Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
02/2003
02/13/2003WO2003011898A2 Synthetic or natural peptides binding protein phosphatase 2a, identification method and uses
02/13/2003WO2003011887A2 Antisense modulation of apolipoprotein b expression
02/13/2003WO2003011343A1 Method of regenerating bone/chondral tissues by transferring transcriptional factor gene
02/13/2003WO2003011334A1 Vaccine comprising gp120 and nef and/or tat for the immunisation against hiv
02/13/2003WO2003011326A1 Use of long pentraxin ptx3 for treating female infertility
02/13/2003WO2003011304A1 Modulation of insulin-regulated aminopeptidase (irap)/angiotensin iv (at4) receptor activity
02/13/2003WO2003011252A1 Pharmaceutical composition comprising lipids comprising a polar and a nonpolar moiety
02/13/2003WO2003011008A2 Therapeutic delivery compositions and methods of use thereof
02/13/2003WO2002088352A3 Schwann cell specific enhancer and methods of use thereof
02/13/2003WO2002080849A3 Chemotherapeutic induction of egr-1 promoter activity
02/13/2003WO2002059261A3 Inhibition of restenosis using a dna-coated stent
02/13/2003WO2002055556A3 Regulation of human voltage gated potassium channel protein kv2.2
02/13/2003WO2002032958A3 Polynucleotide and polypeptide sequences of human dendritic cell immunoreceptors
02/13/2003WO2002020747A3 Regulation of human tyrosine phosphatase-like enzyme
02/13/2003WO2002000862A8 32447, a novel human acyltransferase and uses thereof
02/13/2003WO2001092567A3 Novel target genes for diseases of the heart
02/13/2003WO2001087286A3 Antisense enzyme inhibitors for improving pharmacokinetics of a drug
02/13/2003WO2001083796A3 Adenoviral vectors for tumor specific gene expression and uses thereof
02/13/2003US20030033617 Generation of nuclear transfer embryo; obtain cells, remove nucleus from one, transfer to enucleated cell, transform with artifical chromosome, recover and monitor gene expresion in the cell
02/13/2003US20030032790 Mammal use as model in the diagnosis, prevention and treatment of hypercholesteremia or hyperlipoproteinemia, obesity, diabetes, tumors, anorexia, hyperlipidemia, lipoprotein defects, osteoporosis, arthritis and tumors
02/13/2003US20030032786 Polynucleotide encoding a novel human potassium channel beta-subunit, K+betaM2
02/13/2003US20030032775 Effector proteins of rapamycin
02/13/2003US20030032615 Lipid-mediated polynucleotide administration to deliver a biologically active peptide and to induce a cellular immune response
02/13/2003US20030032613 Novel adenovirus gene therapy vehicle and cell line
02/13/2003US20030032612 Inhibit expression of a gene in the operon; reducing bacterial resistance to antibiotics
02/13/2003US20030032610 Administering one or more oligonucleotides which share at least 50% nucleotide sequence identity with (TTAGGG)n or oligonucleotides which share at least 50% nucleotide sequence identity with the human telomere overhang repeat.
02/13/2003US20030032606 Methods of detecting and treating microsatellite-instability positive tumors using RIZ
02/13/2003US20030032597 Targeting nucleic acids to a cellular nucleus
02/13/2003US20030032596 Administering a compound that modulates the synthesis or expression of a target cellular gene, especially a Src kinase.
02/13/2003US20030032187 Selective antibody targeting of undifferentiated stem cells
02/13/2003US20030032181 Generation of radial glial cells for use in the treatment of nervous system disorders; obtain neuronal stem cells, incubate with modulator, propagate cells, recover glial cells
02/13/2003US20030032179 Post-partum mammalian placenta, its use and placental stem cells therefrom
02/13/2003US20030032166 Aortic carboxypeptidase-like protein and nucleic acids encoding same
02/13/2003US20030032144 Nucleic acid constructs useful for glucose regulated production of human insulin in somatic cell lines
02/13/2003US20030032142 Nucleotide sequences coding membrane protein for use in the treatment and prevention of infections
02/13/2003US20030032098 Bone morphogenic protein
02/13/2003US20030032097 DNA encoding human vanilloid receptor VR3
02/13/2003US20030032095 Novel nucleic acid sequences encoding human semaphorin-like polypeptides
02/13/2003US20030032075 Monoclonal or recombinant antibody for use in the treatment of tumors
02/13/2003US20030032073 Method for diagnosis and therapy of Hodgkin's lymphomas
02/13/2003US20030032030 Determination of age in animals; obtain tissue sample from animal, monitor expression pattern of marker gene, compare to expression pattern in younger control, evaluate sample for aging
02/13/2003US20030032027 Amplified cancer gene WIP1
02/13/2003US20030032009 09007761method for influencing the p53 linkage to target genes
02/13/2003US20030032005 Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents
02/13/2003US20030031704 Liposome composition for delivery of nucleic acid
02/13/2003US20030031696 Artificial salivary gland
02/13/2003US20030031683 Selecting for a strain of bacteria having an RpoS+ phenotype, inactivating mutations which render the strain attenutated, and a recombinant gene encoding the product
02/13/2003US20030031681 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
02/13/2003US20030031678 Compositions and methods relating to prostate specific genes and proteins
02/13/2003US20030031670 Diagnosis and treatment of malignant neoplasms
02/13/2003US20030031665 Anti-CD26 monoclonal antibodies as therapy for diseases associated with cells expressing CD26
02/13/2003US20030031662 Delivering pituitary tumor transforming gene carboxy-terminal peptide (PTTG-C) to mammalian cell such that the PTTG-C peptide is expressed in the cell, whereby neoplastic cellular proliferation and/or transformation of the cell is inhibited
02/13/2003US20030031660 Administering to the subject a therapeutically effective amount of heparanase for inducing bone formation
02/13/2003US20030031657 Stem cells and their use in transplantation
02/13/2003US20030031654 Prohormone convertase transformed cells and polypeptide synthesis
02/13/2003US20030031650 Drug inducible system and use thereof
02/13/2003US20030031649 Gene therapy to promote angiogenesis
02/13/2003US20030031645 Administering to an animal a biologically effective amount of a pharmaceutically acceptable CXC chemokine formulation that comprises an XXX-CXC chemokine other than PF4, the XXX-CXC chemokine lacking the amino acid sequence ELR (Glu Leu Arg)
02/13/2003CA2456003A1 Regulator of calcineurin
02/13/2003CA2455843A1 Therapeutic delivery compositions and methods of use thereof
02/13/2003CA2455647A1 Enhancing organ maturity in neonates and predicting their duration of intensive care
02/13/2003CA2455329A1 Vaccine comprising gp120 and nef and/or tat for the immunisation against hiv
02/13/2003CA2455228A1 Antisense modulation of apolipoprotein b expression
02/13/2003CA2455194A1 Vascular endothelial growth factor isoform having anti-angiogenic activity
02/13/2003CA2454421A1 Use of long pentraxin ptx3 for treating female infertility
02/13/2003CA2454147A1 Inhibitor of dna methylation
02/13/2003CA2453522A1 Antigen presenting cells, method for their preparation and their use for cancer vaccines
02/13/2003CA2453372A1 Methylation resistant vectors
02/13/2003CA2451868A1 Pharmaceutical composition comprising lipids comprising a polar and a nonpolar moiety
02/12/2003EP1283268A2 Recombinant vascular endothelial cell growth factor D (VEGF-D)
02/12/2003EP1283260A1 Novel insulin/igf/relaxin family polypeptides and dnas thereof
02/12/2003EP1283255A1 Myocardial cell proliferation-associated genes
02/12/2003EP1282712A2 Synthetic gagpol genes and their uses
02/12/2003EP1282705A2 Endothelial differentiation gene 6-like g protein coupled receptor
02/12/2003EP1282702A2 Immunogenic polypeptides encoded by mage minigenes and uses thereof
02/12/2003EP1282700A1 Neuronal serine-threonine protein kinase
02/12/2003EP1282699A2 Splice-region antisense composition and method
02/12/2003EP1282685A2 Pluripotent cells comprising allogenic nucleus and mitochondria
02/12/2003EP1282644A1 Tm4sf receptor polynucleotides, polypeptides, and antibodies
02/12/2003EP1282641A1 Human cervical cancer suppressor protein, polynucleotide encoding the protein, cell transformed with the polynucleotide and method for suppressing proliferation of cancer cell using the expression vector
02/12/2003EP1282639A2 Polyamide nucleic acid derivatives, agents and methods for producing the same
02/12/2003EP1282449A2 Treatment of human papillomavirus (hpv)-infected cells
02/12/2003EP1282436A2 Treatment of acute coronary syndrome with glp-1
02/12/2003EP1282427A2 Immunostimulatory polynucleotide sequences for use in suppressing hepatitis virus infection
02/12/2003EP1282403A1 Non-invasive gene targeting to the brain
02/12/2003EP0969877B1 Methods for the modulation of the growth of collateral arteries and/or other arteries from preexisting arteriolar connections
02/12/2003EP0694068B1 Genetic suppressor elements associated with sensitivity to chemotherapeutic drugs
02/12/2003CN1395969A Leptospiral DNA vaccine
02/11/2003US6519492 Method and apparatus for direct in vivo gene transfer by electrotransfection
02/11/2003US6518480 Selective target cell activation by expression of a G protein-coupled receptor activated superiorly by synthetic ligand
02/11/2003US6518413 Isolated nucleic acid encoding the polypeptide which, on expression in a host cell, produces the polypeptide; use in treatment of muscular dystrophy
02/11/2003US6518412 Gene therapy approaches to supply apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
02/11/2003US6518403 Antibodies that bind an adipocyte-specific protein homolog
02/11/2003US6518255 Administering, via multiple applications to target tissue, a dose of an adenoviral vector comprising a DNA encoding an angiogenic peptide which is an endothelial growth factor and a carrier to increase level of perfusion of blood to target
02/11/2003US6518066 Acylated Homoserine Lactone (AHL) compounds and AHL receptors derived from bacterial quorum sensing systems; inducible or repressible promotors regulate gene expression in plants and plant cells
02/11/2003US6518063 Osf2/Cbfa1 nucleic acids and methods of use therefor
02/11/2003US6518062 Enzyme combinations for destroying proliferative cells
02/11/2003US6518046 DNA (RNA) encoding such chemolcine polypeptides. Moreover, a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such Ck beta -9 polypeptides for the treatment of
02/11/2003US6518041 An isolated non-protein-encoding nucleic acid sequence functioning as a hormone response element which binds an androgen- or a progesterone- regulated receptor, comprising: a DNA sequence of the formula (SEQ ID NO:6) (N)x TCTCATTCTGTTCC,
02/11/2003US6518033 The present invention relates to a method of diagnosing, classifying and grading of tumor growths and to determine whether the use of chimeric polioviruses is a proper course for the treatment of the tumors. More particularly, the method