Patents for A61P 19 - Drugs for skeletal disorders (81,981)
01/2000
01/26/2000EP0973792A1 16-hydroxy-11-(substituted phenyl)-estra-4,9-diene derivatives
01/26/2000EP0973790A1 Estra-5(10),7-dienes with estrogenic activity
01/26/2000EP0973789A1 Novel phosphate compounds and their use as medicaments
01/26/2000EP0973748A1 Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses
01/26/2000EP0973733A1 Bis-sulfonomides hydroxamic acids as mmp inhibitors
01/26/2000EP0973730A1 Calcilytic compounds
01/26/2000EP0973550A1 Antagonistic anti-avb3 integrin antibodies
01/26/2000EP0973539A2 Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation
01/26/2000EP0973519A1 Inclusion complexes in aqueous solution
01/26/2000EP0973513A1 Compositions and methods for treating bone deficit conditions
01/26/2000EP0973512A1 N-hydroxy-2-(alkyl, aryl or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors
01/26/2000EP0973392A1 Sulfonyl divalent aryl or heteroaryl hydroxamic acid compounds
01/26/2000CN1242224A Medicine specially for treating caput femoris necrosis, and method for preparing same
01/26/2000CN1048726C Substituted 4-phenyl thiazole derivant, prepn. and medicine compositions thereof
01/25/2000US6017908 3-EPI vitamin D2 compounds and uses thereof
01/25/2000US6017907 Structural analogues of vitamin D
01/25/2000US6017885 IGF/IGFBP complex for promoting bone formation and for regulating bone remodeling
01/25/2000US6017763 G-beta-gamma regulated phosphatidylinositol-3' kinase
01/25/2000US6017531 An extracellular neutral protease and a stabilizer of glyceryl cocoate as a wound healing agent and for debriding necrotic tissue; storage stable enzyme activity at room temperature; burns; cutaneous ulcers; pressure necroses incisional,
01/20/2000WO2000002912A2 Disintegrin homologs
01/20/2000WO2000002905A2 Methods for accelerating bone and cartilage growth and repair
01/20/2000WO2000002904A1 Matrix metalloproteinase inhibitors containing aminomalonic acid derivatives and peptide backbone modified derivatives thereof
01/20/2000WO2000002871A1 Novel angiogenesis inhibitors
01/20/2000WO2000002870A1 Antiviral macrocyclic compounds
01/20/2000WO2000002839A1 Cytokine production and tyrosine kinase inhibitors
01/20/2000WO2000002553A1 Compositions and methods for treating and preventing bone diseases using tocotrienols
01/20/2000WO2000002548A2 Inhibitors of proteasomal activity for stimulating bone and hair growth
01/20/2000WO1999059526A3 Protease inhibitors
01/20/2000WO1999053943A3 Therapeutic angiogenic factors and methods for their use
01/20/2000WO1999051742A3 Dadd, death activator death domain protein
01/20/2000DE19833786A1 New diphenyl-benzocycloheptene derivatives, are tissue-selective estrogens and antiestrogens useful e.g. for treating osteoporosis or hormone-dependent tumors or in hormone replacement therapy
01/20/2000DE19831710A1 New diacyl-hydrazine derivatives, are integrin inhibitors useful for treating e.g. thrombosis, cardiac infarction, tumors, osteoporosis, inflammation or infection
01/20/2000CA2336848A1 Novel angiogenesis inhibitors
01/20/2000CA2332311A1 Disintegrin homologs
01/19/2000EP0972837A2 Ubiquitin specific protease like protein
01/19/2000EP0972780A1 Il-6 antagonist peptides
01/19/2000EP0972762A2 Novel structural analogues of vitamin D
01/19/2000EP0972031A1 Procollagen assembly
01/19/2000EP0972026A2 Secreted proteins and polynucleotides encoding them
01/19/2000EP0971955A1 Secreted proteins
01/19/2000EP0971950A2 Secreted proteins and polynucleotides encoding them
01/19/2000EP0971948A2 Inhibitors for urokinase receptor
01/19/2000EP0971921A1 2-aryl-naphthyridin-4-ones as antitumor agents
01/19/2000EP0971917A1 Thiazolidinedione and oxazolidinedione derivatives having antidiabetic, hypolipidaemic and antihypertensive properties
01/19/2000EP0971908A1 Il-8 receptor antagonists
01/19/2000EP0971895A1 Hydroxamic acids substituted by heterocycles useful for inhibition of tumor necrosis factor
01/19/2000EP0971894A1 Nicotinamide derivatives
01/19/2000EP0971888A1 2-alkyl-19-nor-vitamin d compounds
01/19/2000EP0971887A1 Metalloproteinase inhibitors
01/19/2000EP0971883A1 Retinoid-like compounds
01/19/2000EP0971719A1 Therapeutic combination of mineral and vitamin in units of liquid preparation for oral administration
01/19/2000EP0971712A1 Compositions for the inhibition of bone resorption
01/19/2000EP0971588A1 Novel cannabinoid receptor modulators
01/19/2000EP0625989B1 Dna sequences encoding novel growth/differentiation factors
01/19/2000CN1241999A Vitamin D3 derivatives
01/18/2000US6015912 Treating arthritis, cancer, cardiovascular disorders, skin disorders, ocular disorders, inflammation, gum disease
01/18/2000US6015812 N-(arylsulphonyl)amino acid derivatives having bradykinin receptor affinity
01/18/2000US6015790 Methods and compositions for treating rheumatoid arthritis
01/18/2000CA2136818C Sulfur-containing phosphonate compounds for treating abnormal calcium and phosphate metabolism
01/18/2000CA2001124C Treatment of hypertension
01/18/2000CA2001123C Treatment of osteoporosis
01/13/2000WO2000001851A1 Antisense oligonucleotides targeted to il-15
01/13/2000WO2000001690A1 Cinnamic acid derivatives as cell adhesion molecules
01/13/2000WO2000001427A1 Bone cement with antimicrobial peptides
01/13/2000WO2000001386A1 Farnesyl protein transferase inhibitors for treating arthropathies
01/13/2000WO1999055353A3 Protein formulations
01/13/2000WO1999050252A3 Barbituric acid derivative and preventive and therapeutic agent for bone and cartilage containing the same
01/13/2000CA2336030A1 Bone cement with antimicrobial peptides
01/13/2000CA2332699A1 Antisense oligonucleotides targeted to il-15
01/12/2000EP0970694A2 Use of carprofen and derivatives therof for treating or preventing articular degeneration
01/12/2000EP0970208A1 Sp$g(a): A SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING POLYPEPTIDE, AND MONOCLONAL ANTIBODIES THERETO
01/12/2000EP0970111A2 Secreted proteins and polynucleotides encoding them
01/12/2000EP0970109A2 Secreted proteins and polynucleotides encoding them
01/12/2000EP0970047A1 2-alkylidene-19-nor-vitamin d compounds
01/12/2000EP0970046A1 N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors
01/12/2000EP0969859A1 The use of proteins extractable from animal organs for the preparation of medicaments for the treatment of pathological conditions characterized by hyperproduction of tumor necrosis factor (tnf)
01/12/2000EP0969849A1 Stable solid preparation containing vitamin d3 and tricalcium phosphate
01/12/2000EP0639079B1 Methods for treating interleukin-1 and tumor necrosis factor mediated diseases
01/12/2000CN1241177A Substed. 4-biphenyl-4-hydroxybutyric acid derivs. as matrix metalloprotease inhibitors
01/12/2000CN1240647A Use of calcium L-threonate in prevention and inhibition of osteoporosis and rickets
01/11/2000US6013792 Matrix metalloprotease inhibitors
01/11/2000US6013497 Polynucleotide sequence that codes a polypeptide; bactericides
01/11/2000US6013476 DNA encoding tumor necrosis related receptor TR7
01/11/2000US6013455 Polynucleotides which identify and encode protein kinase homologs, amino acid sequences encoding pkh; methods of pkh production with expression vectors; hybridizes under given conditions
01/11/2000US6013454 Kinesin-like motor protein
01/06/2000WO2000000599A2 Composition for the induction of apoptosis in target cells
01/06/2000WO2000000596A1 3'-exonuclease, production and use thereof
01/06/2000WO2000000510A2 Growth factor modulators
01/06/2000WO2000000477A1 Non-peptidyl inhibitors of vla-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases
01/06/2000WO2000000473A1 Carboxylic and hydroxamic acid compounds inhibiting metalloproteases, method for preparing same and pharmaceutical compositions containing them
01/06/2000WO2000000465A1 Hydrazine derivatives
01/06/2000WO2000000201A1 BICYCLIC sPLA2 INHIBITORS
01/06/2000WO2000000200A1 A PHARMACEUTICAL COMBINATION COMPRISING A COX-2 INHIBITOR AND A iNOS INHIBITOR
01/06/2000WO2000000180A1 Utilization of growth factors for the production of medicaments
01/06/2000WO2000000161A2 Methods for identification of tef-3 interacting factors
01/06/2000CA2336625A1 Non-peptidyl inhibitors of vla-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases
01/06/2000CA2335921A1 Carboxylic and hydroxamic acid compounds inhibiting metalloproteases, method for preparing same and pharmaceutical compositions containing them
01/06/2000CA2335448A1 Bicyclic spla2 inhibitors
01/06/2000CA2335245A1 Hydrazine derivatives
01/06/2000CA2334515A1 A pharmaceutical combination comprising a cox-2 inhibitor and a inos inhibitor