Patents
Patents for C07D 501 - Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula: , e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (7,574)
02/1989
02/15/1989EP0303223A2 Water-soluble antibiotic composition and water-soluble salts of new cephem compounds
02/15/1989EP0303172A2 Oxyimino-cephalosporins
02/15/1989CN1031085A Method for preparing crystalline cefadroxil monoltydrate
02/14/1989US4804752 Bactericides
02/14/1989CA1249969A1 Pharmaceutical formulations for ceftazidime
02/08/1989EP0302145A2 Method for preparing crystalline cefadroxil monohydrate
02/07/1989US4803280 Intermediates for preparation of antibiotics
02/07/1989US4803267 Acylation of cephalosporin c
02/01/1989EP0301877A1 A method of deprotection of 3-amino azetidinones
02/01/1989EP0301257A2 Cephem Derivatives and a process for their manufacture
02/01/1989CN1030760A New method for prepg. cephalkenes and new ceplalosporin derivatives
01/1989
01/31/1989US4801720 Chemical intermediates for cephalosporins
01/31/1989US4801703 Phosphorus compounds
01/26/1989WO1989000572A1 Process for the preparation of 3-exomethylene cepham derivatives
01/25/1989EP0300665A2 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions
01/25/1989EP0300664A2 Cephalosporin compounds
01/25/1989EP0300546A1 Process for the preparation of cephem compounds and cephalosporin derivatives
01/25/1989EP0300423A2 Cephalosporin compound, method of its production and composition for prevention and treatment of bacterial infectious diseases
01/25/1989EP0300121A2 New intermediates for the preparation of cephem compounds, processes for the preparation thereof and their use
01/24/1989US4800199 3-[2-thiazoloamino]-8-oxo-7-substituted-5-thia-1-azabicyclo-[4.2.0]oct-2-ene-2-carboxylic acid and salts thereof and diphenylmethyl esters thereof
01/18/1989EP0299728A2 Carbonylation process for beta-lactam antibiotics
01/18/1989EP0299587A1 Process for the preparation of 3-exomethylenecepham derivatives
01/11/1989EP0298502A2 Cephem derivative crystals and a process for their preparation
01/10/1989US4797395 1-Acyloxyalkyl esters of cephalosporin
01/03/1989CA1248088A1 Crystalline cephalosporin hydrohalid salts
12/1988
12/29/1988WO1988010263A1 Crystalline cephalosporin compounds, process for their preparation, and intermediates for their preparation
12/29/1988WO1988010262A1 Crystalline cephalosporin compound
12/29/1988WO1988010256A1 Application of 4-[1-oxoalkyl]-2,5-oxazolidinediones in selective stereospecific formation of biologically active beta-lactams
12/28/1988CN88103111A Substituted vinylcephalosporins, processes for their preparation and their use as medicaments
12/28/1988CN88100566A Substantially anhydrous crystalline cefadroxil and method for producing it
12/28/1988CA1247596A Process for producing antibiotic compounds derived from cephalosporins
12/21/1988EP0295630A2 Cephalosporin derivatives
12/21/1988EP0295341A1 Cephalosporins
12/21/1988EP0295333A2 Substantially anhydrous crystalline cefadroxil and method for producing it
12/21/1988CN88103202A Substituted vinylcephalosporing, processes for preparing them and use as medicaments
12/21/1988CN88102932A Purine-substituted oxygen heterocycle butanes
12/21/1988CN88101104A Pharmaceutical composition pharmaceutical granulate and process for their preparation
12/20/1988CA1247109A2 Intermediates for the preparation of cephalosporins and their preparation
12/20/1988CA1247029A1 Cephem compounds and their production
12/14/1988CN88102467A Process for preparing cephalosporins compounds and antibiotics
12/13/1988US4791197 Cephalosporin compounds
12/13/1988US4791196 Crystalline cephem carboxylic acid addition salt
12/13/1988CA1246545A1 Chlorocefadroxil monohydrate
12/07/1988EP0293771A2 Cephalosporin compound and pharmaceutical composition thereof
12/07/1988EP0293532A1 6- or 7-beta-[2-[4-(substituted)-2,3-dioxopiperazin-1-yl) carbonylamino]-(substituted)acetamido]-penicillin and cephalosporin derivatives
11/1988
11/30/1988EP0292808A2 Substituted vinyl cephalosporins, process for their preparation and their use as medicines
11/30/1988EP0292806A2 Substituted vinyl cephalosporins, process for their preparation and their use as medicines
11/30/1988CN88101895A Crystalline cefadroxil and method for producing it
11/29/1988US4788282 Carbapenicillins
11/29/1988CA1245630A1 Crystalline modification of ceftazidim
11/29/1988CA1245629A1 Cephalosporin intermediates
11/23/1988EP0292230A2 Phenylacetic acid derivatives and their use in the preparation of cephalosporin antibiotics
11/23/1988EP0291917A2 Novel oxetanocins
11/23/1988CN88101644A Container using for storing an injector, which can be picked off, stored safely and be treated endly within it
11/22/1988US4786633 Cephalosporin compounds
11/15/1988US4785090 Antibiotics, bactericides
11/15/1988US4784995 Cephalosporin compounds
11/15/1988CA1244823A1 Thiazole derivatives
11/09/1988EP0290136A2 7-Beta-substituted-3-lower alkanoylacetoxymethyl-7-alpha-methoxy-3-cephem-4-carboxylic acid and process for production of same
11/08/1988US4783443 Amino acyl cephalosporin derivatives
11/02/1988EP0289002A2 Novel cephalosporin compounds and antibacterial agents
11/01/1988US4782162 Novel intermediates for the synthesis of cephalosporins
11/01/1988US4782158 Cephem antibiotic intermediates
10/1988
10/27/1988DE3711625A1 Process for the preparation of 3-methylenecephem compounds
10/26/1988EP0287751A2 Crystalline cefadroxil and method for producing it
10/20/1988EP0233271A4 Process for preparing cephalosporin intermediates.
10/19/1988EP0287116A2 Thiadiazolylacetamide cephem derivatives
10/18/1988CA1243298A1 Cephalosporin derivatives and salts thereof
10/18/1988CA1243297A1 Crystalline modification of ceftazidim
10/12/1988EP0286145A2 3-Heterocyclylthiomethyl cephalosporins
10/12/1988EP0286144A2 Heterocyclylthiomethylcephalosporins
10/05/1988EP0284954A2 Cephalosporinderivatives, process for their preparation and their use in pharmaceutical products
10/04/1988US4775751 Isolation from cephalexin hydrochloride
10/04/1988US4775750 Process for preparing sodium cefuroxime
10/04/1988CA1242700A1 Cefbuperazone crystalline triethylamine salt
09/1988
09/27/1988US4774330 Cephalosporin intermediates
09/21/1988EP0282531A1 Stable crystalline form of an intermediate product of cephalosporine.
09/20/1988US4772682 Cephem compounds
09/13/1988CA1241948A2 Substituted vinyl cephalosporins
09/07/1988EP0281391A1 Recombinant DNA expression vectors and DNA compounds that encode deacetoxycephalosporin C synthetase and deacetylcephalosporin C synthetase
09/07/1988EP0281200A1 Pharmaceutical composition, pharmaceutical granulate and process for their preparation
09/07/1988EP0281092A2 Cephalesporin derivatives and process for their preparation
09/06/1988US4769450 Process for recovering ceftazidime
08/1988
08/31/1988EP0280521A2 Cephalosporin compounds, process for their preparation and pharmaceutical compositions containing them
08/31/1988EP0280240A2 Cephalosporin derivatives, process for their preparation and antibacterial agents
08/31/1988EP0280157A2 Crystalline addition salts of cephem compounds and process for their preparation
08/30/1988US4767852 Acylation of 7-amino-3-cephem-4-carboxylic acids with a 2-oximinoacetic acid heterocycle-thio ester
08/30/1988US4767851 Process for the preparation of 7-amino and 7-substituted amino-desacetoxycephalosporins
08/30/1988US4767754 Cephalosporins
08/23/1988CA1240985A2 Preparation of cephalosporins
08/23/1988CA1240926A1 Use of cephem compounds as immunomodulators
08/17/1988EP0278656A1 Process for preparing ceftazidime pentahydrate
08/16/1988US4764606 Chemical intermediated
08/11/1988WO1988005777A1 Cephalosporin compounds or their salts, process for their preparation, and pharmaceutical compositions
08/11/1988WO1988005776A1 Cephalosporin compounds or their salts, process for their preparation, and parmaceutical compositions
08/09/1988CA1240314A2 Acyl derivatives
08/09/1988CA1240313A1 Form of cefuroxime ester, process for its preparation and composition containing it
08/02/1988US4761410 Cephem Compounds
08/02/1988US4761409 Antibiotics, bactericides
08/02/1988CA1239928A1 Cephalosporin derivatives, methods of production thereof and prophylactic and therapeutic agents for bacterial infection
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