Patents
Patents for C07D 401 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom (107,979)
08/2008
08/21/2008US20080200516 Solid state forms of racemic ilaprazole
08/21/2008US20080200515 Solid state forms of enantiopure ilaprazole
08/21/2008US20080200509 Utilizing such as 4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-ylamide against cancer growth
08/21/2008US20080200505 Piperidines for the Treatment of Chemokine Mediated Diseases
08/21/2008US20080200503 Bioavailable formulations with ritonavir; potency, decreased cytotoxicity, improved pharmacokinetics; N-[18-[2-(4-isopropylthiazol-2-yl)-7-methoxyquinolin-4-yl-oxy]-2,15-dioxo- -3,14,16-triazatricyclo[14.3.0.0.sup.4,6]nonadec-7-ene-4-carbonyl]-(cyclopropyl)sulfonamide
08/21/2008US20080200497 inhibitors of the hepatitis C virus NS3 protease; azalactone intermediate reacted with cycloalkylsulfonamide and decylization; urea or carbamate-terminated alkylglycine. hydroxyproline, cyclopropylglycine tripeptide
08/21/2008US20080200496 SUBSTITUTED 1H-PYRROLO[3,2-b, 3,2-c, and 2,3-c]PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE Ie
08/21/2008US20080200487 Prepared by reacting free base with an acid in methanol under a nitrogen atmosphere; use in treating a disease which responds to an inhibition of protein kinase activity
08/21/2008US20080200476 Alaphatic pyrazinoylguanidine sodium channel blockers
08/21/2008US20080200469 Phthalazinone derivatives
08/21/2008US20080200468 2-Substituted 5-Membered Heteroaryl Carboxylates as Hm74a Receptor Agonists
08/21/2008US20080200465 Antipathogenic benzamide compounds
08/21/2008US20080200464 Use treating hepatocyte growth factor (HGF)-mediated diseases such as cancer; inhibitors of c-Met; e.g. 3-(3-fluoro-4-(7-methoxyquinolin-4-yloxy)phenylamino)-N-phenylpyrazine-2-carboxamide
08/21/2008US20080200463 N-[5-(5-formyl-2-thienyl)-4-methyl-1,3-thiazol-2-yl]acetamide; autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer
08/21/2008US20080200462 Substituted pyrazole and triazole compounds as ksp inhibitors
08/21/2008US20080200460 Chemical Compounds
08/21/2008US20080200448 New Pyridine Analogues VIII 518
08/21/2008US20080200445 Heterocyclic aspartyl protease inhibitors
08/21/2008US20080200431 Heterocyclic Sulfonamide Derivatives as Inhibitors of Factor Xa
08/21/2008US20080199973 sulfoalkyl substituents and/or hydrophilic linkers derived from homocysteic acid, cysteic acid, glycine peptides, tetraethylene oxide offset hydrophobicity of the acridinium ring system for a more soluble label attached to an antibody at higher loading to prevent protein precipitation and aggregation
08/21/2008US20080199875 Unsymmetrical cyanine dimer compounds and their application
08/21/2008US20080199459 Mitotic Kinesin Inhibitors
08/21/2008US20080199422 Method for the Treatment of Myelodysplastic Syndromes Using 1-Oxo-2-(2,6-Dioxopiperidin-3-Yl-)-4-Methylisoindoline
08/21/2008DE102007007751A1 Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel New substituted Arylsulfonylglycine, their preparation and their use as medicaments
08/21/2008CA2679849A1 Functionally selective alpha2c adrenoreceptor agonists
08/21/2008CA2678382A1 New substituted arylsulphonylglycines, the preparation thereof and the use thereof as pharmaceutical compositions
08/21/2008CA2678036A1 Functionally selective alpha2c adrenoreceptor agonists
08/21/2008CA2677736A1 Fused ring compounds as partial agonists of ppar-gamma
08/21/2008CA2676906A1 Novel inhibitors hepatitis c virus replication
08/21/2008CA2676715A1 Piperazine derivatives for treatment of ad and related conditions
08/21/2008CA2674100A1 Use of neuroprotective compounds for obtaining drugs for treating neurodegenerative diseases
08/21/2008CA2674087A1 6' substituted compounds having 5-ht6 receptor affinity
08/21/2008CA2673534A1 2-anilino-4-heteroaryl pyrimidine derivatives, and preparation thereof as medicaments, pharmaceutical compositions, and in particular ikk inhibitors
08/21/2008CA2673532A1 New phenyl-(4-phenyl-pyrimidin-2-yl)-amines derivatives, preparation thereof as drugs, pharmaceutical compositions and use thereof essentially as ikk inhibitors
08/21/2008CA2672959A1 New n, n'- 2,4-dianilinopyrimidine derivatives, preparation thereof as drugs, pharmaceutical compositions essentially as ikk inhibitors
08/21/2008CA2672955A1 New 2, 4-dianilinopyrimidines, preparation thereof as drugs, pharmaceutical compositions and use thereof essentially as ikk inhibitors
08/20/2008EP1958947A1 Inhibitors of phosphodiesterase type 4
08/20/2008EP1958946A1 Pyridazine compound and use thereof
08/20/2008EP1958934A1 Tetrahydronaphthalenylamides, a process for their production and their use as anti-inflammatory agents
08/20/2008EP1957483A1 Novel vinylogous acids derivatives
08/20/2008EP1957480A1 Substituted oxindol-derivatives, medicaments containing said derivatives and use thereof
08/20/2008EP1957479A2 1,5-substituted indol-2-yl amide derivatives
08/20/2008EP1957478A2 New compounds
08/20/2008EP1957477A1 1h-benzimidazole-4-carboxamides substituted with phenyl at the 2-position are potent parp inhibitors
08/20/2008EP1957476A1 L-alanine derivatives
08/20/2008EP1957469A1 Antiproliferative pyrimidyl, fused pyrimidyl and pyrimidyl hydrazones
08/20/2008EP1957466A1 4-aminopyrimidine-5-thione-derivatives for the treatment of cancer
08/20/2008EP1957462A2 Novel 2-amino-heterocycles udeful in the treatment of abeta-related pathologies
08/20/2008EP1957461A1 Bisamide inhibitors of hedgehog signaling
08/20/2008EP1957460A1 Bicyclic compounds with kinase inhibitory activity
08/20/2008EP1957449A1 Compounds for the treatment of inflammatory disorders and microbial diseases
08/20/2008EP1957075A2 Novel m3 muscarinic acetylcholine receptor antagonists
08/20/2008EP1957058A1 Compounds for the treatment of inflammatory disorders and microbial diseases
08/20/2008EP1778632B1 Indoles useful in the treatment of inflammation
08/20/2008EP1692129B1 Keto lactam compounds and use thereof
08/20/2008EP1685102A4 Melanocortin receptor agonists
08/20/2008EP1670790B1 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
08/20/2008EP1670770B1 Benzimidazole derivatives, compositions containing them, preparation therof and uses thereof
08/20/2008EP1660492B1 Benzimidazole, benzthiazole and benzoxazole derivatives and their use as lta4h modulators
08/20/2008EP1569647B1 Cyclohexyl compounds as ccr5 antagonists
08/20/2008EP1404653B1 Triamide-substituted indoles, benzofuranes and benzothiophenes as inhibitors of microsomal triglyceride transfer protein (mtp) and/or apolipoprotein b (apo b) secretion
08/20/2008EP1337251B1 Monocyclic or bicyclic carbocycles and heterocycles as factor xa inhibitors
08/20/2008EP1318993B1 Substituted imidazoles as dual histamine h1 and h3 agonists or antagonists
08/20/2008CN101248070A 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
08/20/2008CN101248059A Substituted amide derivatives as protein kinase inhibitors
08/20/2008CN101248058A 1, 3, 5-triazine derivative, method for producing the same and organic electroluminescent device comprising the same as constituent
08/20/2008CN101248049A 咪唑类lxr调节剂 Imidazole lxr modifier
08/20/2008CN101248048A Imidazole based LXR modulators
08/20/2008CN101248046A Amide derivatives as kinase inhibitors
08/20/2008CN101248044A Novel indole compounds
08/20/2008CN101247877A Hindered cyclic polyamines and their salts for acid gas scrubbing process
08/20/2008CN101247853A Substituted indole compounds having NOS inhibitory activity
08/20/2008CN101245097A Inhibitors of serine proteases, particular hcv NS3-NS4 protease
08/20/2008CN101245062A Tetrahydroquinoline compound, preparation method and pharmaceutical composition
08/20/2008CN101245061A N-(5-amido-2-methyl phenyl)-4-(3-pyridinyl)-2-aminopyrimidine nitric oxide donating derivant, production method and uses thereof
08/20/2008CN100412075C Process for preparing L-ofloxacin and ofloxacin
08/19/2008US7414135 halide salt of a 1-(hydroxyiminomethyl-1-pyridino)-3-(halomethyl)-2-oxapropane is prepared by adding a pyridinealdoxime to a bis-halomethylether in such a manner that the bis-halomethylether is maintained in excess throughout the addition
08/19/2008US7414132 prophylaxis and treatment of obesity; secondary amines such as 6-{4-[(3-Methyl-butylamino)-methyl]-phenoxy}-nicotinimidic acid ethyl ester
08/19/2008US7414067 Ophthalmic compositions for treating ocular hypertension
08/19/2008US7414066 Anticholesterol agents; antilipemic agents; antiischemic agents; cardiovascular disorders
08/19/2008US7414065 Methods to modulate conditions mediated by the CXCR4 receptor
08/19/2008US7414064 Pesticides for crops; agriculture, horticulture
08/19/2008US7414062 such as 5-[8-(3-dimethylcarbamoyl-3,3-diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-3-yl]-pentanoic acid; non-opioid analgesic; side effect reduction; for stimulating opioid receptors
08/19/2008US7414060 Pyridine-2-carboxyamide derivatives
08/19/2008US7414057 Piperazine urea derivatives as melanocortin-4 receptor agonists
08/19/2008US7414056 Cytokine inflammatory response suppressors; mitogen activated protein 38 kinases
08/19/2008US7414055 Inhibitors of Akt activity
08/19/2008US7414054 3-(arylamino)methylene-1, 3-dihydro-2H-indol-2-ones as kinase inhibitors
08/19/2008US7414047 Piperazinyl and diazapanyl benzamides and benzthioamides
08/19/2008US7414046 Gyrase inhibitors and uses thereof
08/19/2008US7413727 Contrast agents
08/19/2008CA2461567C Substituted pyrazolyl benzenesulfamide compounds for the treatment of inflammation
08/19/2008CA2432799C Pyrazole compounds useful as protein kinase inhibitors
08/19/2008CA2257448C Pyridyl alkene- and pyridyl alkine-acid amides as cytostatics and immunosuppressives
08/19/2008CA2200871C Aniline derivatives
08/14/2008WO2008098058A1 Pi 3-kinase inhibitors and methods of their use
08/14/2008WO2008097976A1 Heterocyclic modulators of tgr5 for treatment of disease
08/14/2008WO2008097428A2 Compounds and compositions as modulators of gpr119 activity
08/14/2008WO2008096987A1 Novel imatinib camsylate and method for preparing thereof
08/14/2008WO2008096791A1 Acylguanidine derivative