Patents for C07B 53 - Asymmetric syntheses (6,231)
06/2008
06/03/2008CA2350473C Method for producing optically active .alpha.-aminonitriles and .alpha.-amino acids
05/2008
05/29/2008WO2008061663A1 Imidazo[1,5-b]pyridazinamido ligands and their complexes
05/29/2008US20080125601 Key steps in the synthesis are early introduction of the correct absolute stereochemistry at C-3 (R) and subsequent regioselective chain lengthening; Unlike the linear synthesis processes in the prior art, the use of the novel statin side chain building blocks allows a convergent synthesis
05/29/2008DE102006055716A1 Imidazo(1,5-b)pyridazin-amido-Liganden und deren Komplexverbindungen Imidazo (1,5-b) pyridazine-amido ligands and their complexes
05/28/2008EP1925611A1 Optically active diamine derivative and process for producing the same
05/28/2008EP1924588A1 Chiral phosphoramidites
05/28/2008EP1506148B1 Process for the preparation of enantiomerically enriched compounds
05/27/2008US7378034 Acidity and dissociation; stability, for doping polymers, as electrolytes in batteries
05/21/2008CN101182308A Imidazole chiral ionic liquids containing double function groups as well as preparation method and uses thereof
05/20/2008US7375244 efficiently catalyzes an enantio selective asymmetric nucleophilic addition reaction of an alpha -iminophosphonic acid ester
05/20/2008US7375136 Such as 1-(4-methanesulphonamidepheoxy)3-(N-methyl-3,4-dichlorophenylethylamino)-2-propanol; synthesis; effective against brain and/or spinal cord tissue acidification disorders
05/20/2008CA2155802C Enantiomerically pure pyridylcycloalkylethylamines and the salts thereof and processes for preparing them
05/15/2008WO2008055963A1 Novel method for producing organic phosphorus compounds, phosphorus compounds produced using said method, the metal complexes of said compounds, and use of same
05/15/2008US20080112866 Functionalized ionic liquids, and methods of use thereof
05/13/2008US7371865 Reacting an organophosphouus compound with metallized alkane; forming atorvastatin, lorastatin, pitavastatin, fluvastatin
05/08/2008WO2008053652A1 Process for production of hydroxyadamantaneamine
05/07/2008EP1918271A1 Process for producing optically active ester
05/07/2008EP1509216B1 Active ingredient salts and esters of 1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol and 3-(3-dimethylamino-1-ethyl-1-hydroxy-2-methyl-propyl)-phenol
05/02/2008WO2008050829A1 Method of producing s-(-)-6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid and product obtained by the method
05/02/2008WO2008050661A1 Method for producing asymmetric copper complex crystal
05/01/2008US20080103316 Reduction of 4-aryl-4-ketobutanoic acid derivatives utilizing ruthenium containing catalysts
04/2008
04/30/2008CN100384791C Catalytic hydrogeneration of carbon-heteroatom double bonds
04/29/2008US7365210 Method for the production of chiral imidazolidin-2-ones
04/24/2008WO2008046950A1 P,s-type bidentate chiral ligands and use thereof in the pauson-khand reaction
04/23/2008EP1912679A2 Amine-containing lipids and uses thereof
04/23/2008CN101166708A Optically active 3-methylcyclopentadecanone and method for producing intermediate thereof
04/22/2008US7361786 Polymer enlarged ligands or complexes advantageous in catalytic processes carried out in a membrane reactor; high enantiomeric purity
04/16/2008EP1911516A1 Homogeneous asymmetric hydrogenation catalyst
04/15/2008US7358382 Two alcohol groups of 2,2-dimethyl-pentane-nitrile compound are protected with benzyl, 4-methoxybenzyl, 3,4-dimethoxybenzyl, triethylsilyl, trimethylsilyl, triisopropyl, tetrahydropyran, methyloxymethyl, allyl, trityl
04/15/2008US7358073 Process for the preparation of aminoalcohol derivatives and their further conversion to (1R, 4S)-4(2-amino-6-chloro-5-formamido-4- pyrimidinyl)-amino-2-cyclopentenyl-1-methanol
04/15/2008CA2349325C Process for converting an alcohol to the corresponding fluoride
04/15/2008CA2337452C Process for the preparation of 4,5-diamino shikimic acid derivatives
04/15/2008CA2240107C Novel diphenylarsines
04/10/2008WO2008041571A1 Process for producing optically active beta-hydroxy-alpha-aminocarboxylic acid ester
04/10/2008WO2008041029A1 Chiral phosphorus compound
04/09/2008EP1908747A1 Process for producing optically active 2-hydroxybutyric ester
04/09/2008CN101157686A Method for selectively preparing (S)- rebeprazole by high enantiomer
04/09/2008CN101157655A Method for synthesizing (4S,5R)- half-ester
04/08/2008CA2203183C Process for producing derivatives of 4a,5,9,10,11,12,-hexahydro-6h-benzofuro[3a,3,2-ef][2]benzazepine
04/03/2008WO2008038578A1 OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING α-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME
04/02/2008EP1905760A1 Process for production of optically active aminopentane derivative, intermediate in the process and process for production of the intermediate
04/02/2008CN100378081C Process for the manufacture of organic compounds
04/01/2008US7351849 Process for producing optically active β-amino acid derivatives
04/01/2008US7351835 Organic molecular cataylst having binaphthol skeleton and processes for producing the same and application thereof
03/2008
03/27/2008WO2008035687A1 METHOD FOR PRODUCING PHOSPHORUS-CONTAINING α-AMINO ACID AND PRODUCTION INTERMEDIATE THEREOF
03/27/2008WO2008034809A1 Diphosphines and metal complexes
03/27/2008US20080076817 Neurotrophic N-glyoxyl-prolyl ester compounds e.g. 3-phenyl-1-propyl (2S)-1-(3,3-dimethyl-1,2-dioxopentyl)-2-pyrrolidinecarboxylate; non-immunosuppressive; side effect reduction; neurodegenerative diseases
03/26/2008EP1658298B1 Phosphorus-containing imidazolines and metal complexes thereof
03/26/2008CN101148456A Organic phosphoric acid catalyst and its preparation method and application
03/20/2008WO2008032546A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE α-AMINO ACID BENZYL ESTER
03/20/2008WO2008032531A1 Process for production of optically active phosphorous compound
03/20/2008WO2008031889A2 Pnicogen-containing pseudochelating ligands
03/19/2008EP1900720A1 Process for production of substituted cyclopentanone
03/19/2008CN101146813A Method of producing 3-hydroxybutyraldehyde derivative
03/19/2008CN101146812A Optically active ammonium salt compound, production intermediate thereof and method for producing same
03/19/2008CN101143862A Ionic compound containing chiral amine-thiourea (urea) and its preparation method and application
03/13/2008WO2008029754A1 Process for production of optically active aminophosphinylbutanoic acid
03/13/2008CA2662391A1 Process for production of optically active aminophosphinylbutanoic acids
03/12/2008CN101139270A Method for application of enamine in palladium catalytic asymmetry allyl group alkylated reaction
03/06/2008US20080058543 Process for making chiral 1,4-disubstituted piperazines
03/06/2008US20080058514 ceramide-like inhibitors; novel intermediates formed during the synthesis; Glycosphingolipids
03/05/2008CN101137602A Process for preparing enantiopure E-(2S)-alkyl-5-halopent-4-enoic acids and esters
03/04/2008US7338945 (1R,4S) or (1S,4R)-1-Amino-4-(hydroxymethyl)-2-cyclopentene D- or L-hydrogen tartrate intermediates
02/2008
02/27/2008CN101130529A Method for preparing optical activity 2,3-dihydroxy teinai hemiacetal derivant
02/20/2008EP1889826A1 Method for producing hexahydrofurofuranol derivative
02/20/2008EP1177166B1 Process for preparing (1r,2s,4r) -(-)-2- (2'- n,n-dimethylamino -ethoxy) -2- phenyl -1,7,7-tri- methyl -bicyclo 2.2.1 heptane and pharmaceutically acceptable acid addition salts thereof
02/20/2008CN100369906C Method for producing 3-amidinophenylalanine derivatives
02/19/2008US7332627 Compositions comprising a solvated metal
02/19/2008US7332622 Process for preparing optically active nitro compounds and cyano compounds
02/19/2008US7332610 Chemical intermediates for production of sibutramine
02/14/2008WO2008018520A1 Method for producing optically active hydroxycarboxylic acid derivative or salt thereof
02/14/2008WO2008018195A1 Polymer having bis(diphenylphosphino)binaphthyl group
02/13/2008EP1885732A2 CHIRAL DIPHOSPHONITES AS LIGANDS IN THE RUTHENIUM-CATALYSED ENANTIOSELECTIVE REDUCTION OF KETONES ß-KETO-ESTERS AND KETIMINES
02/13/2008EP1748975B1 Method for the production of optically active 3-alkyl carboxylic acids and the intermediate products thereof
02/13/2008CN101124234A Catalyst for asymmetric synthesis, ligand used therefor and method for producing optically active compound by asymmetric synthetic reaction using the same
02/12/2008US7329766 Process for stereoselectively reducing 4-aryl-4-oxobutanoic acid derivatives
02/06/2008EP1884509A1 Optically active 3-methylcyclopentadecanone and method for producing intermediate thereof
02/06/2008CN101120010A Metallocene-based phosphorus chiral phosphines
02/06/2008CN101117304A Method for proceeding asymmetric catalytic hydrogenation reaction
02/06/2008CN100366613C Method for preparation of (s)-(+)-and(r)-(-)10,11-dihydro-10-hydrodoxy-5h-dibenz/b,f/azephine-5-carboxamide
02/06/2008CN100366596C Process for producing 2-(l-menthoxy)ethanol compound
02/05/2008US7326559 Reacting an allene derivative containing two hydroxy or two ester groups in presence of esterase or lipase enzyme catalyst with an unsaturated ester when ( both are hydroxy groups) or with water when (both are ester groups); chemical intermediates for medicinal and agricultural active agents
02/05/2008CA2289206C Efficient enantioselective addition reaction using an organozinc reagent
02/05/2008CA2216153C Dihalogenated ferrocenes and processes for the preparation thereof
01/2008
01/31/2008WO2008013009A1 Polymer-supported metal complex catalyst
01/30/2008EP1882685A1 Method for producing asymmetric tetrasubstituted carbon atom-containing compound
01/24/2008WO2008010455A1 METHOD FOR PRODUCING β-DIARYL ELECTRON-WITHDRAWING GROUP SUBSTITUTED COMPOUND
01/23/2008CN101108850A Single-side bridged chirality metalloporphyrin compound and chirality catalytic system used for unsymmetrical oxidation reaction thereof
01/23/2008CN100363372C Preparation of partially hydrogenated rac-ansa-metallocene complexes
01/16/2008EP1737820B1 Asymmetric hydrogenation process useful for the preparation of cycloalkanoindole derivatives
01/16/2008CN100361971C Double functional group L-proline derivative with adjustable catalytic activity and its prepn
01/09/2008EP1874711A2 Asymmetric hydroformylation process
01/09/2008EP1601635B1 Process for producing optically active alcohol in the presence of rhodium, a chiral ferrocenyldiphosphine and an optically active diamine
01/09/2008CN101100428A Method for catalytically synthesizing chiral L- or D-diethyl tartrate by using boric acid
01/09/2008CN101099936A Use of chiral oxazoline
01/09/2008CN100360480C Amino group-containing chiral ionic liquid and its prepn process and application
01/08/2008US7317123 Process for preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives, intermediates thereof and methods for their preparation
01/03/2008WO2008001719A1 Method for producing optically active 1-(fluoro-, trifluoromethyl- or trifluoromethoxy-substituted phenyl)alkylamine n-monoalkyl derivative
01/03/2008WO2008000815A1 Diphosphine ligands
01/03/2008CA2656557A1 Fatty acid blends and uses therefor
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