Patents for C07D 501 - Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula: , e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (7,574) |
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10/03/1989 | US4871730 Cephem compounds |
09/27/1989 | EP0334592A2 A process for preparing 3-unsubstituted cephalosporins and 1-carba(dethia)cephalosporins |
09/27/1989 | EP0334590A2 3-(Substituted)-1-carba(dethia)-3-cephems and cephalosporins and a process for production therefor |
09/27/1989 | EP0334281A2 Cephalosporin derivatives and process for their preparation |
09/26/1989 | US4870168 Palladium compound and trifurylphosphine as catalyst |
09/20/1989 | EP0333154A2 Process for the preparation of cephem derivatives and intermediates therefor |
09/20/1989 | EP0333082A2 Cephem compounds, their production and use |
09/19/1989 | US4868295 Cephalosporin antibiotic, by-product inhibition |
09/19/1989 | US4868294 Process for preparing cephalosporin intermediates |
09/19/1989 | US4868174 Cephalosporin antibiotics |
09/19/1989 | US4868173 Cephalosporin derivatives |
09/19/1989 | CA1259606A1 Cephem derivatives and processes for their manufacture |
09/13/1989 | CN1035509A Cephalosporins derivatives and process for preparing them |
09/12/1989 | US4866169 Antibiotics cephalosporins |
09/12/1989 | US4866055 Antibiotics |
09/06/1989 | CN1035283A Method of producing tert-butyl 3-oxobutyrate and use thereof |
09/05/1989 | US4864022 7-(2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(alkyl) oxyiminoacetamido) substituted |
08/30/1989 | EP0329785A1 Cephalosporin derivatives |
08/29/1989 | US4861769 Cephem compounds |
08/24/1989 | WO1989007600A1 Zinc ceftiofur complexes |
08/23/1989 | EP0329457A2 Cephalosporin derivatives |
08/23/1989 | EP0329286A1 Zinc ceftiofur complexes |
08/23/1989 | EP0329008A2 Cephalosporinderivatives and process for its preparation |
08/16/1989 | CN1034727A Crystals of cephem hydrochloride |
08/16/1989 | CN1034670A Process for stabilizing cephalosporins derivatives by drying them with stabiliser and stability composition containing cephalosporins derivatives |
08/09/1989 | EP0327358A2 Ceftazidime dihydrochloride formic acid solvates |
08/09/1989 | EP0327081A2 Alpha-crystals of cefazolin sodium |
08/08/1989 | US4855420 Cephalosporin derivatives |
08/08/1989 | US4855419 Application of 4-[1-oxoalkyl]-2,5-oxazolidinediones in selective stereospecific formation of biologically active α-lactams |
08/08/1989 | US4855418 Process for production of ceophalosporins |
08/01/1989 | US4853468 Process for the preparation of cephem derivatives |
07/26/1989 | EP0325112A1 Stabilization of cephalosporin derivatives by drying with a stabilizer, and stable preparations containing cephalosporin derivatives |
07/19/1989 | EP0324418A2 Method for production of t-butyl- 3-oxobutyrates and their use |
07/12/1989 | CN1033808A Oral cynnematin derivate, preparation process and use thereof |
07/11/1989 | US4847373 Coupling a 3-chloromethyl-3-cephems, palladium and phosphine catalysts |
07/05/1989 | EP0323177A2 Cephalosporin derivatives |
07/05/1989 | EP0322810A2 Cephalosporin derivatives |
07/04/1989 | US4845211 Amino-3-substituted-methyl-3-cephem-4-carboxylic acid and lower alkylsilyl derivatives thereof |
07/04/1989 | US4845087 Crystallized cephem-acid addition salts, and a process for the preparation thereof |
06/28/1989 | EP0322032A2 One-step enzymatic conversion of cephalosporin C and derivatives to 7-aminocephalosporanic acid and derivatives |
06/28/1989 | EP0321562A1 Crystalline cephalosporin compounds, process for their preparation, and intermediates for their preparation |
06/27/1989 | US4843164 Cephalosporin intermediate; antibiotic |
06/21/1989 | EP0321364A2 Orally administrable cephalosporin derivatives, and the production and uses thereof |
06/20/1989 | US4841044 Cephalosporin derivatives |
06/20/1989 | US4840945 Antibiotics effective against methicillin resistant staphylococcus |
06/13/1989 | US4839351 Cephalosporins |
06/13/1989 | US4839350 Antibiotics |
06/07/1989 | EP0319019A2 Crystals of cephem hydrochloride |
06/07/1989 | EP0318767A2 Esters of pharmacologically active carboxylic acids splittable under physiological conditions |
06/07/1989 | EP0318682A2 Tricyclic thiazole derivatives |
05/30/1989 | US4835267 One-step acylation |
05/30/1989 | US4835150 Cephem compounds |
05/30/1989 | CA1254884A1 Derivatives of substituted cephalosporanic acid and antibiotics comprising the same |
05/24/1989 | EP0317484A2 N,N'-carboxyl-bis-(4-ethyl-2,3-dioxo)-piperazine, process for the preparation thereof and use thereof |
05/23/1989 | US4833242 Antibiotics, bactericides |
05/23/1989 | US4833134 Antibiotics, bacterides |
05/18/1989 | WO1989004313A1 Cephalosporin antibiotics |
05/17/1989 | EP0315997A2 Cephalosporin compounds and antibacterial agents |
05/10/1989 | EP0315518A1 Cephalosporins having in position 3 a substituted vinyl radical, their process for preparation, their application as medicaments, compositions containing them and intermediates |
05/09/1989 | CA1253856A1 Brain-specific drug delivery |
05/02/1989 | US4826972 Method for preparing crystalline cephalosporin derivative |
05/02/1989 | CA1253486A1 Cephalosporins, processes for producing the same, antibacterial agent containing the same, intermediates thereof and process for producing the intermediates |
04/26/1989 | EP0312844A1 Cephalosporin intermediates, process for their preparation and their use |
04/26/1989 | CN1032540A Cephem compound and process for preparation thereof |
04/19/1989 | EP0120094B1 Azetidinone compounds |
04/18/1989 | US4822888 New cepham compounds and processes for the production thereof |
04/18/1989 | US4822786 Cephalosporin compounds, and antibacterial agents |
04/13/1989 | DE3732323A1 Safety valve for the protection of air pumps against the backflow of water, other liquids and air backpressure |
04/12/1989 | EP0311521A1 Cephalosporin derivatives with improved pharmacokinetics, process for their preparation, pharmaceutical compositions containing them and intermediate |
04/12/1989 | EP0311254A2 Beta-lactam compound and process for production thereof |
04/12/1989 | EP0310948A2 Process for the preparation of optically pure phenyl ring-substituted phenyl alamine derivatives |
04/12/1989 | EP0310909A2 Heteroannelated phenyl glycine beta-lactam antibiotics, process for their preparation and their use as therapeutical agents |
04/12/1989 | CN1032341A New crystal cephalosporin derivates and their preparing process |
04/11/1989 | US4820833 Purification by spray drying precipitation, freeze drying; cephalosporins |
04/11/1989 | US4820832 Reduction of corresponding 3-halo or 3-sulfonyl ester with palladium |
03/29/1989 | EP0308559A2 Cephalosporins, process for their preparation, pharmaceutical compositions containing them and intermediates |
03/29/1989 | EP0178980B1 Cephalosporin derivatives, process for their preparation and their antibiotic application |
03/28/1989 | CA1251785A1 Cephalosporin hydroxamic acids |
03/22/1989 | EP0307804A2 Cephem compound and a process for preparation thereof |
03/21/1989 | US4814328 Cephalosporin derivatives, and antibacterial agents |
03/15/1989 | EP0306863A2 Cephem compounds and processes for preparation thereof |
03/14/1989 | US4812562 Cephalosporin derivatives |
03/14/1989 | US4812561 Crystalline hydrate of oral cephalosporin and its composition |
03/08/1989 | EP0305625A1 Crystalline cephalosporine derivative |
03/08/1989 | CN1031534A Process for preparation of 3-exomethylenecepham derivatives |
03/07/1989 | US4810788 Azetidinone disulfide derivatives and a process for preparing the same |
03/07/1989 | US4810702 Antibacterial agent for mammal use comprising cephalosporin derivatives as an effective ingredient |
03/01/1989 | EP0305111A2 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions |
03/01/1989 | EP0304858A2 Cephem compounds, their production and use |
03/01/1989 | CN1031378A Antibiotic compounds |
02/28/1989 | US4808724 2-aminothiazolyl-containing β-lactam antibiotics |
02/28/1989 | US4808712 Reacting thiazolinoazetidinone with alkali metal iodide, then nucleophilic reagent, sulfur compound, and ammonia |
02/28/1989 | US4808711 Cephalosporin derivatives |
02/28/1989 | US4808617 Heat resistant antibiotic |
02/28/1989 | US4808577 Boric acid or a salt |
02/22/1989 | EP0304158A1 Cephalosporins, processes for their preparation and pharmaceutical compositions containing them |
02/22/1989 | EP0304155A2 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions |
02/22/1989 | EP0304036A2 3-(substituted)propenyl-7-(aminothiazolylacetamido)ceph-3-em-4-carboxylic acids and esters thereof |
02/22/1989 | EP0304019A2 Novel crystalline 7-(2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamido)-3-vinyl-3-cephem-4-carboxylic acid (syn isomer) |
02/22/1989 | CN1031231A Water-soluble antibiotic composition and water-soluble salts of new cephem compounds |