Patents for A61P 19 - Drugs for skeletal disorders (81,981)
09/1999
09/28/1999US5959123 Reacating substituted amino acid with 3-amino-4-substituted-azetidine-2-one compound to form 3, 4-disubstituted-azetidine-2-one compound; useful for treating muscular dystrophy, arthritis, viral and parasitic infections
09/28/1999US5959103 Naphthofluorene compounds, intermediates, compositions, and methods
09/28/1999US5958954 2,2-dialkyl-4-aryl-substituted benzopyran and benzothiopyran derivatives
09/28/1999US5958917 Benzofluorene compounds, intermediates, compositions, and methods
09/28/1999US5958908 Sodium alendronate preparation for local administration
09/28/1999US5958882 Compounds that inhibit T cell proliferation and methods using the same
09/28/1999US5958731 Cell junction PDZ protein
09/28/1999US5958710 The receptor may be useful in isolating molecules for the treatment of disorders such as prostate cancer, benign prostatic hyperplasia, osteoporosis or cardiovascular disorders and in the testing of substances for estrogenic and
09/28/1999US5958418 External herbal composition for treating muscle aches and joint pain
09/23/1999WO1999047708A1 Antisense modulation of pecam-1
09/23/1999WO1999047707A1 Antisense modulation of lfa-3
09/23/1999WO1999047677A2 Polypeptides homologous to vegf and bmp1
09/23/1999WO1999047550A1 Novel matrix metalloproteinase inhibitors and down-regulators
09/23/1999WO1999047547A1 Cinnamic acid derivatives having cell adhesion modulating activity
09/23/1999WO1999047545A2 Inhibitors of caspases
09/23/1999WO1999047538A1 Cytokine receptor common gamma chain like
09/23/1999WO1999047529A1 Heterocyclic signal transduction inhibitors, compositions containing them
09/23/1999WO1999047524A1 Novel heterocyclic compounds
09/23/1999WO1999047512A1 2-(2,6-dioxopiperidin-3-yl)isoindoline derivatives, their preparation and their use as inhibitors of inflammatory cytokines
09/23/1999WO1999047156A2 Compositions for modulating cell differentiation comprising a lipid and a morphogen
09/23/1999WO1999047149A1 Utilization of extracts from iris plants, cimicifuga racemosa and tectorigenin as an estrogen-like organ-selective medicament without uterotropic effects
09/23/1999WO1999047132A2 Heterocyclic compounds, their production and use as tachykinin receptor antagonists
09/23/1999WO1999033859A9 Novel anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
09/23/1999WO1999032620A9 Insulin-like growth factor binding protein fragments and the utilization thereof
09/23/1999CA2323078A1 Compositions for modulating cell differentiation comprising a lipid and a morphogen
09/23/1999CA2322742A1 Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment
09/23/1999CA2321155A1 Heterocyclic compounds, their production and use as tachykinin receptor antagonists
09/23/1999CA2319493A1 Heterocyclic signal transduction inhibitors, compositions containing them
09/22/1999EP0943616A1 Substituted imidazole derivatives and their use as cytokine inhibitors
09/22/1999EP0943003A1 Insulin-like growth factor i (igf-i) expression system and methods of use
09/22/1999EP0942974A2 Secreted proteins and polynucleotides encoding them
09/22/1999EP0942960A1 Promotion of regeneration of organized tissues
09/22/1999EP0942925A2 INHIBITORS OF INTERLEUKIN-1$g(b) CONVERTING ENZYME
09/22/1999EP0942902A2 Novel immunotherapeutic imides/amides
09/22/1999EP0942740A2 Combination therapy using a tnf binding protein for treating tnf-mediated diseases
09/22/1999EP0726764B1 Multilamellar liposomal arachidonic acid metabolite formulations
09/22/1999CN1229412A Inhibitors of interleukin-1'beta' converting emzyme
09/22/1999CN1229407A Bi-aromatic compounds and pharmaceutical and cosmetic compositions containing the same
09/22/1999CN1229083A Novel phosphononosulfonate compounds and its pharmaceutical compositions
09/22/1999CN1228994A Pharmaceutical composition of hedgehog proteins and use thereof
09/22/1999CN1228971A Health-care mattress with functions dispelling wind and clearing away cold, removing dampness and warming kidney
09/22/1999CN1228958A Radix aconiti kunsezoffii nail element soft capsule and production method thereof
09/21/1999US5955608 Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents
09/21/1999US5955574 Analogs of parathyroid hormone
09/21/1999US5955492 Carboxylic acid indole inhibitors of chemokines
09/21/1999US5955476 Substituted 2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing inflammatory cytokine levels
09/21/1999US5955443 Treatment and diagnosis of diseases or disorders amenable to treatment through modulation of expression of a nucleic acid encoding a platelet endothelial cell adhesion molecule-1 (pecam-1; also known as cd31 antigen or endocam) protein are
09/21/1999US5955365 Introducing polynucleotides into cells
09/21/1999US5955309 Polynucleotide encoding G-protein coupled receptor (H7TBA62)
09/21/1999US5955308 cDNA clone HEAOD54 that encodes a human 7-transmembrane receptor
09/16/1999WO1999046366A1 Uses for humane non-autologous mesenchymal stem cells
09/16/1999WO1999046364A1 Vascular endothelial growth factor 2
09/16/1999WO1999046289A1 31 human secreted proteins
09/16/1999WO1999046283A1 Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
09/16/1999WO1999046281A2 Novel polypeptides and nucleic acids encoding the same
09/16/1999WO1999046272A1 Serine peptidase modulators
09/16/1999WO1999046268A1 MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases)
09/16/1999WO1999046248A1 1,2-diazepane derivatives as interleukin-1beta converting enzyme inhibitors
09/16/1999WO1999046237A1 Modulators of protein tyrosine phosphatases
09/16/1999WO1999045927A1 Vitronectin receptor antagonists
09/16/1999WO1999045923A1 Methods of inhibiting bone resorption
09/16/1999WO1999045919A1 Phenanthrofuran derivatives
09/16/1999WO1999029878A3 Methods of producing anti-angiogenic proteins: endostatin, angiostatin or restin, using a pichia yeast expression system
09/16/1999CA2323493A1 Modulators of protein tyrosine phosphatases (ptpases)
09/16/1999CA2323448A1 Methods of inhibiting bone resorption
09/16/1999CA2323208A1 Vitronectin receptor antagonists
09/16/1999CA2322962A1 Phenanthrofuran derivatives
09/16/1999CA2322748A1 Vascular endothelial growth factor 2
09/16/1999CA2322728A1 31 human secreted proteins
09/16/1999CA2321026A1 Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
09/15/1999EP0941992A1 Ipriflavone preparation process
09/15/1999EP0941330A1 Therapeutic compositions and methods for treating disease states with myeloid progenitor inhibitory factor-1 (mpif-1), monocyte colony inhibitory factor (m-cif), and macrophage inhibitory factor-4 (mip-4)
09/15/1999EP0941323A1 Bone morphogenetic protein-16 (bmp-16) compositions
09/15/1999EP0941253A1 New butyric esters with antiproliferative activity and the pharmaceutical compositions containing them
09/15/1999EP0941247A2 Peptide compounds useful for modulating fgf receptor activity
09/15/1999EP0941242A2 Secreted proteins and polynucleotides encoding them
09/15/1999EP0941115A1 Use of growth hormone or a growth hormone secretagogue for promoting bone formation
09/15/1999CN1228780A Phosphinic acid amides as matrix metalloprotease inhibitors
09/15/1999CN1228779A Spirocyclic metalloprotease inhibitors
09/15/1999CN1228773A Heterocyclic metalloprotease inhibitors
09/15/1999CN1228772A Heterocyclic metalloprotease inhibitors
09/15/1999CN1228767A Bidentate metalloprotease inhibitors
09/15/1999CN1228758A Haphthyl compounds, intermediates, compositions and methods of use
09/15/1999CN1228702A Transdermal therapeutical approach involving combination of active substances containing oestriol
09/15/1999CN1228697A Method for in vivo reduction of iron levels and compositions useful therefor
09/14/1999US5952483 Human IκB-β
09/14/1999US5952381 Para-substituted phenylene derivatives
09/14/1999US5952350 Naphthyl compounds and compositions, as estrogen receptor binding agents
09/14/1999US5952322 Method of reducing tissue damage associated with non-cardiac ischemia using glycogen phosphorylase inhibitors
09/14/1999CA2159449C Oesteoblast growth stimulating composition containing pdgf and vitamin d
09/10/1999WO1999045031A2 Cd147 binding molecules as therapeutics
09/10/1999WO1999045027A1 Thiadiazole compounds useful as inhibitors of cysteine activity dependent enzymes
09/10/1999WO1999045024A1 Cholenic acid amides and pharmaceutical compositions thereof
09/10/1999WO1999045009A1 Heterocyclo-substituted imidazopyrazine protein tyrosine kinase inhibitors
09/10/1999WO1999044995A1 Novel pyridazine derivatives and drugs containing the same as the active ingredient
09/10/1999WO1999044994A1 Meta-azacyclic amino benzoic acid compounds and derivatives thereof being integrin antagonists
09/10/1999WO1999044989A1 Matrix metalloproteinase inhibitors
09/10/1999CA2322838A1 Thiadiazole compounds useful as inhibitors of cysteine activity dependent enzymes
09/10/1999CA2322749A1 Cd147 binding molecules as therapeutics
09/10/1999CA2322207A1 Meta-azacyclic amino benzoic acid compounds and derivatives thereof being integrin antagonists