds cryia toxin of bacillus, culturing cells allowing receptor expression on cell surface
12/28/1999US6007821 Immunosuppression; organ transplants, insulin dependent diabetes
12/28/1999US6007807 Hybrid fusion cell comprising idiotypic antibody-expressing malignant b cell fused to b cell hybridoma expressing an antibody which is internalized on an antigen presenting cell
12/28/1999US6007806 Vaccinia virus vector comprising a heterologous dna sequence coding for essential region of t antigen, a protein specific to tumors caused by a papilloma virus
12/28/1999US6006470 Nematicidal proteins
12/28/1999CA2223142C Use of the indeterminate gametophyte gene for maize improvement
12/28/1999CA2151586C Novel bacillus thuringiensis strains active against lepidopteran and coleopteran pests
12/28/1999CA2143163C Peptides derived from a retrovirus of the hiv group, and their use
12/28/1999CA2068734C Mutants or variants of bacillus thuringiensis producing high yields of delta endotoxin
12/28/1999CA2054843C Novel strains of bacillus thuringiensis
12/28/1999CA1340866C Human c3b/c4b receptor (cr1)
12/28/1999CA1340864C Immobilized sequence-specific probes
12/28/1999CA1340863C Domain-modified constant region antibodies
12/28/1999CA1340862C Method of producing a human protein and dna-sequence for use when carrying out the method
12/28/1999CA1340861C Cysteine-depleted muteins of biologically active proteins
12/24/1999CA2276216A1 An artificial peptide capable of neutralizing the biological activity of interleukin-18
12/23/1999WO1999066324A2 A bioluminescence resonance energy transfer (bret) system and its use
12/23/1999WO1999066313A1 Reaction monitoring systems
12/23/1999WO1999066302A2 Recognition of protein coding regions in genomic dna sequences
12/23/1999WO1999066079A1 Detection of non-viral organisms with srp rna
12/23/1999WO1999066078A1 Denaturing gradient affinity electrophoresis and methods of use thereof
12/23/1999WO1999066076A1 Polymerase signaling assay
12/23/1999WO1999066075A2 Diagnostic method based on quantification of extramitochondrial dna
12/23/1999WO1999066073A1 METHOD FOR SCREENING Pax4 GENE EXPRESSION POTENTIATOR AND MEDICINAL COMPOSITIONS FOR POTENTIATING Pax4 GENE EXPRESSION
12/23/1999WO1999066072A2 Methods for treating a neurological disease by determining bche genotype
12/23/1999WO1999066071A1 Pcr primer constructs for use in an integrated signalling system
12/23/1999WO1999066067A1 Methods for testing biological network models
12/23/1999WO1999066065A2 Proteasomal activity
12/23/1999WO1999066061A1 Nucleic acid transfer phage
12/23/1999WO1999066060A1 Human mp52 gene promoter and method for exploring useful substance by using the same