Patents
Patents for C07D 471 - Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups (64,559)
08/1998
08/04/1998US5789587 Heterocyclic-fused lactams promote release of growth hormone
08/04/1998US5789434 Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors
08/04/1998US5789415 Azacyclic-heterocyclic compounds as angiotension II receptor antagonists
08/04/1998US5789402 Compounds having effects on serotonin-related systems
08/04/1998CA2119647C Heteroaryl amines as novel acetylcholinesterase inhibitors
07/1998
07/30/1998WO1998032802A1 Soluble chromophores having improved solubilising groups
07/30/1998WO1998032754A1 Imino-aza-anthracyclinone derivatives for the treatment of amyloidosis
07/30/1998WO1998032742A1 Novel amide derivatives and medicinal compositions thereof
07/30/1998CA2275965A1 Soluble chromophores having improved solubilising groups
07/29/1998EP0854869A1 Spiro compounds as inhibitors of fibrinogen-dependent platelet aggregation
07/29/1998EP0740668B1 Tetracyclic derivatives, process of preparation and use
07/29/1998EP0717732B1 Polyamidic acid derivatives with antigastrin activity, a method for their preparation, and their pharmaceutical use
07/29/1998EP0693068B1 Phenylpyrrole derivatives and their use as antipsychotic agents
07/29/1998EP0665846B1 Topoisomerase ii inhibitors and therapeutic uses therefor
07/29/1998EP0663913B1 New substituted pyrazole derivatives, processes for their preparation and their use as herbicides
07/29/1998CN1189165A Imidazo £1, 5 alpha| pyridine derived serine protease inhibitors
07/29/1998CN1188766A New ellipticine achroalkali compounds, process for their preparation and pharmaceutical compositions containing them
07/29/1998CN1039324C Substituted nitrogen heterocyclic pyrimidines compound preparation method of medicinal salt or N-oxide
07/29/1998CN1039323C Preparation method of imidazopyriding derivatives
07/28/1998US5786481 N-alkyl and N-acyl derivatives of 3,7-Diazabicyclo- 3.3.1!nonanes and selected salts thereof as multi-class antiarrhythmic agents
07/28/1998US5786480 4-substituted pyrazoloquinoline derivatives
07/28/1998US5786361 Antiatherosclerosic agents
07/28/1998US5786358 Inhibitors of glycinamide ribonucleotide formyl transferase
07/28/1998US5786353 Tricyclic benzazepine vasopressin antagonists
07/28/1998US5786352 Cyclic compounds, their production and use
07/28/1998CA2141563C Novel 2-substituted indane-2-mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase
07/28/1998CA2127561C 3-azabicyclohexane compound intermediates for producing antibacterial compounds
07/23/1998WO1998031364A1 3,3-disubstituted piperidines as modulators of chemokine receptor activity
07/23/1998WO1998031363A1 Anti-viral compounds
07/23/1998WO1998031359A1 Integrin antagonists
07/23/1998CA2278309A1 3,3-disubstituted piperidines as modulators of chemokine receptor activity
07/22/1998EP0854145A2 Vitronectin receptor antagonists, their production and their use
07/22/1998EP0854140A2 Vitronectin receptor antagonists, their production and their use
07/22/1998EP0853622A1 PROCESS FOR PREPARING 1-ARYL-4-OXOPYRROLO 3,2-c]QUINOLINE DERIVATIVES
07/22/1998EP0853477A1 At1-receptor antagonists for preventing and treating postischemic renal failure and for protecting ischemic kidneys
07/22/1998EP0725775B1 Certain fused pyrrolecarboxanilides; a new class of gaba brain receptor ligands
07/21/1998US5783723 Reacting an alkali metal alcoholate with an excess of dialkyl succinate under anhydrous conditions followed by isolation of the di(alkali metal) salt of the dialkyl succinylsuccinate; cyclization; neutralization
07/21/1998US5783708 Hexahydroisoindole derivatives
07/21/1998US5783594 Administering to treat glioma, colon cancer and immunological disordaers
07/21/1998US5783585 Solid bulk compositions containing quinolone carboxylic acids or naphthyridine carboxylic acids in free base form
07/21/1998US5783582 Piperidines and hexahydro-1H-azepines spiro substituted at the 4-position promote release of growth hormone
07/21/1998US5783579 Spiro-substituted azacyclic-substituted piperazino derivatives as neurokinin antagonists
07/16/1998WO1998030564A1 Sulfonamide derivatives
07/16/1998WO1998030562A1 Novel amide derivatives and intermediates for the synthesis thereof
07/16/1998WO1998030560A1 Quinoline and quinazoline compounds useful in therapy, particularly in the treatment of begnin prostatic hyperplasia
07/16/1998WO1998030558A2 Tricyclic compounds useful for inhibition of farnesyl protein transferase
07/15/1998EP0853085A1 Piperidine derivatives having anxiolytic effect
07/15/1998CN1039119C Condensed heterocyclic ketone derivatives, their production and use
07/14/1998US5780645 Procedure for alkylation of imides
07/14/1998US5780634 Decarboxylation
07/14/1998US5780633 Enzyme inhibitor of testosterone 5-alpha-reductase
07/14/1998US5780503 Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
07/14/1998US5780493 Treating brain disorders
07/14/1998US5780482 Condensed 4-aminopyridines with antirheumatic activity
07/14/1998US5780480 Thrombolytic agents, anticoagulants
07/14/1998US5780454 Boronic ester and acid compounds
07/09/1998WO1998029119A1 Inhibitors of farnesyl-protein transferase
07/09/1998CA2276150A1 Inhibitors of farnesyl-protein transferase
07/08/1998EP0851860A1 4-thiocarbamoyl-1-(3-pyrazolyl)-pyrazoles and their use as herbicides
07/08/1998EP0851756A1 5-ht 3? receptor antagonists for dyskinesia
07/08/1998CN1187129A Protein tyrosine kinase aryl and heteroaryl quinazoline compounds having selective inhibition of HER-2 autophosphorylation properties
07/08/1998CN1039010C Oxdiazolyl substituted naphthyridine derivatives, its intermediate, its preparation and its medicinal composition and its use in medicine
07/08/1998CN1039008C Dual action inhibitors in angiotensin invertase and neutral endopeptidase
07/07/1998USRE35840 Imidazo 1,5-a!quinolines for treatment of anxiety and sleep disorders
07/07/1998US5777114 Spiro heterocycle-imidazo 1,2-a!indeno 1,2-e!pyrazine!-4'-ones, preparation thereof and drugs containing same
07/07/1998US5776964 Hypotensive agents; anticholesterol agents; cardiovascular disorders
07/07/1998US5776963 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
07/07/1998US5776949 2-(1H) quinolinone compounds
07/07/1998US5776944 7-(4-aminomethyl-3-methyloxyiminopyrroplidin-1-yl)-1-cyclopropyl-6-flu oro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid and the process for the preparation thereof
07/07/1998US5776942 Bronchodilating pyrido 2,3-d!pyrimidine derivatives
07/07/1998US5776935 Antagonists of strychnine-insensitive glycine site of n-methylaspartic acid receptor
07/07/1998US5776930 Pharmaceutical preparation
07/02/1998WO1998028305A1 Novel counterparts of camptothecin, their application as medicine and pharmaceutical compositions containing them
07/02/1998WO1998028304A1 Pro-drugs and counterparts of camptothecin, their application as medicines
07/02/1998WO1998028297A1 Spiro-substituted azacyclic-substituted piperazino derivatives as neurokinin antagonists
07/02/1998WO1998028296A1 Pyrazol-based organic electroluminescent compounds and their use in electroluminescent devices
07/02/1998WO1998028281A1 Fused polycyclic 2-aminopyrimidine derivatives, their preparation and their use as protein tyrosine kinase inhibitors
07/02/1998WO1998027979A1 Heterocyclic inhibitors of microsomal triglyceride transfer protein and method
07/02/1998WO1998014445A3 Novel 6 or 7 substituted analogues of swainsonine, processes for their preparation and their use as therapeutic agents
07/02/1998CA2275163A1 Spiro-substituted azacyclic-substituted piperazino derivatives as neurokinin antagonists
07/01/1998EP0850940A1 Ellipticine derivatives, their preparation and pharmaceutical compositions containing them
07/01/1998EP0850939A1 Ellipticine derivatives, their preparation and pharmaceutical compositions containing them
07/01/1998EP0850236A1 Piperazino derivatives as neurokinin antagonists
07/01/1998EP0850060A1 Zwitterionic forms of trovafloxacin
07/01/1998EP0751945B1 PROCESS FOR PREPARING (1H-TETRAZOL-5-yl)TETRAZOLO 1,5-a] QUINOLINES AND NAPHTHYRIDINES
07/01/1998CN1186492A Imidazo £1, 2-alpha| pyridine derivatives
06/1998
06/30/1998US5773618 Tricyclic compounds having fungicidal activity, their preparation and their use
06/30/1998US5773530 Pyrazolopyridine adenosine antagonists
06/30/1998US5773456 Emphysema, rheumatoid arthritis and pancreatitis
06/30/1998US5773450 Fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles
06/30/1998US5773449 Thioquinolone compounds which have useful pharmaceutical activity
06/30/1998US5773436 Use of serotonin antagonists for treating fibromyalgia
06/30/1998CA2227506A1 New ellipticine derivatives, their preparation process and the pharmaceutical compositions containing them
06/25/1998WO1998027098A1 SUBSTITUTED NITROGEN CONTAINING HETEROCYCLES AS INHIBITORS OF p38 PROTEIN KINASE
06/25/1998WO1998027087A1 Combinatorial process for preparing fused pyrimidine libraries
06/25/1998WO1998027065A1 Modulators of proteins with phosphotyrosine recognition units
06/25/1998CA2275610A1 Modulators of proteins with phosphotyrosine recognition units
06/25/1998CA2274022A1 Combinatorial process for preparing fused pyrimidine libraries
06/24/1998CN1185782A 2-azabicyclo £2,2,1| heptane derivatives, preparation and application thereof
06/24/1998CN1185781A Fused polycyclic heterocycle derivatives