| Patents for C07D 401 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom (107,979) |
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| 09/09/2008 | US7423052 Piperidine compounds for use as orexin receptor antagoinst |
| 09/09/2008 | US7423051 e.g. [2-Amino-6-(1-methanesulfonyl-piperidin-4-ylamino)-pyridin-3-yl]-(2-methoxy-phenyl)-methanone; inhibit cyclin-dependent kinases; cell cycle from G1 to S phase; antiproliferative, anticarcinogenic agent; solid tumors |
| 09/09/2008 | US7423050 2,4,6-trifluoro-N-[6-[(1-methyl-4-piperidinyl)carbonyl]-2-pyridinyl]-benzamide (hemisuccinate/hydrochloride salt); migraine; inhibit peptide extravasation, while avoiding significant vasoconstrictive activity; improved solubility |
| 09/09/2008 | US7423049 e.g., 2-(5-fluoro-2-tolyl)-4-(4-aminocarbonylpiperazinylmethyl)-6-[a-aminocarbonyl-2,6-dichlorobenzyl]pyridine; mitogen-activated protein kinase inhibitor; antiinflammatory agent, autoimmune diseases |
| 09/09/2008 | US7423044 A cyclopenta[d]pyrimidine, or 5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine derivatives; treating metabolic disorders, type II diabetes, controlling glucose levels |
| 09/09/2008 | US7423039 (4-phenylpiperazin-1-yl)acylpiperidine derivatives, preparation thereof and application of same in therapeutics |
| 09/09/2008 | US7423033 Hydroxyalkanoylaminolactams and related structures as inhibitors of aβ protein production |
| 09/09/2008 | US7423030 1-amino-phthalazine derivatives, the preparation and the therapeutic use thereof |
| 09/09/2008 | CA2460865C Quinoline derivatives as neuropeptide y antagonists |
| 09/09/2008 | CA2287881C Vitamin d3 analogs with bis c-20 side chains |
| 09/09/2008 | CA2252163C D-proline derivatives |
| 09/09/2008 | CA2225756C Substituted cyanophenyl uracils |
| 09/09/2008 | CA2211646C Substituted phenyl compounds as endothelin antagonists |
| 09/04/2008 | WO2008106692A1 Pim kinase inhibitors and methods of their use |
| 09/04/2008 | WO2008106635A1 Pyrimidine-2,4-diamine derivatives and their use as jak2 kinase inhibitors |
| 09/04/2008 | WO2008106104A2 Environmentally sensitive fluorophores |
| 09/04/2008 | WO2008105515A1 Novel hydroxamic acid derivative |
| 09/04/2008 | WO2008105497A1 Benzimidazole compound and pharmaceutical use thereof |
| 09/04/2008 | WO2008105442A1 Sulfonamide derivative |
| 09/04/2008 | WO2008105408A1 Novel pyrrole derivative having ureide group and aminocarbonyl group as substituents |
| 09/04/2008 | WO2008105383A1 Pyrazole derivative and use thereof for medical purposes |
| 09/04/2008 | WO2008105058A1 Sulfonamides |
| 09/04/2008 | WO2008104869A1 Nicotinamide derivatives as inhibitors of h-pgds and their use for treating prostaglandin d2 mediated diseases |
| 09/04/2008 | WO2008104754A1 Novel pyrimidine derivatives 698 |
| 09/04/2008 | WO2008104589A1 Novel dosage form |
| 09/04/2008 | WO2008104278A1 Imidazo[1,2-a] pyridines and their use as pharmaceuticals |
| 09/04/2008 | WO2008104077A1 Small molecule inhibitors of protein arginine methyltransferases (prmts) |
| 09/04/2008 | WO2008086462A3 AMINO-SUBSTITUTED QUINAZOLINE DERIVATIVES AS INHIBITORS OF β-CANTENIN/TCF-4 PATHWAY AND CANCER TREATMENT AGENTS |
| 09/04/2008 | WO2008080965A3 Hiv inhibiting 5,6-substituted pyrimidines |
| 09/04/2008 | WO2008074834A3 Isoquinolinecarboxamides as inhibitors of stearoyl-coa desaturase (scd) |
| 09/04/2008 | WO2008062253A3 Stable pharmaceutical compositions of desloratadine and processes for preparation of polymorphic forms of desloratadine |
| 09/04/2008 | WO2008047229A3 Biaryl ether urea compounds |
| 09/04/2008 | US20080214828 Process for production of sulfoxide derivatives or salts thereof in the amorphous state |
| 09/04/2008 | US20080214827 For severe and chronic pain; 1-(1-Cyclooctyl-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-ylidene-cyanamide and 2-[2-Cyanoimino-3-(1-cyclooctyl-piperidin-4-yl)-2,3-dihydro-benzoimidazol-1-yl]-acetamide |
| 09/04/2008 | US20080214826 (3R,4R)-1-(2,2-difluoroethyl)-pyrrolidine-3,4-dicarboxylic acid 3-[(5-chloro-pyridin-2-yl)-amide]-4-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide}; inhibits the coagulation factor Xa; cardiovascular disorders |
| 09/04/2008 | US20080214815 Process for preparing phenoxypyridine derivatives |
| 09/04/2008 | US20080214645 Administering 2-(1H-1-Indol-3-ylsulfanyl)benzyl]dimethyl amine; general anxiety disorder, social anxiety disorder, post traumatic stress disorder, obsessive compulsive disorder, panic disorder, panic attacks, specific phobias, social phobia and agoraphobia |
| 09/04/2008 | US20080214644 [2-(4-Fluoro-]. H-indol-3-ylsulfanyl)benzyl]dimethyl amine; depression, anxiety disorders including general anxiety disorder, social anxiety disorder, post traumatic stress disorder, obsessive compulsive disorder, panic disorder, panic attacks |
| 09/04/2008 | US20080214640 3'-{[1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydropyrazol-4-ylidene]hydrazino}-2'-hydroxybiphenyl-3-carboxylic acid or a salt; treatment of thrombocytopenia; may be coadministered with a colony stimulating factor, cytokine, chemokine, or an interleukin or cytokine receptor agonist or antagonist |
| 09/04/2008 | US20080214622 Substituted Triazole Derivatives As Oxytocin Antagonists |
| 09/04/2008 | US20080214621 Metabolic disorders; antidiabetic agents; obesity; hypotensive agents; antilipemic agents; 1-Cyclohexyl-3-naphthalen-2-ylmethyl-pyrrolidin-2-one |
| 09/04/2008 | US20080214615 N-methylaminomethyl isoindole compounds and compositions comprising and methods of using the same |
| 09/04/2008 | US20080214614 reduces intraocular pressure; primary open-angle glaucoma; effective to influence the actomyosin interactions by leading to cellular relaxation and alterations in cell-substratum adhesions |
| 09/04/2008 | US20080214613 Substituted benzimidazole compounds with dual NOS inhibitory activity and mu opioid agonist activity |
| 09/04/2008 | US20080214608 4-Amino-3,3-dimethylpiperidine; reduced toxicity, and improved pharmacology and pharmacokinetics |
| 09/04/2008 | US20080214603 5-Ht7 Receptor Antagonists |
| 09/04/2008 | US20080214575 Piperidine derivatives useful as ccr5 antagonists |
| 09/04/2008 | US20080214561 Amorphous, methylparaben cocrystal and other distinct crystalline forms; distinguished by infrared spectra, X ray powder diffraction patterns and glass transition temperatures neurodegenerative disfunction, pain, cognitive disorders |
| 09/04/2008 | US20080214558 2-[(2-(4-methylpyrazin-1-yl)-3-fluoro-5-pyridinyl)amino]-4-[(3-chloro-4-fluoro) or (3-cyanomethyl)phenylamino]pyrimidine; 2-[(4-(4-methylpyrazin-1-yl)-phenyl)amino]-4-[(3-chloro-4-fluoro) or (3-cyanomethyl)phenylamino]pyrimidine; colon, breast, stomach, urogenital, pancreatic cancers, leukemia lymphoma |
| 09/04/2008 | US20080214545 4-{3-tert-butyl-5-[({[4-(pyridin-4-yloxy)phenyl]amino}carbonyl)amino]-1H-pyrazol-1-yl}-N-(2-pyrrolidin-1-ylethyl)benzamide; antiproliferatives; angiogenesis inhibitors |
| 09/04/2008 | US20080214544 N-(4-(6-(1-methyl-6-oxo-2-(phenylamino)-1,6-dihydropyrimidin-5-yl)pyridin-3-yloxy)pyridin-2-yl)pyrrolidine-1-carboxamide; anticarcinogenics, antiproliferatives, angiogenesis inhibitors; hepatocyte growth factor mediated diseases |
| 09/04/2008 | US20080214543 Antiandrogen; prostate cancer; excellent oral pharmacokinetics |
| 09/04/2008 | US20080214542 1-(5-methoxyisoindolin-2-yl)-6-[4-(3-trifluoromethylphenyl)piperazin-1-yl]hexan-1-one; amidation of an isoindole with a 4-phenylpyrimidinylalkanoic acid or amination of a N-haloalkylcarbonyl isoindole with a 4-phenylpyrimidine; antidepressant, neuroleptic agent; drug abuse, impotency, Parkinson's Disease |
| 09/04/2008 | US20080214539 Benzisoxazole Piperidine Compounds and Methods of Use Thereof |
| 09/04/2008 | US20080214536 4-((4aR,10bR)-8,9-Dimethoxy-1,2,3,4,4a,10b-hexahydro-phenanthridin-6-yl)-N-(2-methoxyethyl)-N-methyl-benzamide; phosphodiesterase 4 inhibitors; respiratory system disorders |
| 09/04/2008 | US20080214533 Anticoagulants, thrombolytic agents; amidating a p-(hydroxy-protected alkylamino)aniline with a (hetero)arylaminocarbonyl-(hetero)aryl carboxylic acid; deblocking, reacting with cyanogen bromide and cyclizing |
| 09/04/2008 | US20080214524 e.g. N-[2-(3-fluorophenyl)ethyl]-N'-isoquinolin-5-ylurea; opioid receptor inhibitor; analgesic, antiinflammatory agent; inflammatory thermal hyperalgesia, urinary incontinence and bladder overactivity |
| 09/04/2008 | US20080214495 Heterocyclic Sulfonamide Derivatives as Inhibitors of Factor Xa |
| 09/04/2008 | US20080214394 N-(4-Pyridyl)Methylsulfonamides For Combating Arthropodal Pests |
| 09/04/2008 | US20080213283 Using interleukin-1 inhibitor as therapeutic agent in treatment of spinal cord injury and nervous system disorders; for example, Pralnacasan (VX-740), thalidomide, pentoxifylline, a lazaroid, cyclosporin A |
| 09/04/2008 | US20080213181 Preparation of Paramagnetic Nanoparticles Conjugated to Leukotriene B4 (LTB4) Receptor Antagonists, and Their Use as MRI Contrast Agents for the Detection of Infection and Inflammation |
| 09/04/2008 | US20080210907 Gelling agent, carbon nanotubes aqueous dispersing agent; simple synthesis from low cost, readily available raw materials; rapid elastic modulus recovery; environmentally friendly |
| 09/04/2008 | DE102007010801A1 Use of new or known 2,4-diaminopyrimidine derivatives as fungicides |
| 09/04/2008 | CA2679659A1 Pim kinase inhibitors and methods of their use |
| 09/04/2008 | CA2679525A1 Novel dosage form |
| 09/04/2008 | CA2679489A1 Pyrimidine-2,4-diamine derivatives and their use as jak2 kinase inhibitors |
| 09/04/2008 | CA2679263A1 Sulfonamide compound |
| 09/04/2008 | CA2678735A1 Novel pyrrole derivative having ureido group and aminocarbonyl group as substituents |
| 09/03/2008 | EP1964925A1 Process for production of optically active 4-hydroxy-1,2,3,4 -tetrahydroquinolines |
| 09/03/2008 | EP1964839A2 Quinazoline derivatives as kinase inhibitors |
| 09/03/2008 | EP1963307A1 3- (4- { [4-(4-{ [3-(3, 3-dimethyl-1-piperidinyl) propyl[0xy] phenyl) -1-piperidinyl carbonyl }-1-naphthalenyl) propanoic or propenoic acid as h1 and h3 receptor antagonists for the treatment of inflammatory and/or allergic disorders |
| 09/03/2008 | EP1963306A2 Esomeprazole arginine |
| 09/03/2008 | EP1963305A1 An improved process for preparing of, impurities free, substituted 2-benzimidazolesulfoxide compound |
| 09/03/2008 | EP1963304A1 Isoquinoline derivatives |
| 09/03/2008 | EP1963303A2 Chemical compounds |
| 09/03/2008 | EP1963302A2 Polymorphs of a c-met/hgfr inhibitor |
| 09/03/2008 | EP1963286A1 Pyrazinecarboxamide derivatives and plant disease controlling agents containing the same |
| 09/03/2008 | EP1963285A1 Bradykinin 1 receptor antagonists |
| 09/03/2008 | EP1963284A1 Novel quinazoline-2,4-diamine derivatives and their use as modulators of small-conductance calcium-activated potassium channels |
| 09/03/2008 | EP1963283A2 Trisubstituted quinazolinone derivatives as vanilloid antagonists |
| 09/03/2008 | EP1963282A1 Sulfoximine-substituted pyrimidines , their preparation and use as drugs |
| 09/03/2008 | EP1963281A2 Heterocyclic derivatives as modulators of ion channels |
| 09/03/2008 | EP1963276A1 N-linked aryl heteroaryl inhibitors of lta4h for treating inflammation |
| 09/03/2008 | EP1963275A2 P2x7 receptor antagonists and uses thereof |
| 09/03/2008 | EP1963273A2 Substituted isoquinoline-1,3(2h,4h)-diones, 1-thioxo-1,4-dihydro-2h-isoquinoline-3-ones and 1,4-dihydro-3(2h)-isoquinolones and use thereof as kinase inhibitors |
| 09/03/2008 | EP1963272A1 Hydroxyquinoline derivatives |
| 09/03/2008 | EP1963269A2 Process for amination of acrylic macromonomers and products therefrom |
| 09/03/2008 | EP1962852A2 Compounds, compositions and methods |
| 09/03/2008 | EP1962849A1 Quinoline derivatives useful in the treatment of mglur5 receptor-mediated disorders |
| 09/03/2008 | EP1879581B1 4-PHENYL-5-0X0-l,4,5,6,7,8-HEXAHYDR0QËIN0LINE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF INFERTILITY |
| 09/03/2008 | EP1761497B1 Azadecalin glucocorticoid receptor modulators |
| 09/03/2008 | EP1730112B1 3-((hetero)arylsulfonyl)-8'[ (aminoalkyl)oxy]quinolines as 5-ht6 receptor antagonists for the treatment of cns disorders |
| 09/03/2008 | EP1718613B1 Pyridine derivatives and their use as cb2 receptor modulators |
| 09/03/2008 | EP1465626B1 Pharmaceutical compositions (kit) comprising dihydropyridinone compounds and an immunoregulatory (or an antiinflammatory) agent and their uses |
| 09/03/2008 | EP1375495B1 Method for producing a 2-azetidinone derivative |
| 09/03/2008 | EP1343781B1 Inhibitors of c-jun n-terminal kinases (jnk) and other protein kinases |
| 09/03/2008 | EP1311480B1 New amidino derivatives and their use as thrombin inhibitors |
| 09/03/2008 | EP1262477B1 Anti-acid-fast bacterial agents containing pyridonecarboxylic acids as the active ingredient |
| 09/03/2008 | EP1042293B9 Substituted pyridine and pyridazine compounds and their pharmaceutical use |
| 09/03/2008 | CN101258150A Heteroaryl benzamide derivatives for use as glk activators in the treatment of diabetes |