Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
11/1999
11/30/1999US5994521 Full length transcript (FLt) promoter from figwort mosaic caulimovirus (FMV) and use to express chimeric genes in plant cells
11/30/1999US5994519 Labelling proteins, peptides, or ligands by binding first marker ligand-enzyme conjugate to a specific binding pair member; binding label molecules to proteins, peptides, or ligands; isolating and/or purifying labelled product
11/30/1999US5994518 Method of producing a polypeptide having human granulocyte colony stimulating factor activity
11/30/1999US5994516 Mutated proteins encoded by a lentivirus mutated env gene, peptide fragments and expression vectors
11/30/1999US5994513 Oncoprotein protein kinase
11/30/1999US5994512 Antibody derivatives for controlling gene expression
11/30/1999US5994511 Anti-IgE antibodies and methods of improving polypeptides
11/30/1999US5994506 An isolated polypeptide comprising at least 50 contiguous amino acid residues
11/30/1999US5994504 Vitamin D response element binding protein
11/30/1999US5994503 Nucleotide and protein sequences of lats genes and methods based thereon
11/30/1999US5994339 Oxidant scavengers
11/30/1999US5994320 Antisense oligonucleotides and methods for treating central nervous system tumors
11/30/1999US5994319 Synergistic mixture
11/30/1999US5994317 Quaternary cytofectins
11/30/1999US5994315 Low adenosine agent, composition, kit and method for treatment of airway disease
11/30/1999US5994313 Regulated apoptosis
11/30/1999US5994306 Fine-tuned protegrins
11/30/1999US5994304 Polypeptide
11/30/1999US5994301 Corpuscles of stannius protein, stanniocalcin
11/30/1999US5994300 Vascular endothelial cell growth factor C subunit
11/30/1999US5994137 Obtaining mycobacteriophage with an escherichia bacteriophage cosmid and a transposon inserted in a non-essential region, infecting the bacterium with the phasmid to deliver the transposon to the bacterium chromosome causing gene mutations
11/30/1999US5994136 Method and means for producing high titer, safe, recombinant lentivirus vectors
11/30/1999US5994135 Use of 5-bromoindole-3-acetic acid (5-b-iaa) as an auxin affecting plant cell growth; for the regeneration of both plant tissues and transgenic plant tissues
11/30/1999US5994134 Preparing a culture of producer cells coated microcarriers, seeding the bioreactors at high density, increasing infectivity of the producer cells to the virus, culturing the cells under perfusion conditions in serum containing media
11/30/1999US5994132 Adenovirus vectors
11/30/1999US5994128 Primary cells containing a nucleic acid molecule from the adenovirus early genes, eia and eib; an encapsidating signal sequence and an inverted terminal repeat with no overlapping sequences with the target cells; autoimmune disease therapy
11/30/1999US5994127 In vivo production and delivery of erythropoietin or insulinotropin for gene therapy
11/30/1999US5994125 A synthetic oligonucleotide; anticoagulant, hypertensive agent, antiinflammatory agent,
11/30/1999US5994124 A protein specific to target rnas; therapy for human immunodeficiency virus
11/30/1999US5994123 An exogenous dna molecule which initiates rna transcription; for the constituitive expression of transgenic plants; improve nutrional value, pest resistance, disease resistance and improved yields
11/30/1999US5994119 Mammalian regulator of nonsense-mediated RNA decay
11/30/1999US5994118 DNA encoding phage resistance protein
11/30/1999US5994117 Use of Bacillus Subtilis as an endophyte for the control of diseases caused by fungi
11/30/1999US5994116 Preparing a non-infectious viral particle having defects in its replication proteins; infecting cells with the virus and a chemical inhibitor of dna synthesis, preventing viral replication and recovering the desired particles; vaccines
11/30/1999US5994114 A polynucleotide which codes for a protein having taxadiene synthase activity; chemotherapy
11/30/1999US5994113 Enzymes with aminopeptidase activity
11/30/1999US5994112 A polynucleotide which codes a protein; antiproliferative agents, anticarcinogenic agents, antiinflammatory agents
11/30/1999US5994111 A polypeptide; treatment and diagnosis of respiratory infections, septic arthritis, cardiovascular infections, gastrointestinal infections, toxic shock syndrome; antibiotics
11/30/1999US5994109 Nucleic acid transporter system and methods of use
11/30/1999US5994108 A human enbryonic kidney cell line which produces increased levels of the human immunodefiency virus mutant stem-loop rna structure in the presence of a transactivation protein; vaccines for human immunodefiency virus
11/30/1999US5994106 Stocks of recombinant, replication-deficient adenovirus free of replication-competent adenovirus
11/30/1999US5994104 Interleukin-12 fusion protein
11/30/1999US5994103 Human stanniocalcin-alpha
11/30/1999US5994102 Polynucleotides encoding prostatic growth factor and process for producing prostatic growth factor polypeptides
11/30/1999US5994101 DNA encoding gidA1 polypeptides
11/30/1999US5994100 HAS2 splicing variant HOEFC11: a target in chronic renal failure, inflammatory diseases and myocardial ischemia
11/30/1999US5994098 G protein coupled receptor gene; treatment of pain, diabetes, eating disorders, asthma; hypotensive/hypertensive agents; parkinson's/huntington's/cardiovascular diseases, ulcers, anticarcinogenic/antiallergens agents; osteoprosis,
11/30/1999US5994097 Polynucleotide encoding human G-protein coupled receptor
11/30/1999US5994096 Regulator
11/30/1999US5994095 MTS2 gene
11/30/1999US5994094 A bone morphogenetic protein; treatment of osteoporosis, prevent transplant rejection; wound healing agents; regeneration of bones, cartilage, connective tissue, skin, mucous membranes, epithelium and teeth
11/30/1999US5994090 Using a phosphocholine-containing glycoglycerophospholipid from a mycoplasma as an immunogen to obtain an antibody specific to the glycoglycerophospholipid; aids therapy
11/30/1999US5994088 Treating cells with a glycoprotein substrate from a group; reserpine, gramicidin, cyclosporine, vincristine, actinomycin d, taxol, verapamil and vinblastine; reacting cells with antibody to glycoprotein/substrate, detect increase binding
11/30/1999US5994087 Mammalian melanocortin receptors and uses
11/30/1999US5994084 A cell that enodgenously expresses the protein tau and having a gene encoding a kinase that modulates phosphorylation of the protein tau; cultured cell exhibited hyperphosphorylation of tau and neurofibrillary tangles; preventing alzheimer's
11/30/1999US5994083 Collect serum samples from infected pateints with antibodies and a healthy individual, identify antibodies which bind antigens specific to the disease from phage library; select phages that display antigen recognized by antibody; vaccines
11/30/1999US5994082 Methods for the identification of inhibitors which suppress the activity of proteins displaying CIITA activity
11/30/1999US5994080 Isolating nucleic acid from an i
11/30/1999US5994077 Establishing a selectable library containing regulatory elements linked to a mutant green fluorescent protein marker, transforming and isolating active element by fluorescent intensity cell sorting against wild type aequorea victoria
11/30/1999US5994072 A b-band gene cluster involved in the biosythesis and assembly of lipopolysaccharides; treatment of infections in burn patients, transplants and cystic fibrosis
11/30/1999US5994070 A nucleic acid and polypeptide which regulates a variety of cellular processes; diagnosis and treatment of nervous sytem disorders; alzheimer's/huntinton's/parkinson's diseases
11/30/1999US5994069 Forming nucleic acid cleavage structure on target sequence and cleaving the nucleic acid in a site specific manner using structure specific 5'nucleases then annealing complementary oligonucleotides to detect target nucleic acid
11/30/1999US5994066 Species-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
11/30/1999US5994065 Blocking non-specific sites on a solid support having immobilized target ligands comprising nucleic acids by reacting with an acyclic or heterocyclic carboxylic anhydride; contacting with a probe
11/30/1999US5994060 Gro genes, proteins, and uses thereof
11/30/1999US5994056 Homogeneous methods for nucleic acid amplification and detection
11/30/1999US5994054 Creating an expression library, transfecting cells with a dna molecule which contains a long terminal repeat promoter sequence of human immunodeficiency virus adjacent to a reporter molecule, measuring viricide activity
11/30/1999US5994053 Phragmoplastin and methods of examining cell plate development
11/30/1999US5993828 Administering to the subject an effective dose of a composition comprising inactivated tumor cells having urinary tumor associated antigen on the cell surface and at least one tumor associated antigen
11/30/1999US5993827 Binding domains from plasmodium vivax and plasmodium falciparum erythrocyte binding proteins
11/30/1999US5993824 Production of attenuated respiratory syncytial virus vaccines from cloned nucleotide sequences
11/30/1999US5993821 Antigens and vaccines containing said vlps that may be effective in treatment of infections caused by such viruses.
11/30/1999US5993818 Use of autoantibodies for tumor therapy and prophylaxis
11/30/1999US5993816 Methods to inhibit humoral immune responses, immunoglobulin production and B cell activation with 5c8-specific antibodies
11/30/1999US5993814 Agents for inhibition of chemoattractant
11/30/1999US5993813 Family of high affinity, modified antibodies for cancer treatment
11/30/1999US5993808 Chitinase, DNA coding therefor and plants containing same
11/30/1999US5993801 Gene therapy using stromal cells
11/30/1999US5993800 Methods for prolonging the expression of a heterologous gene of interest using soluble CTLA4 molecules and an antiCD40 ligand
11/30/1999US5993799 Methods of using genetically engineered cells that produce insulin in response to glucose
11/30/1999US5993778 Functional expression of, and assay for, functional cellular receptors in vivo
11/30/1999US5993631 Methods of analysis/separation
11/30/1999US5992923 Reinforced beam assembly
11/30/1999CA2186588C Novel cationic phospholipids for transfection
11/30/1999CA2155387C Species-specific detection of mycobacterium kansasii
11/30/1999CA2154178C Plants resistant to infection by plrv
11/30/1999CA2128250C Insecticidally effective peptides
11/30/1999CA2024607C Recombinant dna method and host cells
11/30/1999CA1340835C Expression vectors and methods for intracellular protein production
11/30/1999CA1340834C Derivatives of human/bovine basic fibroblast growth factor
11/30/1999CA1340832C Recombinant cmv neutralizing proteins
11/30/1999CA1340831C Ribozymes
11/30/1999CA1340830C Process for production of physiologically active peptide containing cysteine residue
11/29/1999CA2272231A1 Oligonucleotides for detecting enteric hemorrhagic e. coli and detection method using the same
11/25/1999WO1999060630A1 Infrared thermography
11/25/1999WO1999060408A2 Assay involving protein binding to 3' untranslated mrna sequences
11/25/1999WO1999060407A1 Assays, methods and means for modulating e2f activity
11/25/1999WO1999060400A1 Bis-biotin compounds for specific binding assays
11/25/1999WO1999060381A1 Instrument for monitoring polymerase chain reaction of dna
11/25/1999WO1999060171A1 Compounds, screening methods, and uses involving anti-apoptotic genes and gene products