Patents
Patents for C07D 501 - Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula: , e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (7,574)
10/1989
10/03/1989US4871730 Cephem compounds
09/1989
09/27/1989EP0334592A2 A process for preparing 3-unsubstituted cephalosporins and 1-carba(dethia)cephalosporins
09/27/1989EP0334590A2 3-(Substituted)-1-carba(dethia)-3-cephems and cephalosporins and a process for production therefor
09/27/1989EP0334281A2 Cephalosporin derivatives and process for their preparation
09/26/1989US4870168 Palladium compound and trifurylphosphine as catalyst
09/20/1989EP0333154A2 Process for the preparation of cephem derivatives and intermediates therefor
09/20/1989EP0333082A2 Cephem compounds, their production and use
09/19/1989US4868295 Cephalosporin antibiotic, by-product inhibition
09/19/1989US4868294 Process for preparing cephalosporin intermediates
09/19/1989US4868174 Cephalosporin antibiotics
09/19/1989US4868173 Cephalosporin derivatives
09/19/1989CA1259606A1 Cephem derivatives and processes for their manufacture
09/13/1989CN1035509A Cephalosporins derivatives and process for preparing them
09/12/1989US4866169 Antibiotics cephalosporins
09/12/1989US4866055 Antibiotics
09/06/1989CN1035283A Method of producing tert-butyl 3-oxobutyrate and use thereof
09/05/1989US4864022 7-(2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(alkyl) oxyiminoacetamido) substituted
08/1989
08/30/1989EP0329785A1 Cephalosporin derivatives
08/29/1989US4861769 Cephem compounds
08/24/1989WO1989007600A1 Zinc ceftiofur complexes
08/23/1989EP0329457A2 Cephalosporin derivatives
08/23/1989EP0329286A1 Zinc ceftiofur complexes
08/23/1989EP0329008A2 Cephalosporinderivatives and process for its preparation
08/16/1989CN1034727A Crystals of cephem hydrochloride
08/16/1989CN1034670A Process for stabilizing cephalosporins derivatives by drying them with stabiliser and stability composition containing cephalosporins derivatives
08/09/1989EP0327358A2 Ceftazidime dihydrochloride formic acid solvates
08/09/1989EP0327081A2 Alpha-crystals of cefazolin sodium
08/08/1989US4855420 Cephalosporin derivatives
08/08/1989US4855419 Application of 4-[1-oxoalkyl]-2,5-oxazolidinediones in selective stereospecific formation of biologically active α-lactams
08/08/1989US4855418 Process for production of ceophalosporins
08/01/1989US4853468 Process for the preparation of cephem derivatives
07/1989
07/26/1989EP0325112A1 Stabilization of cephalosporin derivatives by drying with a stabilizer, and stable preparations containing cephalosporin derivatives
07/19/1989EP0324418A2 Method for production of t-butyl- 3-oxobutyrates and their use
07/12/1989CN1033808A Oral cynnematin derivate, preparation process and use thereof
07/11/1989US4847373 Coupling a 3-chloromethyl-3-cephems, palladium and phosphine catalysts
07/05/1989EP0323177A2 Cephalosporin derivatives
07/05/1989EP0322810A2 Cephalosporin derivatives
07/04/1989US4845211 Amino-3-substituted-methyl-3-cephem-4-carboxylic acid and lower alkylsilyl derivatives thereof
07/04/1989US4845087 Crystallized cephem-acid addition salts, and a process for the preparation thereof
06/1989
06/28/1989EP0322032A2 One-step enzymatic conversion of cephalosporin C and derivatives to 7-aminocephalosporanic acid and derivatives
06/28/1989EP0321562A1 Crystalline cephalosporin compounds, process for their preparation, and intermediates for their preparation
06/27/1989US4843164 Cephalosporin intermediate; antibiotic
06/21/1989EP0321364A2 Orally administrable cephalosporin derivatives, and the production and uses thereof
06/20/1989US4841044 Cephalosporin derivatives
06/20/1989US4840945 Antibiotics effective against methicillin resistant staphylococcus
06/13/1989US4839351 Cephalosporins
06/13/1989US4839350 Antibiotics
06/07/1989EP0319019A2 Crystals of cephem hydrochloride
06/07/1989EP0318767A2 Esters of pharmacologically active carboxylic acids splittable under physiological conditions
06/07/1989EP0318682A2 Tricyclic thiazole derivatives
05/1989
05/30/1989US4835267 One-step acylation
05/30/1989US4835150 Cephem compounds
05/30/1989CA1254884A1 Derivatives of substituted cephalosporanic acid and antibiotics comprising the same
05/24/1989EP0317484A2 N,N'-carboxyl-bis-(4-ethyl-2,3-dioxo)-piperazine, process for the preparation thereof and use thereof
05/23/1989US4833242 Antibiotics, bactericides
05/23/1989US4833134 Antibiotics, bacterides
05/18/1989WO1989004313A1 Cephalosporin antibiotics
05/17/1989EP0315997A2 Cephalosporin compounds and antibacterial agents
05/10/1989EP0315518A1 Cephalosporins having in position 3 a substituted vinyl radical, their process for preparation, their application as medicaments, compositions containing them and intermediates
05/09/1989CA1253856A1 Brain-specific drug delivery
05/02/1989US4826972 Method for preparing crystalline cephalosporin derivative
05/02/1989CA1253486A1 Cephalosporins, processes for producing the same, antibacterial agent containing the same, intermediates thereof and process for producing the intermediates
04/1989
04/26/1989EP0312844A1 Cephalosporin intermediates, process for their preparation and their use
04/26/1989CN1032540A Cephem compound and process for preparation thereof
04/19/1989EP0120094B1 Azetidinone compounds
04/18/1989US4822888 New cepham compounds and processes for the production thereof
04/18/1989US4822786 Cephalosporin compounds, and antibacterial agents
04/13/1989DE3732323A1 Safety valve for the protection of air pumps against the backflow of water, other liquids and air backpressure
04/12/1989EP0311521A1 Cephalosporin derivatives with improved pharmacokinetics, process for their preparation, pharmaceutical compositions containing them and intermediate
04/12/1989EP0311254A2 Beta-lactam compound and process for production thereof
04/12/1989EP0310948A2 Process for the preparation of optically pure phenyl ring-substituted phenyl alamine derivatives
04/12/1989EP0310909A2 Heteroannelated phenyl glycine beta-lactam antibiotics, process for their preparation and their use as therapeutical agents
04/12/1989CN1032341A New crystal cephalosporin derivates and their preparing process
04/11/1989US4820833 Purification by spray drying precipitation, freeze drying; cephalosporins
04/11/1989US4820832 Reduction of corresponding 3-halo or 3-sulfonyl ester with palladium
03/1989
03/29/1989EP0308559A2 Cephalosporins, process for their preparation, pharmaceutical compositions containing them and intermediates
03/29/1989EP0178980B1 Cephalosporin derivatives, process for their preparation and their antibiotic application
03/28/1989CA1251785A1 Cephalosporin hydroxamic acids
03/22/1989EP0307804A2 Cephem compound and a process for preparation thereof
03/21/1989US4814328 Cephalosporin derivatives, and antibacterial agents
03/15/1989EP0306863A2 Cephem compounds and processes for preparation thereof
03/14/1989US4812562 Cephalosporin derivatives
03/14/1989US4812561 Crystalline hydrate of oral cephalosporin and its composition
03/08/1989EP0305625A1 Crystalline cephalosporine derivative
03/08/1989CN1031534A Process for preparation of 3-exomethylenecepham derivatives
03/07/1989US4810788 Azetidinone disulfide derivatives and a process for preparing the same
03/07/1989US4810702 Antibacterial agent for mammal use comprising cephalosporin derivatives as an effective ingredient
03/01/1989EP0305111A2 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions
03/01/1989EP0304858A2 Cephem compounds, their production and use
03/01/1989CN1031378A Antibiotic compounds
02/1989
02/28/1989US4808724 2-aminothiazolyl-containing β-lactam antibiotics
02/28/1989US4808712 Reacting thiazolinoazetidinone with alkali metal iodide, then nucleophilic reagent, sulfur compound, and ammonia
02/28/1989US4808711 Cephalosporin derivatives
02/28/1989US4808617 Heat resistant antibiotic
02/28/1989US4808577 Boric acid or a salt
02/22/1989EP0304158A1 Cephalosporins, processes for their preparation and pharmaceutical compositions containing them
02/22/1989EP0304155A2 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions
02/22/1989EP0304036A2 3-(substituted)propenyl-7-(aminothiazolylacetamido)ceph-3-em-4-carboxylic acids and esters thereof
02/22/1989EP0304019A2 Novel crystalline 7-(2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamido)-3-vinyl-3-cephem-4-carboxylic acid (syn isomer)
02/22/1989CN1031231A Water-soluble antibiotic composition and water-soluble salts of new cephem compounds
1 ... 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 ... 76