Patents for C07B 53 - Asymmetric syntheses (6,231)
04/2012
04/11/2012CN102408287A 一种手性α-氨基酸衍生物的制备方法 A method for preparing a chiral amino acid derivative of α-
04/11/2012CN101693704B 一种合成光学活性的反式威士忌内酯的方法 Synthesizing optically active trans whiskey lactone
04/11/2012CN101544566B 一种双功能催化烯醛与硝基烷烃不对称共轭加成的方法 A dual function hexenal and nitroalkanes catalyzed asymmetric conjugate addition method
04/04/2012CN102397793A 一类金鸡纳碱-方酰胺氢键催化剂、合成方法及其在不对称反应中的应用 A class of cinchona alkaloids - square amide hydrogen catalyst synthesis method and its application in asymmetric reactions
04/04/2012CN101052612B 手性氟化分子的立体选择性制备方法 Stereoselective preparation of chiral molecules fluoride
04/03/2012CA2363284C Process for synthesizing n-(mercaptoacyl)-amino acids from alpha-substitute acrylic acids
03/2012
03/28/2012CN102391215A Synthesis method of chiral gamma-dodecalactone
03/28/2012CN101638426B New preparation method for triptolide
03/28/2012CN101374792B Method for producing optically active alcohol compound
03/21/2012CN102381990A Preparation method of optically active N-benzyl phenylephrine
03/20/2012US8138353 Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inhibitors
03/15/2012WO2011146610A3 An enantioselective synthesis of chiral amines for the production of rotigotine
03/15/2012US20120065398 Method for producing 3-amidinophenylalanine derivatives
03/14/2012CN102372533A Unsymmetrical addition method of fluoroalkyl contained arone using tartaric acid derivative catalytic terminal alkyne zinc reagent
03/07/2012CN101891668B L-prolinamide derivative, preparation method and application of same
03/07/2012CN101798290B Method for synthesizing chiral cyproconazole
02/2012
02/29/2012EP2423291A1 1-menthyl (3r)-3-hydroxybutanoate, process for producing same, and composition containing same for stimulating sense
02/29/2012EP2423290A1 Process for producing 1-menthyl (3s)-3-hydroxybutanoate and composition for stimulating sense
02/29/2012CN101239941B Process for producing optically active compound
02/22/2012EP2420507A1 Diphosphine ligand and transition metal complex using the same
02/22/2012EP2420487A1 Novel method for producing optically active pyrrolidine compound
02/22/2012EP1296927B1 Preparation of (r)-2-alkyl-3-phenylpropionic acids
02/21/2012CA2488372C Pyridazine derivatives which are phosphodiasterase iv inhibitors
02/15/2012EP2418204A1 Compound having hetero ring skeleton, and process for producing optically active compound using the aforementioned compound as asymmetric catalyst
02/15/2012EP2418190A1 The method of preparation of enantiomerically enriched products of condensation from racemic acids or acids of the low enentiomeric purity
02/15/2012EP1797028B1 Stereoselective method for preparing a chiral fluorinated molecule
02/15/2012CN102351769A Chiral 2,5-pyrroline derivative, and synthetic method and biological activity thereof
02/08/2012CN102348680A Method for producing optically active diamine derivative
02/01/2012EP2412696A1 Process for production of 3-methyl-cyclopentadecenone, process for production of r/s-muscone, and process for production of optically active muscone
02/01/2012EP2412694A1 Process for producing optically active alcohol
02/01/2012CN102336782A Mirror selective addition method of imine
02/01/2012CN102336698A Method for synthesizing chiral indoline through palladium-catalyzed asymmetric hydrogenation
01/2012
01/26/2012WO2012011516A1 Method for producing optically active 1-bromo-1-[3,5-bis(trifluoromethyl)phenyl] ethane
01/25/2012CN102329262A Chiral nitrogen-containing heterocyclic compound and synthesis method thereof
01/24/2012US8101798 Manufacture of substantially pure monochloroacetic acid
01/19/2012WO2012008228A1 Method for oxidizing alcohols
01/18/2012EP2407450A1 Method for producing optically active diamine derivative
01/18/2012EP2407447A1 Method for producing optically active 2-hydroxy ester and novel intermediate compound
01/18/2012CN102321066A Method for producing aryl-aminopropanols
01/18/2012CN102321006A Di-proline amide compound containing chiral indane framework and application thereof
01/18/2012CN101824031B Chiral oxazoline and use thereof
01/18/2012CN101065344B Method for the production of menthol
01/12/2012WO2012005200A1 Method for producing optically active 1,2-bis(dialkylphosphino)benzene derivative
01/11/2012CN101735209B Method for synthesizing chiral dorzolamide hydrochloride
01/11/2012CN101039898B Titanium compound and process for producing optically active cyanohydrins
01/05/2012WO2012002203A1 Β-aminocarbonyl compound production method
01/04/2012EP2402328A1 Method for producing optically active fluorinated oxetane
01/04/2012EP1908747B1 Process for producing optically active 2-hydroxybutyric ester
01/04/2012CN102304007A Asymmetric catalytic hydrogenation reaction method of intra-annular N-alkylimine
01/04/2012CN101585834B Preparation and use of aromatic heterocyclic methylene BOZ
01/03/2012US8088921 Method for producing 3-amidinophenylalanine derivatives
01/03/2012CA2531898C Process for producing optically active .beta.-hydroxy-.alpha.-aminoc arboxylic acid derivative
12/2011
12/28/2011EP2088144B1 Method of producing s-(-)-6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid
12/28/2011CN101972668B 一种手性双膦酰二胺噁唑啉的新用途 The new use of a chiral bisphosphine carbamide oxazoline
12/21/2011CN102285984A (2R,3R,11bR)-二氢丁苯那嗪及相关化合物的制备方法 (2R, 3R, 11bR) - Preparation dihydrotetrabenazine and related compounds
12/21/2011CN101747463B 一种多孔交联聚苯乙烯树脂负载金鸡纳碱类化合物及其制备方法 A porous cross-linked polystyrene resin load cinchona alkaloids compounds and methods
12/21/2011CN101733153B 一种多孔交联聚苯乙烯磺酸树脂负载型金鸡纳碱类季铵盐及其制备方法 A porous cross-linked polystyrene sulfonic acid resin supported cinchona alkaloids quaternary ammonium salt and its preparation method
12/21/2011CN101585795B (s)型硫代咪唑啉酮类化合物催化不对称烷基化反应方法 Catalytic (s) type thio imidazolinone compound asymmetric alkylation reaction process
12/21/2011CN101117304B 一种进行不对称催化氢化反应的方法 A method of asymmetric hydrogenation reaction proceeds
12/14/2011EP2394977A1 Process for producing optically active alcohol
12/14/2011CN102282135A 一种(4s,5r)-半酯的制备方法 One kind (4s, 5r) - half ester preparation
12/14/2011CN102274754A 一种提高多相不对称催化活性和不对称选择性的方法 An asymmetric heterogeneous asymmetric catalytic activity and selectivity of the method to improve
12/13/2011US8076504 Method for production of short chain carboxylic acids and esters from biomass and product of same
12/08/2011DE102009055183B3 Preparing aryl-substituted nitroalkane derivatives comprises arylation of nitroalkene derivative with boroaryl compound in presence of palladium salt or palladium complex in water or in mixture of water and water miscible organic solvent
12/07/2011EP2392400A2 Homogeneous asymmetric hydrogenation catalyst
12/07/2011EP1813619B1 Process for producing penam compound
12/07/2011CN102267954A 一种手性噁唑啉及其合成方法 Chiral oxazoline and synthesis method
12/07/2011CN101486692B 一种光学纯的(r)-4-多卤甲基-2-杂环丁酮的制备方法 An optical pure (r) -4- methyl-2-oxetanone polyhalogenated preparation
12/07/2011CN101215256B 2-氨甲基(4,7-二氢吲哚)化合物、合成方法及用途 2-aminomethyl-(4,7-dihydro-indole) compounds, synthetic methods, and uses
12/07/2011CN101003549B 一种具有平面手性环芳烷的膦化合物、合成方法及用途 A phosphine compound having a planar chiral paracyclophane, synthetic methods and uses
12/01/2011WO2011108672A3 Homogeneous asymmetric hydrogenation catalyst
11/2011
11/30/2011CN102264753A 手性配体 Chiral ligands
11/30/2011CN102264672A 使用转移氢化制备旋光化合物的方法 The method of transfer hydrogenation using an optically active compound prepared
11/30/2011CN102260131A 对烯酮进行镜像选择性加成的方法 Mirroring for selective addition of ketene method
11/24/2011WO2011145352A1 Titanium-containing catalyst and process for preparation of optically acitive cyano compounds
11/23/2011CN102249833A Method for preparing chiral gamma-amino acid and derivatives thereof
11/23/2011CN101166708B Optically active 3-methylcyclopentadecanone and method for producing intermediate thereof
11/22/2011US8063244 Process for the synthesis of pregabalin
11/16/2011CN101735368B Sulfonated porous crosslinked polystyrene resin loaded cinchona alkaloid compound and preparation method thereof
11/16/2011CN101411996B Macromolecule supported Cinchona bases compound, production method and application
11/09/2011CN102234291A Bridged bis-Schiff-base-titanium complex, and synthesis method and application thereof
11/02/2011EP2382172A1 Process for the preparation of optically active compounds using transfer hydrogenation
11/02/2011EP2381772A1 Process and intermediates for the preparation of n-acylated-4-aryl beta-amino acid derivatives
11/02/2011CN102228842A Supported iron-based chiral complex catalyst and preparation method and application thereof
10/2011
10/26/2011EP2041150B1 Diphosphine ligands
10/26/2011EP1905760B1 Process for production of optically active aminopentane derivative, intermediate in the process and process for production of the intermediate
10/26/2011EP1889826B1 Method for producing a hexahydrofurofuranol derivative
10/20/2011WO2011129365A1 Antitumor agent
10/19/2011EP2376509A1 Chiral ligands
10/19/2011EP1731509B1 Process for producing nitrogenous 5-membered cyclic compound
10/18/2011CA2462345C Dimeric compounds and their use as anti-viral agents
10/13/2011WO2011126082A1 Method for producing acyloxypyranone compound, method for producing alkyne compound, and method for producing dihydrofuran compound
10/13/2011WO2011126045A1 Process for preparation of pyrazine derivatives
10/12/2011CN102216312A Chiral ligands
10/12/2011CN102216251A Method for producing optically active cyclopropane carboxylic acid ester compound, asymmetric copper complex, and optically active salicylideneaminoalcohol compound
10/12/2011CN101298461B Use of oxazoline phosphine ligand in unsymmetrical catalytic hydrogenation of ketene compounds for synthesizing alpha-chiral carbon-containing ketone compound
10/11/2011US8034961 Reduction of 4-aryl-4-ketobutanoic acid derivatives utilizing ruthenium containing catalysts
10/11/2011CA2453978C Synthesis of udp-glucose: n-acylsphingosine glucosyltransferase inhibitors
10/06/2011WO2011121797A1 Hybrid inorganic/organic polymer catalytic membrane materials comprising immobilized molecular catalysts and their preparation
10/05/2011EP2371820A1 Optically active cyclic alcohol compound and method for preparing the same
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