Patents for C07B 53 - Asymmetric syntheses (6,231)
01/2007
01/30/2007US7169953 For use as catalysts in asymmetric reactions, such as, hydrogenation, hydride transfer, allylic alkylation, hydrosilylation, hydroboration, hydrovinylation, hydroformylation, olefin metathesis, hydrocarboxylation
01/30/2007US7169938 Synthesis including (S)-3-Hydroxy-3-(2-thiophen-yl)-N-methylpropionamide, and (R)-3- hydroxy-3-(2-thiophen-yl)-N-methylpropionamide; intermediates to drugs such as fluoxetine
01/30/2007US7168937 Method for the enzymatic resolution of the racemates of aminomethyl-aryl-cyclohexanol derivatives
01/30/2007CA2165043C Process for the preparation of the enantiomers of 2-(2-fluoro-4-biphenyl)propionic acid
01/24/2007EP1745787A2 Non-calcemic, antiproliferative, transcriptionally active sulfur-containing analogs of 1-alpha 25-dihydroxy Vitamin D3
01/24/2007EP1745056A2 Enantioselective phosphoramidite compounds and catalysts
01/24/2007EP1590317B1 ENANTIOMER-PURE (4S,8S)- AND (4R, 8R)-4-P-NITROBENZYL-8-METHYL-3, 6, 9-TRIAZA- SP 3 /sp N, SP 6 /SP N, SP 9 /SP N-TRICARBOXYMETHYL-1, 11-UNDECANOIC ACID AND DERIVATIVES THEREOF, METHOD FOR PRODUCING THEM, AND THEIR USE FOR PRODUCING PHARMACEUTICAL AGENTS
01/23/2007US7166754 Methods and compositions for enantioselective oxidation reactions
01/23/2007CA2333192C Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-2h-pyran-2-one
01/18/2007WO2007007646A1 Homogeneous asymmetric hydrogenation catalyst
01/17/2007EP1567535B1 Bidentate c,p chiral phosphine ligands
01/17/2007EP1401575B1 Hydroxylation of beta-dicarbonyls with zirconium catalysts
01/17/2007CN1295217C New asymmetric diaryl-methylamine intermediates for the preparation of diarylmethylpiperazines derivatives
01/16/2007US7164026 Excellent as a ligand to be used in asymmetric synthesis reactions
01/11/2007WO2007004639A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE ERYTHRO-β-AMINO ALCOHOL
01/11/2007WO2007004442A1 Process for production of substituted cyclopentanone
01/11/2007US20070010695 Diphosphines, preparation and uses thereof
01/11/2007US20070010493 Phospinite-imidazolines and metal complexes thereof
01/10/2007EP1741693A1 Process for production of optically active alcohols
01/10/2007EP1534699A4 Kinetic resolution method
01/10/2007EP1203616B1 Chiral lead catalyst and method of asymmetric aldol reaction
01/09/2007US7161047 Process for preparing secondary alcohol
01/09/2007US7161002 Compounds as antiinflammartory agents, antiproliferation agents and and anticancer agents from cyclodehydration of compounds
01/09/2007CA2200490C Racemisation and asymmetric transformation processes used in the manufacture of levobupivacaine and analogues thereof
01/04/2007WO2007001015A1 Process for production of optically active aminopentane derivative, intermediate in the process and process for production of the intermediate
01/04/2007US20070004927 Chiral ligands for application in asymmetric syntheses
01/04/2007CA2612290A1 Process for preparing optically active aminopentane derivative, intermediate and process for preparing intermediate
01/03/2007EP1737820A1 Asymmetric hydrogenation process useful for the preparation of cycloalkanoindole derivatives
01/03/2007EP1419008B1 Process for performing an imino-ene reaction
01/03/2007CN1293071C Benzo [g] quinoline derivatives for treating glaucoma and myopia
01/03/2007CN1293026C Process for perparation of (R)-2-alkyl-3-phenyl-1-propanols
01/02/2007US7157498 Diamines having a CaSR modulating activity
01/02/2007CA2231093C Process for the preparation of enantiomerically pure 3-hydroxyoctanedioic acid diesters by asymmetric catalytic hydrogenation
12/2006
12/28/2006WO2006137195A1 Sulfonate catalyst and process for producing alcohol compound with the same
12/28/2006US20060293536 via non-racemic cinchona-alkaloid-type catalyst (quinidine) for addition of nucleophile
12/27/2006EP1507783B1 Hydroxy diphosphines and their use in catalysis
12/27/2006EP1385826B1 Method for preparation of (s)-(+)- and (r)-(-)-10,11-dihydro-10-hydroxy-5h-dibenz/b,f/azepine-5-carboxamide
12/26/2006US7153971 Contacting a carbohydrate with an amine to produce amino tetrahydroxy carbohydrate, protecting two hydroxy groups of tetrahydroxy carbohydrate, forming hydroxy heterocyclic-spiro moiety by reacting with activated carbonate, oxidizing OH
12/26/2006US7153960 Synthesis of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones
12/26/2006US7153809 For use as catalysts in asymmetric reactions, such as, hydrogenation, hydride transfer, allylic alkylation, hydrosilylation, hydroboration, hydrovinylation, hydroformylation, olefin metathesis, hydrocarboxylation
12/21/2006US20060287549 Catalytic asymmetric desymmetrization of prochiral and meso compounds
12/21/2006US20060287539 Chemical intermediates for production of sibutramine
12/20/2006EP1734044A1 Process for producing folic acid derivative
12/20/2006EP1515962B1 Process for the preaparation of dioxane acetic acid esters
12/20/2006EP1288198B1 Process for the production of sulfonic esters
12/14/2006WO2006132390A1 Method for producing hexahydrofurofuranol derivative
12/14/2006US20060281950 Process for producing optically active 1-alkyl-substituted 2,2,2-trifluoroethylamine
12/14/2006US20060281926 Synthesis of 2-alkylcysteine via phase transfer catalysis
12/14/2006US20060281917 Dehalogenating a 6-halo- or 6,6-dihalo-carboxylic acid-protected penicillanic acid by reacting with a metal having a lower standard oxidation-reduction potential than bismuth (e.g., Al, Fe or Mg)) in the presence of bismuth metal or a bismuth compound and a reaction promoter
12/13/2006EP1731522A1 Process for producing flavone c glycoside derivatives
12/13/2006EP1731509A1 Process for producing nitrogenous 5-membered cyclic compound
12/13/2006CN1289515C Catalyst for asymmetric (transfer) hydrogenation
12/13/2006CN1289455C 2-(2,6-dichlorophenyl)-diarylimidazoles
12/07/2006WO2006130453A1 Asymmetric aldol additions using bifunctional cinchona-alkaloid-based catalysts
12/07/2006WO2006130437A2 Asymmetric carbon-carbon-bond-forming reactions catalyzed by bifunctional cinchona alkaloids
12/07/2006US20060276643 Amine-substituted diphenyldiphosphines
12/07/2006US20060276329 Performing an asymmetric Mannich reaction, hydrophosphorylation reaction, aza Diels-Alder reaction, allylation, Strecker reaction or aminoalkylation in the presence of 1,1'-binaphthyl-2,2'-diyl hydrogenphosphate compound or the 5,5',6,6',7,7',8,8'-octahydro- derivative to prepare chiral compounds
12/07/2006DE102005025797A1 Chirale Diphosphonite als Liganden in der ruthenium-katalysierten enantioselektiven Reduktion von Ketonen, β-Ketoestern und Ketiminen Chiral diphosphonites as ligands in the ruthenium-catalyzed enantioselective reduction of ketones, β-keto esters and ketimines
12/07/2006DE102004060626B4 Monoheteroatomsubstituierte Nitroalkane und ein Verfahren zu deren Herstellung Mono heteroatom-substituted nitroalkanes and a method for their preparation
12/07/2006CA2610095A1 Chiral diphosphonites as ligands in the ruthenium-catalysed enantioselective reduction of ketones ~-ketoesters and ketimines
12/06/2006EP1727620A1 C1-symmetric bisphosphine ligands and their use in the asymmetric synthesis of pregabalin
12/05/2006CA2150382C Process for the preparation of 9-amino camptothecin
11/2006
11/30/2006WO2006126428A1 Optically active 3-methylcyclopentadecanone and method for producing intermediate thereof
11/30/2006US20060270681 Pyridazine derivatives
11/29/2006EP1187805B1 Process for preparing r-(-)-carnitine from s-(-)-chlorosuccinic acid or from a derivative thereof
11/29/2006CN1869033A Modifications of the trometamol salt of R-thioctic acid as well as a process for their production
11/23/2006WO2006123767A1 Method for producing asymmetric tetrasubstituted carbon atom-containing compound
11/23/2006WO2006123672A1 Method for producing aminoalcohol derivative having biphenyl group
11/23/2006CA2608451A1 Method for producing aminoalcohol derivative having biphenyl group
11/22/2006EP1724275A1 Process for producing aminophosphonic acid derivative
11/22/2006EP1724255A1 Process for production of cyclopentenenitrile derivatives
11/22/2006EP1724251A1 Process for production of optically active hydroxymethylated compounds
11/22/2006EP1724013A1 Asymmetric reaction catalyst and process for production of optically active compounds with the same
11/22/2006CN1285571C Preparation of 2-oxethyl-3-[4-(2-{methylsulfonyloxyphen}oxethyl)phenyl] propanoic acid
11/21/2006US7138547 Antitumoral compounds
11/16/2006US20060257978 Deracemisation of amines
11/15/2006EP1721885A1 Process for producing optically active fluorochemical
11/15/2006EP1720852A1 Process for the preparation of enantiomerically pure 1-substituted-3-aminoalcohols
11/14/2006US7135502 Colchinol derivatives as vascular damaging agents
11/14/2006CA2250062C Method for obtaining pure enantiomers of a pyridazinone derivative
11/09/2006US20060252934 For treatment of asthma, allergies, inflammation and anxiety; antihistamines; sedatives; tranquilizing agents
11/08/2006EP1719764A1 Method of asymmetrically reducing 4- 5-(imidazol-1-yl)-2-met hylbenzoyl -3,5-dimethyl-benzoic acid or ester thereof
11/07/2006US7132569 N,N-disubstituted-2,7-dialkyl-8-aryl-4-octeneamides and the intermediates: N,N-disubstituted-5-halo- or azido-2-alkyl-4-pentenamides and 2-alkyl-5-(4-aryl-2-halo- or azido-3-alkylbutylbutyrolactones that may be used to prepare them
11/02/2006US20060247458 Process for the production of optically active compounds having substituents at the 2-position
11/02/2006EP1717221A1 Processes for production of alpha-aminooxyketones and alpha-hydroxyketones
11/02/2006EP1716091A1 Method for producing optically active alcohols or carboxylic acids
11/02/2006EP1716090A1 Hydrogenation method for producing optically active alcohols or carboxylic acids
11/02/2006EP1716088A1 Catalytic asymmetric synthesis of optically active alpha-halo-car bonyl compounds
11/02/2006EP1578723A4 Process for the preparation of oxazolidinones and method of use thereof
11/02/2006EP1180035B1 NON-CALCEMIC, ANTIPROLIFERATIVE, TRANSCRIPTIONALLY ACTIVE SULFUR-CONTAINING ANALOGS OF 1-alpha, 25-DIHYDROXY VITAMIN D3
10/2006
10/31/2006US7129378 Method of preparing amine stereoisomers
10/31/2006US7129241 Pyridazine derivatives
10/26/2006US20060241315 Substitution of the 3, 5 and 4 positions of the phenyl radicals in the two phosphino groups leads to ligands whose metal complexes display higher catalytic activity and enantioselectivity in the hydrogenation of prochiral, ethylenically unsaturated compounds; producing pure enantiomers
10/26/2006US20060241307 Ligands for asymmetric reactions
10/25/2006EP1187798B8 Production of optically active alpha-hydroxyacetals
10/25/2006EP1151987B1 Optically active fluorinated binaphthol derivative
10/25/2006CN1852887A Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same
10/25/2006CN1281320C Complex catalyst, process for producing the complex catalyst and process for producing alcohol derivative with the complex catalyst
10/24/2006US7125725 Biaryl-type compounds, CD color fixing agent and method for determination of absolute configuration
10/24/2006CA2152089C Asymmetric process for preparing florfenicol, thiamphenicol, chloramphenicol, and oxazoline intermediates
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