Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
11/1997
11/13/1997CA2253328A1 Polycistronic expression plasmid for tumor-rejection
11/13/1997CA2253322A1 Gene expression in monocytes and macrophages
11/13/1997CA2252845A1 Chimeric kanamycin resistance gene
11/13/1997CA2252470A1 Treatment of human cancers with an adenovirus vector containing an interferon consensus gene
11/12/1997EP0806484A2 Nucleotide sequences derived from the genomes of the retroviruses HIV-1, HIV-2 and SIV, and their application to the amplification of these viral genomes and to the in vitro diagnosis of infections resulting from these viruses
11/12/1997EP0805862A1 Borna disease viral sequences, diagnostics and therapeutics for nervous system diseases
11/12/1997EP0805859A1 A chemokine receptor able to bind to mcp-1, mip-1 alpha and/or rantes. its uses
11/12/1997EP0805858A2 Inhibition of neovascularization using vegf-specific oligonucleotides
11/12/1997EP0805678A1 Surface-modified nanoparticles and method of making and using same
11/11/1997US5686599 One-pot deprotection of rna comprising contacting base with anhydrous methyl amine, cooling, contacting with triethylamine-hydrogen fluoride
11/11/1997US5686597 Thrombin receptor homolog
11/11/1997US5686562 Diagnosis and treatment of cancer
11/11/1997US5686289 Seeding hollow fibers with renal tubule cells, culturing in presence of retinoic acid and epidermal growth factor, cell differentiation
11/11/1997US5686279 Method for production of high titer virus and high efficiency retroviral mediated transduction of mammalian cells
11/11/1997US5686278 Methods for enhanced retrovirus-mediated gene transfer
11/11/1997US5686264 Compositions and methods relating to transdominant Tat mutants
11/11/1997US5686245 Methods for screening for agents which modulate telomere length
11/06/1997WO1997041263A1 Detection of the leptin receptor in reproductive organs and methods for regulating reproductive biology
11/06/1997WO1997041245A1 Generation of viral transfectants using recombinant dna-derived nucleocapsid proteins
11/06/1997WO1997041243A2 A cytoplasmic gene expression system which utilizes a prokaryotic rna polymerase autogene
11/06/1997WO1997041241A1 Polycistronic expression constructs, their use and vaccines
11/06/1997WO1997041231A1 Processed polypeptides with il-16 activity, process for preparing the same and their use
11/06/1997WO1997041226A2 Polynucleotides encoding the transcriptional repressor gcf2 of the epidermal growth factor receptor
11/06/1997WO1997041222A1 HUMAN P2x4 RECEPTOR SPLICE-VARIANTS
11/06/1997WO1997041210A1 Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with rna
11/06/1997WO1997041156A1 Novel compounds
11/06/1997WO1997041151A2 Choline binding proteins for anti-pneumococcal vaccines
11/06/1997WO1997041150A2 Gene therapy for mitochondrial dna deffects using peptide nucleic acids
11/06/1997WO1997041147A1 Novel compounds
11/06/1997WO1997041146A1 Novel compounds
11/06/1997WO1997041141A1 Methods and compounds for curing diseases caused by mutations
11/06/1997WO1997040857A1 Drug delivery using terminal complement components
11/06/1997WO1997040855A1 Mammalian regulator of nonsense-mediated rna decay
11/06/1997WO1997040851A1 Novel compounds
11/06/1997WO1997040847A1 Therapeutic and drug screening methods for the treatment and prevention of neuronal disease
11/06/1997WO1997040839A1 Dna vaccine formulations
11/06/1997WO1997040679A1 Methods for delivering compounds into a cell
11/06/1997WO1997033608A3 Antagonism of endothelin actions
11/06/1997WO1997027284A3 Human rad50 and septin-2 genes and methods of use
11/06/1997CA2253595A1 Generation of viral transfectants using recombinant dna-derived nucleocapsid proteins
11/06/1997CA2253433A1 Mammalian regulator of nonsense-mediated rna decay
11/06/1997CA2253259A1 Processed polypeptides with il-16 activity, process for preparing the same and their use
11/06/1997CA2253252A1 Choline binding proteins for anti-pneumococcal vaccines
11/06/1997CA2252762A1 Methods and compounds for curing diseases caused by mutations
11/06/1997CA2252617A1 Methods for delivering compounds into a cell
11/06/1997CA2250759A1 A cytoplasmic gene expression system which utilizes a prokaryotic rna polymerase autogene
11/06/1997CA2230866A1 Human p2x4 receptor splice-variants
11/05/1997EP0805207A1 Polycistronic expression plasmid for tumor rejection
11/05/1997EP0804613A1 Tumor suppressor genes, proteins encoded thereby and use of said genes and proteins
11/05/1997EP0804602A1 Hsv viral vector
11/05/1997EP0804601A1 Genetic therapy of tumours with an endothelium cell-specific active substance which is dependent on the cell cycle
11/05/1997EP0804598A1 Recombinant rna viral vector and method of preparing the same
11/05/1997EP0804591A1 Serum paraoxonase
11/05/1997EP0804585A1 Capl-specific oligonucleotides and methods of inhibiting metastatic cancer
11/05/1997EP0804578A1 Il-2r-associated polypeptide and dna molecules coding therefor
11/05/1997EP0804577A2 cDNA ENCODING A BMP TYPE II RECEPTOR
11/05/1997EP0804574A1 Human kappa opioid receptor, nucleic acids and uses thereof
11/05/1997EP0804568A2 Multimeric forms of members of the steroid/thyroid superfamily of receptors with the ultraspiracle receptor
11/05/1997EP0804565A1 Tetracycline-regulated transcriptional modulators
11/05/1997EP0804562A1 Connective tissue growth factor-2
11/05/1997EP0804547A1 Unique associated kaposi's sarcoma virus sequences and uses thereof
11/05/1997EP0804456A1 Peptide nucleic acid conjugates
11/05/1997EP0804453A1 Method for detection and treatment of breast cancer
11/05/1997EP0804452A1 Recombinant c140 receptor and its agonists and antagonists
11/05/1997EP0804413A1 Nitrogen mustard prodrugs with novel lipophilic protecting groups, and processes for their production
11/05/1997EP0804249A2 Polymeric gene delivery system
11/05/1997EP0804226A1 Human choline acetyltransferase
11/05/1997EP0804222A1 Accessory factor function for interferon gamma and its receptor
11/05/1997EP0804218A1 Product and process for regulating signal transduction pathways
11/05/1997EP0804214A1 Growth differentiation factor-6
11/05/1997EP0804210A1 Method of immunomodulation by means of adoptive transfer of antigen-specific cytotoxic t-cells
11/05/1997EP0804076A1 Gene therapy involving concurrent and repeated administration of adenoviruses and immunosuppressive agents
11/05/1997EP0635068B1 Amplification of human mdm2 gene in human tumors
11/04/1997US5684147 Therapeutic anti-HIV anti-viral oligonucleotides and pharmaceutical formulations thereof
11/04/1997US5683987 Multidrug resistance phenotypes and nucleotide sequences
11/04/1997US5683986 Parenterally administering mismatched double stranded rna to a patient suffering from a herpes virus infection
11/04/1997US5683910 Human phosphorylase kinase gamma subunit
11/04/1997US5683902 Human papilloma virus inhibition by a hairpin ribozyme
11/04/1997US5683873 EGS-mediated inactivation of target RNA
10/1997
10/30/1997WO1997040183A2 Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
10/30/1997WO1997040182A1 Genetically transfected human dendritic cells, their production and use, preferably as vaccines
10/30/1997WO1997040180A1 Chicken embryo lethal orphan (celo) virus
10/30/1997WO1997040173A2 Pi 3-kinase fusion mutants and uses thereof
10/30/1997WO1997040164A1 Hepatitis b monoclonal antibodies
10/30/1997WO1997040163A1 Nucleic acid vaccination for parvoviral infections
10/30/1997WO1997040157A1 Matrix metalloprotease
10/30/1997WO1997040151A2 Secreted proteins and polynucleotides encoding them
10/30/1997WO1997040145A1 Inactivation resistant factor viii
10/30/1997WO1997040143A1 Apoptosis inducing protein and gene encoding the same
10/30/1997WO1997040072A2 Adam proteins and uses thereof
10/30/1997WO1997040069A2 Secreted proteins and polynucleotides encoding them
10/30/1997WO1997039776A1 Gene therapy involving concurrent and repeated administration of adenoviruses and immunosuppressive agents
10/30/1997WO1997039721A2 Methods and compositions for regulating t cell subsets by modulating transcription factor activity
10/30/1997WO1997039629A1 Viral vectors including polynucleotides encoding neurotrophic factors and uses therefor
10/30/1997WO1997035997A3 Recombinant pox virus encoding myelin protein for therapy
10/30/1997WO1997035993A3 PSA positive regulating (PSAR) sequences and uses thereof
10/30/1997WO1997025426A3 Compositions and methods for the treatment and diagnosis of breast cancer
10/30/1997WO1997006255A3 Mammalian apoptosis inhibitor protein gene family, primers, probes and detection methods
10/30/1997CA2429726A1 Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
10/30/1997CA2252835A1 Chicken embryo lethal orphan (celo) virus