Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
12/1999
12/21/1999US6004931 Method for inhibiting growth hormone action
12/21/1999US6004930 Administering gamma zein protein with phenylalanine amino acids removed; phenylketonuria treatment; eliminated codons
12/21/1999US6004929 Biologically active PDGF A-chain homodimers
12/21/1999US6004925 Polypeptide anticholesterol agents; cardiovascular disorders, restenosis, atherosclerosis
12/21/1999US6004815 Bacteria expressing nonsecreted cytolysin as intracellular microbial delivery vehicles to eukaryotic cells
12/21/1999US6004814 Antisense modulation of CD71 expression
12/21/1999US6004813 Il-6 activity inhibitor
12/21/1999US6004808 Promiscuous G-protein compositions and their use
12/21/1999US6004806 Optimized minizymes and miniribozymes and uses thereof
12/21/1999US6004804 Non-chimeric mutational vectors
12/21/1999US6004803 Genes encoding HSV1-TK containing a deletion of 5' cryptic promoter sites, vectors and cell lines
12/21/1999US6004802 Oral administration of pneumococcal antigens
12/21/1999US6004799 Recombinant live feline immunodeficiency virus and proviral DNA vaccines
12/21/1999US6004798 Retroviral envelopes having modified hypervariable polyproline regions
12/21/1999US6004797 Adenovirus helper-free recombinant AAV Virion production
12/21/1999US6004796 Amino acid sequence of enzyme effective in removal of arginine, phenylalanine or methionine from the n-terminal end of peptides in peptide or peptidomimetic synthesis
12/21/1999US6004794 Human serine protease
12/21/1999US6004792 Amino acid sequence of enzyme which controls intracellular lipids; for antiinflammatory/antiproliferative/ anticarcinogenic agents; diagnosis and prevention of autoimmune, gastrointestinal, and cardiovascular disorders
12/21/1999US6004790 Cyclomaltodextrin glucanotransferase variants
12/21/1999US6004789 Isolating gene from a producer organism and replacing codon for tryptophan at position 1174-1176 to an amino acid with reduced volume ratio; for enzyme which produces mainly (r)-(-)-phenylacetyl carbinol; for manufacture of ephedrine
12/21/1999US6004788 Enzyme kits and libraries
12/21/1999US6004787 Isolating macrolide polyketide biosynthetic gene, identifying enzymatic activities, mutating nucleotide sequence, transforming into a polyketide producing microorganism, culturing, and isolating product
12/21/1999US6004785 Transforming a filamentous fungus which is capable of being propagated in vitro in filamentous form with a vector comprising dna coding for a signal peptide and a polypeptide; for secretion of gene expression products
12/21/1999US6004780 Growth factor HTTER36
12/21/1999US6004779 Regulated gene expression in yeast
12/21/1999US6004777 Vectors having enhanced expression, and methods of making and uses thereof
12/21/1999US6004776 Transforming fungal cells with expression vector having approximately the same length as dna sequence which codes for ribosomal dna unit of fungus; for stable, high copy number integrants and improved protein production
12/21/1999US6004773 Method for producing L-lysine
12/21/1999US6004764 Screening methods for potential therapeutic agents which regulate the growth of m. tuberculosis; method for identifying genes of m. tuberculosis which are regulated by a sigma factor of m. tuberculosis
12/21/1999US6004752 Solid support with attached molecules
12/21/1999US6004750 Nucleic acid clamps
12/21/1999US6004748 Inhibiting the transcription of a gene used to treat arthritis and cancer
12/21/1999US6004747 Nucleic acid molecule for the detection and identification of salmonella serotypes comprising a single stranded dna fragment
12/21/1999US6004746 Interaction trap systems for detecting protein interactions
12/21/1999US6004557 Variants of human papillomavirus antigens
12/21/1999US6004556 Staphylococcus aureus RSBU-1
12/21/1999US6004553 Inhibitors of tumor necrosis factor receptor associated factor-(traf) mediated signal transduction; use in screening assays and as pharmaceuticals
12/21/1999US6004552 Administration of a monoclonal antibody capable of binding to a human cd40 antigen located on the surface of a human b cell, wherein the binding of the antibody to the cd40 antigen prevents the growth or differentiation of the b cell
12/21/1999US6004550 Intracellular expression of carboxypeptidase G2 in a nitrogen mustard prodrug system
12/21/1999US6004548 Polypeptides possessing primary structural conformation and biological properties of mammalian pluripotent granulocyte colony stimulating factor wherein at least one cysteine residue at positions 17,36,42,64,74 is replaced by alanine
12/21/1999US6004535 Methods of imaging neoplastic disease and of detecting and quantifying MN protein/polypeptide using MN-specific antibodies
12/21/1999US6004513 Automatic device for nucleic acid sequence detection employing amplification probes
12/21/1999US6004354 IceA gene and related methods
12/21/1999CA2230245C Buchloe dactyloides extracts having insecticidal properties
12/21/1999CA2197075C Method of gene therapy using dna vectors without selection marker gene
12/21/1999CA2126514C Cyclodextrin glycosyltransferases for producing y-cyclodextrins
12/21/1999CA2122135C Recombinant core-streptavidin
12/21/1999CA2092708C Cationic charge modified microporous membranes
12/21/1999CA2072891C Pseudomonas exotoxin fusion proteins having carboxyl alterations with increased cytotoxicity
12/21/1999CA2065287C New hcv isolates
12/21/1999CA2058872C Recombinant iga protease
12/21/1999CA2022942C Method of assessing sensitivity of hiv to zidovudine
12/21/1999CA1340858C Recombinant and native group b eimeria tenella immunogens useful as coccidiosis vaccines
12/21/1999CA1340857C Synthetic plasmid transformant, feline interferon gene and method for producing feline interferon
12/21/1999CA1340855C Neurite-promoting factor and process for the manufacture thereof
12/21/1999CA1340853C Purification of recombinant interleukin-2
12/19/1999CA2273059A1 Method of dwarfing plants
12/17/1999CA2272131A1 Mobile genetic elements as tools for genetic modification of l.delbrueckii or l.helveticus
12/17/1999CA2235420A1 Antisense oligonucleotides for treating or preventing atopic diseases and neoplastic cell proliferation
12/16/1999WO1999064866A1 A method of identifying ligands to rna polymerase sigma 70 subunit
12/16/1999WO1999064633A1 Herpes simplex virus origin binding protein n-terminal truncation (obp-nt)
12/16/1999WO1999064632A1 Restriction enzyme gene discovery method
12/16/1999WO1999064629A1 Acrp30r2, a homolog of acrp30 (30 kd adipocyte complement-related protein)
12/16/1999WO1999064626A2 Probes used for genetic profiling
12/16/1999WO1999064625A2 Methods and kits for discovery of rna-binding compounds
12/16/1999WO1999064624A2 Method of generating nucleic acid hybrids for mutation analysis
12/16/1999WO1999064623A1 Support for the parallel identification and establishment of transcription profiles of polynucleic acids
12/16/1999WO1999064619A2 Novel mannanases
12/16/1999WO1999064618A1 Vitamin c production in microorganisms and plants
12/16/1999WO1999064616A2 Polyunsaturated fatty acids in plants
12/16/1999WO1999064615A1 Formulations for electroporation
12/16/1999WO1999064614A2 Polyunsaturated fatty acids in plants
12/16/1999WO1999064613A1 D-ribulose-5-phosphate-3-epimerase nematode response gene
12/16/1999WO1999064612A1 Enhanced storage organ production in plants
12/16/1999WO1999064611A1 Mass production method of antimicrobial peptide and dna construct and expression system thereof
12/16/1999WO1999064610A1 ZmpB, A NEW DETERMINANT OF VIRULENCE FOR STREPTOCOCCUS PNEUMONIAE, VACCINE DERIVED THEREFROM AND USES THEREOF
12/16/1999WO1999064609A1 New human carboxypeptidase inhibitor
12/16/1999WO1999064608A1 Corin, a serine protease
12/16/1999WO1999064607A1 Industrial method for producing heterologous proteins in e.coli and strains useful for said method
12/16/1999WO1999064606A1 Tankyrase, a trfi binding protein
12/16/1999WO1999064605A2 Cloning of human choline/ethanolaminephosphotransferases; synthesis of phosphatidylcholine, phosphatidylethanolamine, and platelet activating factor
12/16/1999WO1999064604A2 Attenuated pestiviruses
12/16/1999WO1999064603A2 ENHANCEMENT OF B CELL ACTIVATION AND IMMUNOGLOBULIN SECRETION BY CO-STIMULATION OF RECEPTORS FOR ANTIGEN AND EBV Gp350/220
12/16/1999WO1999064602A2 Moraxella catarrhalis polynucleotides and polypeptides
12/16/1999WO1999064601A1 Novel maize orthologues of bacterial reca proteins
12/16/1999WO1999064600A1 NUCLEOTIDE SEQUENCES OF THE APPLE LRPKm1 GENE, ENCODED AMINO ACID SEQUENCE AND USES THEREOF
12/16/1999WO1999064599A1 Cyclin-dependent kinase inhibitors as plant growth regulators
12/16/1999WO1999064598A2 Novel insulin analogs with enhanced zinc binding
12/16/1999WO1999064597A1 β2 MICROGLOBULIN FUSION PROTEINS AND HIGH AFFINITY VARIANTS
12/16/1999WO1999064596A2 Proteins regulating gene expression
12/16/1999WO1999064595A1 THERAPEUTIC AND DIAGNOSTIC DOMAIN 1 β2GPI POLYPEPTIDES AND METHODS OF USING SAME
12/16/1999WO1999064594A2 Genes and gene expression products that are differentially regulated in prostate cancer
12/16/1999WO1999064593A2 Cell cycle regulation proteins
12/16/1999WO1999064592A2 Green fluorescent proteins for measuring the ph of a biological sample
12/16/1999WO1999064591A1 Antibody against lar phosphatase subunit
12/16/1999WO1999064590A1 Polymorphic markers of prostate carcinoma tumor antigen-1 (pcta-1)
12/16/1999WO1999064589A1 Human receptor tyrosine kinase
12/16/1999WO1999064588A1 TGFβ RII RECEPTOR NUCLEIC SEQUENCE, CODED PEPTIDE, AND USES
12/16/1999WO1999064587A1 Polypeptides with beta-secretase type activity
12/16/1999WO1999064586A2 Phagocytic assay method