Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
03/2003
03/06/2003US20030045494 Synthetic oligonucleotides complementary to nucleic acids encoding epidermal growth factor
03/06/2003US20030045492 Comprising contacting skin of the animal with a vector that expresses a nucleic acid molecule encoding the gene product, in an amount effective to induce the response.
03/06/2003US20030045490 Therapeutic antisense phosphodiesterase inhibitors
03/06/2003US20030045489 Administering anti-angiogenic FGF-19 polypeptides or an anti-angiogenic FGF-19 nucleic acid to inhibit angiogenesis; antitumor agents
03/06/2003US20030045485 Reducing the viability of a proliferating mammalian cells such as cancer cells by increasing the level or activity of p53 in the cell.
03/06/2003US20030045462 Also vectors and host cells comprising those nucleic acid sequences, chimeric molecules of these polypeptides fused to heterologous polypeptide sequences, antibodies which bind to these polypeptides
03/06/2003US20030045459 67 Human secreted proteins
03/06/2003US20030045456 Complex comprising OCIF and polysaccharide
03/06/2003US20030044982 Expression vector coding blood coagulation protein for use in the treatment of blood disorders
03/06/2003US20030044981 Pseudotyped lentiviral vectors and uses thereof
03/06/2003US20030044961 Compositions for transferring active compounds in a cell-specific manner
03/06/2003US20030044957 Zinc finger proteins for DNA binding and gene regulation in plants
03/06/2003US20030044953 Novel telomerase
03/06/2003US20030044946 Genes, mutations, and drugs that increase cellular resistance to damage and extend longevity in organisms from yeast to humans
03/06/2003US20030044912 KCNQ potassium channels and methods of modulating same
03/06/2003US20030044898 Nucleotide sequences coding polypeptide for use in the treatment of asthma, parkinson's, heart defects, hypotension, urogenital and bone disorders
03/06/2003US20030044890 Nucleotide sequences coding polypeptide for use in the treatment of Alzheimer's disease and brain disorders
03/06/2003US20030044851 Secreted protein HCEJQ69
03/06/2003US20030044828 Progressive elevated gene-3 (PEG-3) induces aggressive cancer phenotype and regulates angiogenesis
03/06/2003US20030044813 Diagnosing cancer in humans; obtain tissue, incubate with marker agent, detect signal, evaluate for cancer
03/06/2003US20030044809 Detection of preferential transcription factor; obtain library, screen with probe, detect hybridization, recover clone, monitor transcriptional activity of protein codes in cloned nucleotide sequences
03/06/2003US20030044792 Methods and materials relataing to novel stem cell growth factor-like polypeptides and polynucleotides
03/06/2003US20030044773 Genetically engineering viral polypeptide; obtain nucleotide sequences coding polypeptide, insert codon, clone into vector, transform cell, detect expression of genetically engineered polypeptide
03/06/2003US20030044468 Shaping polymeric precursors by inducing thermal gelation of an aqueous solution thereof and then curing said precursors by crosslinking reactive groups; biomedical uses include drug delivery, microencapsulation, implantation
03/06/2003US20030044427 Compositions and methods for treating Papillomavirus-infected cells
03/06/2003US20030044419 Use of reagents derived from nucleic acid and amino acid sequences of Int6 gene in diagnostic methods, immunotherapy, gene therapy and as vaccines
03/06/2003US20030044408 Surface modification for improving biocompatibility
03/06/2003US20030044404 Regulation of angiogenesis with zinc finger proteins
03/06/2003US20030044392 Gene therapy; prevent transformation of cells
03/06/2003US20030044386 Genetic engineering; nucleic acid coding cytokines
03/06/2003US20030044385 Antitumor, anticancer agents
03/06/2003US20030044383 Tissue specific adenoviral vectors
03/06/2003US20030044352 Autoimmune disease, anticarcinogenic agents
03/06/2003CA2496180A1 Nucleic acid and polypeptide linked to breast cancer and uses therefor
03/06/2003CA2494870A1 Methods for inhibiting angiogenesis
03/06/2003CA2459697A1 Apparatus and method for electroporation of biological samples
03/06/2003CA2459183A1 Amplified oncogenes and their involvement in cancer
03/06/2003CA2458866A1 Compositions and methods of treating diabetes
03/06/2003CA2458849A1 Obesity related genes expressed at least in the hypothalamus, liver or pancreas
03/06/2003CA2458565A1 New angiogenesis inhibitors based on soluble cd44 receptor hyaluronic acid binding domain
03/06/2003CA2458506A1 Wild-type ras as a cancer therapeutic agent
03/06/2003CA2458443A1 Bioadhesive compositions and methods for enhanced mucosal drug absorption
03/06/2003CA2458394A1 Lipophilic drug compositions
03/06/2003CA2458381A1 Transmembrane protein differentially expressed in cancer
03/06/2003CA2458236A1 Gpi-anchored cytokines
03/06/2003CA2458226A1 Improved nitroreductase enzymes
03/06/2003CA2457903A1 Proaerolysin containing protease activation sequences and methods of use for treatment of prostate cancer
03/06/2003CA2457890A1 Vaccine using papillomavirus e proteins delivered by viral vector
03/06/2003CA2457879A1 Modulators of bone homeostasis identified in a high-throughput screen
03/06/2003CA2421442A1 Host cells for packing a recombinant adeno-associated virus (raav), method for the production and use thereof
03/05/2003EP1288304A2 Self-assembled, defective, non-self-propagating viral particles
03/05/2003EP1288299A2 TRNA synthetase
03/05/2003EP1288298A2 TRNA synthetase from Staphylococcus aureus
03/05/2003EP1288297A1 Regulation of mt1-mmp activity
03/05/2003EP1288227A1 Coactivator of nuclear receptors
03/05/2003EP1288222A1 Peptidic compounds selectively binding to P-selectin
03/05/2003EP1287830A1 Use of methioninase as an antitumor agent in anti-methionine chemotherapy
03/05/2003EP1287362A2 Compositions and methods for modulating tumor specific expression
03/05/2003EP1287355A2 Methods and compounds for influencing $g(b)3 integrin-dependent intracellular processes
03/05/2003EP1287161A2 Differentially expressed genes involved in angiogenesis, the polypeptides encoded thereby, and methods of using the same
03/05/2003EP1287153A2 Methods and compositions for efficient gene transfer using transcomplementary vectors
03/05/2003EP1287142A1 Nucleic acid molecule comprising a nucleic acid sequence coding for an sdf-1 gamma chemokine, a neuropeptide precursor or at least one neuropeptide
03/05/2003EP1287130A2 Mammalian cytokine receptor subunit proteins, related reagents and methods
03/05/2003EP1287121A2 Extracellular domain of ryk protein for regulating angiogenesis
03/05/2003EP1287031A2 Polynucleotides encoding for polymorphic isoforms of the pthrp protein, the encoded proteins and their therapeutic applications thereof
03/05/2003EP1287028A2 Compositions and methods for the therapy and diagnosis of colon cancer
03/05/2003EP1287027A2 Control of tgf(beta) signaling by km23 superfamily members
03/05/2003EP1287025A1 Sheep lice, bovicola ovis, allergen treatment
03/05/2003EP1287023A1 Methods and means for enhancing skin transplantation using gene delivery vehicles having tropism for primary fibroblasts, as well as other uses thereof
03/05/2003EP1287020A2 Cancer diagnosis and assays for screening anti-cancer agents
03/05/2003EP1287019A1 Therapeutic approaches to diseases by suppression of the nurr subfamily of nuclear transcription factors
03/05/2003EP1287015A1 Extracellular matrix polynucleotides, polypeptides, and antibodies
03/05/2003EP1287013A2 Nucleic acids containing single nucleotide polymorphisms and methods of use thereof
03/05/2003EP1286703A2 Methods and compounds for controlled release of recombinant parvovirus vectors
03/05/2003EP1286701A2 Gene directed enzyme prodrug therapy (gdept) for cell ablation
03/05/2003EP1286693A1 Complexes of alpha (2) macroglobulin and antigenic molecules for immunotherapy
03/05/2003EP1286684A2 Cxcr4 antagonist treatment of hematopoietic cells
03/05/2003EP1286678A2 Combination of a mutant herpes virus and a chemotherapeutic agent for the treatment of cancer
03/05/2003EP0971692B1 Specific magnetosome, method for the production and use thereof
03/05/2003EP0845034B1 peptide having pronociceptive properties
03/05/2003EP0554352B1 A method for transplanting cells into the brain and therapeutic uses therefor
03/05/2003CN1400907A 9M-negative EHV-mutants
03/05/2003CN1400020A heterogenic chimaera, its preparation method and application
03/05/2003CN1400019A Transgene clone cancer-resisting and cancer-curing technology
03/04/2003WO2002020614A2 Endoglin-specific polypeptide, production and use thereof
03/04/2003US6528637 Fatty acid synthase mRNA binding protein
03/04/2003US6528635 Tumor antigen protein, gene thereof, and utilization thereof
03/04/2003US6528634 Aiolos gene
03/04/2003US6528633 Cyclin-selective ubiquitin carrier polypeptides
03/04/2003US6528493 Modulating activity of endogenous protein
03/04/2003US6528479 Dominant negative mutants of IRS-1 and uses thereof
03/04/2003US6528315 Transfection of preferential nucleotide sequences into aggregations; mix sample and nucleotide sequences, incubate, expose to electric pulse, recover transformed aggregations
03/04/2003US6528314 Procedure for specific replacement of a copy of a gene present in the recipient genome by the integration of a gene different from that where the integration is made
03/04/2003US6528313 Production of transgenic animals; targeted replacement of an endogenous gene; genetic trait expression
03/04/2003US6528312 Nuclease inhibitor (G-Actin) or interleukin-10 (IL-10) use improving cell transfection; mixtures; polynucleotides; use gene therapy, vaccines
03/04/2003US6528310 Cancer control
03/04/2003US6528306 Engraftable human neural stem cells
03/04/2003US6528294 To effect protein phosphorylation; for use in diagnosis and therapy
03/04/2003US6528263 Identifying a cell expressing protooncogene polypeptide by contacting a nucleic acid with a polynucleotide reagent and detecting its binding; can be used in diagnosis and treatment of cancer
03/04/2003US6528259 Methods for detecting human methylenetetrahydrofolate reductase allelic variants