Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
01/2003
01/02/2003US20030003447 Methods and compositions for modulating the interaction between the APJ receptor and the HIV virus
01/02/2003US20030003143 Lipidic microparticles linked to multiple proteins
01/02/2003US20030003114 Hexosaminidase covalently attached to a cancer cell targeting ligand; improves selectively of the hexosaminidase for tumor cells
01/02/2003US20030003112 Avipox virus containing foreign DNA from porcine reproductive and respiratory syndrome virus; immunological compositions containing the recombinant poxvirus for inducing an immunological response in a host animal
01/02/2003US20030003103 Sequences for targeting metastatic cells
01/02/2003US20030003100 Gene therapy strategy, comprising an antibody-nucleic acid-cationic macromolecule complex that enhances nucleic acid delivery to mammalian cells
01/02/2003US20030003092 Administering an immunotherapeautic agent in conjunction with a tumour growth restricting agent, in amounts effective to eradicate any advanced or large tumours present
01/02/2003US20030003088 A human pancreatic ductal cell line immortalized with human papilloma virus genes E6 and E7 and which is capable of produce insulin; treating insulin-dependent diabetes; determining a chemical agent to induce cell differentiation
01/02/2003US20030003087 Use of marrow-derived glial progenitor cells as gene delivery vehicles into the central nervous system
01/02/2003US20030003086 A genetic engineered cell comprising an exogenously derived nucleic acid coding for a thimet oligopeptidase (TOP) polypeptide; modulate antigen presentation on cell surfaces, works synergistically with immunosuppressive drugs
01/02/2003US20030003085 Drug delivery of a muscle protein by administering purified donor muscle side population cells; gene therapy, in the treatment muscle diseases muscular dystrophies, genetic diseases, treating cancer, and bone marrow transplant
01/02/2003US20030003079 Recombinant pox virus for immunization against tumor-associated antigens
01/02/2003US20030003077 A genetic engineered adenoviral vector contains an adenoviral genome from which the open reading frames E1 and/or E3 were deleted and a therapeutic gene or a DNA sequence that encodes for therapeutic proteins useful in fibrosis treatment
01/02/2003US20030003076 Adenovirus E1B-55K single amino acid mutants and methods of use
01/02/2003EP1271153A2 Collapsin response mediator protein-1 as tumor metastasis marker
01/02/2003EP1271146A1 Method and composition of cellular reprogramming
01/02/2003EP1270732A1 Improved transfection of eukaryontic cells with linear polynucleotides by electroporation
01/02/2003EP1270719A2 Cell population containing non-fetal hemangioblasts and method for producing same
01/02/2003EP1270586A2 Composition for the cell-specific transfer of active substances
01/02/2003EP1270044A2 Wound healing biomarkers
01/02/2003EP1270016A1 Aids virus vaccine with the use of sendai virus vector
01/02/2003EP1270015A2 A complex comprising OCIF and Polysaccharide
01/02/2003EP1270000A2 Benzoic acid substituted benzopyrans for the treatment of atherosclerosis
01/02/2003EP1268861A2 Diagnosis of diseases associated with dna transcription
01/02/2003EP1268857A2 Diagnosis of diseases associated with gene regulation
01/02/2003EP1268855A2 Diagnosis of diseases associated with tumor suppressor genes and oncogenes
01/02/2003EP1268854A1 High specificity marker detection
01/02/2003EP1268835A1 Retinoic acid receptor beta-2, its antagonists, and gene therapy vectors for the treatment of neurological disorders
01/02/2003EP1268833A2 Modified nodavirus rna for gene delivery
01/02/2003EP1268817A1 Human pyruvate dehydrogenese phosphatase
01/02/2003EP1268812A2 Vectors for gene therapy
01/02/2003EP1268806A1 Clostridium difficile polypeptides and uses thereof
01/02/2003EP1268802A2 Beta-like glycoprotein hormone polypeptide and heterodimer
01/02/2003EP1268799A2 Antagonist antibodies to ve-cadherin without adverse effects on vascular permeability
01/02/2003EP1268798A2 Anti-angiogenic and anti-tumor properties of vascostatin and other nidogen domains
01/02/2003EP1268795A2 Regulation of human mas oncogene-related g protein-coupled receptor
01/02/2003EP1268792A2 Wnt-7b-like polypeptides and nucleic acids encoding same
01/02/2003EP1268791A2 Brca-1 regulators and methods of use
01/02/2003EP1268790A1 Gene coding for erbin, and diagnostic and therapeutic uses thereof
01/02/2003EP1268787A2 Human tap-like protein (transporter associated in antigen processing/presentation)
01/02/2003EP1268785A2 Gtp-binding protein gamma-12 subunit
01/02/2003EP1268784A2 Genes involved in intestinal inflammatory diseases and use thereof
01/02/2003EP1268783A2 Anti-angiogenic and anti-tumor properties of matin and other laminin domains
01/02/2003EP1268781A2 G12l, a gene associated with the thermal response
01/02/2003EP1268778A1 Materials and methods relating to a novel splice variant of a na + dependent glutamate transporter
01/02/2003EP1268775A1 The high bone mass gene of 11q13.3
01/02/2003EP1268774A2 Identification of essential genes in prokaryotes
01/02/2003EP1268773A1 Immune system-related polynucleotides, polypeptides, and antibodies
01/02/2003EP1268772A2 Peptide and nucleic acid coding therefor for the detection, diagnosis and therapy of diseases of the nervous system
01/02/2003EP1268771A1 Human gata-5 transcription factor
01/02/2003EP1268768A2 Targeted chromosomal genomic alterations with modified single stranded oligonucleotides
01/02/2003EP1268761A2 Human urothelial cell specific uroplakin transcriptional regulatory sequences, vectors comprising the same, and methods of use thereof
01/02/2003EP1268759A2 Genes of il-12p40 subunit mutated for improving the activity of il-12 and use thereof for dna vaccine adjuvant
01/02/2003EP1268555A2 Ligands directed to the non-secretory component, non-stalk region of pigr and methods of use thereof
01/02/2003EP1268548A2 Regulation of human rta-like g protein-coupled receptor
01/02/2003EP1268547A2 Methods of modulating drug clearance mechanisms by altering sxr activity
01/02/2003EP1268543A2 Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides
01/02/2003EP1268542A2 Therapeutic anti-melanoma compounds
01/02/2003EP1268541A1 7 human ovarian and ovarian cancer associated proteins
01/02/2003EP1268540A2 Proteins amf-1 to amf-10 and nucleic acids encoding same
01/02/2003EP1268539A2 Estrogen-regulated unconventional myosin-related protein: compositions and methods of use
01/02/2003EP1268536A1 Tcf responsive element
01/02/2003EP1268530A1 Hepatitis b core antigen fusion proteins
01/02/2003EP1268528A2 Human genes and expression products
01/02/2003EP1268510A2 Method and materials relating to insulin-like growth factor binding protein-like polypeptides and polynucleotides
01/02/2003EP1268507A1 Antisense modulation of e2f transcription factor 1 expression
01/02/2003EP1267954A1 Medical devices suitable for gene therapy regimens
01/02/2003EP1267945A2 Compositions containing genetically modified lung cancer cells expressing a tgf-beta inhibitor
01/02/2003EP1267944A1 Systemic gene delivery vehicles for the treatment of tumors
01/02/2003EP1267933A2 Sensitization of cells to cytotoxic agents using oligonucleotides directed to nucleotide excision repair or transcritpion coupled repair genes
01/02/2003EP1267924A2 Immunotherapeutic methods and compositions
01/02/2003EP1267917A1 Angiogenic onchocerca volvulus proteins and uses thereof
01/02/2003EP1267914A1 Use of lyosomal acid lipase for treating atherosclerosis and related diseases
01/02/2003EP1267910A2 Methods for inducing angiogenesis using morphogenic proteins and stimulatory factors
01/02/2003EP1267899A2 Salmonella vaccine materials and methods
01/02/2003EP1267834A1 Cationic liposomes
01/02/2003EP1267800A1 Methods of modulating hair growth
01/02/2003EP1267616A1 Methods of modulating hair growth
01/02/2003EP1115886A4 Secreted renilla luciferase
01/02/2003EP0930896B1 Method for tolerizing a mammalian patient to administration of gene therapy virus vectors
01/02/2003EP0745131B1 Targeting gene therapy
01/02/2003EP0723440B1 Therapeutic delivery compositions and methods of use thereof
01/01/2003CN1388829A High efficiency retroviral vector which contains genetically engineered cellular non-coding sequence harboring splicing acceptor
01/01/2003CN1388248A Adenovirus proliferated specifically inside tumor cell to express interferon in high efficiency and its construction method
01/01/2003CN1388247A Method of strengthening specific destination gene expression of cell
01/01/2003CN1097634C Interleukin-6 active inhibitor
12/2002
12/31/2002USRE37952 Grb3-3 cDNA and polypeptides
12/31/2002US6500945 Nucleotides having chiral phosphorus linkages
12/31/2002US6500941 Secreted by human breast cancer mda-mb-175 cells, leads to the formation of a constitutive active receptor complex and stimulates these cells in an autocrine manner
12/31/2002US6500937 Plasmid or vector; sequence encodes mammastatin; useful in the diagnosis and treatment of breast cancer
12/31/2002US6500919 Melanoma associated antigenic polypeptide, epitopes thereof and vaccines against melanoma
12/31/2002US6500807 Gene therapy
12/31/2002US6500662 Infectious cdna clones of positive polarity rna viruses and the construction of vaccines, in particular, swine vaccines, using such cdna clones
12/31/2002US6500641 Expression vector wherein said expression vector comprises a polynucleotide promoter sequence, a polynucleotide encoding a signal sequence, a polynucleotide encoding an antigen protein or peptide, a polynucleotide encoding a cell binding element,
12/31/2002US6500436 Administering botulinium toxin component coupled to substance p
12/31/2002US6500432 Method to enhance an immune response of nucleic acid vaccination
12/31/2002US6500422 Methods for preventing graft rejection in transplantation and for producing a universal gene therapy host cell using lymphocyte activation (LAG-3)
12/31/2002US6500421 Combination of the antifolate and the nucleoside transport inhibitor selects in vivo for the genetically modified hematopoietic progenitor cells
12/31/2002US6500419 Method for introducing and expressing RNA in animal cells
12/29/2002CA2392383A1 A complex comprising ocif and polysaccharide