Patents
Patents for C07D 401 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom (107,979)
07/2008
07/03/2008CA2673299A1 Pyridazinones compounds for the treatment of proliferative diseases
07/03/2008CA2673233A1 Process for preparing ccr-5 receptor antagonists utilizing 4-substituted 1-cyclopropane-sulfonyl-piperidinyl compounds
07/03/2008CA2673231A1 Heterocyclic compounds with cxcr3 antagonist activity
07/03/2008CA2673041A1 4-{4-[({3-tert-butyl-1-[3-(hydroxymethyl) phenyl]-1h-pyrazol-5-yl } carbamoyl)-amino] -3-fluorophenoxy} -n-methylpyridine-2-carboxamide as well as prodrugs and salts thereof for the treatment of cancer
07/03/2008CA2673003A1 Quinazolines for pdk1 inhibition
07/03/2008CA2672951A1 Hydroxy methyl phenyl pyrazolyl urea compound useful in the treatment of cancer
07/03/2008CA2672835A1 Processes for the preparation of (3r, 4r) -n- (4-chlorophenyl) -1- (2, 2-difluoroethyl) -n'- [2-fluoro-4- (2-oxo-1 (2h) -pyridinyl) phenyl] -3 , 4-pyrrolidinedicarboxamide
07/03/2008CA2672639A1 Indol-4-yl-pyrimidinyl-2-yl-amine derivatives and use thereof as cyclin dependant kinase inhibitors
07/03/2008CA2672518A1 Organic compounds and their uses
07/03/2008CA2672440A1 Substituted heterocycles and methods of use
07/03/2008CA2672438A1 Substituted heterocycles and methods of use
07/03/2008CA2671770A1 Novel intermediate and process useful in the preparation of {2-[1-(3,5-bistrifluoromethyl-benzyl)-5-pyridin-4-yl-1h-[1,2,3]triazol-4-yl]-pyridi n-3-yl}-(2-chlorophenyl)-methanone
07/03/2008CA2671766A1 Modulators of c3a receptor and methods of use thereof
07/02/2008EP1939625A2 Methods for ligand discovery
07/02/2008EP1939195A1 New indole derivatives and their use as medicine
07/02/2008EP1939194A1 Bicyclic aromatic substituted pyridone derivative
07/02/2008EP1939189A1 Derivative having ppar agonistic activity
07/02/2008EP1939185A1 New types of hetaryl-phenylendiamin-pyrimidines as protein kinase inhibitors for the treatment of cancer
07/02/2008EP1939181A1 Heteroaryl-substituted carboxamides and use thereof for the stimulation of the expression of NO synthase
07/02/2008EP1939180A1 Heteroarylacrylamides and their use as pharmaceuticals for the stimulation of the expression of endothelial NO synthase
07/02/2008EP1939179A1 Stable S-nitrosothiols, method of synthesis and use
07/02/2008EP1938686A1 Substituted 1-(3-pyridinyl)pyrazol-4-yl-acetic acids, process for their preparation and their use as herbicide and plant growth regulator.
07/02/2008EP1937686A1 New anti-malaria derivatives of 4-aminoquinoline
07/02/2008EP1937682A1 Met kinase inhibitors
07/02/2008EP1937670A1 Benzimidazolones which have activity at m1 receptor
07/02/2008EP1937667A2 Benzimidazoles useful as inhibitors of protein kinases
07/02/2008EP1937666A1 Substituted heterocyclic compounds with cxcr3 antagonist activity
07/02/2008EP1937665A1 4- (4-BROMO-2-FLUOROANILINO) -6-METHOXY-7- (l-METHYLPIPERIDIN-4 -YLMETHOXY) QUINAZOLINE MONOHYDRATE
07/02/2008EP1937664A1 Hydrazide compound and pesticidal use of the same
07/02/2008EP1937652A1 Pyrimidine amide compounds as pgds inhibitors
07/02/2008EP1937650A1 Heterocyclic compounds
07/02/2008EP1937649A1 Imidazole derivatives for the treatment of anxiety and related diseases
07/02/2008EP1937259A1 Hexahydro-cycloheptapyrazole cannabinoid modulators
07/02/2008EP1937252A2 Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration
07/02/2008EP1830841B1 Cycloalkyl lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
07/02/2008EP1727805B1 1-phenyl and 1-pyridylpyrazole derivatives and their use as pesticides
07/02/2008EP1646626B1 Pyrrole-2, 5-dione derivatives as liver x receptor modulators
07/02/2008EP1646625B1 Pyrrole-2, 5-dithione derivatives as liver x receptor modulators
07/02/2008EP1633702B1 Protease inhibitors
07/02/2008EP1569911B1 Indazole derivatives as crf antagonists
07/02/2008EP1501808B1 Tachykinin receptor antagonists
07/02/2008EP1496838A4 Substituted amides
07/02/2008EP1471916B1 Treatment of rheumatoid arthritis using imatinib
07/02/2008CN101213194A Indazoles useful in treating cardiovascular diseases
07/02/2008CN101213192A Pyrimidine-substituted benzimidazole derivatives as protein kinase inhibitors
07/02/2008CN101213190A Compounds and compositions as TPO mimetics
07/02/2008CN101213189A 4-(pyridin-3-yl)-2-(pyridin-2-yl)-1,2-dihydro-3h-pyrazol-3-one derivatives as specific hif-prolyl-4-hydroxylase inhibitors for treating cardiovascular and haematological diseases
07/02/2008CN101213188A Amino-5-(5-membered)hetero-arylimidazolone compounds and the use thereof for beta-secretase modulation
07/02/2008CN101213187A Isoquinoline derivatives as inhibitors of RHO-kinase
07/02/2008CN101213186A Phenylpyridine derivatives, their manufacture and use as pharmaceutical agents
07/02/2008CN101213185A Pyridyl and phenyl substituted piperazine-piperidines with CXCR3 antagonist activity
07/02/2008CN101213184A Heteroaryl-substituted amides comprising an unsaturated or cyclic linker group, and their use as pharmaceuticals
07/02/2008CN101213183A Amino-5-(6-membered)heteroarylimidazolone compounds and the use thereof for beta-secretase modulation
07/02/2008CN101213174A Oxindole compounds and their uses as therapeutic agents
07/02/2008CN101212973A 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives as medicaments for the treatment of infertility
07/02/2008CN101212972A 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives as medicaments for the treatment of infertility
07/02/2008CN101212971A 4-phenyl-5-0x0-l,4,5,6,7,8-hexahydr0quin0line derivatives as medicaments for the treatment of infertility
07/02/2008CN101209995A 5-amidopyrazole derivatives, preparation method and use thereof
07/02/2008CN101209987A Thermosetting resin composition containing maleimide and/or vinyl compound
07/02/2008CN100398535C Piperidine derivatives and their use as modulators of chemokine receptor activity especially CCR5
07/02/2008CN100398534C New method of synthesizing thalidomide and its derivative
07/02/2008CN100398521C 2,5-dioxoimidazolidin-4-yl acetamides and analogues as inhibitors of metalloproteinase MMP12
07/02/2008CN100398103C Treatment of affective disorders by the combined action of a nicotinic receptor agonist and a monoaminergic substance
07/01/2008US7393959 Di-aryl substituted pyrrole modulators of metabotropic glutamate receptor-5
07/01/2008US7393958 Triamide-substituted heterobicyclic compounds
07/01/2008US7393957 Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
07/01/2008US7393873 Arylsulfonamide derivatives
07/01/2008US7393866 Anticholesterol agents; antilipemic agents; cardiovascular disorders; antiischemic agents; anticancer agents
07/01/2008US7393861 Derivatives of 4-aminopiperidine and their use as a medicament
07/01/2008US7393852 analgesics; antiinflammatory agents; antiarthritic agents;Alzheimer's disease; cirrhosis; antiallergens; antihistamines ; anticancer agents; vision defects
07/01/2008US7393850 Inhibiting the proteolytic activity of cathepsin S; 1-[4-(5-Chloro-1H-indol-3-yl)-piperazine-1-yl]-3-[5-methanesulfonyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-propan-2-ol; antiarthritic agent; autoimmune disease: lupus, rheumatoid arthritis, and asthma
07/01/2008US7393849 N-[4-Amidinobenzoyl]-N-[3-phenoxybenzyl]-3-(4-biphenyl)-alanyl-glycyl-amide; anticarcinogenic, antidiabetic, anticholesterol agent, cardiovascular disorders, osteoporosis
07/01/2008US7393846 phosphodiesterase type 4 inhibitors; N-(3,5-dichloropyrid-4-yl)-4-difluoromethoxy-8-methanesulfonamido-dibenzo[b,d]furan-1-carboxamide; antiinflammatory agent, antiallergen; asthma or chronic obstructive pulmonary disease
07/01/2008US7393845 2-{2-[4-(2,3-Dihydrobenzo[1,4]dioxin-5-yl)piperazin-1-yl]ethylsulfanyl}-6-methylnicotinonitrile; serotonin and dopamine receptor antagonist, serotonin reuptake inhibitor; anxiolytic agent, antidepressant; panic and obsessive compulsive disorder, social phobia, eating disorders, psychosis
07/01/2008US7393844 Tetrahydropyranyl cyclopentyl heterocyclic amide modulators of chemokine receptor activity
07/01/2008US7393842 Pyrazole analogs acting on cannabinoid receptors
06/2008
06/26/2008WO2008076883A2 Triazine derivatives and their therapeutical applications
06/26/2008WO2008076860A1 4-imidazolyl-1,2,3,4-tetrahydroquinoline derivatives and their use as aldosterone/11-beta-hydroxylase inhibitors
06/26/2008WO2008076685A2 Process for the preparation of piperazinyl and diazepanyl benzamide derivatives
06/26/2008WO2008076336A2 Imidazoles as aldosterone synthase inhibitors
06/26/2008WO2008076048A1 Indazolyl ester and amide derivatives for the treatment of glucocorticoid receptor mediated disorders
06/26/2008WO2008076046A1 Novel 2-amino-5, 5-diaryl-imidazol-4-ones
06/26/2008WO2008076045A1 Novel 2-amino- 5-aryl-imidazol-4 -ones
06/26/2008WO2008075462A1 Helicobacter pylori eradicating agent having inhibitory activity on gastric acid secretion
06/26/2008WO2008075118A1 Novel cb1 antagonists and their preparation
06/26/2008WO2008075077A1 Piperidine derivatives for the treatment of obesity
06/26/2008WO2008075070A1 Sulfonamide derivatives for therapeutic use as fatty acid synthase inhibitors
06/26/2008WO2008075064A1 Piperidine derivatives for the treatment of obesity
06/26/2008WO2008075040A2 Radioactive pet agents for imaging ccr5 in vivo
06/26/2008WO2008075019A1 Modulators of cb1 receptors
06/26/2008WO2008075012A1 Cb1 receptor modulators
06/26/2008WO2008074997A1 Pyridine benzamides and pyrazine benzamides used as pkd inhibitors
06/26/2008WO2008074982A1 Pyrazole derivatives as modulators of cannabinoid receptor
06/26/2008WO2008074834A2 Isoquinolinecarboxamides as inhibitors of stearoyl-coa desaturase (scd)
06/26/2008WO2008074833A2 Compounds
06/26/2008WO2008074832A2 Isoquinolinecarboxamides as inhibitors of stearoyl-coa desaturase ( scd)
06/26/2008WO2008074824A2 Isoquinolinecarboxamides as inhibitors of stearoyl-coa desaturase (scd)
06/26/2008WO2008074816A1 Compounds with a combination of cannabinoid-cb1 antagonism and acetylcholinesterase inhibition
06/26/2008WO2008074814A1 Pyrazole derivatives as non-steroidal glucocorticoid receptor ligands
06/26/2008WO2008074703A1 Heteroaryl pyrrolidinyl and piperidinyl ketone derivatives