Patents
Patents for C07D 491 - Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups , , or (29,726)
02/2004
02/11/2004CN1137886C Novel 2,3-dioxo-1,2,3,4-tetrahydro-quinoyxalinyl derivatives
02/11/2004CN1137884C Indazole compounds and pharmaceutical compositions for inhibiting protein kinases and methods for their use
02/10/2004US6689883 Substituted pyridines and pyridazines with angiogenesis inhibiting activity
02/10/2004US6689802 Polymorphs of an epothilone analog
02/10/2004US6689794 Aromatic sulfone hydroxamates and their use as protease inhibitors
02/10/2004US6689754 Heterocyclic glycyl β-alanine derivatives
02/10/2004CA2297134C A novel process for preparing intermediates or inhibitors of enkephalinase and angiotensin converting enzyme and intermediates thereof
02/05/2004WO2004011470A1 Furoisoquinoline derivative and use thereof
02/05/2004WO2004011438A1 Diaryl-substituted cyclic urea derivatives having an mch-modulatory effect
02/05/2004WO2002100886A8 Pyrrolidin-2-one derivatives as inhibitors of factor xa
02/05/2004US20040024399 Method for repairing damaged intervertebral discs
02/05/2004US20040024208 Cyclic protein tyrosine kinase inhibitors
02/05/2004US20040024190 Viral polymerase inhibitors
02/05/2004US20040024024 Inhibiting matrix metalloproteinase and aggrecanase activity; for treatment of strokes and neurodegenerative diseases
02/05/2004US20040023984 Compounds for the treatment of alzheimer's disease
02/05/2004US20040023947 Azepinoindole and pyridoindole derivatives as pharmaceutical agents
02/05/2004CA2493924A1 Diaryl-substituted cyclic urea derivatives having an mch-modulatory effect
02/04/2004EP1386946A1 4,7-dichlororhodamine dyes useful as molecular probes
02/04/2004EP1386912A1 Cyclic amidine derivative
02/04/2004EP1386317A1 Optical data carrier that contains a cyanine dye as the light-absorbing compound in the information layer
02/04/2004EP1386166A2 Anti-epileptogenic agents
02/04/2004EP1385846A2 Synthesis of pancratistatin prodrugs
02/04/2004EP1385843A1 Arylindenopyridines with pde inhibiting activity
02/04/2004EP1385836A2 Aromatic sulfone hydroxamates and their use as protease inhibitors
02/04/2004EP1385831A2 Pyrimidine compounds as anti-ictogenic and/or anti-epileptogenic agents
02/04/2004EP1155020B1 Furo[3,2-b]pyridines as 5-ht1f agonists
02/04/2004CN1473161A Pyrazole compounds as protein kinase inhibitors
02/04/2004CN1473150A Bis-heterocyclic compounds with antitumour and chemosensitising activity
02/04/2004CN1473045A Process for preparation of dinapsoline
02/04/2004CN1472213A High-performance camptothecin producing technology
02/04/2004CN1472208A Aromatic heterocyclic carboxylic acid derivative, preparing method and application in medicine
02/04/2004CN1137100C Tricyclic compounds capable of inhibiting tyrosine kinases of epidermal growth factor receptor family
02/04/2004CN1137097C Aminoalkyl-3,4-dihydroquindine derivates as No-synthase inhibitors
02/03/2004US6686470 Compounds of the saframycin-ecteinascidin series, uses, and synthesis thereof
02/03/2004US6686369 α-hydrdroxylic acid derivatives, their production and use
02/03/2004US6686348 Metalloprotease inhibitors
02/03/2004CA2182244C Camptothecin derivatives
01/2004
01/29/2004WO2004009092A1 Formulations and methods of administration of cephalotaxines, including homoharringtonine
01/29/2004WO2004009079A1 Chondropsin-class antitumor v-atpase inhibitor compounds, compositions and methods of use thereof
01/29/2004WO2004009036A2 Compounds compositions and methods
01/29/2004WO2004009030A2 Angiogenesis inhibition by cephalotaxine alkaloids, derivatives, compositions and uses thereof
01/29/2004WO2004009015A2 Combination therapy for the treatment of obesity
01/29/2004WO2003101996A3 Esters in position 20 of camptothecins
01/29/2004US20040019098 (3Z)-3-(2,3-dihydro-1H-inden-1-ylidene)-1,3-dihydro-2H-indol-2-ones as kinase inhibitors
01/29/2004US20040019079 Beta3-Adrenoreceptor agonists, agonist compositions and methods of using
01/29/2004US20040019071 Preferential opiate receptors, used as analgesics, antitussive agents, immunosuppressants or neuroprotectants; side effect reduction
01/29/2004US20040019070 Nitrogen compounds used as opiate receptor agonists or antagonists, for prophylaxis of drug abuse, cardiovascular, respiratory system, gastrointestinal disorders, as analgesics, antitussives or immunosuppressants
01/29/2004US20040019061 1-H-3-arylpirrolidine-2,4-dione derivatives
01/29/2004US20040019058 Chemokine receptor binding heterocyclic compounds with enhanced efficacy
01/29/2004US20040019056 Anititumoral analogs of et-743
01/29/2004US20040019051 Eating disorders of a disturbed or impaired fundus such as dyspepsia, early satiety, bloating and anorexia; e.g.,1-(1-((2,3-dihydro(1,4)dioxino(2,3-b)pyridin-3-yl)methyl) -4- piperidinyl)-2-imidazolidinone
01/29/2004US20040019041 Method for the production of imidazo-(1,2-C)(2,3)-benzodiazepines and intermediates in the production thereof
01/29/2004US20040019036 Treating a related myeloproliferative disorder or a Ph-positive acute lymphocytic leukemia; able to induce or to improve hematologic response and/or cytogenetic response and, eventually, survival, with a mild non-hematologic toxicity
01/29/2004US20040018988 Camptothecin derivatives having antitumor activity
01/29/2004US20040018239 Pharmaceutical preparation containing copolyvidone
01/29/2004CA2493544A1 Angiogenesis inhibition by cephalotaxine alkaloids, derivatives, compositions and uses thereof
01/29/2004CA2492456A1 Formulations and methods of administration of cephalotaxines, including homoharringtonine
01/29/2004CA2492225A1 Combination therapy for the treatment of obesity
01/28/2004EP1384737A2 Cycloaliphatic epoxy compounds containing styrenic, cinnamyl, or maleimide functionality
01/28/2004EP1384713A1 4-amino-azepan-3-one derivatives as protease inhibitors
01/28/2004EP1383772A2 Nitrogen-based camptothecin derivatives
01/28/2004EP1383771A1 9-deazaguanine derivatives as inhibitors of gsk-3
01/28/2004EP1383743A2 Dual inhibitors of pde 7 and pde 4
01/28/2004EP1383741A2 Process for the preparation of benazepril
01/28/2004EP1383507A1 Utilization of galanthamine for the treatment of pathologies of the central nervous system owing to intoxications with psychotropic substances
01/28/2004EP1383506A2 Fused heterocyclic inhibitors of phosphodiesterase (pde) 7
01/28/2004EP1383501A2 Acylated piperidine derivatives as melanocortin-4 receptor agonists
01/28/2004EP1383492A1 Molecular conjugates for use in treatment of cancer
01/28/2004EP1383490A1 Combination of epothilone analogs and chemotherapeutic agents for the treatment of proliferative diseases
01/28/2004EP1181335B1 Extended rhodamine compounds useful as fluorescent labels
01/28/2004CN1471536A Chemokine receptor antagonsis and method of use thereof
01/28/2004CN1471535A Tricyclic derivatives of indole with antiangiogenic activity
01/28/2004CN1470515A Method for extracting tetrodotoxin from globefish livers
01/28/2004CN1470514A Efficient method for refining tetrodotoxin by liquid-phase method
01/28/2004CN1470513A Total alkaloid with anticancer activity and its formulation
01/28/2004CN1135982C Process for preparing pharmaceutical composition containing N-acyl-2,3-benzodiazepine deriratives
01/27/2004USRE38408 Methods of preparing and purifying 9-nitro-20-camptothecin
01/27/2004US6683192 Substituted benzo(b)thien compounds useful for modulating proliferation or differentiation of a cell, agonizes hedgehog mediated signal trasnduction with an ed50 of 1mm or less
01/27/2004US6683142 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators
01/27/2004US6683105 Highly selective butyrylcholinesterase inhibitors such as cymserine or others can prevent or treat cognitive impairments associated with aging or alzheimer's disease
01/27/2004US6683099 Substituted N,N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity
01/27/2004CA2089464C N-heteroaryl-n'-(pyrid-2-yl-sulfonyl)ureas, processes for their preparation, and their use as herbicides and plant growth regulators
01/22/2004WO2004007510A1 Novel chemical substance having activity for morphogenesis and growth promotion
01/22/2004WO2004007504A1 Heterobicyclic pyrazole derivatives as kinase inhibitors
01/22/2004WO2004007503A1 Therapeutic or preventive agent for nausea/vomiting
01/22/2004WO2004007502A1 Furopyridine and furopyrimidine derivatives for the treatment of hyper-proliferative disorders
01/22/2004WO2004007458A1 Substituted 2-alkylamine nicotinic amide derivatives and use there of
01/22/2004WO2004007407A2 Fluorous tagging and scavenging reactants and methods of synthesis and use thereof
01/22/2004WO2003059911A3 4-OXO-4, 7-DIHYDROFURO[2,3-b]PYRIDINE-5-CARBOXAMIDE ANTIVIRAL AGENTS
01/22/2004WO2003055447A3 Heterocyclic acridone inhibitors of impdh enzyme
01/22/2004US20040014995 Chromene compounds
01/22/2004US20040014890 Cycloaliphatic epoxy compounds containing styrenic, cinnamyl, or maleimide functionality
01/22/2004US20040014784 Substituted propargylamines
01/22/2004US20040014755 Rho-kinase inhibitors
01/22/2004US20040014744 Anticancer, antitumor agents
01/22/2004US20040014743 Mbreast and prostate anticancer agents; viricides; alopecia
01/22/2004DE10231711A1 Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung Bicyclic heterocycles, pharmaceutical compositions containing them, their use and process for their preparation
01/22/2004CA2492694A1 Therapeutic or prophylactic agent for preventing nausea and vomiting
01/22/2004CA2492673A1 Heterobicyclic pyrazole derivatives as kinase inhibitors
01/22/2004CA2492100A1 Substituted 2-alkylamine nicotinic amide derivatives and use there of