Patents for A61P 19 - Drugs for skeletal disorders (81,981)
05/1999
05/20/1999WO1999024460A2 Dipeptide nitriles
05/20/1999WO1999024423A1 Piperidine derivatives and their use as tachykinin antagonists
05/20/1999WO1999024420A1 Pyrimidinone compounds and pharmaceutical compositions containing them
05/20/1999WO1999024416A1 Aminothiazole inhibitors of cyclin dependent kinases
05/20/1999WO1999024408A1 Heterocyclic compounds having mmp and tnf inhibitory activity
05/20/1999WO1999024404A1 Substituted pyridine compounds as anti-inflammatory agents
05/20/1999WO1999024399A1 Hydroxamic and carboxylic acid derivatives having mmp and tnf inhibitory activity
05/20/1999WO1999024398A2 Urea derivatives and their use as integrin inhibitors
05/20/1999WO1999024035A1 Benzothiazole protein tyrosine kinase inhibitors
05/20/1999WO1999015160A3 Use of 6,7-substituted 2-aminotetralines suitable for preparing pharmaceutical composition for the therapeutic treatment of inflammatory and/or autoimmune pathologies
05/20/1999WO1999007736A3 Lipoprotein-regulating medicaments
05/20/1999CA2309319A1 Benzothiazole protein tyrosine kinase inhibitors
05/20/1999CA2309177A1 Pyrimidinone compounds and pharmaceutical compositions containing them
05/20/1999CA2309162A1 Piperidine derivatives and their use as tachykinin antagonists
05/20/1999CA2309007A1 Secreted proteins and polynucleotides encoding them
05/20/1999CA2308716A1 Urea derivatives and their use as integrin inhibitors
05/20/1999CA2308359A1 Hydroxamic and carboxylic acid derivatives having mmp and tnf inhibitory activity
05/20/1999CA2308358A1 Heterocyclic compounds having mmp and tnf inhibitory activity
05/19/1999EP0916729A2 Novel reductase
05/19/1999EP0916663A1 18Beta, 19Beta-diacetyloxy-18Alpha, 19Alpha-epoxy-3,13(16), 14-clerodatrien-2-one (Esculentin A) and 18Beta, 19Beta-diacetyloxy-18Alpha, 19Alpha-epoxy-3, 12, 14-clerodatrien-2Beta-isovaleryloxy-6Beta, 7Alpha-diol (Esculentin B), a process for their preparation, and their use in the manufacture of medicaments
05/19/1999EP0915911A1 Parathyroid hormone analogues for the treatment of osteoporosis
05/19/1999EP0915843A1 Azetidinone derivatives for the treatment of atheroscleroses
05/19/1999EP0915823A1 Bi-aromatic compounds, pharmaceutical and cosmetic compositions containing same and uses
05/19/1999EP0915709A1 The use of proteinase inhibitors for prevention or reduction of bone resorption
05/19/1999EP0915651A1 Il-8 receptor antagonists
05/19/1999CN1216994A Apoptosis inducing molecule II
05/19/1999CN1216993A Alkyl-4-silyl-phenols and esters thereof as anti-atherosclerotic agent
05/19/1999CN1216978A New vitamin-D derivatives with carbo- or heterocyclic substitutents at C-25, process for the prodn. intermediate products and their use for producing medicaments
05/19/1999CN1043424C Quaternary nitrogen contg. phosphonate compounds, pharmaceutical compositions and pharmaceutical use
05/18/1999US5905076 Treatment of muscular dystrophy, arthritis, myocardial infarction, alzheimer's disease, bacterial infection, common cold, osteoporosis or cancer metastasis
05/18/1999US5905074 Skin disorders, antitumor agents, vitamin d derivatives
05/14/1999WO1999023208A2 RIBOZYMES TARGETED TO IL-15 mRNA
05/14/1999WO1999023087A1 Diaryl-5-alkyl-5-methyl-2(5h)-furanones as selective cyclooxygenase-2 inhibitors
05/14/1999WO1999023076A1 Therapeutically active compounds based on indazole bioisostere replacement of catechol in pde4 inhibitors
05/14/1999WO1999023063A1 Substituted anilides
05/14/1999WO1999022716A1 Topical compositions for nsai drug delivery
05/14/1999WO1999012561A3 FRACTURE HEALING USING PTHrP ANALOGS
05/14/1999WO1999007351A3 Indole derivatives and their use as mcp-1 antagonists
05/14/1999WO1998051289A3 Monoesters of probucol for the treatment of cardiovascular and inflammatory disease
05/14/1999CA2309175A1 Therapeutically active compounds based on indazole bioisostere replacement of catechol in pde4 inhibitors
05/14/1999CA2308018A1 Ribozymes targeted to il-15 mrna
05/14/1999CA2307853A1 Diaryl-5-alkyl-5-methyl-2(5h)-furanones as selective cyclooxygenase-2 inhibitors
05/12/1999EP0914456A1 Gene expression in monocytes and macrophages
05/12/1999EP0914432A2 Secreted proteins and polynucleotides encoding them
05/12/1999EP0914431A2 Truncated soluble tumor necrosis factor type-i and type-ii receptors
05/12/1999EP0914345A1 Antibodies binding to monocyte chemoattractant protein 1 (mcp-1) receptor (ccr2)
05/12/1999EP0914322A1 New indolyl and benzofuranyl carboxamides as inhibitors of nitric oxide production
05/12/1999EP0914319A1 Diarylalkyl cyclic diamine derivatives as chemokine receptor antagonists
05/12/1999CN1216551A Novel peptides suitable for use in antigen specific immunosuppressive therapy
05/12/1999CN1216544A Novel N-7-heterocyclyl pyrrolo [2,3-D] pyridines and their use
05/12/1999CN1216472A A pharmaceutical formulation containing growth hormone, an amino acid and a non-ionic detergent
05/11/1999US5902800 Dextran formulations and method for treatment of inflammatory joint disorders
05/06/1999WO1999022243A1 148 human secreted proteins
05/06/1999WO1999021860A1 Phenanthroline derivatives
05/06/1999WO1999021835A1 QUINOLINE DERIVATIVES AS H+-ATPase INHIBITORS AND AS BONE RESORPTION INHIBITORS
05/06/1999WO1999021559A1 MORPHOLINO-N-ETHYL ESTER PRODRUGS OF INDOLE sPLA2 INHIBITORS
05/06/1999WO1999021557A1 Antagonists of gonadotropin releasing hormone
05/06/1999WO1999021546A1 N,N-DIETHYLGLYCOLAMIDO ESTER PRODRUGS OF INDOLE sPLA2 INHIBITORS
05/06/1999WO1999015493A8 9,10-dihydro-9,10-ethanoanthracene derivatives as phospholipase inhibitors
05/06/1999WO1999013054A3 Method for the treatment or diagnosis of human pathologies with disseminated or difficult to access cells or tissues
05/06/1999EP0913481A2 Staphylococcus aureus member of the DEAD-type ATP-dependent RNA helicases (dbpB)
05/06/1999EP0913155A2 Pharmaceutical formulation for treating liver disorders
05/06/1999EP0912741A2 T-cell selective interleukin-4 agonists
05/06/1999EP0912735A2 Secreted proteins and polynucleotides encoding them
05/06/1999EP0912560A1 Indole derivatives for the treatment of osteoporosis
05/06/1999EP0912558A1 Substituted indazole derivatives and their use as phosphodiesterase (pde) type iv and tumor necrosis factor (tnf) inhibitors
05/06/1999EP0912543A1 Crystalline (-)-3r,4r-trans-7-methoxy-2,2-dimethyl-3-phenyl-4-[4- 2-(pyrrolidin-1-yl)ethoxy]phenyl chromane, hydrogen fumarate
05/06/1999EP0912539A1 Heteroaromatic pentadienoic acid derivatives useful as inhibitors of bone resorption
05/06/1999EP0912518A1 Substituted pyridines as selective cyclooxygenase-2 inhibitors
05/06/1999EP0912511A1 5-indolyl-2,4-pentadienoic acid derivatives useful as inhibitors of bone resorption
05/06/1999EP0912505A1 Il-8 receptor antagonists
05/06/1999EP0912487A1 Substituted oxobutyric acids as matrix metalloprotease inhibitors
05/06/1999EP0912204A2 Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone using functional barrier
05/06/1999EP0912184A1 Use of k-252a derivative for the treatment of peripheral or central nerve disorders, and cytokine overproduction
05/06/1999CA2309135A1 N,n-diethylglycolamido ester prodrugs of indole spla2 inhibitors
05/06/1999CA2308443A1 Morpholino-n-ethyl ester prodrugs of indole spla2 inhibitors
05/06/1999CA2308069A1 Antagonists of gonadotropin releasing hormone
05/06/1999CA2307320A1 148 human secreted proteins
05/05/1999CN1216063A IL-6 mutein
05/05/1999CN1216043A Substd. benzenesulfonamide derivs as prodrugs of COX-2 inhibitors
05/05/1999CN1215611A Medicine for treatment of ischemic necrosis of fermoral head
05/04/1999US5900430 Cytokine inhibitors
05/04/1999US5900255 Material for prevention and treatment of osteoporosis
04/1999
04/29/1999WO1999020646A1 Estra-1,3,5(10)-triene-7alpha-thioethers
04/29/1999WO1999020634A1 Novel methylenebisphosphonic acid derivatives
04/29/1999WO1999020624A1 Bicyclic kinase inhibitors
04/29/1999WO1999020614A1 Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them
04/29/1999WO1999020608A1 Isoquinolines as urokinase inhibitors
04/29/1999WO1999020601A1 α-ARYL-N-ALKYLNITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
04/29/1999CA2308773A1 Estra-1,3,5(10)-triene-7alpha-thioethers
04/29/1999CA2306870A1 Bicyclic kinase inhibitors
04/29/1999CA2306080A1 Novel methylenebisphosphonic acid derivatives
04/29/1999CA2305798A1 .alpha.-aryl-n-alkylnitrones and pharmaceutical compositions containing the same
04/28/1999EP0911633A1 A method of identifying agonists and antagonists for tumor necrosis related receptors TR1, TR3 and TR5
04/28/1999EP0911402A2 PyrR homolog from Staphylococcus aureus
04/28/1999EP0911399A2 A kringle-related clone, HTHBZ47
04/28/1999EP0911342A1 Novel protein and process for producing the same
04/28/1999EP0911331A2 Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
04/28/1999EP0911321A2 Compounds for the treatment of osteoporosis
04/28/1999EP0911319A1 Malonic acid based matrix metalloproteinase inhibitors