Patents
Patents for C07D 457 - Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula: , e.g. lysergic acid (836)
03/2001
03/20/2001CA2211385C N-1-carboxyalkyl derivatives of lsd
02/2001
02/07/2001EP0830370B1 N-1-carboxyalkyl derivatives of lsd
01/2001
01/11/2001WO2001002395A1 Method for preparing lysergic acid
08/2000
08/17/2000WO2000047571A1 Piperidine and piperazine derivatives as inhibitors of the abeta fibril formation
08/17/2000CA2362389A1 Piperidine and piperazine derivatives as inhibitors of the abeta fibril formation
08/16/2000EP1027889A2 Ergolin derivates for transdermal application
08/03/2000WO2000044748A1 Process for the preparation of alkyl mercapto methyl ergoline derivatives
07/2000
07/20/2000WO2000042071A2 Compounds and methods to inhibit or augment an inflammatory response
07/20/2000CA2697598A1 Compounds and methods to inhibit or augment an inflammatory response
07/12/2000CN1259946A Ergoline derivatives and their use as somatostatin receptor antagonists
07/11/2000US6087371 Treating central nervous system disorders associated with serotoninergic disfunctions, such as impairment of thermoregulation, memory function, sleep disorders, satiety control (i.e. food and beverage consumption)
06/2000
06/02/2000WO2000030644A1 Novel therapeutic use of 1,6-dimethyl-8beta-hydroxymethyl-10alpha-methoxyergoline
06/02/2000WO2000030643A1 Novel therapeutic application of nicergoline
05/2000
05/16/2000US6063908 Reagents for lysergic acid diethylamide immunoassay
05/09/2000US6060483 Ergoline derivatives
03/2000
03/22/2000EP0986558A2 Ergoline derivatives and their use as somatostatin receptor antagonists
01/2000
01/27/2000WO2000004018A1 Ergoline amine derivatives with blood pressure lowering effect
01/27/2000DE19832191A1 New N-acylated ergoline amine derivatives, are alpha-1 adrenoreceptor blockers useful as potent, well tolerated antihypertensive agents
01/27/2000CA2337881A1 Novel ergoline amine derivatives and their use
08/1999
08/26/1999WO1999042840A1 Immunoassays for determination of lsd and lsd metabolites
06/1999
06/02/1999EP0593692B1 Process for the preparation of ergoline derivatives
05/1999
05/26/1999EP0917874A1 Process for the long term reduction of body fat stores, insulin resistance, hyperinsulinemia and hypoglycemia in vertebrates
05/05/1999CN1043230C Serotoninergic ergoline derivs.
04/1999
04/14/1999EP0907651A1 Antineurodegenerative ergoline derivatives
03/1999
03/17/1999CN1211253A Heterocyclyl-ergoline derivatives as 5-HT1A receptor ligands
03/04/1999WO1998054183A3 Ergoline derivatives and their use as somatostatin receptor antagonists
02/1999
02/02/1999US5866584 Administration of a dopamine agonist, over a limited period at a time of day dependent on the normal circadian rhythm of insulin resistant and insulin sensitive members of a similar species.
12/1998
12/29/1998US5854255 Therapeutic package for the long term reduction of body fat stores insulin resistance hyperinsulinemia and hyperglycemia in vertebrates
12/23/1998EP0885222A1 Heterocyclyl-ergoline derivatives as 5-ht1a receptor ligands
12/03/1998WO1998054183A2 Ergoline derivatives and their use as somatostatin receptor antagonists
12/03/1998CA2288810A1 Ergoline derivatives and their use as somatostatin receptor antagonists
12/01/1998US5843682 N-1-carboxyalkyl derivatives of LSD
10/1998
10/28/1998CN1040438C One-pot process for preparing sulfur propyl ergoline
07/1998
07/08/1998CN1186663A Process for preparing pharmaceutical formulation containing ergoline-8-carboxamides derivatives
07/01/1998CN1038937C Preparation of ergoline-8-carboxamides
05/1998
05/27/1998CN1038510C Process for the synthesis of ergoline derivatives
05/12/1998US5750519 Administering dopamine antagonist and prolactin stimulator
04/1998
04/14/1998US5739146 Substituted cyclo or bicycloalkylamides of (8β)-6-(substituted) ergolines
03/1998
03/25/1998EP0830370A1 N-1-carboxyalkyl derivatives of lsd
03/24/1998US5731312 Administering mixture of dopamine antagonist and prolactin inhibitor
02/1998
02/17/1998US5719160 Method for modifying and regulating lipid metabolism
02/10/1998US5716957 Administering a hypoglycemic agent or dopaminergic agent once a day and within two hours after waking in morning
02/10/1998CA1339661C Cycloalkylamides of (8b)-1alkyl-6 (substituted)ergolines
01/1998
01/08/1998WO1998000424A1 Antineurodegenerative ergoline derivatives
01/08/1998CA2258627A1 Antineurodegenerative ergoline derivatives
01/07/1998EP0816364A1 Reagents for lysergic acid diethylamide immunoassay
12/1997
12/16/1997CA1339584C 2-substituted ergolines, their production and use
11/1997
11/11/1997CA1339533C T-butyl ergoline derivatives
09/1997
09/30/1997CA2019407C Stereoselective hydrogenation process
08/1997
08/21/1997WO1997030050A1 Heterocyclyl-ergoline derivatives as 5-ht1a receptor ligands
08/21/1997CA2243992A1 Heterocyclyl-ergoline derivatives as 5-ht1a receptor ligands
08/05/1997US5654313 Administering a prolactin-inhibiting compound and subsequently a prolactin-stimulating compound
07/1997
07/30/1997EP0515537B1 Substituted urea compounds and their preparation and use
06/1997
06/03/1997US5635512 Method for modifying or resetting the prolactin rhythm of an insulin insensitive or diabetic animal or human
05/1997
05/29/1997WO1997019100A1 N-1-carboxyalkyl derivatives of lsd
05/20/1997CA2112355C Improved process for the long term reduction of body fat stores, insulin resistance, hyperinsulinemia and hyperglycemia in vertebrates
01/1997
01/15/1997EP0427827B1 8-alpha-ACYLAMINO-ERGOLINES, THEIR PREPARATION AND USE AS DRUGS
12/1996
12/24/1996CA2030174C Process for the long term reduction of body fat stores, insulin resistance, hyperinsulinemia and hypoglycemia in vertebrates
10/1996
10/23/1996CN1134158A N-alkyl peptide chelate formers, their metal complexes with radionuclides, processes for producing them and radio-pharmaceutical compositions contg. these compounds
09/1996
09/10/1996US5554623 Method for the long term reduction of body fat stores, insulin resistance, hypersinsulinemia and hyperglycemia in vertebrates
08/1996
08/21/1996EP0726909A1 N-alkyl peptide chelate formers, their metal complexes with radionuclides, processes for producing them and radio-pharmaceutical compositions containing these compounds
08/20/1996US5547958 Parkinson's disease
03/1996
03/05/1996US5496803 Administering prolactin by itself or with a glucosteroid such as cortisol
01/1996
01/30/1996CA2001004C Antiemesis ergoline derivatives
01/02/1996US5480885 Ergoline derivatives of 1-propinylamine, a process for the manufacture thereof and the use thereof for medicaments
12/1995
12/06/1995EP0464178B1 Process for preparing ergoline derivatives
11/1995
11/09/1995WO1995029912A1 Ergoline derivatives as analgesics
10/1995
10/31/1995US5463060 One-pot process
08/1995
08/15/1995US5441961 Substituted cyclo or bicycloalkylamides of (8β)-6-(substituted) ergolines
07/1995
07/12/1995EP0463139B1 2,13-disubstituted ergolins, their preparation and their use in drugs
07/04/1995US5430031 Serotoninergic ergoline derivatives
05/1995
05/11/1995WO1995012610A1 N-alkyl peptide chelate formers, their metal complexes with radionuclides, processes for producing them and radio-pharmaceutical compositions containing these compounds
05/11/1995CA2173844A1 N-alkyl peptide chelate formers, their metal complexes with radionuclides, processes for producing them and radio-pharmaceutical compositions containing these compounds
05/02/1995US5411966 2, 13-disubstituted ergolines, their production and use in pharmaceutical agents
03/1995
03/30/1995DE4333287A1 Fluorinated ergolines
03/28/1995US5401748 2,14-disubstituted ergolines, their production and use in pharmaceutical compositions
03/21/1995US5399355 Uniform penetration through skin
01/1995
01/17/1995US5382669 Process for the preparation of ergoline derivatives
12/1994
12/14/1994EP0628042A1 Serotoninergic ergoline derivatives
12/06/1994US5371000 Process for the production of ergoline derivatives
10/1994
10/05/1994CN1093087A Serotoninergic ergoline derivatives
09/1994
09/06/1994US5344832 Administering dopamine agonist and prolactin stimulator
08/1994
08/02/1994US5334385 New alkaloid derivatives, their use and pharmaceutical formulations containing them
07/1994
07/07/1994WO1994014806A1 Serotoninergic ergoline derivatives
04/1994
04/27/1994EP0593692A1 Process for the preparation of ergoline derivatives
04/13/1994EP0591458A1 Improved process for the long term reduction of body fat stores, insulin resistance, hyperinsulinemia and hyperglycemia in vertebrates
03/1994
03/01/1994US5290795 Substituted urea compound and use
02/1994
02/23/1994CN1082544A One-pot process
02/22/1994US5288724 Antiserotonine agents, hypotensive agents, antidepressants
02/15/1994EP0591458A4 Improved process for the long term reduction of body fat stores, insulin resistance, hyperinsulinemia and hyperglycemia in vertebrates.
12/1993
12/08/1993EP0573260A1 New alkaloid derivatives, their use and pharmaceutical formulations containing them
12/08/1993CN1023014C Process for preparing ergoline derivatives
11/1993
11/24/1993EP0571202A1 One-pot process for preparing pergolide
10/1993
10/06/1993EP0564193A1 Heteroannulation process
10/04/1993CA2092782A1 Heteroannulation process
09/1993
09/16/1993WO1993018034A1 Process for the preparation of ergoline derivatives
09/15/1993CN1076196A Process for the synthesis of ergoline derivatives
09/07/1993US5242678 BR*-diagnostics for monoamine receptors
06/1993
06/30/1993EP0548327A1 2,14-disubstituted ergolines, their production and use in medicaments
06/29/1993CA1319684C Ergolinyl compounds nitrogen-substituted in the 8- position, their preparation, and use as medicinal agents
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