Patents
Patents for C07D 501 - Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula: , e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (7,574)
07/1988
07/27/1988CN85106479B Crystalline d-6 (alpha-((2-aldo-3-furfurylidene-amino-1-imidazolidinyl) carbonyl amino)-2 thienylacetamido)-penicillanic acid salt with sodium, process thereof and use as medicine
07/26/1988US4760140 3-substituted-7-[5-substituted-2-thiazolyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid, diphenylmethyl esters
07/26/1988US4760060 3-heteroaralkylthio carbacephem compounds and antibacterial pharmaceutical composition
07/21/1988DE3740588A1 Temperaturstabiles breitband-antibiotikum Temperature stable broadband-antibiotic
07/19/1988US4758558 N-(substituted)-[7-(2-cyanoacetamido)cephalosporanic]amide derivatives having antibiotic utility
07/19/1988US4758557 Cephalosporin derivatives and bactericides containing the same
07/19/1988US4758556 Cephem derivatives
07/19/1988CA1239391A1 Recovery and/or purification of ceftazidime
07/19/1988CA1239390A1 Cefonicid monosodium salt
07/19/1988CA1239389A1 Crystallization process
07/12/1988US4757065 Cephalosporins
07/06/1988EP0273156A2 Method for producing pure crystalline products
07/05/1988US4755598 1'-(substituted)ethyl-7β-[2-(2-aminothiazol-4-yl)acetamido]-3-[[[1-(2-dimethylaminoethyl)-1H-tetrazol-5-yl]thio]methyl]ceph-3-em-4-carboxylate derivatives having antibacterial utility
07/05/1988US4755597 7-amino-3-(3-formamidopyridinium)methyl-3-cephem-4-carboxylate
07/05/1988CA1238910A1 Carboxyalkenoic acids
06/1988
06/29/1988EP0272827A2 3-Heterocyclicthiomethyl cephalosphorins
06/29/1988EP0272487A1 Cephalosporin derivatives and their crystalline derivatives, process for the preparation of the same, intermediates for use in the synthesis of the same, pharmaceutical compositions comprising the same, and the use of the same for the manufacture of a medicament having valuable therapeutic and preventative properties
06/29/1988CN87107753A New substituted cephalosporin sulfones as anti-inflammatory and antidegenerative agents
06/29/1988CN87105204A 酰基衍生物 Acyl derivatives
06/29/1988CN87101155A Antibacterial agent for mammal use comprising cephalosporin derivatives as effective ingredient
06/28/1988US4754031 Preparation of cephalosporins
06/28/1988US4754030 Cefbuperazone crystalline triethylamine salt
06/22/1988EP0272061A2 Crystalline cephalosporin antibiotic salts and solvates
06/22/1988EP0271916A2 Antibacterial agent for mammal use comprising cephalosporin derivatives as an effective ingredient
06/15/1988EP0271064A2 7-Amino-3-(substituted isoindolinium)methyl-3-cephem derivatives and process for their production
06/14/1988US4751295 Cephalosporin derivatives
06/02/1988WO1988003924A1 Novel cephalosporin derivatives and their crystalline derivatives
06/01/1988EP0269512A1 Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them
06/01/1988EP0269298A2 Cephalosporins, process for their preparation and pharmaceutical compositions
06/01/1988EP0269087A2 Cephalosporin derivatives, processes for the preparation of the same, intermediates for use in the synthesis of the same, pharmaceutical compositions comprisingthe same, and the use of the same for the manufacture of a medicament having valuable therapeutic and preventative properties
06/01/1988CN87107610A Process for preparing cephene derivs. and intermediate thereof
05/1988
05/31/1988US4748171 Cephem compounds having at the 3-position a (1,4-methylene-1-piperidinio)methyl group or a (1-quinuclidinio)methyl group
05/31/1988US4748170 Carboxyalkenamidocephalosporins
05/31/1988US4748163 Novel β-lactam antibiotics
05/31/1988CA1237427A1 Cephem compounds
05/25/1988EP0268343A2 Enzymatic process for 3-substituted cephalosporins
05/25/1988EP0268307A2 New starting compounds for cephem compounds and processes for their preparation
05/18/1988EP0267733A2 Cephalosporin compounds, process for their preparation and pharmaceutical compositions containing them
05/18/1988EP0267723A2 New substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents
05/18/1988EP0267427A1 Process for the preparation of cephalosporin derivatives
05/10/1988CA1236450A1 Synthesis route for bacampicillin
05/04/1988EP0266182A2 Gamma-lactonecarboxylic acid derivatives and their production
05/04/1988EP0266060A2 Cephalosporins, process for their preparation and pharmaceutical compositions containing them
05/04/1988CN87106452A New cephalosporanic olefinic compound and its preparation method
05/03/1988US4742174 Cephalosporin compounds
05/03/1988US4742053 Antibiotics
05/03/1988CA1236089A1 Ceftazidime
04/1988
04/27/1988EP0265185A2 Cephalosporins, processes for their preparation and pharmaceutical compositions containing them
04/26/1988CA1235690A1 Crystalline cephem-acid addition salts and processes for their preparation
04/26/1988CA1235689A1 Cephalosporin derivatives and a process for their preparation
04/21/1988WO1988002752A1 New process for producing cephalosporine derivatives
04/20/1988EP0264091A2 3-Propenylcephem derivative, preparation thereof, chemical intermediates therein, pharmaceutical composition and use
04/20/1988EP0263901A1 Conversion of cephalosporin hydrohalide salt to alkali metal salt
04/19/1988CA1235414A1 7-acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
04/12/1988US4737492 Sparingly soluble salts of cefamandole, and ophthalmic compositions containing same
04/12/1988CA1235116A1 Crystals of sodium cephemcarboxylate
04/06/1988EP0262744A2 A process for preparing 3-alkoxymethylcephalosphorins
04/06/1988EP0262696A2 Brain-specific drug delivery
04/05/1988US4736039 New cephem compounds and processes for preparation thereof
04/05/1988US4736026 Novel process for producing a cephalosporin
04/05/1988US4735940 Tricyclic pyridine derivatives and pharmaceutical compositions
04/05/1988US4735938 2-aminothiazolyl-containing β-lactam antibiotics
04/05/1988US4735937 Antibiotics
04/05/1988CA1234799A2 Cephalosporin derivatives
03/1988
03/31/1988DE3732457A1 Cephalosporin-verbindungen Cephalosporin compounds
03/30/1988EP0261990A2 Crystalline cephem carboxylic acid addition salt
03/30/1988EP0261615A2 Cephem compounds, processes for preparation thereof and pharmaceutical compositions comprising them
03/29/1988US4734409 Bactericide
03/29/1988US4734408 Purity
03/29/1988US4734407 Alpha-aminoacyl-penicillins and cephalosporins
03/24/1988WO1988002001A1 New stable crystalline form of an intermediate product of cephalosporine
03/23/1988CN87105009A Crystalline hydrate of oral cephalosporin and its composition
03/15/1988US4731443 7-acylamino-3-vinylcephalosporanic acid derivatives
03/15/1988US4731362 Alkylcarbamoyloxymethylcephem compounds
03/15/1988US4731361 Alkeneamidocephalosporin esters
03/09/1988CN87104995A Beta-lactam compound, method for preparing the same, medicinal composition for bacterially infectious disease therapy containing the same and intermediates for synthesis of the same
03/08/1988US4729992 Cephalosporin esters, their production and use
03/08/1988US4729991 Cephem compounds
03/08/1988CA1233815A1 Substituted vinyl cephalosporins
03/02/1988EP0257275A2 Cephalosporin and penicillin derivatives
03/01/1988US4728734 Bactericides
03/01/1988US4728733 C-3' thiadiazinyl cephalosporin analogs
03/01/1988US4728732 C-3'acylsulfonamido cephalosporin analogs
02/1988
02/24/1988EP0256577A2 Brain-specific drug delivery
02/24/1988EP0256542A2 Cephem compounds
02/23/1988US4727071 Cephalosporin compounds
02/23/1988US4727070 3-Propenzl cephalosporin isomer separation process and derivative
02/16/1988US4725592 1-Acyloxyalkyl esters of cephalosporin
02/02/1988US4723004 Antimicrobial agents
01/1988
01/28/1988DE3720681A1 New 1-sulphonyl:oxyl-6-tri:fluoromethyl-benzotriazole derivs. - useful as coupling agents in prodn. of 7-oxy:imino-acetamido-cephalosporin cpds.
01/27/1988EP0254495A2 Beta-Lactam compound, method for preparing the same, medicinal composition for bacterially infectious disease therapy containing the same and intermediates for synthesis of the same
01/26/1988CA1231941A1 Cephalosporin derivatives
01/26/1988CA1231940A1 Cephalosporin compounds and preparation thereof
01/20/1988EP0253507A2 Process for the preparation of cephalosporins
01/20/1988EP0253337A2 Tricyclic cepham compounds, their production and use
01/14/1988DE3721305A1 6-trifluormethyl-1h-benzotriazol-1-yl-diphenylphosphat und seine verwendung zur herstellung von cephalosporinderivaten 6-trifluoromethyl-1H-benzotriazol-1-yl-diphenyl phosphate and its use for the manufacture of cephalosporin derivatives
01/13/1988EP0252474A2 Hydrazine derivatives
01/13/1988EP0252473A2 7 Beta-(substituted) amino-3-substituted cephalosporanic acids and esters
01/13/1988CN87104590A Cephalosporim compounds, processes for their preparation and antibacterial agents
01/12/1988US4719206 Cephem compounds
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