Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
09/1997
09/03/1997EP0792283A1 SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH
09/03/1997EP0792278A1 Tumor necrosis factor-gamma
09/03/1997EP0792169A1 Tissue-specific treatment, diagnostic methods, and compositions using replication-deficient vectors
09/03/1997EP0792168A1 Novel tumor suppressor gene, hic-1
09/03/1997EP0792166A1 Internalisation of dna, using conjugates of poly-l-lysine and an integrin receptor ligand
09/03/1997EP0792156A1 Methods for the prevention or treatment of vascular hemorrhaging and alzheimer's disease
09/03/1997CN1158619A Delivery of nucleic acids
09/03/1997CN1158617A RNA component of telomerase
09/02/1997US5663071 An isolated polynucleotide
09/02/1997US5663070 Recombinant production of a soluble splice variant of the Fas (Apo-1) antigen, fas TM
09/02/1997US5663059 Polynucleotide with code, gene expression
09/02/1997US5662904 Anti-scarring compositions comprising growth factor neutralizing antibodies
09/02/1997US5662896 Directly administering a vector construct which directs the expression of antitumor agents
08/1997
08/28/1997WO1997031119A1 Methods and compositions for protective and therapeutic genetic immunization
08/28/1997WO1997031115A2 Synthetic hiv genes
08/28/1997WO1997031114A2 Polynucleotides and aminoacid sequences from staphylococcus aureus
08/28/1997WO1997031111A2 A family of organic anion transporters, nucleic acids encoding them, cells comprising them and methods for using them
08/28/1997WO1997031108A1 Modified nuclear glucocorticoid receptor, fusion protein, and dna fragments coding for said receptor and said fusion protein
08/28/1997WO1997030732A1 Liposomal-viral dna complexes for treating disease
08/28/1997WO1997030731A2 Method of preparing polynucleotide-carrier complexes for delivery to cells
08/28/1997WO1997030722A1 Use of glial neurotrophic factor (gdnf) for treatment of hearing disorders
08/28/1997WO1997030721A1 Pharmaceutical composition for immunomodulation based on peptides and adjuvants
08/28/1997WO1997030587A1 Dna vaccination for induction of suppressive t cell response
08/28/1997WO1997026523A3 Detection of a leptin receptor variant and methods for regulating obesity
08/28/1997WO1997020935A3 Viral vectors
08/28/1997WO1997020051A3 Vectors and methods for gene transfer to cells
08/28/1997WO1997019180A3 Vector consisting of a transcriptional regulatory DNA sequence linked to a DNA sequence encoding beta-lactamase for enzyme prodrug therapy
08/28/1997WO1997016535A3 Methods for use of mpl ligands with primitive human stem cells
08/28/1997CA2247517A1 Modified nuclear glucocorticoid receptor, fusion protein, and dna fragments coding for said receptor and said fusion protein
08/28/1997CA2246359A1 Methods and compositions for protective and therapeutic genetic immunization
08/28/1997CA2245646A1 Synthetic hiv genes
08/28/1997CA2241142A1 Liposomal-viral dna complexes for treating disease
08/27/1997EP0791654A1 Polypeptides corresponding to the amino acid sequences of proteins p57 or p9.5 of Borna disease virus, nucleic acid fragments coding therefore and their use for diagnostic and immunization purposes
08/27/1997EP0791065A1 Protein targeting into hiv virions based on hiv-1 vpr fusion molecules
08/27/1997EP0791064A1 Method for enhancing the immunogenicity of an immunogenic compound or hapten, and use thereof for preparing vaccines
08/27/1997EP0791061A1 Animals with targeted gene disruption
08/27/1997EP0791060A2 Ribozyme analogs
08/27/1997EP0791059A1 Production of recombinant peptides as natural hydrophobic peptide analogues
08/27/1997EP0791050A1 Vectors for tissue-specific replication
08/27/1997EP0791010A1 Retroviral vectors containing recombinant cmv-ie/hiv-tar/moloney murine leukemia virus long terminal repeats
08/27/1997EP0637966B1 Bystander effect tumoricidal therapy
08/27/1997CN1158144A Genetic therapy of vascular diseases with a cell-specific active substance which is dependent on the cell cycle
08/26/1997US5661132 Delivery to wound a dna-coated gold bead genetic construct which encodes epidermal growth factor
08/26/1997US5661126 Use of mullerian inhibiting substance for treating certain tumors and for modulating class I major histocompatibility antigen expression
08/26/1997US5661032 Controller of transcription of marker gene
08/26/1997US5661025 Self-assembling polynucleotide delivery system comprising dendrimer polycations
08/26/1997US5660825 Treating autoimmune disorders by administering protein complex deactivator
08/21/1997WO1997030178A2 Diagnosing trinucleotide repeat diseases and genes involved therein
08/21/1997WO1997030167A1 Method of treating liver disorders
08/21/1997WO1997030157A1 Novel human myeloid terminal differentiation response gene
08/21/1997WO1997030155A1 Gene therapy method using fgf-5
08/21/1997WO1997030153A1 Probe for the early detection of displasias in multilayer tesselated epithelium and for the diagnosis and therapy of carcinomas
08/21/1997WO1997030149A1 Novel era
08/21/1997WO1997030108A1 Characterized brca1 and brca2 proteins and screening and therapeutic methods based on characterized brca1 and brca2 proteins
08/21/1997WO1997030083A1 Gene therapy of entothelial cells with anti-apoptotic proteins for transplantation and inflammatory conditions
08/21/1997WO1997030070A1 Novel compounds
08/21/1997WO1997030066A1 NOVEL PENILE NEURONAL NITRIC OXIDE SYNTHASE (PnNOS) AND APPLICATIONS FOR DIAGNOSIS AND TREATMENT OF UROGENITAL DISORDERS
08/21/1997WO1997030065A1 Compositions and methods for the treatment and diagnosis of cardiovascular disease
08/21/1997WO1997030058A1 Phosphatidyl oligoglycerols
08/21/1997WO1997029781A1 Methods and compositions for modulating an immune response
08/21/1997WO1997029780A1 Methoxyethoxy oligonucleotides for modulation of protein kinase c expression
08/21/1997WO1997029757A1 Rnase l activators and antisense oligonucleotides effective to treat rsv infections
08/21/1997WO1997023613A3 Cell activation process and reagents therefor
08/21/1997WO1997017369A3 Dna comprising a neuron-specific transcriptional promoter and its use in a gene therapy vector
08/21/1997WO1997014806A3 Delivery of biologically active polypeptides
08/21/1997DE19622224A1 Phosphatidyloligoglycerine Phosphatidyloligoglycerols
08/21/1997CA2247246A1 Compositions and methods for the treatment and diagnosis of cardiovascular disease
08/21/1997CA2246578A1 Novel human myeloid terminal differentiation response gene
08/21/1997CA2246503A1 Rnase l activators and antisense oligonucleotides effective to treat rsv infections
08/21/1997CA2246362A1 Diagnosing trinucleotide repeat diseases and genes involved therein
08/21/1997CA2246230A1 Methoxyethoxy oligonucleotides for modulation of protein kinase c expression
08/21/1997CA2245503A1 Gene therapy of entothelial cells with anti-apoptotic proteins for transplantation and inflammatory conditions
08/21/1997CA2197847A1 Polypeptides corresponding to the amino acid sequences of proteins p57 or p9.5 of borna disease virus, nucleic acid fragments coding therefor and their use for diagnostic and immunization purposes
08/20/1997EP0790313A2 Nucleic acid constructs for the cell cycle regulated expression of genes, cells comprising said constructs and their use for the preparation of medical compositions
08/20/1997EP0790312A2 Target cell specific vectors for the insertion of genes into cells, medicament containing such vectors and their use
08/20/1997EP0790305A1 Mutant human growth hormones and their uses
08/20/1997EP0789776A1 Nucleic acid transfer system
08/20/1997EP0789764A1 A novel family of protease inhibitors, and other biologic active substances
08/20/1997EP0789762A1 Methods for the diagnosis of glaucoma
08/20/1997EP0789757A1 Transgenic organisms and their uses
08/20/1997EP0789708A1 Multifunctional molecular complexes for gene transfer to cells
08/20/1997EP0789706A1 Sugar modified nucleosides and their use for synthesis of oligonucleotides
08/20/1997EP0789593A1 Yeast-based delivery vehicles
08/20/1997EP0789592A1 Ocular gene therapy
08/20/1997EP0789591A1 Methods for identifying individuals suffering from a cellular abnormality
08/20/1997EP0789575A1 Peripheral nervous system specific sodium channels, dna encoding therefor, crystallization, x-ray diffraction, computer molecular modeling, rational drug design, drug screening, and methods of making and using thereof
08/20/1997EP0789574A1 Methods and devices for immunizing a host to tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides
08/20/1997EP0789564A1 Polynucleotide compositions
08/20/1997EP0789563A1 Hepatitis virus vaccines
08/20/1997EP0452457B1 Method of in vivo delivery of functioning foreign genes
08/19/1997US5658892 Compound delivery using high-pressure impulse transients
08/19/1997US5658891 Oligonucleotide therapies for modulating the effects of herpesviruses
08/19/1997US5658786 DNA encoding rat taurine transporter and uses thereof
08/19/1997US5658785 Adeno-associated virus materials and methods
08/19/1997US5658780 Rel a targeted ribozymes
08/19/1997US5658776 Generation of high titers of recombinant AAV vectors
08/19/1997US5658774 Inhibiting growth of tumor cells expressing oncogenes by introducing in vitro dna sequence encoding interferon regulatory factor, expressing said sequence
08/19/1997US5658729 Method, reagent and kit for evaluating susceptibility to premature atherosclerosis
08/19/1997US5658568 Cytotoxic drug therapy
08/19/1997US5658567 Recombinant glycosylated biologically active human alpha-galactosidase a obtained by culturing host cell comprising recombinant baculovirus comprising nucleic acid encoding said enzyme, recovering