Patents
Patents for A61P 21 - Drugs for disorders of the muscular or neuromuscular system (23,287)
10/1998
10/01/1998WO1998042675A1 Substituted isoquinolines as ultra short acting neuromuscular blockers
10/01/1998WO1998042674A1 Substituted isoquinolines as ultra short acting neuromuscular blockers
10/01/1998CA2284550A1 87 human secreted proteins
10/01/1998CA2283631A1 Secreted proteins and polynucleotides encoding them
09/1998
09/30/1998EP0866860A2 Novel tyrosine kinase receptors and ligands
09/30/1998EP0866720A1 Methods of increasing lean tissue mass using ob protein compositions
09/30/1998EP0866704A1 Use of 1-(2-naphth-2-ylethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine for preparing drugs for treating amyotrophic lateral sclerosis
09/30/1998EP0526544B1 Therapeutic uses of actin-binding compounds
09/29/1998US5814478 Isolated nucleotide sequence encoding a polypeptide for treating muscular disorders or nervous system disorders
09/24/1998WO1998041508A1 Substituted isoquinoline derivatives and their use as anticonvulsants
09/24/1998WO1998041507A1 Anti-convulsant isoquinolyl-benzamide derivatives
09/24/1998WO1998041506A1 Novel quinoline- and naphthalenecarboxamides, pharmaceutical compositions and methods of inhibiting calpain
09/24/1998WO1998041092A1 Novel indolecarboxamides, pharmaceutical compositions and methodsof inhibiting calpain
09/24/1998CA2284218A1 Substituted isoquinoline derivatives and their use as anticonvulsants
09/24/1998CA2284035A1 Novel quinoline- and naphthalenecarboxamides, pharmaceutical compositions and methods of inhibiting calpain
09/24/1998CA2283682A1 Anti-convulsant isoquinolyl-benzamide derivatives
09/22/1998US5811549 Process of preparing imidazole compounds
09/17/1998WO1998040486A2 Secreted proteins and polynucleotides encoding them
09/17/1998WO1998040404A2 Secreted proteins and polynucleotides encoding them
09/17/1998WO1998040070A1 Compositions containing capsaicin or capsaicin analogues and a local anesthetic
09/17/1998WO1998030683A3 Nuclear transfer with differentiated fetal and adult donor cells
09/17/1998CA2283227A1 Medicinal preparation containing a lipophilic inert gas
09/17/1998CA2283195A1 Secreted proteins and polynucleotides encoding them
09/17/1998CA2283193A1 Secreted proteins and polynucleotides encoding them
09/16/1998EP0863880A1 Novel 1-ar(alk)yl-imidazolin-2-ones containing a disubstituted amine radical in the 4th position, having an anti-convulsive effect, and process for their production
09/16/1998EP0707586B1 Positive inotropic and lusitropic pyrroloquinolinone derivatives
09/15/1998US5807868 Analgesics; psychological disordes; parkinson*s diesase;cognition activators; drug dependence; dyskinesia
09/15/1998US5807851 2,3-Benzodiazepine Derivatives as non-competitive AMPA
09/11/1998WO1998039444A1 Protein kinase c inhibitor-like protein (ipkc-2)
09/11/1998CA2282827A1 Method of alleviating neuropathic pain
09/11/1998CA2282709A1 Protein kinase c inhibitor-like protein (ipkc-2)
09/08/1998US5804586 Therapeutic agents
09/03/1998WO1998024764A3 Substituted benzamide derivatives and pharmaceutical compositions containing them
08/1998
08/27/1998WO1998024782A3 Substituted pyrimidine compounds and their use
08/26/1998CN1191111A Process for preparing pharmaceutical composition containing N-acyl-2,3-benzodiazepine derivatives as active ingredient
08/25/1998CA2122479C Risedronate delayed-release compositions
08/20/1998WO1998013492A3 Isolation and use of motoneuronotrophic factors
08/19/1998EP0858337A2 A pharmaceutical composition for the treatment of autoimmune diseases
08/19/1998CN1190896A Stabilized pharmaceutical formulation comprising a growth hormone and a peptide comprising at least, one basic amino acid residue and at least one acid amino acid residue
08/19/1998CN1190591A Plaster for replenishing vital essence
08/18/1998US5795908 Fkbp immunophilins for enzyme inhibitors
08/18/1998US5795903 Anticonvulsants, antianxiety, schizophrenia, sleep disorders, brain disorders and alzheimer's or parkinson's disease
08/18/1998US5795886 Anticonvulsants
08/18/1998US5795872 DNA construct for immunization
08/18/1998CA2087104C Neuromuscular blocking agents
08/13/1998WO1998034910A1 Glycerolipidic compounds used for the transfer of an active substance into a target cell
08/13/1998WO1998034907A1 Compounds consisting in particular of effectors of the central nervous system receptors sensitive to excitatory amino acids, preparation and biological applications
08/13/1998CA2251999A1 Glycerolipidic compounds used for the transfer of an active substance into a target cell
08/11/1998US5792874 Process for the manufacture of 8-chloro-6-(2-flourophenyl)-1-methyl-4H-imidazo 1,5A! 1,4!benzodiazepine (midazolam)
08/05/1998EP0649407B1 Dimeric piperidine, tetrahydropyridine and piperazine derivatives
08/05/1998CN1189834A Condesned thiazole derivatives, having 5-HT receptor affinity
08/04/1998CA2119647C Heteroaryl amines as novel acetylcholinesterase inhibitors
07/1998
07/30/1998WO1998032766A1 SUBSTITUTED AMINO BICYCLIC-β-LACTAM PENAM AND CEPHAM DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS
07/30/1998WO1998024780A3 Substituted pyrimidinone and pyridinone compounds and their use
07/30/1998CA2278779A1 Substituted amino bicyclic-.beta.-lactam penam and cepham derivatives as cysteine protease inhibitors
07/29/1998EP0854724A1 Method of treating the navicular disease in horses
07/28/1998US5786355 4,6-diarylpyrimidine derivatives and salts thereof
07/23/1998WO1998031395A1 Adenoviral-vector-mediated gene transfer into medullary motor neurons
07/23/1998WO1998031362A1 Use of pramipexole in the treatment of restless legs syndrome
07/23/1998WO1998020906A3 Treatment of diabetes with transcription factor gene
07/23/1998DE19701619A1 Verwendung von Pramipexol zur Behandlung des restless legs syndroms Use of pramipexole in the treatment of restless legs syndrome
07/23/1998CA2277869A1 Adenoviral-vector-mediated gene transfer into medullary motor neurons
07/22/1998CN1188482A Colchicine derivatives, use thereof and formulations containing them
07/16/1998WO1998030683A2 Nuclear transfer with differentiated fetal and adult donor cells
07/15/1998EP0852495A1 Pharmaceutical compositions containing hydroximic acid derivatives
07/09/1998WO1998029447A1 Novel human apoptosis regulator
07/09/1998WO1998029430A1 G-rich oligo aptamers and methods of modulating an immune response
07/09/1998CA2278340A1 Novel human apoptosis regulator
07/09/1998CA2278031A1 G-rich oligo aptamers and methods of modulating an immune response
07/08/1998EP0851935A2 Dna construct comprising a muscle specific regulatory element for immunization or gene therapy
07/08/1998EP0851875A2 Dna sequences and secreted proteins encoded thereby
07/08/1998EP0851756A1 5-ht 3? receptor antagonists for dyskinesia
07/08/1998CN1187188A Small molecule inhibitors of rotamase enzyme activity
07/07/1998US5776734 DNA encoding the β subunit of a mammalian maxi-K potassium channel
07/02/1998WO1998028301A1 Pyrrolo[3,4-d]pyrimidinone derivatives and their use as medicaments
07/02/1998CA2275312A1 Pyrrolo[3,4-d]pyrimidinone derivatives and their use as medicaments
07/01/1998CN1038931C Preparation of medicinal compositions useful as anta-gonists of excitatory amino acid neuro-transmitters and/or as blockers of calcium channels
06/1998
06/30/1998US5773436 Use of serotonin antagonists for treating fibromyalgia
06/24/1998CN1038840C Para-dinitrogen naphthalene derivative, its preparation method and medical use
06/23/1998US5770196 Modified antibody variable domains and therapeutic uses thereof
06/23/1998CA2119636C Low ph aqueous cosmetic gel containing non-ionic polyacrylamide derivatives
06/16/1998US5766886 Modified antibody variable domains
06/11/1998WO1998024922A1 Insulin-like growth factor i (igf-i) expression system and methods of use
06/11/1998WO1998024782A2 Substituted pyrimidine compounds and their use
06/11/1998WO1998024780A2 Substituted pyrimidinone and pyridinone compounds and their use
06/11/1998WO1998024764A2 Substituted benzamide derivatives and pharmaceutical compositions containing them
06/11/1998CA2273364A1 Substituted benzamide derivatives and pharmaceutical compositions containing them
06/09/1998US5763433 Pharmaceutical compositions containing 3-beta-hydroxylated 6,7-substituted steroid derivatives, and use thereof
06/09/1998US5762929 Anti-motoneuron-disease agent
06/04/1998WO1998023581A1 Benzamidoaldehydes and their use as cysteine protease inhibitors
06/04/1998WO1998023273A1 4-aryl-3-hydroxyquinolin-2-one derivatives as ion channel modulators
06/04/1998CA2272388A1 Benzamidoaldehydes and their use as cysteine protease inhibitors
06/04/1998CA2266605A1 4-aryl-3-hydroxyquinolin-2-one derivatives as ion channel modulators
05/1998
05/28/1998WO1998022500A2 Modulation of interactions between myosin and integrins
05/28/1998WO1998022458A1 Multivalent salts of pyridostigmine and related compounds
05/28/1998WO1998022457A1 Aryl and heteroaryl substituted fused pyrrole antiinflammatory agents
05/28/1998DE19648793A1 Neue Benzamide und deren Anwendung New benzamides and their application
05/28/1998CA2271786A1 Multivalent salts of pyridostigmine and related compounds
05/28/1998CA2271767A1 Aryl and heteroaryl substituted fused pyrrole antiinflammatory agents
05/26/1998US5756468 Lyophilized solid drug consists of a compound having botulinum toxicity, stabilizing protein, polysaccharide sugar and thioalkyl compound selected from methionine and cysteine; storage stability