Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
08/1997
08/19/1997US5658565 Encoding of protein by nucleic acid transferred to cells in vascular occlusion site; drug delivery
08/14/1997WO1997029213A1 Coding sequences of the human brca1 gene
08/14/1997WO1997029202A1 Vectors and methods for providing cells with additional nucleic acid material integrated in the genome of said cells
08/14/1997WO1997029201A2 Retroviral vector for the gene transfer of an il6 antagonist in human haematopoietic stem cells
08/14/1997WO1997029196A1 Variants of thymidine kinase, related nucleic acids sequences and their use in genic therapy
08/14/1997WO1997029195A2 Human cancer antigen of tyrosinase-related protein 1 and 2 and genes encoding same
08/14/1997WO1997029189A1 Human neuronal attachment factor-1
08/14/1997WO1997029183A2 Methods and compositions for transforming dendritic cells and activating t cells
08/14/1997WO1997029180A1 Diabetes therapy
08/14/1997WO1997029119A1 Fhit proteins and nucleic acids and methods based thereon
08/14/1997WO1997029113A2 Process for preparing purified nucleic acid and the use thereof
08/14/1997WO1997028818A1 Novel methods of vaccination and vaccines therefore comprising a nucleic acid encoding a first epitope and a peptide containing a second epitope
08/14/1997WO1997028817A1 Receptor ligand-facilitated delivery of biologically active molecules
08/14/1997DE19704979A1 Retroviral vector for expressing interleukin-6 antagonist in human haematopoietic stem cells
08/14/1997DE19605105A1 Neue Sonde zur Früherkennung von epithelialen Dysplasien des mehrschichtigen Plattenepithels sowie zur Tumordiagnostik und Tumortherapie von Plattenepithelkarzinomen New probe for early detection of epithelial dysplasia of the stratified squamous epithelium as well as for tumor diagnosis and tumor therapy of squamous cell carcinoma
08/14/1997CA2733866A1 Human cancer antigen of tyrosinase-related protein 1 and 2 and genes encoding same
08/14/1997CA2245783A1 Fhit proteins and nucleic acids and methods based thereon
08/14/1997CA2245508A1 Variants of thymidine kinase, related nucleic acids sequences and their use in genic therapy
08/14/1997CA2245170A1 Methods and compositions for transforming dendritic cells and activating t cells
08/14/1997CA2244812A1 Vectors and methods for providing cells with additional nucleic acid material integrated in the genome of said cells
08/14/1997CA2244110A1 Novel methods of vaccination and vaccines thereof comprising a nucleic acid encoding a first epitope and a peptide containing a second epitope
08/14/1997CA2243718A1 Diabetes therapy
08/13/1997EP0789077A1 Viral material and nucleotide fragments associated with multiple sclerose having diagnostic, prophylactic and therapeutical uses
08/13/1997EP0789076A2 G protein coupled receptor proteins, their production and use
08/13/1997EP0788543A1 Alk-7 (activin like kinase), a serine threonine kinase receptor
08/13/1997EP0788540A1 Human abh
08/13/1997EP0788374A2 Cell-specific gene delivery vehicles
08/13/1997EP0788367A1 Stretch-activated cation channel and antisense oligonucleotides thereto
08/13/1997EP0788366A1 Use of 2'-substituted oligonucleotides to down-regulating gene expression
08/13/1997EP0788364A1 Treatment of urogenital cancer with boron neutron capture therapy
08/13/1997EP0788307A1 Oligonucleotide modulation of multidrug resistance-associated protein
08/13/1997CN1156966A Polynucleotide vaccine for papillomavirus
08/13/1997CA2197408A1 Mutant human growth hormones and their uses
08/13/1997CA2197286A1 Nucleic acid constructs for the cell cycle-regulated expression of genes, cells containing such constructs and their use for preparing drugs
08/13/1997CA2197265A1 Target cell-specific vectors for inserting genes into cells, pharmaceuticals comprising such vectors and their use
08/12/1997US5656612 Antisense oligonucleotide modulation of raf gene expression
08/12/1997US5656611 Modified polynucleotide and copolymer having polyether segments and polycation segments; stabilizing polynucleic acids and increasing ability to cross cell membranes
08/12/1997US5656610 Injection into tongue muscle
08/12/1997US5656609 Method of enhancing and/or prolonging expression of gene introduced into a cell using colchicine
08/12/1997US5656481 Compositions and methods for the delivery of biologically active molecules using cells contained in biocompatible capsules
08/12/1997US5656465 Methods of in vivo gene delivery
08/12/1997US5656267 Implantable cells that alleviate chronic pain in humans
08/07/1997WO1997028269A1 Transduced human hematopoietic stem cells
08/07/1997WO1997028266A1 Human dnase resistant to actin inhibition
08/07/1997WO1997028265A1 Measles immunization by dna transcription unit inoculation
08/07/1997WO1997028259A1 Gene expression vectors which generate an antigen specific immune response and methods of using the same
08/07/1997WO1997028258A1 Cells expressing both human cd4 and cxcr4
08/07/1997WO1997028251A1 Combined radiotherapy and immunotherapy to treat cancer
08/07/1997WO1997028191A1 Mhc complexes and uses thereof
08/07/1997WO1997028186A1 PURIFIED SR-p70 PROTEIN
08/07/1997WO1997028178A1 High affinity nucleic acid ligands of complement system proteins
08/07/1997WO1997028175A1 Thyroid sodium/iodide symporter and nucleic acid encoding same
08/07/1997WO1997027876A1 Immunotherapy sensitization of cancer therapy
08/07/1997WO1997027871A1 Method of inactivation of ras subfamily proteins and agents therefor
08/07/1997WO1997021811A3 Novel tyrosine kinase receptors and ligands
08/07/1997WO1997012985A3 Multi-functional hematopoietic receptor agonists
08/07/1997DE19603668A1 Increasing immune response to tumour cells by increasing expression of TAP or LMP proteins
08/07/1997CA2630098A1 High affinity nucleic acid ligands of complement system proteins
08/07/1997CA2244841A1 Combined radiotherapy and immunotherapy to treat cancer
08/07/1997CA2244755A1 Mhc complexes and uses thereof
08/07/1997CA2196964A1 G protein coupled receptor proteins, their production and use
08/06/1997EP0787799A1 Staphylococcus aureus WCUH29 SpoIIIE Protein
08/06/1997EP0787797A1 Human 5-HT1D receptor (serotonin receptor), process for preparing the same, its uses, antibodies directed against this receptor and transgenics expressing it
08/06/1997EP0787206A1 USE OF NEURITE LOCALIZED mRNAs FOR MEDICAL DIAGNOSIS AND THERAPEUTICS
08/06/1997EP0787201A1 Poly(organo)phosphazenes for use in synthetic transfection systems
08/06/1997EP0787200A2 Improved adenovirus and methods of use thereof
08/06/1997EP0787199A1 Viable contaminant particle free adenoviruses, their preparation and use
08/06/1997EP0787198A1 Defective adenoviruses including a therapeutic gene and an immunoprotective gene
08/06/1997EP0787197A1 Immortalized lines of endothelial brain cells and therapeutical applications thereof
08/06/1997EP0787190A2 Hepatitis e virus antigens and uses therefor
08/06/1997EP0787182A2 Embryonal cardiac muscle cells, their preparation and their use
08/06/1997EP0787145A1 Novel tnf receptor death domain ligand proteins and inhibitors of ligand binding
08/06/1997EP0787142A1 Neurturin and related growth factors
08/06/1997EP0787016A1 Secretory leukocyte protease inhibitor as an inhibitor of tryptase
08/06/1997EP0787012A1 Suppression of proteolytic activity by dysfunctional protease formation
08/06/1997EP0786989A1 Lipid vesicles containing adeno-associated virus rep protein for transgene integration and gene therapy
08/06/1997EP0585368B1 Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products
08/05/1997US5654415 Antisense oligonucleotides to p53
08/05/1997US5654185 Methods, compositions and apparatus for cell transfection
08/05/1997US5654182 Site-specific integration or disassembly of nucleic acid sequences within the genome of a mammilian host cell for the activation or inactivation of a functional expression unit; lineage analysis of tissues
08/05/1997US5654155 Diagnosis of breast or ovanian cancer
08/05/1997US5654007 Friable, spherically aggregated particles of powdered drug; free-flowing, respiratory inhalants
08/05/1997US5653975 Implanting encapsulated cells capable of producing human growth factor or trophic factor for diffusion into the central nervous system; treatment of diabetes; anemia; hypoparathyroidism; parkinson's and alzheimer's disease
08/05/1997CA1339205C Oligonucleotide-polyamide conjugates
07/1997
07/31/1997WO1997027310A1 Retroviral vector and its use in gene therapy
07/31/1997WO1997027301A1 Decorin binding protein compositions and methods of use
07/31/1997WO1997027300A1 TOXOPLASMA GONDII ANTIGEN Tg20
07/31/1997WO1997027297A1 Inhibitors of cell-cycle progression, and uses related thereto
07/31/1997WO1997027296A1 Nucleic acids and proteins related to alzheimer's disease, and uses therefor
07/31/1997WO1997027286A1 Methods for using the obese gene and its gene product to stimulate hematopoietic development
07/31/1997WO1997027284A2 Human rad50 and septin-2 genes and methods of use
07/31/1997WO1997027216A1 Amplification of response from expressed recombinant protein
07/31/1997WO1997027208A1 Unique associated kaposi's sarcoma virus sequences and uses thereof
07/31/1997WO1997027206A1 Oligonucleotide analogs
07/31/1997WO1997026910A2 Tumour vaccine for immunotherapy of malignant tumours
07/31/1997WO1997026903A1 Microencapsulated genetically engineered microorganisms for clinical application
07/31/1997WO1997026853A2 Dna encoding galanin galr2 receptors and uses thereof
07/31/1997WO1997026790A1 APOPTOSIS INDUCED BY SHIGELLA IpaB
07/31/1997DE19602985A1 Tumour vaccine for treatment of, e.g., carcinoma melanoma or leukaemia
07/31/1997DE19602863A1 Agent for treating cancer and other diseases involving hyper-proliferation of cells