Patents
Patents for A61P 21 - Drugs for disorders of the muscular or neuromuscular system (23,287)
12/1999
12/09/1999WO1999062888A1 Aza-heterocyclic compounds used to treat neurological disorders and hair loss
12/09/1999WO1999062879A1 Ureas and carbamates of n-heterocyclic carboxylic acids and carboxylic acid isosteres
12/09/1999WO1999062506A1 Use of compounds for the elevation of pyruvate dehydrogenase activity
12/09/1999WO1999062505A2 Method for treating neurodegenerative disorders
12/09/1999WO1999006397A3 Pyrrolidine-3-carboxylic acid derivatives and their use as endothelin antagonists
12/09/1999CA2333964A1 Aza-heterocyclic compounds used to treat neurological disorders and hair loss
12/09/1999CA2333960A1 Ureas and carbamates of n-heterocyclic carboxylic acids and carboxylic acid isosteres
12/08/1999EP0962529A1 Synthesis of human procollagens and collagens in recombinant DNA systems
12/08/1999EP0961779A1 SUBSTITUTED AMINO BICYCLIC-$g(b)-LACTAM PENAM AND CEPHAM DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS
12/08/1999CN1237969A Multivalent salts of pyridostigmine and related compounds
12/08/1999CN1237881A Method and compositions for increasing anaerobic working capacity in tissues
12/07/1999US5998460 Phenylcarbamates of (-)-eseroline, (-)-N1-noreseroline and (-)-N1-benzylnoreseroline: selective inhibitors of acetyl and butyrylcholinesterase, pharmaceutical compositions and method of use thereof
12/02/1999WO1999061916A1 Identification of broadly reactive dr restricted epitopes
12/02/1999WO1999061437A1 Novel 2-alkyl substituted imidazole compounds
12/02/1999WO1999061423A1 New heterocyclically substituted amides, their production and their use
12/02/1999CA2332786A1 Identification of broadly reactive dr restricted epitopes
12/02/1999CA2332402A1 Novel 2-alkyl substituted imidazole compounds
12/01/1999EP0788491B1 6-polyfluoroalkoxy and 6-polyfluoroalkyl-2-aminobenzothiazole derivatives
12/01/1999CN1237159A Pure enantiomer basic aryl-cycloalkyl-hydroxycarboxylic acid esters, process for preparing same and their use in medicaments
12/01/1999CN1237105A Reflux inhibitors
11/1999
11/30/1999US5994111 A polypeptide; treatment and diagnosis of respiratory infections, septic arthritis, cardiovascular infections, gastrointestinal infections, toxic shock syndrome; antibiotics
11/30/1999US5994098 G protein coupled receptor gene; treatment of pain, diabetes, eating disorders, asthma; hypotensive/hypertensive agents; parkinson's/huntington's/cardiovascular diseases, ulcers, anticarcinogenic/antiallergens agents; osteoprosis,
11/30/1999US5993816 Methods to inhibit humoral immune responses, immunoglobulin production and B cell activation with 5c8-specific antibodies
11/25/1999WO1999059975A1 Fused tricyclic compounds which inhibit parp activity
11/25/1999WO1999059973A1 Carboxamide compounds, compositions, and methods for inhibiting parp activity
11/25/1999WO1999048507A3 Steroidal saponins for treating alzheimer's disease
11/25/1999CA2332279A1 Carboxamide compounds, compositions, and methods for inhibiting parp activity
11/25/1999CA2332239A1 Fused tricyclic compounds which inhibit parp activity
11/24/1999EP0958362A1 Isolation and use of motoneuronotrophic factors
11/24/1999EP0550703B1 Plant-based medicament for enhancing and controlling the tone of smooth-muscle organs
11/24/1999CN1046713C Tetrahydroisoquinoline compound, pharmaceutical composition containing them and its producing method and use
11/23/1999US5990124 Neuromuscular relaxants
11/23/1999US5990083 Composition for reducing cu/zn superoxide dismutase-1 enzyme degradation by inhibiting multicatalytic protease; treating muscle wasting diseases associated with low superoxide dismutase-1 enzyme activity
11/23/1999US5989866 FGF homologs
11/23/1999US5989822 Diagnosis and treatment of cancer, neurodegenerative and autoimmune diseases; gene expression
11/18/1999WO1999058502A1 Heterocyclic inhibitors of p38
11/18/1999WO1999045949A3 Use of follistatin to modulate gdf-8 and bmp-11
11/18/1999WO1999027098A3 A-33 related antigens and their pharmacological uses
11/17/1999EP0956862A1 Methods of increasing lean tissue mass using ob protein compositions
11/17/1999CN1046519C Oxazolyl- and thiazolylimidazo- and thienodiazepines and use as medicaments
11/16/1999US5985902 Substituted isoxazole for the treatment of inflammation
11/16/1999US5985866 Use of serotonin antagonists for treating fibromyalgia
11/16/1999CA2137811C Dimeric piperidine, tetrahydropyridine and piperazine derivatives
11/11/1999WO1999056785A2 Cell mediated gene delivery using muscle derived cells for treating muscle-and bone-related injury or dysfunction
11/11/1999WO1999056784A2 Inprovements in gene therapy using compositions comprising a polynucleotide and a nuclease inhibitor or interleukin-10
11/11/1999CA2295510A1 Use of a nuclease inhibitor or interleukin-10 (il-10) for the preparation of a therapeutic composition for improving transfection of a polynucleotide into a cell and compositions useful in gene therapy
11/10/1999EP0955301A2 7-aza-bicyclo[2.2.1]-heptane derivatives, their preparation and use according to their affinity for neuronal nicotinic acetylchloline receptors
11/10/1999EP0954532A1 Novel human apoptosis regulator
11/10/1999EP0954338A2 Cationic amphiphile/dna complexes
11/10/1999EP0954317A2 Use of 7 apha-substituted steroids to treat neuropsychiatric, immune or endocrine disorders
11/04/1999WO1999055359A1 Compositions and methods for extending the action of clostridial neurotoxin
11/04/1999WO1999055321A1 Compounds and methods for treating mitochondria-associated diseases
11/04/1999CA2329709A1 Compounds and methods for treating mitochondria-associated diseases
11/04/1999CA2328111A1 Compositions and methods for extending the action of clostridial neurotoxin
11/03/1999EP0953637A2 Acetylcholine receptor
11/03/1999EP0953576A1 Active hedgehog protein conjugate, process for its production and use
11/03/1999CN1233616A Active hedgehog protein conjugate, process for its prodn. and use
11/02/1999USRE36374 1,2,3-triazole and tetrazole substituted piperidine or tetrahydropyridine compounds useful as acetylcholine agonists
11/02/1999US5976837 Secreted proteins and polynucleotides encoding them
10/1999
10/30/1999CA2269221A1 Active hedgehog protein conjugate, process for its production and use
10/28/1999WO1999054320A1 Novel heterocyclically substituted amides with cysteine protease-inhibiting effect
10/28/1999WO1999054304A1 Heterocyclically substituted amides, their production and their use
10/28/1999WO1999054294A1 New substituted amides, their production and their use
10/28/1999WO1999054280A1 Cubane derivatives as metabotropic glutamate receptor antagonists and process for their preparation
10/28/1999WO1999053921A1 Composition comprising l-carnitine or an alkanoyl l-carnitine and nadh and/or nadph
10/28/1999CA2328720A1 Novel heterocyclically substituted amides with cysteine protease-inhibiting effect
10/28/1999CA2328435A1 New substituted amides, their production and their use
10/28/1999CA2328331A1 Composition comprising l-carnitine or an alkanoyl l-carnitine and nadh and/or nadph
10/27/1999EP0951543A1 Human glycine transporter
10/26/1999US5973204 3-demethyl benzo(a)heptalene derivative used as antiinflammatory and muscle relaxant
10/26/1999US5972652 Polynucleotides encoding secreted proteins
10/21/1999WO1999046245A3 PROCESSES FOR THE PREPARATION OF (R)-α- (2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUOROPHENYL)ETHYL]-4-PIPERIDINEMETHANOL
10/21/1999DE19818614A1 New benzamide derivatives useful as cysteine protease inhibitors for treating neurodegenerative diseases, neuronal damage, stroke, cranial trauma, Alzheimer's disease, etc.
10/21/1999DE19817459A1 New heterocyclic amide derivatives useful as cysteine protease inhibitors for treating neurodegenerative diseases, neuronal damage, stroke, cranial trauma, Alzheimer's disease, etc.
10/20/1999EP0950406A2 Remedy for CAG repeat expansion diseases
10/20/1999EP0950046A1 3,4-disubstituted azetidin-2-one derivatives useful as cysteine proteinase regulators
10/20/1999CN1232451A Substd. cyclic amine metalloprotease inhibitors
10/20/1999CN1232399A Inhibitors of cysteine protease
10/20/1999CN1232394A Solid oral dosage forms of valsartan
10/20/1999CN1045769C Process for preparing sulfurous derivs. of imidazole
10/19/1999US5969184 Amide compounds
10/19/1999US5969093 Secreted proteins
10/13/1999EP0948521A1 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function
10/13/1999EP0948496A2 Substituted pyrimidinone and pyridone compounds and methods of use
10/13/1999EP0948495A1 Aryl and heteroaryl substituted fused pyrrole antiinflammatory agents
10/13/1999EP0936912A4 Inhibitors of cysteine protease
10/12/1999US5965423 A polypeptide; diagnosis of cirrhosis, multiple sclerosis, gastrointestinal disorders, respiratory disorders, acquired immune defiency syndrome; antiarthritic/antiischemic/ antiallergens/ antiproliferactive agents
10/12/1999US5965388 Isolated polynucleotides; diagnosis and treatment autoimmune diseases, tissue rejection, allergies, acquired immune deficiency disease; viricides, bactericides and fungicides; anticarcinogenic agents
10/07/1999WO1999050225A1 Aminocyclohexyl ether compounds and uses thereof
10/06/1999EP0947506A1 2-Aza-bicyclo[2.2.1]heptane derivatives and their use as rotamase inhibitors
10/06/1999EP0946733A1 Hsv/aav hybrid amplicon vectors
10/06/1999EP0946562A1 PYRROLO 3,4-$i(D)]PYRIMIDINONE DERIVATIVES AND THEIR USE AS MEDICAMENTS
10/05/1999US5962536 Injectable propofol formulations
10/05/1999US5962532 Therapeutic method with capsaicin and capsaicin analogues
10/05/1999US5962521 Prostate glands disorders
10/05/1999US5962450 Oxazolyl- and thiazolylimidazo-benzo- and thienodiazepines and their use as medicaments
09/1999
09/30/1999WO1999048507A2 Steroidal saponins for treating alzheimer's disease
09/30/1999WO1999048482A2 Smilagenin and anzurogenin-d for the treatment of alzheimer's disease
09/30/1999WO1999038532A3 Methods for the prevention and treatment of fibrosis and sclerosis
09/30/1999WO1999006340A3 Sulfonylamino substituted hydroxamic acid derivatives as metalloprotease inhibitors