Patents
Sitemap › A61 - Medical or veterinary science; Hygiene › A61P - Specific therapeutic activity of chemical compounds or medicinal preparations › A61P 19 - Drugs for skeletal disorders
Patents for A61P 19 - Drugs for skeletal disorders (81,981)
08/1999
08/19/1999CA2318966A1 Biaryl-acetic acid derivatives and their use as cox-2 inhibitors
08/18/1999EP0935963A2 The use of MMP-13 selective inhibitors for the treatment of osteoarthritis and other matrix metalloproteinase-mediated disorders
08/18/1999EP0935657A2 Modified glucocorticoid receptors, glucocorticoid receptors/progesterone receptors hybrids
08/18/1999EP0935465A1 Novel substituted imidazole compounds
08/18/1999EP0935458A1 Compositions containing at least one nucleic acid
08/18/1999EP0796257B1 Malonic acid based matrix metalloproteinase inhibitors
08/18/1999EP0792292B1 Orphan receptor
08/18/1999EP0779808B1 Triphenylethylenes for the prevention and treatment of osteoporosis
08/18/1999CN1226254A Method and composition useful for inhibition of vasculogenesis of alpha, beta medium
08/18/1999CN1226174A Use of proteinase inhibitors for prevention or reduction of bone resorption
08/18/1999CN1225834A Liniment
08/17/1999US5939583 Antiarthritic agents; bone, cardiovascular, brain, nervous system disorders; antitumor and antimetastasis agents
08/17/1999US5939450 N,N-dimethyl-8,8-dipropyl-2-azaspiro 4.5!decane-2-propanamine dimaleate
08/17/1999US5939392 Thrombin inhibitors, anticoagulants and antiinflammatory agents
08/17/1999US5939391 Hemoglobin alpha chain peptide fragments useful for inhibiting stem cell proliferation
08/17/1999CA2136824C Phosponocarboxylate compounds for treating abnormal calcium and phosphate metabolism
08/12/1999WO1999040220A2 Method of screening therapeutic agents
08/12/1999WO1999040201A1 Protein
08/12/1999WO1999040091A1 Bicyclic pyridine and pyrimidine derivatives as neuropeptide y receptor antagonists
08/12/1999WO1999040089A1 Benzothiadiazoles and derivatives
08/12/1999WO1999040088A1 Heteroaryl amidines, methylamidines and guanidines as protease inhibitors, in particular as urokinase inhibitors
08/12/1999WO1999040085A1 Benzofuran-4-carboxamides and their therapeutic use
08/12/1999WO1999040083A2 Bifunctional tryptase inhibitors
08/12/1999WO1999040080A1 Hydroxamic and carboxylic acid derivatives
08/12/1999WO1999040073A2 Tryptase inhibitors
08/12/1999WO1999039724A1 Treatment of bony defects with osteoblast precursor cells
08/12/1999WO1999028344A3 Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment
08/12/1999WO1999000116A3 Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them
08/12/1999CA2321175A1 Method of screening therapeutic agents
08/12/1999CA2321025A1 Heteroaryl amidines, methylamidines and guanidines as protease inhibitors, in particular as urokinase inhibitors
08/12/1999CA2318977A1 Derivatives of benzoxadiazoles, benzothiadiazoles, benzotriazoles and quinoxalines
08/12/1999CA2317478A1 Benzofuran-4-carboxamides and their therapeutic use
08/12/1999CA2317476A1 Hydroxamic and carboxylic acid derivatives
08/11/1999EP0935000A2 Orphan receptor
08/11/1999EP0934937A1 Azole derivatives as superoxide radical inhibitor
08/11/1999EP0934305A1 Integrin antagonists
08/11/1999EP0934304A1 2-pyrimidineamine derivatives and processes for their preparation
08/11/1999EP0934300A1 The preparation and use of ortho-sulfonamido heteroaryl hydroxamic acids as matrix metalloproteinase and tace inhibitors
08/11/1999EP0934299A1 NOVEL $i(CIS)-3,4-CHROMAN DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES
08/11/1999EP0934298A1 NOVEL (+)-ENANTIOMERS OF $i(CIS)-3,4-CHROMAN DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES
08/11/1999EP0934297A1 NOVEL $i(cis)-3,4-CHROMAN DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES
08/11/1999EP0934292A1 Metalloproteinase inhibitors
08/11/1999EP0934291A1 Protease inhibitors
08/11/1999EP0934267A1 $g(a)-AMINO SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE INHIBITORS
08/11/1999EP0934264A1 Pyrrolidinyl and pyrrolinyl ethylamine compounds as kappa agonists
08/11/1999EP0934259A1 Beta-sulfonamido hydroxamic acids as matrix metalloproteinase and tace inhibitors
08/11/1999EP0934068A1 Compounds and methods
08/11/1999CN1225637A Pyrrole triazines and pyrimidines
08/11/1999CN1225622A Substituted oxobutyric acids as matrix metalloprotease inhibitor
08/11/1999CN1225620A Substituted 4-arylbutyric acid derivatives as matrix metalloprotease inhibitors
08/11/1999CN1225589A Purified extract of harpagophytum procumbens and/or harpagophytum zeyheri dence, process for its prodn. and its use
08/11/1999CN1225367A Bond partner, and use for sieving inhibitor and diagnosis and treatment of disease
08/11/1999CN1225360A Substituted imidazolidine derivatives, their prepn., their use and pharmaceutical prepn. comprising them
08/10/1999US5936133 2-alkylidene-19-nor-vitamin D compounds
08/10/1999US5936089 Dipeptides which promote release of growth hormone
08/10/1999US5935996 Composition for stimulating osteogenesis and preventingreduction of bone salt
08/10/1999US5935947 Imidobisphosphoric acids, and use thereof
08/10/1999US5935931 Human apoptosis-related calcium-binding protein
08/10/1999US5935852 The present invention relates to a family of proteins designated as cerberus, which appears to be a pioneer protein, with a 9 cysteine residue pattern, which is present in the embryo.
08/10/1999US5935814 G-protein coupled receptor family polypeptides, referred to as hfgan72y, altered nucleic acid seqences encoding it and recombinant materials and methods for its production; use in design of protocols and treatment of various infections
08/10/1999US5935602 Dosage forms of risedronate
08/09/1999CA2245999A1 Novel compounds
08/05/1999WO1999038998A1 Methods of identifying modulators of kinases responsive to stress
08/05/1999WO1999038850A1 Novel alkanoic acids and their use in medicine, process for their preparation and pharmaceutical compositions containing them
08/05/1999WO1999038843A1 Hydroxamic and carboxylic acid derivatives
08/05/1999WO1999028493A3 Method for identifying inhibitors of g-protein coupled receptor hibef51
08/05/1999WO1999024398A3 Urea derivatives and their use as integrin inhibitors
08/05/1999WO1999021860B1 Phenanthroline derivatives
08/05/1999WO1999011292A9 Compositions and methods for treating arthritis utilizing gene therapy
08/05/1999CA2317459A1 Methods of identifying modulators of kinases responsive to stress
08/04/1999EP0933367A1 Novel acylguanidine derivates as inhibitors of bone resorption and as vitronectin receptor antagonists
08/04/1999EP0932600A2 SULFONAMIDE SUBSTITUTED ASPARTIC ACID INTERLEUKIN-1$g(b) CONVERTING ENZYME INHIBITORS
08/04/1999CN1225085A Substituted pyridines as selective cyclooxygenase-2 inhibitors
08/04/1999CN1225082A Polyhydroxyphenol derivatives and preventive and therapeutic agents for bone and cartilage diseases containing the same
08/04/1999CN1224718A Thiazole derivatives
08/03/1999US5932716 Disclosed herein are methods and compositions for identifying morphogen analogs.
08/03/1999US5932598 Prodrugs of benzenesulfonamide-containing COX-2 inhibitors
08/03/1999US5932595 Antiarthritic agent; multiple sclerosis; osteoporosis; respiratory system disorders; skin disorders; antiulcer agent
08/03/1999US5932576 3(5)-heteroaryl substituted pyrazoles as p38 kinase inhibitors
08/03/1999US5932565 Vitamin D analogues
08/03/1999US5932259 Basic peptide fraction is obtained by hydrolyzing the basic protein fraction with a protease. useful for treating or preventing bone diseases such as osteoporosis.
08/03/1999US5932216 Antibodies to bone morphogenetic protein-10 (BMP-10)
07/1999
07/29/1999WO1999037780A1 Expression of the insl4 gene in human embryonic bone tissues and applications
07/29/1999WO1999037760A1 Inhibition of cytokine production
07/29/1999WO1999037682A2 Antibodies against human il-12
07/29/1999WO1999037674A1 Secreted proteins and polynucleotides encoding them
07/29/1999WO1999037668A1 Thrombin inhibitors
07/29/1999WO1999037651A1 Chemokine receptor antagonists and methods of use therefor
07/29/1999WO1999037625A1 2,3,4,5-tetrahydro-1h-[1,4]-benzodiazepine-3-hydroxamic acids as matrix metalloproteinase inhibitors
07/29/1999WO1999037621A1 Novel sulfonamide derivatives as inhibitors of bone resorption and as inhibitors of cell adhesion
07/29/1999WO1999037619A1 Chemokine receptor antagonists and methods of use therefor
07/29/1999WO1999037617A1 Chemokine receptor antagonists and methods of use therefor
07/29/1999WO1999037604A2 Dialkyl ureas as calcitonin mimetics
07/29/1999WO1999037318A1 Histone containing composition to treat rheumatoid arthritis
07/29/1999WO1999037314A1 Sea cucumber carotenoid lipid fraction products and methods of use
07/29/1999WO1999037304A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS
07/29/1999WO1999037301A1 New use for pain management
07/29/1999CA2319077A1 Chemokine receptor antagonists and methods of use therefor
07/29/1999CA2319076A1 Expression of the insl4 gene in human embryonic bone tissues and applications
07/29/1999CA2318303A1 Secreted proteins and polynucleotides encoding them
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