Patents
Patents for C07D 457 - Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula: , e.g. lysergic acid (836)
06/2008
06/12/2008WO2008043601A3 Transdermal therapeutic system with two-phase releasing profile
05/2008
05/28/2008EP1925616A1 Process for the preparation of crystal forms of cabergoline via stable solvates of cabergoline
05/21/2008CN101184754A Ergoline derivatives and their use as chemokine receptor ligands
05/02/2008WO2008049884A1 Process for the preparation of crystal forms of cabergoline via novel stable solvates of cabergoline
04/2008
04/23/2008EP1912984A1 Solvate of cabergoline and preparations of cabergoline form i
04/17/2008WO2008043601A2 Transdermal therapeutic system with two-phase releasing profile
03/2008
03/05/2008EP1893611A1 Ergoline derivatives and their use as chemokine receptor ligands
03/04/2008US7339060 Form I; dissolving cabergoline in a p-disubstituted benzene to form a solvate, optionally adding a second solvent, crystallization; purification
02/2008
02/13/2008EP1147106B1 Process for the preparation of alkyl mercapto methyl ergoline derivatives
12/2007
12/20/2007US20070293677 Process for the Preparation of Cabergoline
12/05/2007EP1861398A2 Preparation of cabergoline
11/2007
11/28/2007EP1858894A1 Improved process for making cabergoline
10/2007
10/18/2007WO2007091039A3 Production of cabergoline and novel polymorphic form thereof
10/18/2007US20070244149 Tropane analogs and methods for inhibition of monoamine transport
09/2007
09/18/2007US7271171 Adenosine A3 receptor modulators
08/2007
08/23/2007US20070197576 Production of Cabergoline and Novel Polymorphic Form Thereof
08/21/2007US7258871 Combination of a transdermal therapeutic system and an oral and/or parenteral preparation containing dopamine agonists for the treatment of dopaminergic disease states
08/16/2007WO2007091039A2 Production of cabergoline and novel polymorphic form thereof
08/16/2007CA2640081A1 Production of cabergoline and novel polymorphic form thereof
08/09/2007DE10066158B4 Verwendung eines transdermalen therapeutischen Systems zur Behandlung des Restless-Legs-Syndroms Use of a transdermal therapeutic system for the treatment of Restless Legs Syndrome
07/2007
07/12/2007US20070161795 Process for isolation of ergot alkaloids from ergot
07/03/2007US7238810 Form I; dissolving cabergoline in 4-fluorotoluene to form a solvate, optionally adding a second solvent, crystallization; purification
06/2007
06/14/2007US20070135638 Process for the manufacture of lysergic acid
05/2007
05/31/2007US20070122859 Immunoassay for LSD and 2-oxo-3-hydroxy-LSD
05/15/2007US7217822 Ergoline-8. beta -carboxamide silylated by a silylation agent of general formula Y Si (R6)(R7)(R8), preferably with trimethylsilyl triflate, under presence of an organic amine
05/02/2007EP1311248B1 Transdermal therapeutic system for treating restless-legs-syndrome
05/02/2007CN1956985A Process for the manufacture of lysergic acid
04/2007
04/19/2007DE10212564B4 1-Allyl-ergotalkaloid-Derivate und ihre Verwendung zur Prophylaxe und Therapie von Migräne 1-allyl ergot alkaloid derivatives and their use for the prophylaxis and treatment of migraine
03/2007
03/07/2007EP1507777A4 Process for preparing crystalline form i of cabergoline
03/06/2007US7186837 Form I; dissolving cabergoline in ethylbenzene to form a solvate, optionally adding a second solvent, crystallization; purification
02/2007
02/14/2007CN1300139C Haptens, immunogens, antibodies and conjugates for 2-oxo-3-hydroxy LSD
02/01/2007WO2007012846A1 Solvate of cabergoline and preparations of cabergoline form i
02/01/2007CA2616738A1 Solvate of cabergoline and preparations of cabergoline form i
01/2007
01/04/2007WO2006100492A3 Preparation of cabergoline
01/02/2007US7157560 Antibody for use as diagnostic tool in immunoassays
12/2006
12/28/2006WO2006097345A9 Improved process for making cabergoline
12/27/2006EP1483264B1 1-allyl ergot alkaloid derivatives, method for producing the same and the use thereof for preventing and treating migraine
12/21/2006US20060287350 Process for making cabergoline
12/14/2006US20060281777 Process for preparing crystalline form I of cabergoline
12/07/2006WO2006128658A1 Ergoline derivatives and their use as chemokine receptor ligands
12/07/2006CA2608702A1 Ergoline derivatives and their use as chemokine receptor ligands
11/2006
11/15/2006EP1720869A2 Process for the preparation of cabergoline
11/08/2006EP1718644A1 Process for the manufacture of lysergic acid
10/2006
10/26/2006WO2006065448A3 Topoisomerase inhibitors and prodrugs
10/05/2006US20060223998 Synthetic LSD metabolite for preparing haptens used in an LSD metabolite immunoassay
10/03/2006US7115718 Haptens, immunogens, antibodies and conjugates to 2-oxo-3-hydroxy-LSD
09/2006
09/28/2006WO2006100492A2 Preparation of cabergoline
09/28/2006US20060217555 Preparation of cabergoline
09/28/2006US20060217408 Preparation of cabergoline
09/28/2006CA2602898A1 Preparation of cabergoline
09/21/2006WO2006097345A1 Improved process for making cabergoline
09/21/2006US20060211607 Somatostatin-dopamine chimeric analogs
09/07/2006US20060199838 3-hydroxy-N-(3-hydroxy-4-methoxyphenyl)-4-methoxybenzamide, used in the treatment of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and amyloidosis, such as observed non-insulin depepndent diabetes
07/2006
07/26/2006CN1809358A Polymorphs of cabergoline
07/26/2006CN1266149C Use of aspergillus fumigatus in preparing anti inflammatory immunosuppressant
05/2006
05/26/2006WO2006053899A1 Cabergoline preparation method
04/2006
04/11/2006US7026483 Forms of cabergoline
04/06/2006WO2005085243A3 Process for the preparation of cabergoline
03/2006
03/28/2006US7019140 Reduction and demethylation of quaternary ammonium salts with nucleophiles, e.g., an alkyl- or toluenesulfonyl halide, of an intemediate from 9,10-dihydrolysergic acid; followed by reacting with a sodium thiomethoxide; purity; efficiency; nontoxic; by-product inhibition
02/2006
02/01/2006EP1620101A2 Polymorphs of cabergoline
02/01/2006EP1620100A2 New forms of cabergoline
01/2006
01/19/2006US20060014774 1-allyl ergot alkaloid derivatives, methods for producing the same and the use thereof for preventing and treating migraine
11/2005
11/10/2005WO2005105796A1 Preparation of cabergoline
11/03/2005US20050245560 Form I; dissolving cabergoline in ethylbenzene to form a solvate, optionally adding a second solvent, crystallization; purification
11/02/2005EP1591445A1 Preparation of cabergoline form I und solvate therof
10/2005
10/11/2005US6953854 Process for preparing crystalline Form I of cabergoline
10/06/2005US20050220855 Matrix for administering ergoline compounds such as lisuride; restless leg syndrome; circadian rhythm disorders; Parkinson's disease
10/05/2005CN1221550C Crgstalline form II of cabergoline
09/2005
09/29/2005US20050214353 Matrix for administering ergoline compounds such as lisuride; restless leg syndrome; circadian rhythm disorders; Parkinson's disease
09/27/2005CA2068970C Agent for transdermal administration containing ergoline derivatives
09/15/2005WO2005085243A2 Process for the preparation of cabergoline
09/09/2005WO2005082902A1 Process for the manufacture of lysergic acid
09/09/2005CA2556774A1 Process for the manufacture of lysergic acid
07/2005
07/28/2005DE10043321B4 Verwendung eines transdermalen therapeutischen Systems zur Behandlung der Parkinsonschen Krankheit, zur Behandlung und Prävention des prämenstruellen Syndroms und zur Lactationshemmung Use of a transdermal therapeutic system for the treatment of Parkinson's disease, for the treatment and prevention of premenstrual syndrome and Lactationshemmung
07/21/2005US20050158240 Method for labeling with tritium
07/20/2005CN1642953A Process for preparing crystalline form I of cabergoline
07/20/2005CN1642926A Crystalline parecoxib sodium
07/13/2005CN1639160A Process for preparing crystalline form I of cabergoline
06/2005
06/23/2005WO2004101510B1 Polymorphs of cabergoline
06/14/2005CA2337669C Process for the preparation of alkyl mercapto methyl ergoline derivatives
06/09/2005US20050124812 Process for the synthesis of pergolide
05/2005
05/19/2005WO2004094368A3 New forms of cabergoline
05/12/2005WO2004101510A3 Polymorphs of cabergoline
04/2005
04/21/2005US20050085499 Crystal structure; solvates; parkinson's disease
02/2005
02/23/2005EP1507777A2 Process for preparing crystalline form i of cabergoline
02/09/2005CN1188412C Process for preparing crystalline form 1 of cabergoline
12/2004
12/15/2004EP1485383A1 Process for preparing crystalline form i of cabergoline
12/15/2004EP1485382A2 Process for the synthesis of pergolide
12/15/2004EP1485362A1 Crystalline parecoxib sodium
12/08/2004EP1483264A2 1-allyl ergot alkaloid derivatives, method for producing the same and the use thereof for preventing and treating migraine
12/08/2004CN1552710A Use of aspergillus fumigatus in antiflammation immunosuppressant
11/2004
11/25/2004WO2004101510A2 Polymorphs of cabergoline
11/25/2004CA2525104A1 Polymorphs of cabergoline
11/23/2004CA2125288C Serotoninergic ergoline derivatives
11/10/2004EP1280803B1 Crystalline form ii of cabergoline
11/04/2004WO2004094368A2 New forms of cabergoline
10/2004
10/21/2004US20040209910 Amorphous physical form of cabergoline substantially free of other physical forms, which is characterized by a given halo x-ray powder diffraction pattern; prepared from solvate form A of cabergoline
10/21/2004US20040209798 biodrugs for treatment of lung cancer, glioma, anorexia, hypothyroidism, hyperaldosteronism, H. pylori proliferation, acromegaly, restenosis, Crohn's disease, systemic sclerosis, external and internal pancreatic pseudocysts and ascites
10/06/2004EP1464644A1 Ergoline derivatives
10/05/2004US6800635 Crystallization from solvent at low temperature or slurrying procedure
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