Patents
Patents for C07D 457 - Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula: , e.g. lysergic acid (836)
06/1993
06/15/1993US5219862 Dopaminergic agents
05/1993
05/26/1993EP0418327B1 Antiemesis ergoline derivatives
05/18/1993US5212178 Compounds for treatment of Parkinson*s Disease
05/11/1993US5210194 Anziolytic, antipsychotic and antiparkinson agents
04/1993
04/28/1993EP0538433A1 Agent suitable for transdermal administration containing ergolin derivatives
04/13/1993US5202325 Use of ergoline derivatives in treating emesis
02/1993
02/16/1993US5187164 Psychological disorders, antiemetics
02/03/1993EP0525145A1 Process for producing ergolin derivatives
01/1993
01/14/1993DE4123587A1 2,14-disubstituierte ergoline, deren herstellung und verwendung in arzneimitteln 2,14-disubstituted ergoline, their production and use in medicinal products
01/13/1993WO1993001185A1 2,14-disubstituted ergolines, their production and use in medicaments
01/13/1993CA2091455A1 2,14-disubstituted ergolines, their production and use in medicaments
01/07/1993WO1993000092A1 Improved process for the long term reduction of body fat stores, insulin resistance, hyperinsulinemia and hyperglycemia in vertebrates
12/1992
12/29/1992CA1312015C Antiparkinson ergoline derivatives
12/16/1992CN1019451B Cycioalkyliamides of (8beta)-1-alkyl-6-(substituted) ergolines
11/1992
11/26/1992WO1992020339A1 Agent suitable for transdermal administration containing ergolin derivatives
11/26/1992DE4116912A1 Mittel zur transdermalen applikation enthaltend ergolin-derivate Means for transdermal administration containing ergoline derivatives
10/1992
10/27/1992US5158957 2-substituted ergolines
08/1992
08/25/1992US5141944 Sexual dysfunction, hypotensive, antiischemic agents, headache, psychological disorders
08/20/1992WO1992013857A1 Process for producing ergolin derivatives
08/20/1992CA2080119A1 Process for the production of ergoline derivatives
07/1992
07/07/1992US5128345 Carcinostatic composition comprising indolquinolines
06/1992
06/24/1992CN1017154B Tetracyclic indole derivatives
06/02/1992CA1302405C Ergoline derivatives
06/02/1992CA1302404C .alpha.-ACYLAMINOERGOLINE, ITS PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING IT
05/1992
05/19/1992CA1301163C Process for the preparation of 2-halogenated ergoline derivatives
05/05/1992CA1300127C Process for preparing lysergol derivatives
04/1992
04/30/1992DE4034031A1 Prepn. of ergoline derivs. form corresp. N-oxide(s) - without use of toxic bromo:cyanide
04/29/1992EP0483063A1 Ergoline derivatives
04/21/1992CA2053712A1 Ergoline derivatives
03/1992
03/17/1992US5097031 Steroselective hydrogenation process
02/1992
02/25/1992CA1296324C Decyanation of pergolide intermediate
02/25/1992CA1296323C N-alkylation of dihydrolysergic acid
02/05/1992CN1015365B Process for the preparation of 2-halonicergoline derivatives and their acid addition salts and new 2-halonicergolines
01/1992
01/28/1992CA1294956C Production of 2-bromo-alpha-ergocryptine and its acid addition salts
01/07/1992US5079364 Treatment of senile dementia and cerebral insufficiency
01/02/1992EP0463139A1 2,13-disubstituted ergolins, their preparation and their use in drugs.
12/1991
12/31/1991US5077298 Administering neuroleptic agents
12/24/1991US5075318 For treating psychological disorders, Parkinson's disease
12/17/1991CA1293247C Ergoline derivatives
12/03/1991CA1292736C Ergoline derivatives and acid addition salts thereof
11/1991
11/27/1991EP0458640A2 Use of ergoline derivatives for the treatment of diseases associated with bone demineralization
11/27/1991CN1056496A Improvements in and relating to ergoline-8-carboxamides
11/26/1991CA2042960A1 Method of inhibiting demineralization of bone
11/19/1991CA1292224C Ergoline esters
11/19/1991CA1292223C Esters of dihydrolysergic acid and related compounds
11/07/1991DE4114230A1 Prepn. of 6H-ergoline derivs. - by cyanamide cleavage of corresp. 6-cyano cpd. using metallo:organic cpds.
11/05/1991US5063234 Method of inhibiting demineralization of bone
10/1991
10/31/1991DE4113609A1 Prepn. of 2- or 13-acyl-ergoline derivs. for pharmaceuticals - by acylation reaction in presence of lewis acid and opt. removing protecting gp.
10/22/1991CA1291121C 12- and 13-bromoergoline derivatives
10/22/1991CA1291120C Process for the production of ergoline derivatives
10/22/1991CA1291119C 2-substituted ergoline derivatives, processes for their preparation and use thereof as medicinal agents
10/16/1991EP0452074A2 Ergoline-8-carboxamides for blocking 5HT receptors
10/12/1991CA2040170A1 Ergoline-8-carboxamides
10/02/1991EP0449346A2 4-Piperidinyl-ergoline derivatives
10/01/1991CA1289948C 12- and 13-substituted ergoline derivatives
10/01/1991CA1289947C 1-alkyl ergolinylthiourea derivatives, process for the preparation thereof, as well as their use as medicinal agents
09/1991
09/17/1991CA1289143C Tetracyclic indole derivatives
08/1991
08/27/1991US5043341 N-(2-hydroxycyclopentyl)-1-isopropyl-6-methylergoline-8-carboxamides
08/17/1991WO1991012254A1 Substituted urea compounds and their preparation and use
08/17/1991CA2074803A1 Substituted urea compounds and their preparation and use
08/13/1991CA1287624C Ergolinyl heterocycles
08/07/1991EP0440333A2 Dopamine agonists for treating type II diabetes
08/07/1991CN1013446B N-alkylation of bihydrolysergic acid
08/06/1991US5037832 2-substituted ergolines
07/1991
07/26/1991WO1991011447A1 Process for preparing ergoline derivatives
07/26/1991CA2049053A1 Process for preparing ergoline derivatives
07/18/1991DE4001323A1 2,13-disubstituierte ergoline, deren herstellung und verwendung in arzneimitteln 2,13-disubstituted ergoline, their production and use in medicinal products
07/16/1991WO1991010663A1 2,13-disubstituted ergolins, their preparation and their use in drugs
07/16/1991CA2049016A1 2,13-disubstituted ergolines, their production and use in pharmaceutical agents
07/09/1991CA1285880C Use of terguride as a geriatric agent
06/1991
06/26/1991CN1012959B Process for preparation of benzodiazepine
06/25/1991CA1285277C Process for preparing ergoline derivatives
05/1991
05/29/1991EP0429153A1 Novel agroclavine and elymoclavine derivatives, processes for their preparation and their use in medicinal preparations
05/22/1991EP0427827A1 8-g(a)-ACYLAMINO-ERGOLINES, THEIR PREPARATION AND USE AS DRUGS.
05/21/1991CA2030340A1 Agroclavine and elymoclavine derivatives, process for their production and their use in pharmaceutical agents
04/1991
04/10/1991EP0420953A1 8-beta-substituted ergolines, a process for manufacturing them, and their use
03/1991
03/27/1991EP0418990A2 13-Bromo and 13,14-dibromo ergoline, their preparation and their use
03/21/1991CA2025744A1 13-bromo-and 13,14-dibromoergolines, their production and use in medicinal agents
02/1991
02/06/1991EP0411495A2 Ergoline derivatives of proline and related compounds having dopaminergic activity
02/06/1991EP0411494A2 Ergoline derivatives having dopaminergic activity
01/1991
01/24/1991DE4020341A1 Prodn. of 2-hydroxymethyl-ergoline derivs. - from ergoline derivs. and para-formaldehyde in presence of di:methyl-aluminium chloride
01/15/1991US4985424 Certain substituted 1,7-annelated 1h-indazoles being selective antagonists of 5-ht-receptors
12/1990
12/25/1990US4980475 Process for the preparation of N-10 alpha-methoxyl-lumilysergol and esters, thereof, and intermediates for their preparation
12/12/1990EP0401263A1 New ergoline derivatives, process for producing them and their use as drugs
11/1990
11/29/1990DE3917268A1 New ergoline di:ethyl-urea derivs.
11/13/1990WO1990013550A1 8α-ACYLAMINO-ERGOLINES, THEIR PREPARATION AND USE AS DRUGS
11/13/1990US4970314 Selective bromination with bromine in hydrogen bromide and halogenated hydrocarbon presence
11/13/1990CA2028832A1 8.alpha.-acylamino ergolines, their production and use as drugs
11/06/1990US4968801 Dehydrogenation with electrophilic reagent
10/1990
10/22/1990WO1990012796A1 8-beta-substituted ergolines, a process for manufacturing them, and their use
10/22/1990CA2031510A1 8beta-substituted ergolines, process for their production and their use
09/1990
09/26/1990EP0389068A2 2-Alkyl(or phenyl)thio-6-n-alkyl ergolines
08/1990
08/21/1990US4950759 Substituted 1,7-annelated 1H-indazoles
08/21/1990US4950672 Neuroleptic agents, hormone inhibitors/parkinson's disease
07/1990
07/25/1990EP0379308A1 Pharmaceutical compositions containing 1-isopropyldihydrolysergic acid
07/17/1990CA2007472A1 Method for selectively blocking 5ht2 receptors
07/11/1990CN1043715A Improvements in or relating to ergoline derivatives
07/03/1990US4939258 Cycloalkanol esters of dihydrolysergic acid
06/1990
06/27/1990EP0375297A2 Improvements in or relating to ergoline derivatives
06/19/1990CA2005506A1 Ergoline derivatives
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