| Patents for C07D 457 - Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula: , e.g. lysergic acid (836) |
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| 03/03/2015 | US8969374 Iso-ergoline derivatives |
| 02/03/2015 | US8946420 Neuromodulatory compounds |
| 11/25/2014 | US8895743 Methysergide derivatives |
| 10/14/2014 | US8859579 Compostions and methods for preventing and/or treating disorders associated with cephalic pain |
| 09/09/2014 | US8829021 Treatment of pediatric tumors |
| 07/31/2014 | WO2014114664A1 Process for producing 1, 4, 7, 10-tetraazacyclododecane-1, 4, 7, 10-tetraacetic acid and complexes thereof |
| 07/10/2014 | US20140194435 Novel substituted indolo 4,3 fg quinolines useful for treating migraine |
| 07/03/2014 | WO2014070971A3 Somatostatin-dopamine chimeric analogs |
| 07/01/2014 | US8765760 [1,2,4] triazol [1,5-a] pyrazines useful as inhibitors of phosphodiesterases |
| 06/26/2014 | WO2014100354A1 Novel methysergide derivatives |
| 06/26/2014 | US20140179706 Fluoroergoline derivatives and uses thereof |
| 05/28/2014 | CN103827113A 新型氟麦角碱类似物 The new fluorine ergot alkaloids like |
| 05/22/2014 | WO2014078857A1 Ergoline derivatives as dopamine receptor modulators |
| 04/30/2014 | EP2723735A1 Novel fluoroergoline analogs |
| 04/03/2014 | US20140094483 Novel iso-ergoline derivatives |
| 02/27/2014 | US20140058108 Lisuride, Terguride and Derivatives Thereof for Use in the Prophylaxis and/or Treatment of Fibrotic Changes |
| 02/06/2014 | US20140039188 Novel iso-ergoline derivatives |
| 12/26/2013 | US20130345253 Novel cabergoline derivatives |
| 10/15/2013 | CA2608702C Ergoline derivatives and their use as chemokine receptor ligands |
| 06/27/2013 | US20130165469 Novel neuromodulatory compounds |
| 06/20/2013 | US20130158064 Novel iso-ergoline derivatives |
| 06/19/2013 | CN103159756A Novel preparation method for nicergoline |
| 05/29/2013 | DE102010060382B4 Analysenverfahren zur Isolierung von Mykotoxinen mit einer Ergolin-Grundstruktur, insbesondere von Ergotalkaloiden Analysis method for the isolation of mycotoxins with a basic ergoline structure, in particular of ergot alkaloids |
| 12/27/2012 | WO2012177962A1 Novel fluoroergoline analogs |
| 12/27/2012 | CA2838991A1 Novel fluoroergoline analogs |
| 12/25/2012 | US8338445 Crystal form of cabergoline |
| 12/04/2012 | US8324386 Somatostatin-dopamine chimeric analogs |
| 11/14/2012 | CN102775402A Intermediate for preparation of dihydrolysergic acid and its preparation method |
| 10/24/2012 | CN102134239B Method of extracting high-purity lysergol from Ipomoea herderacea |
| 10/10/2012 | CN102718761A Preparation method for nicergoline |
| 07/25/2012 | EP2084158B1 Process for the preparation of crystal forms of cabergoline via novel stable solvates of cabergoline |
| 07/18/2012 | CN102596950A Deuterated compounds for electronic applications |
| 05/15/2012 | US8178651 Somatostatin-dopamine chimeric analogs |
| 03/22/2012 | WO2012001308A9 Method for synthesizing ergoline alkaloids from indolic bicyclic compounds by double cyclization, resulting materials, and intermediate materials |
| 03/20/2012 | CA2363067C Compounds and methods to inhibit or augment an inflammatory response |
| 01/05/2012 | WO2012001308A1 Method for synthesizing ergoline alkaloids from indolic bicyclic compounds by double cyclization, resulting materials, and intermediate materials |
| 11/16/2011 | EP2386565A2 Compounds and methods to inhibit or augment an inflammatory response |
| 09/20/2011 | CA2565440C Preparation of cabergoline form i from a solvate of cabergoline and ethylbenzene |
| 09/14/2011 | CN101781296B Method for producing nicergoline |
| 08/02/2011 | CA2449634C Somatostatin-dopamine chimeric analogs |
| 07/27/2011 | CN102134239A Method of extracting high-purity lysergol from Ipomoea herderacea |
| 07/20/2011 | EP2344488A1 Methods and kits for the determining the presence or absence of ergot alkaloids |
| 06/09/2011 | US20110137035 Preparation of microbiologically produced ergot alkaloids |
| 05/26/2011 | US20110124600 Use of Dopamine partial agonists for treament of the restless leg syndrome and corresponding pharmaceutical preparation |
| 05/19/2011 | WO2011059463A1 Deuterated compounds for electronic applications |
| 05/10/2011 | US7939665 reacting 6-(2-propenyl)-ergoline-8 beta -carboxylic acid with 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide in a halogenated solvent or anisole; prolactin inhibitors; industrial scale, cost-effective synthetic method; treating Parkinson's disease, Restless Legs Syndrome |
| 04/27/2011 | EP2313405A1 Preparation of microbiologically produced ergot alkaloids |
| 03/16/2011 | EP2294067A1 Preparation of n-6 demethylated, 9-10-dihydrolysergic acid alkyl esters |
| 03/08/2011 | CA2376703C Method for preparing lysergic acid |
| 12/28/2010 | US7858791 high yield, milder reaction conditions and a shorter reaction time; easier purification by normal phase chromatography if needed; cabergoline is a dopamine agonist, a drug for treating Parkinson's disease |
| 12/22/2010 | CN101184754B Ergoline derivatives and their use as chemokine receptor ligands |
| 07/21/2010 | CN101781296A Method for producing nicergoline |
| 07/15/2010 | US20100179304 Somatostatin-Dopamine Chimeric analogs |
| 06/17/2010 | US20100152223 Crystal form of cabergoline |
| 05/27/2010 | DE102007014947B4 Stabilisierte wässrige Lösungen von Ergolinverbindungen The stabilized aqueous solutions of ergoline compounds |
| 05/26/2010 | EP1720869B1 Process for the preparation of cabergoline |
| 05/11/2010 | US7714132 Tetrahydropyridoindole derivatives |
| 04/22/2010 | WO2010045527A1 Methods and kits for the determining the presence or absence of ergot alkaloids |
| 02/23/2010 | US7666877 Ergoline derivatives |
| 01/07/2010 | WO2010000676A1 Preparation of microbiologically produced ergot alkaloids |
| 01/06/2010 | EP2141165A1 Processing microbiologically produced ergot alkaloids |
| 12/23/2009 | EP2135869A1 Preparation of a crystalline form of cabergoline |
| 12/15/2009 | US7632948 reacting 8-amino-1,2,3,4-tetrahydro-isoquinoline with chloral hydrate and hydroxylamine hydrochloride to give an N-(1,2,3,4-tetrahydro-isoquinolin-8-yl)-2-hydroxyimino-acetamide, adding H2SO4 to provide a 2,3-dioxo-2,3,6,7,8,9-hexahydro-1H-pyrrolo[3,2-h]isoquinoline, finally reacting with butyrolactone |
| 11/24/2009 | US7622476 1-allyl-( 5R,8S,10R)-terguride; antagonistic properties to 5-HT2 receptors for the prevention of migraine-related headache, Parkinson's disease, disorders of the thrombocyte function |
| 11/17/2009 | US7618979 Prostaglandin receptor antagonists; allergic rhinitis, nasal congestion and asthma; [5-[(4-chlorophenyl)thio]-4-(methylsulfonyl)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-6-yl]acetic acid |
| 11/05/2009 | WO2009133097A1 Preparation of n-6 demethylated, 9-10-dihydrolysergic acid alkyl esters |
| 11/05/2009 | US20090275501 Somatostatin-dopamine chimeric analogs |
| 11/04/2009 | EP2113504A1 Preparation of N-6 demethylated, 9,10-dihydrolysergic acid alkyl esters |
| 10/22/2009 | US20090264456 Compostions and methods for preventing and/or treating disorders asociated with cephalic pain |
| 10/07/2009 | EP1311249B1 Set of transdermal therapeutic systems |
| 09/24/2009 | WO2009071607A3 Ergoline derivatives as selective radical scavengers for neurons |
| 08/25/2009 | US7579435 Somatostatin-dopamine chimeric analogs |
| 08/13/2009 | WO2008104956A3 Process for the preparation of amorphous cabergoline |
| 08/11/2009 | US7572883 Somatostatin-dopamine chimeric analogs |
| 08/05/2009 | EP2084158A1 Process for the preparation of crystal forms of cabergoline via novel stable solvates of cabergoline |
| 07/30/2009 | WO2008049884A8 Process for the preparation of crystal forms of cabergoline via novel stable solvates of cabergoline |
| 07/29/2009 | EP2083008A1 Ergoline derivatives as selective radical scavengers for neurons |
| 07/28/2009 | US7566549 Using hapten derivatives for the preparation of antigens, antibodies and reagents for use detecting lysergic acid diethylamide (LSD) in samples; hallucinogen |
| 07/22/2009 | EP2079458A2 Transdermal therapeutic system with two-phase releasing profile |
| 07/21/2009 | CA2478393C 1-allyl ergot alkaloid derivatives, methods for their production and their use for migraine prevention and treatment |
| 07/15/2009 | CN101481405A Somatostatin-dopamine chimeric analogs |
| 06/11/2009 | WO2009071607A2 Ergoline derivatives as selective radical scavengers for neurons |
| 06/10/2009 | EP2067780A1 Ergoline derivatives as selective radical scavengers for neurons |
| 05/27/2009 | EP2062914A2 Somatostatin-dopamine chimeric analogs |
| 05/12/2009 | US7531551 Polymorphs of cabergoline |
| 03/11/2009 | CN101384589A Production of cabergoline and novel polymorphic form thereof |
| 03/04/2009 | EP1401863B1 Somatostatin-dopamine chimeric analogs |
| 01/15/2009 | US20090018127 (6aR,9R)-9-(Pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxylic acid phenylamide; preventing or treating disorders or diseases mediated by chemokine receptors; antiinflammatory agents treating inflammatory or autoimmune diseases; chemical preparation |
| 12/31/2008 | EP2007761A2 Production of cabergoline and novel polymorphic form thereof |
| 11/19/2008 | EP1485382B1 Process for the synthesis of pergolide |
| 11/13/2008 | WO2007091039A8 Production of cabergoline and novel polymorphic form thereof |
| 11/06/2008 | US20080275240 reacting 6-(2-propenyl)-ergoline-8 beta -carboxylic acid with 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide in a halogenated solvent or anisole; prolactin inhibitors; industrial scale, cost-effective synthetic method; treating Parkinson's disease, Restless Legs Syndrome |
| 11/05/2008 | EP1303278B1 Combination of a transdermal therapeutic system and an oral and/or parenteral preparation containing dopamine agonists for the treatment of dopaminergic disease states |
| 11/04/2008 | CA2587880A1 A new and efficient process for the preparation of cabergoline and its intermediates |
| 09/25/2008 | DE102007014947A1 Stabilisierte wässrige Lösungen von Ergolinverbindungen The stabilized aqueous solutions of ergoline compounds |
| 09/04/2008 | WO2008104956A2 Process for the preparation of amorphous cabergoline |
| 08/07/2008 | WO2008092881A1 New crystal form of cabergoline |
| 08/06/2008 | EP1953157A1 New crystal form of cabergoline |
| 07/23/2008 | CN101228159A Solvate of cabergoline and preparations of cabergoline form i |
| 06/25/2008 | CN101208337A Preparation of cabergoline |